Autism Research

Cover image for Vol. 9 Issue 7

Early View (Online Version of Record published before inclusion in an issue)

Edited By: David G. Amaral, Ph.D

Online ISSN: 1939-3806

VIEW

  1. 1 - 71
  1. Short Reports

  2. Research Articles

    1. The stability and validity of automated vocal analysis in preverbal preschoolers with autism spectrum disorder

      Tiffany Woynaroski, D. Kimbrough Oller, Bahar Keceli-Kaysili, Dongxin Xu, Jeffrey A. Richards, Jill Gilkerson, Sharmistha Gray and Paul Yoder

      Version of Record online: 26 JUL 2016 | DOI: 10.1002/aur.1667

  3. Short Reports

    1. You have full text access to this OnlineOpen article
  4. Research Articles

    1. SLC9A9 Co-expression modules in autism-associated brain regions

      Jameson Patak, Jonathan L. Hess, Yanli Zhang-James, Stephen J. Glatt and Stephen V. Faraone

      Version of Record online: 21 JUL 2016 | DOI: 10.1002/aur.1670

    2. You have full text access to this OnlineOpen article
    3. Lack of replication of previous autism spectrum disorder GWAS hits in European populations

      Bàrbara Torrico, Andreas G. Chiocchetti, Elena Bacchelli, Elisabetta Trabetti, Amaia Hervás, Barbara Franke, Jan K. Buitelaar, Nanda Rommelse, Afsheen Yousaf, Eftichia Duketis, Christine M. Freitag, Rafaela Caballero-Andaluz, Amalia Martinez-Mir, Francisco G. Scholl, Marta Ribasés, ITAN, Agatino Battaglia, Giovanni Malerba, Richard Delorme, Marion Benabou, Elena Maestrini, Thomas Bourgeron, Bru Cormand and Claudio Toma

      Version of Record online: 15 JUL 2016 | DOI: 10.1002/aur.1662

    4. Non-ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study

      Tony Charman, Gregory S. Young, Jessica Brian, Alice Carter, Leslie J. Carver, Katarzyna Chawarska, Suzanne Curtin, Karen Dobkins, Mayada Elsabbagh, Stelios Georgiades, Irva Hertz-Picciotto, Ted Hutman, Jana M. Iverson, Emily J. Jones, Rebecca Landa, Suzanne Macari, Daniel S. Messinger, Charles A. Nelson, Sally Ozonoff, Celine Saulnier, Wendy L. Stone, Helen Tager-Flusberg, Sara Jane Webb, Nurit Yirmiya and Lonnie Zwaigenbaum

      Version of Record online: 15 JUL 2016 | DOI: 10.1002/aur.1669

      Scientific Abstract

      We characterized developmental outcomes of a large sample of siblings at familial high-risk of autism spectrum disorder (ASD), who themselves did not have ASD (n = 859), and low-risk controls with no family history of ASD (n = 473). We report outcomes at age 3 years using the Mullen Scales of Early Learning, the Autism Diagnostic Observation Schedule (ADOS), the Autism Diagnostic Interview—Revised (ADI-R) and adaptive functioning on the Vineland Adaptive Behavior Scales. Around 11% of high-risk siblings had mild-to-moderate levels of developmental delay, a rate higher than the low-risk controls. The groups did not differ in the proportion of toddlers with mild-to-moderate language delay. Thirty percent of high-risk siblings had elevated scores on the ADOS, double the rate seen in the low-risk controls. High-risk siblings also had higher parent reported levels of ASD symptoms on the ADI-R and lower adaptive functioning on the Vineland. Males were more likely to show higher levels of ASD symptoms and lower levels of developmental ability and adaptive behavior than females across most measures but not mild-to-moderate language delay. Lower maternal education was associated with lower developmental and adaptive behavior outcomes. These findings are evidence for early emerging characteristics related to the “broader autism phenotype” (BAP) previously described in older family members of individuals with ASD. There is a need for ongoing clinical monitoring of high-risk siblings who do not have an ASD by age 3 years, as well as continued follow-up into school age to determine their developmental and behavioral outcomes. Autism Res 2016. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

