Journal of Tissue Engineering and Regenerative Medicine

Author Guidelines

Copyright Transfer Agreement
Permission Request Form
OnlineOpen Order Form
Conflict of Interest Disclosure Form

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Author Guidelines

Manuscript Submission. The Journal of Tissue Engineering and Regenerative Medicine operates an online submission and peer review system that allows authors to submit articles online and track their progress via a web interface. Please read the remainder of these instructions to authors and then click http://mc.manuscriptcentral.com/term to navigate to the Journal of Tissue Engineering and Regenerative Medicine online submission site. Further information can be found there, including a detailed description of the coverage of TERM. All articles must be submitted via the online system.

For assistance, please contact our Editorial office (in the office of Prof. Rui L. Reis at the University of Minho): TERM@wiley.co.uk

Each paper will be evaluated by three independent reviewers. Authors are welcome to submit the names and contact details of up to three suggested reviewers, using the online system, however please note that the Editors are not obliged to use the suggested reviewers. Only those contributions that the Editor-in-Chief or the relevant Associate Editor considers to be of sufficient interest will be sent out for peer review. The criteria for this are based on the aims and scope of the journal, its high quality standards, the originality and potential outcomes of the work, and its significance to the multidisciplinary research fields related to the Journal of Tissue Engineering and Regenerative Medicine.

Submission is considered on the conditions that papers are previously unpublished, and are not offered simultaneously elsewhere; that all authors have read and approved the content, and all authors have also declared all competing interests; and that the work complies with Ethical Policies of the journal, and has been conducted under internationally accepted ethical standards after relevant ethical review. It is highly recommended you read this policy and complete any necessary documentation prior to your submission

If a paper has more than 7 authors, the inclusion of each name must be clearly justified. Methods of recognizing contributors have been proposed ( Lancet 1995; 345: 668). The Editors believe that those with a peripheral association with the work should simply be acknowledged ( BJS 2000; 87: 1284-6).

File types. Preferred formats for the text and tables of your manuscript are .doc, .rtf. Figures must be provided in .tiff or .eps format.

Upon acceptance, authors must supply the below forms immediately, by completing, scanning and emailing them to the Content Editor, quoting the journal name and the manuscript code on each form:

• a Copyright Transfer Agreement with original signature(s).
• If the manuscript contains extracts, including illustrations, from other copyright works (including material from online or intranet sources) it is the author's responsibility to obtain written permission from the owners of the publishing rights to reproduce such extracts using the Wiley Permission Request Form.
• For human clinical studies, written consent must be obtained from the patient, legal guardian or executor for publication of any detail or photograph that might identify an individual. Evidence of such consent must be submitted.
• If relevant, a Conflict of Interest Disclosure Form should be completed by each author.

Copies of these forms are available from the journal website and included in the first print issue of each volume.

Submitted material will not be returned to the author unless specifically requested.
Content Editor: Marydale Manato - mmanato@wiley.com

Ethics. Human investigation and animal experiments must have local ethics committee approval. TERM will not publish an article if appropriate ethical standards have not been met.

Manuscript Style. The language of the journal is English. Please ensure that your manuscript has been checked by a native English speaker, or an English language service, if there is concern for grammatical or other errors. All submissions must have a title, be double-line spaced with type no smaller than 12 point, and have a margin of 3cm all round. Tables must be on separate pages after the reference list, and not be incorporated into the main text. Figures should be uploaded as separate image files.

