Journal of Tissue Engineering and Regenerative Medicine

Cover image for Vol. 9 Issue 11

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Rui L. Reis

Impact Factor: 5.199

ISI Journal Citation Reports © Ranking: 2014: 5/76 (Engineering Biomedical); 5/21 (CELL & TISSUE ENGINEERING); 17/162 (Biotechnology & Applied Microbiology); 44/184 (Cell Biology)

Online ISSN: 1932-7005

  1. Research Articles

    1. Effect of pore sizes of PLGA scaffolds on mechanical properties and cell behaviour for nucleus pulposus regeneration in vivo

      Hye Yun Kim, Ha Neul Kim, So Jin Lee, Jeong Eun Song, Soon Yong Kwon, Jin Wha Chung, Dongwon Lee and Gilson Khang

      Article first published online: 11 MAR 2014 | DOI: 10.1002/term.1856

    2. Generation of tunable glycosaminoglycan hydrogels to mimic extracellular matrices

      A. Herrero-Mendez, T. Palomares, B. Castro, J. Herrero and A. Alonso-Varona

      Article first published online: 5 MAR 2014 | DOI: 10.1002/term.1883

    3. Biofunctional hydrogels for skeletal muscle constructs

      Apoorva S. Salimath and Andrés J. García

      Article first published online: 26 FEB 2014 | DOI: 10.1002/term.1881

    4. Fluorescent imaging of endothelial cells in bioengineered blood vessels: the impact of crosslinking of the scaffold

      Guoguang Niu, Etai Sapoznik, Peng Lu, Tracy Criswell, Aaron M. Mohs, Ge Wang, Sang-Jin Lee, Yong Xu and Shay Soker

      Article first published online: 26 FEB 2014 | DOI: 10.1002/term.1876

    5. Generation of composites for bone tissue-engineering applications consisting of gellan gum hydrogels mineralized with calcium and magnesium phosphate phases by enzymatic means

      Timothy E. L. Douglas, Grzegorz Krawczyk, Elzbieta Pamula, Heidi A. Declercq, David Schaubroeck, Miroslaw M. Bucko, Lieve Balcaen, Pascal Van Der Voort, Vitaliy Bliznuk, Natasja M. F. van den Vreken, Mamoni Dash, Rainer Detsch, Aldo R. Boccaccini, Frank Vanhaecke, Maria Cornelissen and Peter Dubruel

      Article first published online: 21 FEB 2014 | DOI: 10.1002/term.1875

    6. Controlled tubulogenesis from dispersed ureteric bud-derived cells using a micropatterned gel

      Peter V. Hauser, Masaki Nishikawa, Hiroshi Kimura, Teruo Fujii and Norimoto Yanagawa

      Article first published online: 29 JAN 2014 | DOI: 10.1002/term.1871

    7. Genipin-crosslinked gelatin–silk fibroin hydrogels for modulating the behaviour of pluripotent cells

      Wei Sun, Tania Incitti, Claudio Migliaresi, Alessandro Quattrone, Simona Casarosa and Antonella Motta

      Article first published online: 29 JAN 2014 | DOI: 10.1002/term.1868

    8. Preferential tendon stem cell response to growth factor supplementation

      Carolyn Holladay, Sunny-Akogwu Abbah, Colm O'Dowd, Abhay Pandit and Dimitrios I. Zeugolis

      Article first published online: 29 JAN 2014 | DOI: 10.1002/term.1852

    9. In vivo vascularization of cell sheets provided better long-term tissue survival than injection of cell suspension

      Ryohei Takeuchi, Yosuke Kuruma, Hidekazu Sekine, Izumi Dobashi, Masayuki Yamato, Mitsuo Umezu, Tatsuya Shimizu and Teruo Okano

      Article first published online: 28 JAN 2014 | DOI: 10.1002/term.1854

    10. Glottic regeneration with a tissue-engineering technique, using acellular extracellular matrix scaffold in a canine model

      Morimasa Kitamura, Shigeru Hirano, Shin-ichi Kanemaru, Yoshiharu Kitani, Satoshi Ohno, Tsuyoshi Kojima, Tatsuo Nakamura, Juichi Ito, Clark A. Rosen and Thomas W. Gilbert

      Article first published online: 8 JAN 2014 | DOI: 10.1002/term.1855

    11. In vitro vascularization of a combined system based on a 3D printing technique

      Xinru Zhao, Libiao Liu, Jiayin Wang, Yufan Xu, Weiming Zhang, Gilson Khang and Xiaohong Wang