    5. Category structure and processing in 6-year-old children with autism

      Allison Bean Ellawadi, Deborah Fein and Letitia R. Naigles

      Version of Record online: 12 JUL 2016 | DOI: 10.1002/aur.1652

      Scientific Abstract

      This study investigated the categorization abilities of 6-year-old children with autism spectrum disorders (ASD) as compared to their peers with typical development (TD) using a category verification task. We examined the impact of stimulus typicality on multiple aspects of real-time performance, including accuracy, reaction time, and performance stability. Both groups were more accurate in identifying typical category members than atypical ones; however, only the ASD group's accuracy was affected by item ordering, indicating less stable performance. Furthermore, category structure was predicted by concurrent language levels in the TD group but by concurrent nonverbal IQ in the ASD group; these latter two findings suggest that children with ASD process categories differently than their peers with TD. Autism Res 2016. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

    6. Voice identity processing in autism spectrum disorder

      Stefanie Schelinski, Claudia Roswandowitz and Katharina von Kriegstein

      Version of Record online: 12 JUL 2016 | DOI: 10.1002/aur.1639

    7. Children with autism spectrum disorder have reduced otoacoustic emissions at the 1 kHz mid-frequency region

      Loisa Bennetto, Jessica M. Keith, Paul D. Allen and Anne E. Luebke

      Version of Record online: 12 JUL 2016 | DOI: 10.1002/aur.1663

    8. Threatening faces fail to guide attention for adults with autistic-like traits

      Michael C. W. English, Murray T. Maybery and Troy A. W. Visser

      Version of Record online: 7 JUL 2016 | DOI: 10.1002/aur.1658

    9. Intact mirror mechanisms for automatic facial emotions in children and adolescents with autism spectrum disorder

      Martin Schulte-Rüther, Ellen Otte, Kübra Adigüzel, Christine Firk, Beate Herpertz-Dahlmann, Iring Koch and Kerstin Konrad

      Version of Record online: 28 JUN 2016 | DOI: 10.1002/aur.1654

  5. Commentary

    1. You have full text access to this OnlineOpen article
      Commentary – Autism Spectrum Disorder: Spectrum or Cluster?

      John R. Pruett Jr. and Daniel J. Povinelli

      Version of Record online: 22 JUN 2016 | DOI: 10.1002/aur.1650

  6. Research Articles

    1. You have full text access to this OnlineOpen article
      The Autism-Spectrum Quotient in Siblings of People With Autism

      Emily Ruzich, Carrie Allison, Paula Smith, Howard Ring, Bonnie Auyeung and Simon Baron-Cohen

      Version of Record online: 22 JUN 2016 | DOI: 10.1002/aur.1651

    2. Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder

      Bradley J. Ferguson, Sarah Marler, Lily L. Altstein, Evon Batey Lee, Jill Akers, Kristin Sohl, Aaron McLaughlin, Kaitlyn Hartnett, Briana Kille, Micah Mazurek, Eric A. Macklin, Erin McDonnell, Mariah Barstow, Margaret L. Bauman, Kara Gross Margolis, Jeremy Veenstra-VanderWeele and David Q. Beversdorf

      Version of Record online: 20 JUN 2016 | DOI: 10.1002/aur.1646

    3. Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case–control study

      Rezvan Noroozi, Mohammad Taheri, Abolfazl Movafagh, Reza Mirfakhraie, Ghasem Solgi, Arezou Sayad, Mehrdokht Mazdeh and Hossein Darvish

      Version of Record online: 17 JUN 2016 | DOI: 10.1002/aur.1640

    4. Autism-specific maternal anti-fetal brain autoantibodies are associated with metabolic conditions

      Paula Krakowiak, Cheryl K. Walker, Daniel Tancredi, Irva Hertz-Picciotto and Judy Van de Water

      Version of Record online: 17 JUN 2016 | DOI: 10.1002/aur.1657

    5. Linkage between pain sensitivity and empathic response in adolescents with autism spectrum conditions and conduct disorder symptoms

      Chenyi Chen, An-Yi Hung, Yang-Teng Fan, Shuai Tan, Hua Hong and Yawei Cheng

      Version of Record online: 16 JUN 2016 | DOI: 10.1002/aur.1653

    6. The autism symptom interview, school-age: A brief telephone interview to identify autism spectrum disorders in 5-to-12-year-old children

      Somer L. Bishop, Marisela Huerta, Katherine Gotham, Karoline Alexandra Havdahl, Andrew Pickles, Amie Duncan, Vanessa Hus Bal, Lisa Croen and Catherine Lord

      Version of Record online: 10 JUN 2016 | DOI: 10.1002/aur.1645

    7. Persistence of megalencephaly in a subgroup of young boys with autism spectrum disorder

      Lauren E. Libero, Christine W. Nordahl, Deana D. Li, Emilio Ferrer, Sally J. Rogers and David G. Amaral