• The title page must list the full title, short title of up to 70 characters and names and affiliations of all authors. Give the full address, including email, telephone and fax, of the author who is the senior author due to check the proofs.
• Include the name(s) of any sponsor(s) of the research contained in the paper, along with grant number(s) if applicable.
• Supply an abstract of up to 250 words for all articles. An abstract should be a concise summary of the whole paper, not just the conclusions, and it must be understandable without reference to the rest of the paper. It should contain no citation to any other published work.
• Include up to eight keywords that describe your paper for indexing purposes.
• Number the sections and sub-sections of papers , in the style: 1. Introduction, 2. Materials and Methods, 2.1. Scaffold Preparation, 2.2. Cell Sources… 3. Results and Discussion, etc.
• A concise introduction is required of the present state-of-the-art, the background to the subject, its significance and its relationship to earlier works, with well selected and relevant references.
• Materials and methods should be presented with clarity and detail in order to allow others to reproduce the work. State the original and important findings in the results. Illustrate these with figures or tables where necessary but keep these to a minimum.
• Results and discussion may be combined as one section. Discuss the principal conclusions drawn from the results and their important implications.
• Use Chemical Abstracts nomenclature for chemical names and structures. Use proper or proprietary names with caution. Common acronyms for biomedical names are acceptable but define all others when first mentioned. Define abbreviations when first mentioned and do not use in the title or abstract. Define non-standard units.
• Keep acknowledgements brief and place them at the end of the paper.
• Abbreviations; Avoid using abbreviations. Terms that are mentioned frequently may be abbreviated but only if this does not impair comprehension. Abbreviations must be used consistently and must be defined on first use.
• Numbers and units; Provide absolute numbers; percentages may be given in addition, but never on their own. Use the decimal point, not a comma, for example 5.7. Use a space and not a comma after thousands and multiples thereof, for example 10 000. Use SI units (International System of Units).

Types of Manuscripts. TERM will publish original research papers on all topics that fall within the aims and scope. In addition it will publish peer-reviewed authoritative reviews and perspectives articles submitted by world recognized experts that are invited to or wish to submit, with the aim of sharing opinions, establishing good practice and stimulating discussions of emerging topics or the future evolution of a certain area within the remit of TERM. In order to make sure that new and relevant results are published as quickly as they deserve, while still observing the high peer-review standards of TERM, short communications will also be accepted by the journal. Clinical case studies describing the application of these technologies in human patients are also welcomed.

Original research papers. These should not exceed eight printed pages including typically a maximum of six figures and/or four tables and 30/40 references (one page comprises 860 words or the equivalent in illustrative and tabular material).

Short communications. These must be complete, self-contained papers, and not preliminary reports. They should report on particularly new and relevant results that deserve to be published quickly, and should not exceed 2 printed pages including typically a maximum of 2 figures and/or two tables and 10 to 15 references. To exceed the limit may delay acceptance or publication of the paper, although exceptions may be considered. These papers should be organized in the form of an extended abstract, without sub-headings, but with a clear order of presentation and adequate detail of the relevant experimental methods and the results obtained.

Clinical case studies. These should not exceed eight printed pages including typically a maximum of six figures and/or four tables and 30/40 references, (where one page comprises 860 words or the equivalent in illustrative and tabular material). The reported cases should be highly relevant to the field of TERM, namely with regard to their novelty. Authors should state clearly how many patients were involved in the study and, whenever relevant, a statistical analysis should be included, as well as a detailed section on the experimental methods and ethical protocols followed during the study.

Reviews. These will usually be written by leaders in the field, and at the invitation of the Editors. Unsolicited reviews and manuscripts, especially when based on major conference Plenary/Keynote Lectures will be welcome but authors wishing to submit these are requested to consult the Editor-in-Chief beforehand, ideally prior to commencement of writing. They should start by submitting a synopsis for evaluation. Reviews should include a Table of Contents, and will normally be limited to 12 to 15 printed pages, that is to 10,500 to 13,000 words including references.

Perspectives. These will be short authoritative reviews presenting an outlook on the likely evolution of a chosen subject area. They will usually be written by leaders in the field, typically by invitation. Unsolicited perspective papers may be considered if they are of special relevance to the field and the authors are recognized or clearly emerging in that specific scientific area. Again, authors wishing to submit such articles are requested to consult the Editor-in-Chief beforehand, ideally prior to commencement of writing. They should start by submitting a short synopsis for evaluation. Perspectives will normally be limited to 3 to 6 pages, that is to 2,600 to 5,200 words including references.