      Article first published online: 8 JAN 2014 | DOI: 10.1002/term.1863

    12. SPECT vs. PET monitoring of bone defect healing and biomaterial performance in vivo

      Manuela Ventura, Gerben M. Franssen, Egbert Oosterwijk, Otto C. Boerman, John A. Jansen and X. Frank Walboomers

      Article first published online: 6 JAN 2014 | DOI: 10.1002/term.1862

    13. Abdominal wall reconstruction by a regionally distinct biocomposite of extracellular matrix digest and a biodegradable elastomer

      Keisuke Takanari, Yi Hong, Ryotaro Hashizume, Alexander Huber, Nicholas J. Amoroso, Antonio D'Amore, Stephen F. Badylak and William R. Wagner

      Article first published online: 27 DEC 2013 | DOI: 10.1002/term.1834

    14. Peritoneal cell sheets composed of mesothelial cells and fibroblasts prevent intra-abdominal adhesion formation in a rat model

      Kunio Kawanishi, Masayuki Yamato, Ryouichi Sakiyama, Teruo Okano and Kosaku Nitta

      Article first published online: 10 DEC 2013 | DOI: 10.1002/term.1860

    15. In-body tissue-engineered collagenous connective tissue membranes (BIOSHEETs) for potential corneal stromal substitution

      Naoaki Takiyama, Takeshi Mizuno, Ryosuke Iwai, Masami Uechi and Yasuhide Nakayama

      Article first published online: 10 DEC 2013 | DOI: 10.1002/term.1859

    16. Adipose- and bone marrow-derived mesenchymal stem cells display different osteogenic differentiation patterns in 3D bioactive glass-based scaffolds

      Subha N. Rath, Patcharakamon Nooeaid, Andreas Arkudas, Justus P. Beier, Leonie A. Strobel, Andreas Brandl, Judith A. Roether, Raymund E. Horch, Aldo R. Boccaccini and Ulrich Kneser

      Article first published online: 3 DEC 2013 | DOI: 10.1002/term.1849

    17. Establishment and characterization of the Masquelet induced membrane technique in a rat femur critical-sized defect model

      D. Henrich, C. Seebach, C. Nau, S. Basan, B. Relja, K. Wilhelm, A. Schaible, J. Frank, J. Barker and I. Marzi

      Article first published online: 8 NOV 2013 | DOI: 10.1002/term.1826

    18. Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds

      A. M. Leferink, W. J. Hendrikson, J. Rouwkema, M. Karperien, C. A. van Blitterswijk and L. Moroni

      Article first published online: 8 NOV 2013 | DOI: 10.1002/term.1842

    19. Segmental composite porous scaffolds with either osteogenesis or anti-bone resorption properties tested in a rabbit ulna defect model

      Shihui Chen, Poying Lau, Ming Lei, Jiang Peng, Tao Tang, Xiaohong Wang, Ling Qin and Shekhar-Madhukar Kumta

      Article first published online: 6 NOV 2013 | DOI: 10.1002/term.1828

    20. Transplantation of cancerous cell sheets effectively generates tumour-bearing model mice

      Jun Akimoto, Soichi Takagi, Masamichi Nakayama, Ayumi Arauchi, Masayuki Yamato and Teruo Okano

      Article first published online: 6 NOV 2013 | DOI: 10.1002/term.1850

    21. In vitro and in vivo co-culture of chondrocytes and bone marrow stem cells in photocrosslinked PCL–PEG–PCL hydrogels enhances cartilage formation

      Chao-Yin Ko, Kuan-Lin Ku, Shu-Rui Yang, Tsai-Yu Lin, Sydney Peng, Yu-Shiang Peng, Ming-Huei Cheng and I-Ming Chu

      Article first published online: 6 NOV 2013 | DOI: 10.1002/term.1846

    22. Development of volume-stable adipose tissue constructs using polycaprolactone-based polyurethane scaffolds and fibrin hydrogels

      Katharina Wittmann, Katharina Storck, Christian Muhr, Helena Mayer, Sybille Regn, Rainer Staudenmaier, Hinrich Wiese, Gerhard Maier, Petra Bauer-Kreisel and Torsten Blunk

      Article first published online: 30 OCT 2013 | DOI: 10.1002/term.1830

    23. Collagen–chitosan–laminin hydrogels for the delivery of insulin-producing tissue

      Kimberly McEwan, Donna T. Padavan, Cara Ellis, Joanne E. McBane, Branka Vulesevic, Gregory S. Korbutt and Erik J. Suuronen