      Version of Record online: 8 JUN 2016 | DOI: 10.1002/aur.1643

    8. A sexually dichotomous, autistic-like phenotype is induced by Group B Streptococcus maternofetal immune activation

      Marie-Julie Allard, Julie D. Bergeron, Moogeh Baharnoori, Lalit K. Srivastava, Louis-Charles Fortier, Claire Poyart and Guillaume Sébire

      Version of Record online: 25 MAY 2016 | DOI: 10.1002/aur.1647

    9. Prevalence and associated features of autism spectrum disorder in extremely low gestational age newborns at age 10 years

      Robert M. Joseph, Thomas M. O'Shea, Elizabeth N. Allred, Tim Heeren, Deborah Hirtz, Nigel Paneth, Alan Leviton and Karl C. K. Kuban

      Version of Record online: 25 MAY 2016 | DOI: 10.1002/aur.1644

    10. Autism-relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons

      Amy E. Clipperton-Allen, Youjun Chen and Damon T. Page

      Version of Record online: 25 MAY 2016 | DOI: 10.1002/aur.1641

    11. Vestibulo-ocular reflex function in children with high-functioning autism spectrum disorders

      Tana B. Carson, Bradley J. Wilkes, Kunal Patel, Jill L. Pineda, Ji H. Ko, Karl M. Newell, James W. Bodfish, Michael C. Schubert, Krestin Radonovich, Keith D. White and Mark H. Lewis

      Version of Record online: 25 MAY 2016 | DOI: 10.1002/aur.1642

    12. Impaired downregulation of visual cortex during auditory processing is associated with autism symptomatology in children and adolescents with autism spectrum disorder

      R. Joanne Jao Keehn, Sandra S. Sanchez, Claire R. Stewart, Weiqi Zhao, Emily L. Grenesko-Stevens, Brandon Keehn and Ralph-Axel Müller

      Version of Record online: 20 MAY 2016 | DOI: 10.1002/aur.1636

    13. Elevated levels of tissue plasminogen activator and E-selectin in male children with autism spectrum disorder

      Şeref Şimşek, İhsan Çetin, Abdullah Çim and Savaş Kaya

      Version of Record online: 19 MAY 2016 | DOI: 10.1002/aur.1638

    14. Atypical rapid audio-visual temporal recalibration in autism spectrum disorders

      Jean-Paul Noel, Matthew A. De Niear, Ryan Stevenson, David Alais and Mark T. Wallace

      Version of Record online: 9 MAY 2016 | DOI: 10.1002/aur.1633

    15. Personal space regulation in childhood autism: Effects of social interaction and person's perspective

      Michela Candini, Virginia Giuberti, Alessandra Manattini, Serenella Grittani, Giuseppe di Pellegrino and Francesca Frassinetti

      Version of Record online: 9 MAY 2016 | DOI: 10.1002/aur.1637

    16. Sensory subtypes and associated outcomes in children with autism spectrum disorders

      Karla K. Ausderau, John Sideris, Lauren M. Little, Melissa Furlong, John C. Bulluck and Grace T. Baranek

      Version of Record online: 2 MAY 2016 | DOI: 10.1002/aur.1626

    17. Discourse comprehension in autism spectrum disorder: Effects of working memory load and common ground

      Jillian M. Schuh, Inge-Marie Eigsti and Daniel Mirman

      Version of Record online: 19 APR 2016 | DOI: 10.1002/aur.1632

  7. Review Articles

  8. Research Articles

    1. Exploring ‘The autisms’ at a cognitive level

      Cathriona Cantio, Jens Richardt Møllegaard Jepsen, Gitte Falcher Madsen, Niels Bilenberg and Sarah J. White

      Version of Record online: 19 APR 2016 | DOI: 10.1002/aur.1630

    2. Maternal serotonin transporter genotype affects risk for ASD with exposure to prenatal stress

      Patrick M. Hecht, Melissa Hudson, Susan L. Connors, Michael R. Tilley, Xudong Liu and David Q. Beversdorf

      Version of Record online: 19 APR 2016 | DOI: 10.1002/aur.1629

  9. Commentary

    1. Toward an interdisciplinary approach to understanding sensory function in autism spectrum disorder

      Carissa J. Cascio, Tiffany Woynaroski, Grace T. Baranek and Mark T. Wallace

      Version of Record online: 19 APR 2016 | DOI: 10.1002/aur.1612

  10. Literature Review

  11. Research Articles

    1. You have full text access to this OnlineOpen article
      Screening for co-occurring conditions in adults with autism spectrum disorder using the strengths and difficulties questionnaire: A pilot study