Reference style. References should be quoted in the text as name and year e.g. (Smith et al ., 2006), and listed at the end of the paper alphabetically. Where three or more authors are listed in the reference list, please cite in the text as (Collins et al., 1998). If 2 authors are listed then both should be shown in the text (Collins and Williams 2001).

All references must be complete and accurate, and reference to abstracts and personal communications is strongly discouraged. The Journal of Tissue Engineering and Regenerative Medicine uses MEDLINE journal title abbreviations; to look up the correct abbreviation of a journal title, visit: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=journals

References should be listed in the following style:

Journal articles: Salgado AJ, Coutinho OP, Reis RL. 2004, Bone tissue engineering: State of the art and future trends, Macromol Biosci, 4: 743-765

Books: Reis RL. San Roman J. 2004, Biodegradable Systems in the Journal of Tissue Engineering and Regenerative Medicine, CRC Press, Boca Raton, FL, USA

Chapters in books: Gomes ME, Mikos AG, Reis RL. 2004, ‘Injectable Polymeric Scaffolds for Bone Tissue Engineering’ in Biodegradable Systems in Tissue Engineering and Regenerative Medicine, eds. Reis RL, San Roman J, CRC Press, Boca Raton, FL, USA; 29-38

Illustrations. Upload each figure as a separate file in either .tiff or .eps format, with the figure number and the top of the figure indicated. Compound figures e.g. 1a, b, c should be uploaded as one figure. Tints are not acceptable. Lettering must be of a reasonable size that would still be clearly legible upon reduction, and consistent within each figure and set of figures. Please supply artwork at the intended size for printing, sized to the text width of 84mm/single column, 176mm/double column. Where a key to symbols is required, please include this in the artwork itself, not in the figure legend. All illustrations must be supplied at the correct resolution:

• Black and white and colour photos - 300 dpi
• Graphs, drawings, etc - 800 dpi preferred; 600 dpi minimum
• Combinations of photos and drawings (black and white and colour) - 500 dpi

The cost of printing colour illustrations in the journal will be charged to the author, at a rate of £500 per page. If colour illustrations are supplied electronically in either TIFF or EPS format, they may be used in the PDF of the article at no cost to the author, even if this illustration was printed in black and white in the journal. The PDF will appear on Wiley Online Library.

Supporting information. Supporting information files for online-only publication are accepted by the journal. Guidelines and acceptable file formats may be found at http://authorservices.wiley.com/bauthor/suppmat.asp.

Copyright. To enable the publisher to disseminate the author's work to the fullest extent, the author must sign a Copyright Transfer Agreement, transferring copyright in the article from the author to the publisher, and submit the original signed agreement with the article presented for publication. A copy of the agreement to be used (which may be photocopied) can be found in the first issue of each volume of the Journal of Tissue Engineering and Regenerative Medicine. Copies may also be obtained from the journal editor or publisher, or may be printed from the journal website.

OnlineOpen. OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at: https://authorservices.wiley.com/bauthor/onlineopen_order.asp

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

Note to NIH and HHMI Grantees. Wiley-Blackwell will automatically deposit the accepted (not edited and typeset) version of primary research papers funded by these bodies to PubMedCentral. For NIH authors the papers are made freely available twelve months after acceptance and for HHMI authors six months after acceptance, for more details see our full policy statements: http://authorservices.wiley.com/bauthor/CTA.asp#NIH

Proofs and offprints. Proofs will be sent to the author for checking. This stage is to be used only to correct errors that may have been introduced during the production process. Prompt return of the corrected proofs, preferably within two days of receipt, will minimise the risk of the paper being held over to a later issue. Free access to the final PDF offprint or your article will be available via Author Services. Please therefore sign up for Author Services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers.