International Journal for Numerical Methods in Biomedical Engineering

Cover image for Vol. 31 Issue 3

Edited By: Perumal Nithiarasu, Rainald Löhner, Guowei Wei

Impact Factor: 1.542

ISI Journal Citation Reports © Ranking: 2013: 23/52 (Mathematical & Computational Biology); 23/95 (Mathematics Interdisciplinary Applications); 39/76 (Engineering Biomedical)

Online ISSN: 2040-7947

Associated Title(s): International Journal for Numerical Methods in Engineering, International Journal for Numerical Methods in Fluids, International Journal of Numerical Modelling: Electronic Networks, Devices and Fields, Numerical Linear Algebra with Applications

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Recently Published Articles

  1. Finite element simulation of the insertion of guidewires during an EVAR procedure: example of a complex patient case, a first step toward patient-specific parameterized models

    Juliette Gindre, Aline Bel-Brunon, Adrien Kaladji, Aurélien Duménil, Michel Rochette, Antoine Lucas, Pascal Haigron and Alain Combescure

    Accepted manuscript online: 27 MAR 2015 10:19AM EST | DOI: 10.1002/cnm.2716

  2. Computational model of collagen turnover in carotid arteries during hypertension

    P. Sáez, E. Peña, J. M. Tarbell and M. A. Martínez

    Article first published online: 15 MAR 2015 | DOI: 10.1002/cnm.2705

    Thumbnail image of graphical abstract

    We studied the collagen turnover in the arterial tissue of hypertensive patients through a coupled computational mechano-chemical finite element model in three stages: (1) the smooth muscle cells synthesize different biological substances because of the overstretching during hypertension; (2) mass transport occurs along the arterial wall; and (3) the turnover of collagen takes place based on the amount of these substances. The final results show the well-known stiffening of the arterial wall due to the increase in the collagen content.

  3. Tracing vocal-fold vibrations using level-set segmentation method

    Tailong Shi, Hyun June Kim, Thomas Murry, Peak Woo and Yuling Yan

    Accepted manuscript online: 13 MAR 2015 10:26AM EST | DOI: 10.1002/cnm.2715

  4. A phenomenological particle-based platelet model for simulating filopodia formation during early activation

    Seetha Pothapragada, Peng Zhang, Jawaad Sheriff, Mark Livelli, Marvin J. Slepian, Yuefan Deng and Danny Bluestein

    Article first published online: 13 MAR 2015 | DOI: 10.1002/cnm.2702

    Thumbnail image of graphical abstract

    We present a three-dimensional particle-based model of a platelet with key subcellular elements. It is designed to simulate quiescent platelet shape before activation and dynamic filopodia formation upon activation. The function that maps the model parameters to observed geometric measurements in flow-induced activated platelets was established by analyzing the numerical trends, enabling the use of formulae for simulating filopodia of varied lengths and thicknesses. The model, along with experimental investigation, establishes a novel dynamic framework for exploring the underlying mechanism of filopodia formation and their quantitative contribution to platelet shape change.

  5. Rational macromodeling of 1D blood flow in the human cardiovascular system

    Francesco Ferranti, Vincenzopio Tamburrelli and Giulio Antonini

    Article first published online: 13 MAR 2015 | DOI: 10.1002/cnm.2707

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    We present a novel rational macromodeling approach for the description of 1D blood flow in the human cardiovascular system. The rational form of the proposed cardiovascular model leads to a state-space or electrical circuit model suitable for time-domain analysis. The stability and passivity properties of the cardiovascular model are discussed to guarantee stable time-domain simulations, and frequency and time-domain results validate the proposed macromodeling approach.

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