      James Findon, Tim Cadman, Catherine S. Stewart, Emma Woodhouse, Hanna Eklund, Hannah Hayward, Daniel De Le Harpe Golden, Eddie Chaplin, Karen Glaser, Emily Simonoff, Declan Murphy, Patrick F. Bolton and Fiona S. McEwen

      Version of Record online: 28 MAR 2016 | DOI: 10.1002/aur.1625

    2. Atypical effective connectivity of thalamo-cortical circuits in autism spectrum disorder

      Heng Chen, Lucina Q. Uddin, Youxue Zhang, Xujun Duan and Huafu Chen

      Version of Record online: 22 MAR 2016 | DOI: 10.1002/aur.1614

    3. Cerebellar gray matter differentiates children with early language delay in autism

      Anila M. D'Mello, Dorothea M. Moore, Deana Crocetti, Stewart H. Mostofsky and Catherine J. Stoodley

      Version of Record online: 22 MAR 2016 | DOI: 10.1002/aur.1622

    4. Reduced goal-directed action control in autism spectrum disorder

      Gail A. Alvares, Bernard W. Balleine, Lisa Whittle and Adam J. Guastella

      Version of Record online: 21 MAR 2016 | DOI: 10.1002/aur.1613

    5. Dopaminergic variants in siblings at high risk for autism: Associations with initiating joint attention

      Devon N. Gangi, Daniel S. Messinger, Eden R. Martin and Michael L. Cuccaro

      Version of Record online: 15 MAR 2016 | DOI: 10.1002/aur.1623

    6. Aging and autism spectrum disorder: Evidence from the broad autism phenotype

      Gregory L. Wallace, Jessica Budgett and Rebecca A. Charlton

      Version of Record online: 11 MAR 2016 | DOI: 10.1002/aur.1620

    7. Relations between language and cognition in native-signing children with autism spectrum disorder

      Aaron Shield, Jennie Pyers, Amber Martin and Helen Tager-Flusberg

      Version of Record online: 3 MAR 2016 | DOI: 10.1002/aur.1621

    8. Executive function predicts the development of play skills for verbal preschoolers with autism spectrum disorders

      Susan Faja, Geraldine Dawson, Katherine Sullivan, Andrew N. Meltzoff, Annette Estes and Raphael Bernier

      Version of Record online: 18 FEB 2016 | DOI: 10.1002/aur.1608

    9. Development of the anxiety scale for children with autism spectrum disorder (ASC-ASD)

      Jacqui Rodgers, Sarah Wigham, Helen McConachie, Mark Freeston, Emma Honey and Jeremy R. Parr

      Version of Record online: 17 FEB 2016 | DOI: 10.1002/aur.1603

    10. Maternal metabolic risk factors for autism spectrum disorder—An analysis of electronic medical records and linked birth data

      Natalia Connolly, Julia Anixt, Patty Manning, Daniel Ping-I Lin, Keith A. Marsolo and Katherine Bowers

      Version of Record online: 29 JAN 2016 | DOI: 10.1002/aur.1586

    11. Communication growth in minimally verbal children with ASD: The importance of interaction

      Charlotte DiStefano, Wendy Shih, Ann Kaiser, Rebecca Landa and Connie Kasari

      Version of Record online: 29 JAN 2016 | DOI: 10.1002/aur.1594

    12. Intact recognition, but attenuated adaptation, for biological motion in youth with autism spectrum disorder

      Jeroen J. A. van Boxtel, Mirella Dapretto and Hongjing Lu

      Version of Record online: 25 JAN 2016 | DOI: 10.1002/aur.1595

    13. White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder: A voxel-based morphometry study

      Ryuzo Hanaie, Ikuko Mohri, Kuriko Kagitani-Shimono, Masaya Tachibana, Junko Matsuzaki, Ikuko Hirata, Fumiyo Nagatani, Yoshiyuki Watanabe, Norihiko Fujita and Masako Taniike

      Version of Record online: 25 JAN 2016 | DOI: 10.1002/aur.1605

    14. Atypical development of the central auditory system in young children with Autism spectrum disorder

      Yuko Yoshimura, Mitsuru Kikuchi, Hirotoshi Hiraishi, Chiaki Hasegawa, Tetsuya Takahashi, Gerard B. Remijn, Manabu Oi, Toshio Munesue, Haruhiro Higashida, Yoshio Minabe and Haruyuki Kojima

