Evaluation of intraoperative cytological assessment of bone resection margins in patients with oral squamous cell carcinoma
Markus Nieberler, Patrick Häusler, Enken Drecoll, Mechthild Stoeckelhuber, Herbert Deppe, Frank Hölzle, Andreas Kolk, Klaus-Dietrich Wolff, Marco Rainer Kesting and Gregor Weirich
Article first published online: 18 APR 2014 | DOI: 10.1002/cncy.21428
The current study evaluates the intraoperative cytological assessment of bone resection margins to control resection status in patients with bone-infiltrating oral squamous cell carcinomas. The work demonstrates that intraoperative cytological assessment of bone resection margins could supplement the intraoperative assessment of soft tissue margins through the immediate microscopic control of bony resection margins, enabling a guided reresection of positive bone margins during a surgical intervention to optimize surgical concepts, especially for patients with carcinoma, who receive primary reconstruction with osteo-(myo-)cutaneous microvascular transplants.