International Journal for Numerical Methods in Biomedical Engineering

Cover image for Vol. 31 Issue 6

Edited By: Perumal Nithiarasu, Rainald Löhner, Guowei Wei

Impact Factor: 2.052

ISI Journal Citation Reports © Ranking: 2014: 16/56 (Mathematical & Computational Biology); 18/99 (Mathematics Interdisciplinary Applications); 30/76 (Engineering Biomedical)

Online ISSN: 2040-7947

Associated Title(s): International Journal for Numerical Methods in Engineering, International Journal for Numerical Methods in Fluids, International Journal of Numerical Modelling: Electronic Networks, Devices and Fields, Numerical Linear Algebra with Applications

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  1. A benchmark study of numerical schemes for one-dimensional arterial blood flow modelling

    Etienne Boileau, Perumal Nithiarasu, Pablo J. Blanco, Lucas O. Müller, Fredrik Eikeland Fossan, Leif Rune Hellevik, Wouter P. Donders, Wouter Huberts, Marie Willemet and Jordi Alastruey

    Article first published online: 3 JUL 2015 | DOI: 10.1002/cnm.2732

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    We present for the first time a detailed comparison of six numerical schemes for 1D blood flow modelling, made in a series of six benchmark cases and supported by graphical and tabulated results. All the information is made publicly available to support the development of 1D models and numerical schemes, providing a comprehensive reference data set to the interested reader.

  2. Dynamic flow characteristics in normal and asthmatic lungs

    Minsuok Kim, Rafel Bordas, Wim Vos, Ruth A. Hartley, Chris E. Brightling, David Kay, Vicente Grau and Kelly S. Burrowes

    Article first published online: 25 JUN 2015 | DOI: 10.1002/cnm.2730

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    We modeled dynamic pressure and flow changes in normal, virtually constricted and asthmatic airway geometries using a fully coupled model of airway dynamics and an airway network system. The asthmatic airway model showed elevated ventilation heterogeneity and temporal flow disturbance, reverse flow, which ultimately affected total lung resistance. This study suggests that dynamic flow characteristics may be an important factor for asthmatic lung function.

  3. A joint-space numerical model of metabolic energy expenditure for human multibody dynamic system

    Joo H. Kim and Dustyn Roberts

    Article first published online: 24 JUN 2015 | DOI: 10.1002/cnm.2721

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    In this study, a joint-space numerical model of metabolic energy expenditure (MEE) is derived by integrating the laws of thermodynamics and principles of multibody system dynamics, and a constrained multi-objective optimization algorithm is established to estimate the model parameters. The joint-space parameters estimated directly from active subjects provide reliable MEE estimates while avoiding the limitations in experimental measurements (phase delays, steady-state and task restrictions) or muscle-based models (excessive degrees of freedom, wrapping, and in vitro parameters). The model enables real-time calculations of instantaneous MEE rate as a function of time for complex non-periodic tasks.

  4. Prostate contours delineation using interactive directional active contours model and parametric shape prior model

    Foued Derraz, Gérard Forzy, Arnaud Delebarre, Abdelmalik Taleb-Ahmed, Mourad Oussalah, Laurent Peyrodie and Sebastien Verclytte

    Article first published online: 24 JUN 2015 | DOI: 10.1002/cnm.2726

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    We proposed a new bi-stage contours delineation algorithm based on directional active contours (DAC) incorporating both statistical and parametric shape prior model. We exploit the global aspects of contour delineation problem by incorporating a user feedback in contours delineation process where it is shown that only a small amount of user input can sometimes resolve ambiguous scenarios raised by DAC. In addition, a cost functional is designed to incorporate additional user feedback interaction.

  5. A poroelastic model coupled to a fluid network with applications in lung modelling

    Lorenz Berger, Rafel Bordas, Kelly Burrowes, Vicente Grau, Simon Tavener and David Kay

    Accepted manuscript online: 23 JUN 2015 03:04AM EST | DOI: 10.1002/cnm.2731