Factors affecting the success of next-generation sequencing in cytology specimens
Sinchita Roy-Chowdhuri, Rashmi S. Goswami, Hui Chen, Keyur P. Patel, Mark J. Routbort, Rajesh R. Singh, Russell R. Broaddus, Bedia A. Barkoh, Jawad Manekia, Hui Yao, L. Jeffrey Medeiros, Gregg Staerkel, Rajyalakshmi Luthra and John Stewart
Article first published online: 31 JUL 2015 | DOI: 10.1002/cncy.21597
Next-generation sequencing in cytology specimens is often challenging because of the limited sample volume. The failure of next-generation sequencing is multifactorial, and identifying these pre-analytical variables will allow better selection of cytology material and increase the frequency of successful testing.