International Journal for Numerical Methods in Biomedical Engineering

Cover image for Vol. 31 Issue 5

Edited By: Perumal Nithiarasu, Rainald Löhner, Guowei Wei

Impact Factor: 1.542

ISI Journal Citation Reports © Ranking: 2013: 23/52 (Mathematical & Computational Biology); 23/95 (Mathematics Interdisciplinary Applications); 39/76 (Engineering Biomedical)

Online ISSN: 2040-7947

Associated Title(s): International Journal for Numerical Methods in Engineering, International Journal for Numerical Methods in Fluids, International Journal of Numerical Modelling: Electronic Networks, Devices and Fields, Numerical Linear Algebra with Applications

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Recently Published Articles

  1. Prostate contours delineation using interactive directional active contours model and parametric shape prior model

    Foued Derraz, Gérard Forzy, Arnaud Delebarre, Abdelmalik Taleb-Ahmed, Mourad Oussalah, Laurent Peyrodie and Sebastien Verclytte

    Accepted manuscript online: 24 MAY 2015 11:55PM EST | DOI: 10.1002/cnm.2726

  2. A polynomial hyperelastic model for the mixture of fat and glandular tissue in female breast

    Jose L. Calvo-Gallego, Javier Martínez-Reina and Jaime Domínguez

    Article first published online: 24 MAY 2015 | DOI: 10.1002/cnm.2723

    Thumbnail image of graphical abstract

    A mechanical model is proposed for the mixture of tissues in the breast as a function of the fat content. A multiscale modelling approach was applied in a finite element model of a representative volume element(RVE) of tissue. The RVE was subjected to several load cases from which the constitutive equations of the homogenized tissue were fitted. The results confirm that the fat volume ratio is a key factor, but the spatial distribution of fat is not so important.

  3. Mixed–element Octree: a meshing technique towards fast and real–time simulations in biomedical applications

    Claudio Lobos and Eugenio González

    Accepted manuscript online: 22 MAY 2015 08:31AM EST | DOI: 10.1002/cnm.2725

  4. Patient-specific anisotropic model of human trunk based on MR data

    O. Courchesne, F. Guibault, Stefan Parent and Farida Cheriet

    Accepted manuscript online: 15 MAY 2015 09:12AM EST | DOI: 10.1002/cnm.2724

  5. Persistent topology for cryo-EM data analysis

    Kelin Xia and Guo-Wei Wei

    Article first published online: 6 MAY 2015 | DOI: 10.1002/cnm.2719

    Thumbnail image of graphical abstract

    Cryo-electron microscopy (cryo-EM) is a key technology for the structure determination of large biomolecules. However, it suffers from low signal-to-noise ratio and low resolution. We introduce persistent homology, a new branch of algebraic topology, to guild the noise removal with Laplace– Beltrami flow, which is found to preserve the intrinsic topological fingerprints of cryo-EM structures and diminish the topological signature of noise. Additionally, as shown in the figure, the conventional structure determination of cryo-EM data is an ill-posed inverse problem: two fitted structures have the same good correlation coefficients. We resolve this problem by analyzing the topology fingerprints, which gives rise to a unique solution.