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Clinical Liver Disease

Cover image for Vol. 5 Issue 6

Edited By: Michael Lucey, MD

Online ISSN: 2046-2484

Associated Title(s): Hepatology, Liver Transplantation

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Liver and the Microbiome

Guest Edited by Eamonn M.M. Quigley, MD, FRCP, FACP, FACG, FRCPI


Host-Microbiome Interactions in Health and Disease
Liam O’Mahony, PhD
Microbes and metabolites
In the latest installment in our series on the liver and the microbiome, learn about the basics of mucosal immunology, mechanisms for microbiome-host interactions, and implications of disturbed host-microbe interactions for disease states.
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More on Liver and the Microbiome:

Microbiome-Immune Interactions and Liver Disease
James H. Tabibian MD, PhD, Cyril Varghese MD, Steven P. O’Hara PhD, and Nicholas F. LaRusso MD
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The Gut Microbiome: What Do We Know?
Francisco Guarner, MD, PhD
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The Metabolic Role of the Microbiota
Wiley Barton B.Sc. Fergus Shanahan MD, Paul D. Cotter PhD, Orla O’Sullivan PhD
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Is the Gut Microbiota Disturbed in Chronic Liver Disease?
Eamonn M.M. Quigley, MD, FRCP, FACP, FACG, FRCPI
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Microbiome and Complications of Liver Disease
Jasmohan S. Bajaj, MD, MS, FACG, AGAF
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NEW in Liver Transplantation:

Guest Edited by Paul Martin, MD

Hepatitis C Treatment In Liver Transplant Setting
Adam Peyton DO and Kalyan Ram Bhamidimarri, MD, MPH
What do you know about the timing of HCV treatment? HCV treatment in the pre-liver transplant setting? Can you describe the newest agents and strategies? Read on for the answers in our the latest review on liver tranplantation.
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Renal Dysfunction in Cirrhosis
Chong Y. Parke MD, Paul Martin MD, Suphamai Bunnapradist MD
Review the current approach, management, and prevention of renal dysfunction in patients with cirrhosis.
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More on Liver Transplantation:

Update on MELD and Organ Allocation
Eric F. Martin, MD, and Christopher O’Brien, M.D., AGAF, FRCMI
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Care of the Patient With Cirrhosis
Anitha Yadav, MD, and Hugo E. Vargas, MD
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Check out what's new in CLD's sister journal, HEPATOLOGY

HEPATOLOGY Highlights



Popular in our series on New Treatments for Hepatitis C

Guest Edited by Donald M. Jensen, MD, FACP

New Therapies for Hepatitis C: Latin American Perspectives
Rafael Claudino Botero, MD, FACP, and Martin Tagle, MD
Watch the interview
Learn about the unique challenges for treating Hepatitis C in Latin America, including a detailed country by country analysis.
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Prefer to learn in Spanish? Read the article or watch an interview with Dr. Botero, todo en español!

Los Nuevos Tratamiento de Hepatitis C: Perspectivas Latinoamericanas
Read the full textWatch the author interview.

The Future in Liver Medicine

Guest Edited by Meena Bansal, MD

The Future of Hepatology: Embrace Change
Scott L. Friedman MD and Yael L. Friedman MA
Interview with Scott Friedman
If the astounding progress in hepatology over the past 35 years is any indication of the future, the next 35 years will advance in ways that may be unrecognizable by today’s standards.
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Training the Next Generation of Hepatologist: What Will They Need to Know?
Dina L. Halegoua-De Marzio MD, and Steven K. Herrine MD
With major changes in health care on the horizon, it's more important than ever to identify the skills hepatologists will need and what new challenges they will face.
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Personalized Management of Hepatocellular Carcinoma Based on Molecular Information: Future Prospects
Nicolas Goossens, MD, MSc Yujin Hoshida, MD, PhD
Read an overview of the evolving challenges in HCC in relation to the epidemic of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis, and the everexpanding inventories of molecular agents and genomics technologies that have enabled exploration of more personalized management of the patients.
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Increasing Impact of Drug-Induced Liver Injury
Paul H. Hayashi, MD, MPH and Naga P. Chalasani MD
Idiosyncratic drug-induced liver injury (DILI) represents one of the most challenging consultations for a hepatologist. Population incidence is likely on the rise, and for certain medications, the risk may be higher than previously recognized.
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Future Watch: Evolving Trends in the Management of Nonalcoholic Steatohepatitis
Arun J. Sanyal, MBBS, MD
Nonalcoholic steatohepatitis (NASH) has emerged as the leading etiology of chronic liver disease in the United States and is a growing problem in virtually all parts of the world.
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Non-Cirrhotic Portal Hypertension


Guest Edited by Theo Heller, MD, Ohad Etzion, MD, and Christopher Koh, MD

Surgical Management of Noncirrhotic Portal Hypertension
Josep Marti, MD, PhD, Ganesh Gunasekaran, MD, FACS, Kishore Iyer, MD, Myron Schwartz, MD
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Noncirrhotic Portal Hypertension in the Pediatric Population
Amy G. Feldman, MD, Ronald J. Sokol, MD
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Idiopathic Noncirrhotic Portal Hypertension: What Is It?
Guadalupe Garcia-Tsao, MD
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Noncirrhotic Portal Hypertension: Pathology and Nomenclature
David E. Kleiner, MD, PhD
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