      Version of Record online: 25 JAN 2016 | DOI: 10.1002/aur.1604

    15. Uh and um in children with autism spectrum disorders or language impairment

      Kyle Gorman, Lindsay Olson, Alison Presmanes Hill, Rebecca Lunsford, Peter A. Heeman and Jan P. H. van Santen

      Version of Record online: 22 JAN 2016 | DOI: 10.1002/aur.1578

    16. Meta-analysis and association of two common polymorphisms of the human oxytocin receptor gene in autism spectrum disorder

      Thorsten M. Kranz, Marnie Kopp, Regina Waltes, Michael Sachse, Eftichia Duketis, Tomasz A. Jarczok, Franziska Degenhardt, Katharina Görgen, Jobst Meyer, Christine M. Freitag and Andreas G. Chiocchetti

      Version of Record online: 20 JAN 2016 | DOI: 10.1002/aur.1597

    17. A selective impairment in extracting fearful information from another's eyes in Autism

      Yongning Song, Yuji Hakoda and Biao Sang

      Version of Record online: 18 JAN 2016 | DOI: 10.1002/aur.1583

  12. Short Reports

    1. Sensory subtypes and anxiety in older children and adolescents with autism spectrum disorder

      Mirko Uljarević, Alison Lane, Amanda Kelly and Susan Leekam

      Version of Record online: 13 JAN 2016 | DOI: 10.1002/aur.1602

  13. Research Articles

    1. Hemispheric differences in language processing in autism spectrum disorders: A meta-analysis of neuroimaging studies

      Abbey J. Herringshaw, Carla J. Ammons, Thomas P. DeRamus and Rajesh K. Kana

      Version of Record online: 11 JAN 2016 | DOI: 10.1002/aur.1599

    2. You have full text access to this OnlineOpen article
      Functioning and disability in autism spectrum disorder: A worldwide survey of experts

      Elles de Schipper, Soheil Mahdi, Petrus de Vries, Mats Granlund, Martin Holtmann, Sunil Karande, Omar Almodayfer, Cory Shulman, Bruce Tonge, Virginia V.C.N. Wong, Lonnie Zwaigenbaum and Sven Bölte

      Version of Record online: 8 JAN 2016 | DOI: 10.1002/aur.1592

    3. Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid-induced autism

      Yuta Hara, Yukio Ago, Atsuki Taruta, Keisuke Katashiba, Shigeru Hasebe, Erika Takano, Yusuke Onaka, Hitoshi Hashimoto, Toshio Matsuda and Kazuhiro Takuma

      Version of Record online: 30 DEC 2015 | DOI: 10.1002/aur.1596

    4. You have full text access to this OnlineOpen article
    5. You have full text access to this OnlineOpen article
  14. Review Articles

  15. Research Articles

    1. Using the brief observation of social communication change (BOSCC) to measure autism-specific development

      Janina Kitzerow, Karoline Teufel, Christian Wilker and Christine M. Freitag

      Version of Record online: 8 DEC 2015 | DOI: 10.1002/aur.1588

    2. Looking, seeing and believing in autism: Eye movements reveal how subtle cognitive processing differences impact in the social domain

      Valerie Benson, Monica S. Castelhano, Philippa L. Howard, Nida Latif and Keith Rayner

      Version of Record online: 28 NOV 2015 | DOI: 10.1002/aur.1580

    3. The developmental trajectory of contrast sensitivity in autism spectrum disorder

      Jacalyn Guy, Laurent Mottron, Claude Berthiaume and Armando Bertone

      Version of Record online: 27 NOV 2015 | DOI: 10.1002/aur.1579

  16. Short Reports

    1. Semantic mapping reveals distinct patterns in descriptions of social relations in adults with autism spectrum disorder

      Sean X. Luo, Jacqueline A. Shinall, Bradley S. Peterson and Andrew J. Gerber

      Version of Record online: 27 NOV 2015 | DOI: 10.1002/aur.1581

  17. Research Articles

    1. The sensitivity and specificity of the social communication questionnaire for autism spectrum with respect to age

      Lucy Barnard-Brak, Adam Brewer, Steven Chesnut, David Richman and Anna Marie Schaeffer

      Version of Record online: 26 NOV 2015 | DOI: 10.1002/aur.1584

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