© International Union of Biochemistry and Molecular Biology, Inc.
Edited By: Angelo Azzi
Impact Factor: 4.592
ISI Journal Citation Reports © Ranking: 2014: 26/128 (Endocrinology & Metabolism); 60/290 (Biochemistry & Molecular Biology)
Online ISSN: 1872-8081
Cinnamaldehyde supplementation prevents fasting-induced hyperphagia, lipid accumulation, and inflammation in high-fat diet-fed mice
Mitochondrial ascorbic acid prevents mitochondrial O2.− formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms
Prophylactic and abundant intake of α-lipoic acid causes hepatic steatosis and should be reconsidered in usage as an anti-aging drug
Inhibition of succinate dehydrogenase sensitizes cyclin E-driven ovarian cancer to CDK inhibition
Tocotrienol and cancer metastasis
Cardiac troponins—Translational biomarkers in cardiology: Theory and practice of cardiac troponin high-sensitivity assays
Recently Published Issues
IUBMB Joint Virtual Issue on Cancer Therapies
We’re pleased to present a new Joint Virtual Issue on Cancer Therapies in celebration of the IUBMB 2015 Miami Winter Symposium, featuring articles from Biofactors, Biotechnology and Applied Biochemistry, and IUBMB Life.
2015 BioFactors Young Investigator Award
On behalf of the IUBMB, BioFactors and Wiley, it is with great pleasure and honor that we announce Shilpa Thakur as the recipient of the 2015 BioFactors - Wiley Young Investigator Award for her article, Regulation at multiple levels controls the expression of folate transporters in liver cells in conditions of ethanol exposure and folate deficiency.
Shilpa Thakur is a Ph.D student in the Department of Biochemistry, Post Graduate Institute of Medical Education and Research, in Chandigarh, India. She completed her Bachelor’s and Masters' degree in Biotechnology and thereafter joined the Ph.D program under the guidance of Dr. Jyotdeep Kaur, Additional Professor in the Department of Biochemistry. As a part of her thesis work, Dr. Thakur has examined various regulatory mechanisms underlying the effects of folate deficiency and ethanol exposure on folate transport, and has gained expertise in the field of molecular biology and epigenetics during her Ph.D tenure. Presently, Dr. Thakur’s laboratory is focusing on folate deficiency and epigenetic regulation of some imprinting genes.
Shilpa Thakur will be honored with the 2015 BioFactors - Wiley Young Investigator Award at the 23rd International Union for Biochemistry and Molecular Biology (IUBMB) Congress and 44th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology in Foz do Iguaçu, Brazil from August 24th to 28th, 2015, and her award-winning article will be FREELY available online through the conference.
Please join us in congratulating Shipla Thakur as the recipient of the annual BioFactors– Wiley Young Investigator Award!
Open Access Highlight
Click below to read this OnlineOpen Review Article in BioFactors for FREE:
Novel insights on interactions between folate and lipid metabolism
Robin P. da Silva, Karen B. Kelly, Ala Al Rajabi, René L. Jacobs
Volume 40, Issue 3, May/June 2014
Folate is an essential B vitamin required for the maintenance of AdoMet-dependent methylation. The liver is responsible for many methylation reactions that are used for post-translational modifications of proteins, methylation of DNA, and the synthesis of hormones, creatine, carnitine, and phosphatidylcholine. Conditions where methylation capacity is compromised, including folate deficiency, are associated with impaired phospatidylcholine synthesis resulting in non-alcoholic fatty liver disease and steatohepatitis. Read the full article FREE!
Now in EarlyView
Fructooligosaccharides suppress high-fat diet-induced fat accumulation in C57BL/6J mice
Yuko Nakamura, Midori Natsume, Akiko Yasuda, Mihoko Ishizaka, Keiko Kawahata, Jinichiro Koga
Alterations in human muscle protein metabolism with aging: Protein and exercise as countermeasures to offset sarcopenia
Tyler A. Churchward-Venne, Leigh Breen, Stuart M. Phillips
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite
Andrea Guidarelli, Liana Cerioni, Mara Fiorani, Catia Azzolini, Orazio Cantoni
ATP-binding cassette transporters in live
Katrin Wlcek, Bruno Stieger
A DAF-16/FoxO3a-dependent longevity signal is initiated by antioxidants
Juewon Kim, Naoko Ishihara, Tae Ryong Lee