      Article first published online: 30 OCT 2013 | DOI: 10.1002/term.1829

    24. Dynamic three-dimensional micropatterned cell co-cultures within photocurable and chemically degradable hydrogels

      Shinji Sugiura, Jae Min Cha, Fumiki Yanagawa, Pinar Zorlutuna, Hojae Bae and Ali Khademhosseini

      Article first published online: 30 OCT 2013 | DOI: 10.1002/term.1843

    25. Three-dimensional spatial configuration of tumour cells confers resistance to chemotherapy independent of drug delivery

      Pamela H. S. Tan, Su Shin Chia, Siew Lok Toh, James C. H. Goh and Saminathan Suresh Nathan

      Article first published online: 30 OCT 2013 | DOI: 10.1002/term.1800

    26. Size matters: effects of PLGA-microsphere size in injectable CPC/PLGA on bone formation

      Hongbing Liao, Rosa P. Félix Lanao, Jeroen J. J. P. van den Beucken, Nuo Zhou, Sanne K. Both, Joop G. C. Wolke and John A. Jansen

      Article first published online: 29 OCT 2013 | DOI: 10.1002/term.1840

    27. Platelet-derived growth factor BB gene-released scaffolds: biosynthesis and characterization

      Yufeng Zhang, Yihui Ma, Chengtie Wu, Richard J. Miron and Xiangrong Cheng

      Article first published online: 16 OCT 2013 | DOI: 10.1002/term.1825

    28. Optimizing a multifunctional microsphere scaffold to improve neural precursor cell transplantation for traumatic brain injury repair

      Nolan B. Skop, Frances Calderon, Cheul H. Cho, Chirag D. Gandhi and Steven W. Levison

      Article first published online: 9 OCT 2013 | DOI: 10.1002/term.1832

    29. Evaluation of six synthetic surgical meshes implanted subcutaneously in a rat model

      Nicholas Bryan, Helen Ashwin, Rui Chen, Neil J. Smart, Yves Bayon, Stephen Wohlert and John A. Hunt

      Article first published online: 7 OCT 2013 | DOI: 10.1002/term.1807

    30. Design and validation of a dynamic cell-culture system for bone biology research and exogenous tissue-engineering applications

      Alexander C. Allori, Edward H. Davidson, Derek D. Reformat, Alexander M. Sailon, James Freeman, Adam Vaughan, David Wootton, Elizabeth Clark, John L. Ricci and Stephen M. Warren

      Article first published online: 11 SEP 2013 | DOI: 10.1002/term.1810

    31. Design and characterization of a biodegradable double-layer scaffold aimed at periodontal tissue-engineering applications

      João F. Requicha, Carlos A. Viegas, Shantesh Hede, Isabel B. Leonor, Rui L. Reis and Manuela E. Gomes

      Article first published online: 1 SEP 2013 | DOI: 10.1002/term.1816

    32. A novel oxysterol promotes bone regeneration in rabbit cranial bone defects

      Akishige Hokugo, Sarah Sorice, Farhad Parhami, Anisa Yalom, Andrew Li, Patricia Zuk and Reza Jarrahy

      Article first published online: 29 AUG 2013 | DOI: 10.1002/term.1799

    33. Effects of parathyroid hormone 1-34 on osteogenic and chondrogenic differentiation of human fracture haematoma-derived cells in vitro

      Yoshihiro Dogaki, Sang Yang Lee, Takahiro Niikura, Takaaki Koga, Etsuko Okumachi, Kotaro Nishida, Ryosuke Kuroda and Masahiro Kurosaka

      Article first published online: 29 AUG 2013 | DOI: 10.1002/term.1818

    34. In vitro two-dimensional and three-dimensional tenocyte culture for tendon tissue engineering

      Yiwei Qiu, Xiao Wang, Yaonan Zhang, Andrew J. Carr, Liwei Zhu, Zhidao Xia and Afsie Sabokbar

      Article first published online: 29 AUG 2013 | DOI: 10.1002/term.1791

    35. Comparison of different cooling rates for fibroblast and keratinocyte cryopreservation

      Yahaira Naaldijk, Annett Friedrich-Stöckigt, Sebastian Sethe and Alexandra Stolzing

      Article first published online: 21 AUG 2013 | DOI: 10.1002/term.1815

    36. Hydrocortisone effect on hyaluronate synthesis in a self-assembled human dermal equivalent

      Madhura Deshpande, Suzanne Papp, Lana Schaffer and Tara Pouyani

      Article first published online: 16 AUG 2013 | DOI: 10.1002/term.1809

    37. Ibuprofen-loaded poly(trimethylene carbonate-co-ε-caprolactone) electrospun fibres for nerve regeneration

      Liliana R. Pires, Vincenzo Guarino, Maria J. Oliveira, Cristina C. Ribeiro, Mário A Barbosa, Luigi Ambrosio and Ana Paula Pêgo

      Article first published online: 16 AUG 2013 | DOI: 10.1002/term.1792

    38. The incorporation of growth factor and chondroitinase ABC into an electrospun scaffold to promote axon regrowth following spinal cord injury

      Raymond J. Colello, Woon N. Chow, John W. Bigbee, Charles Lin, Dustin Dalton, Damien Brown, Balendu Shekhar Jha, Bruce E. Mathern, Kangmin D. Lee and David G. Simpson

      Article first published online: 15 AUG 2013 | DOI: 10.1002/term.1805

    39. Functional analysis in vivo of engineered valved venous conduit with decellularized matrix and two bone marrow-derived progenitors in sheep

      Jian-Ming Yuan, Shao-Hu Xiong, Zhen Liu, Yu Wen, Rui-Shan Dang, Man-Ru Shen, Yong-Zhen Zhang, Xi Zhang, Xiang-Qun Yang and Chuan-Sen Zhang

      Article first published online: 31 JUL 2013 | DOI: 10.1002/term.1748

    40. Pancreatic islet differentiation of human embryonic stem cells by microRNA overexpression

      Reyhaneh Lahmy, Masoud Soleimani, Mohammad H. Sanati, Mehrdad Behmanesh, Fatemeh Kouhkan and Naser Mobarra

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1787

    41. Epidermal-like architecture obtained from equine keratinocytes in three-dimensional cultures

      Ruchi Sharma, Safia Z. Barakzai, Sarah E. Taylor and F. Xavier Donadeu

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1788

    42. A compact and automated ex vivo vessel culture system for the pulsatile pressure conditioning of human saphenous veins

      Marco Piola, Francesca Prandi, Nina Bono, Monica Soncini, Eleonora Penza, Marco Agrifoglio, Gianluca Polvani, Maurizio Pesce and Gianfranco Beniamino Fiore

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1798

    43. The essential role of annexin A1 mimetic peptide in the skin allograft survival

      Rodrigo Antonio Parra Teixeira, Kallyne Kioko Oliveira Mimura, Leandro Pires Araujo, Karin Vicente Greco and Sonia Maria Oliani

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1773

    44. Pharmacological priming of adipose-derived stem cells for paracrine VEGF production with deferoxamine

      Guei-Sheung Liu, Hitesh M. Peshavariya, Masayoshi Higuchi, Elsa C. Chan, Gregory J. Dusting and Fan Jiang

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1796

    45. Podocalyxin-like protein 1 is a relevant marker for human c-kitpos cardiac stem cells

      Isabel Moscoso, Naiara Tejados, Olga Barreiro, Pilar Sepúlveda, Alberto Izarra, Enrique Calvo, Akaitz Dorronsoro, Juan Manuel Salcedo, Rafael Sádaba, Antonio Díez-Juan, César Trigueros and Antonio Bernad

      Article first published online: 30 JUL 2013 | DOI: 10.1002/term.1795

    46. Middle ear mucosal regeneration with three-dimensionally tissue-engineered autologous middle ear cell sheets in rabbit model

      Yuichiro Yaguchi, Daisuke Murakami, Masayuki Yamato, Takanori Hama, Kazuhisa Yamamoto, Hiromi Kojima, Hiroshi Moriyama and Teruo Okano

      Article first published online: 28 JUL 2013 | DOI: 10.1002/term.1790

    47. In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells

      Benedikt Weber, Debora Kehl, Ulrich Bleul, Luc Behr, Sébastien Sammut, Laura Frese, Agnieszka Ksiazek, Josef Achermann, Gerald Stranzinger, Jérôme Robert, Bart Sanders, Michele Sidler, Chad E. Brokopp, Steven T. Proulx, Thomas Frauenfelder, Roman Schoenauer, Maximilian Y. Emmert, Volkmar Falk and Simon P. Hoerstrup

      Article first published online: 24 JUL 2013 | DOI: 10.1002/term.1781

    48. Dependence of macrophage superoxide release on the pulse amplitude of an applied pressure regime: a potential factor at the soft tissue–implant interface

      Hainsworth Y. Shin, Danielle M. Frechette, Nathan Rohner, Xiaoyan Zhang, David A. Puleo and Lars M. Bjursten

      Article first published online: 24 JUL 2013 | DOI: 10.1002/term.1789

    49. Development of a novel smart scaffold for human skeletal muscle regeneration

      Rishma Shah, Jonathan C. Knowles, Nigel P. Hunt and Mark P. Lewis

      Article first published online: 23 JUL 2013 | DOI: 10.1002/term.1780

    50. Characterization of chondrocyte sheets prepared using a co-culture method with temperature-responsive culture inserts

      Mami Kokubo, Masato Sato, Masayuki Yamato, Genya Mitani, Toshiharu Kutsuna, Goro Ebihara, Teruo Okano and Joji Mochida

      Article first published online: 19 JUL 2013 | DOI: 10.1002/term.1764

    51. Transforming growth factor-beta1 inhibits tissue engineering cartilage absorption via inducing the generation of regulatory T cells

      Chichi Li, Wei Bi, Yiming Gong, Xiaojun Ding, Xuehua Guo, Jian Sun, Lei Cui and Youcheng Yu

      Article first published online: 19 JUL 2013 | DOI: 10.1002/term.1777

    52. The influence of platelet-rich plasma on myogenic differentiation

      Michael J. McClure, Koyal Garg, David G. Simpson, John J. Ryan, Scott A. Sell, Gary L. Bowlin and Jeffery J. Ericksen

      Article first published online: 19 JUL 2013 | DOI: 10.1002/term.1755

    53. Breast epithelial cell infiltration in enhanced electrospun silk scaffolds

      Yas Maghdouri-White, Lynne W. Elmore, Gary L. Bowlin and Didier Dréau

      Article first published online: 24 JUN 2013 | DOI: 10.1002/term.1778

    54. Comparative study of the osteogenic ability of four different ceramic constructs in an ectopic large animal model

      Véronique Viateau, Mathieu Manassero, Luc Sensébé, Alain Langonné, David Marchat, Delphine Logeart-Avramoglou, Hervé Petite and Morad Bensidhoum

      Article first published online: 20 JUN 2013 | DOI: 10.1002/term.1782

    55. Computational model for the analysis of cartilage and cartilage tissue constructs

      David W. Smith, Bruce S. Gardiner, John B. Davidson and Alan J. Grodzinsky

      Article first published online: 20 JUN 2013 | DOI: 10.1002/term.1751

    56. The effectiveness of the controlled release of simvastatin from β-TCP macrosphere in the treatment of OVX mice

      Joshua Chou, Tomoko Ito, Makoto Otsuka, Besim Ben-Nissan and Bruce Milthorpe

      Article first published online: 20 JUN 2013 | DOI: 10.1002/term.1784

    57. Chondrogenic potential of human dermal fibroblasts in a contractile, soft, self-assembling, peptide hydrogel

      Bianca M. Bussmann, Sven Reiche, Núria Marí-Buyé, Cristina Castells-Sala, Hans Jörg Meisel and Carlos E. Semino

      Article first published online: 4 JUN 2013 | DOI: 10.1002/term.1766

    58. Effect of platelet-rich plasma (PRP) concentration on proliferation, neurotrophic function and migration of Schwann cells in vitro

      Canbin Zheng, Qingtang Zhu, Xiaolin Liu, Xijun Huang, Caifeng He, Li Jiang, Daping Quan, Xiang Zhou and Zhaowei Zhu

      Article first published online: 31 MAY 2013 | DOI: 10.1002/term.1756

    59. Fibrin biomatrix-conjugated platelet-derived growth factor AB accelerates wound healing in severe thermal injury

      Rainer Mittermayr, Ludwik Branski, Martina Moritz, Marc G. Jeschke, David N. Herndon, Daniel Traber, Jason Schense, Jörg Gampfer, Andreas Goppelt and Heinz Redl

      Article first published online: 31 MAY 2013 | DOI: 10.1002/term.1749

    60. Behaviour of human mesenchymal stem cells on chemically synthesized HA–PCL scaffolds for hard tissue regeneration

      Vincenzo D'Antò, Maria Grazia Raucci, Vincenzo Guarino, Stefano Martina, Rosa Valletta and Luigi Ambrosio

      Article first published online: 31 MAY 2013 | DOI: 10.1002/term.1768

    61. Poly-ε-caprolactone scaffold and reduced in vitro cell culture: beneficial effect on compaction and improved valvular tissue formation

      Marieke M. C. P. Brugmans, Anita Driessen-Mol, Mirjam P. Rubbens, Martijn A. J. Cox and Frank P. T. Baaijens

      Article first published online: 15 MAY 2013 | DOI: 10.1002/term.1753