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Sexual Medicine

Articles are published under the terms of the Creative Commons License as stated in the final article.

Cover image for Vol. 2 Issue 2

Online ISSN: 2050-1161

Associated Title(s): Sexual Medicine Reviews, The Journal of Sexual Medicine

Author Guidelines

1. Submit or confirm your submission at
2. We will send you an email confirmation of your submission details.
3. After review and acceptance, you will be prompted to sign the Open Access Agreement form. Payment of the article publication charge will be required. You can then track the progress of your article through Wiley Author Services.
4. You will receive notification that your proof is ready for review, and be able to make corrections to your article.
5. Your article will publish on Wiley Online Library. If you have previously signed up for alerts through Wiley’s Author Services, you will be sent an email when your article is published online.

If your paper is accepted, the author whom you identify as being the corresponding author for the paper will be presented with the option to sign an open access agreement (on behalf of all co-authors) to make the article available under the terms of either the Creative Commons Attribution Non-Commercial (CC BY-NC) license or the Creative Commons Attribution-Non-Commercial-NoDerivs License (CC-BY-NC-ND). RCUK or Wellcome trust funded authors will be directed to sign the open access agreement under the terms of the Creative Commons Attribution license (CC-BY) in order to be funder compliant. For more information on the terms and conditions of these licenses please visit:

Alan W. Shindel, MD
Department of Urology
University of California, Davis
4860 Y Street, Suite 3500
Sacramento, CA 95817 U.S.A.

Address correspondence to the Editorial Office:
Jason Roberts, PhD
Managing Editor, Sexual Medicine (SM)
36 Old Mill Lane
Plymouth, MA 02360, USA
Fax: ( 1) 508-242-1184
Phone: ( 1) 617-417-6269

Sexual Medicine requires that authors submit electronically via the ScholarOne Manuscripts online submission site at Complete, detailed instructions on uploading your manuscript are available detailed below.

Please note that if you are an author or reviewer for The Journal of Sexual Medicine, you automatically have an account with Sexual Medicine and you should use the same login information for submission to a journal that you use for the other journal. Any major word processor software may be used, and both DOS-based and Macintosh operating systems are acceptable.

Sexual Medicine publishes several types of manuscripts under the umbrella of full-length articles. A brief description of each type follows:

  • Original Research

  • Reports and Brief Reports

  • Reviews

  • Methods Papers

  • Editorials

Original Research
Sexual Medicine will consider all types of original clinical and basic research papers, including studies conducted with human subjects and experimental models, as well as high-quality clinical, epidemiological, and healthcare policy papers related to sexual function and dysfunction. Sexual Medicine particularly serves as a venue for topics of regional or specialty interest although any manuscript dealing with sexuality research will be considered. Specific interest is in the following areas of content: Education, Epidemiology, Basic Science, Psychology, Outcomes Assessment, Anatomy/Physiology, Intersex and Gender Identity Disorders, Sexual Orientation, Ejaculatory Disorders, Women’s Sexual Health, Men’s Sexual Health, Couple’s Sexual Dysfunctions, Pharmacotherapy, Peyronie’s Disease, Pain, Erectile Dysfunction, Premature Ejaculation, Hypoactive Sexual Desire Disorder, Dyspareunia, Pharmacotherapy for Sexual Dysfunction, Surgical Management of Sexual Dysfunction, Endocrinology, Oncology.

As a general guideline, manuscripts should be 3,000 words in length; more extensive manuscripts will be considered and judged on merit; however, authors are urged to be as concise as possible. All manuscripts must include an abstract, a maximum of 7 tables and figures (total), and up to 50 references. More may be accepted if justified.

Reports usually describe one to three patients with pertinent conditions. Brief Reports are concise reports of cases, clinical experience, clinical studies, drug trials, adverse effects, or devices related to sexual medicine. Maximum length of text is 1,750 words; no more than 10 bibliographic references and one figure or table per case.

Sexual Medicine does not solicit review articles; however, well-researched and written systematic reviews with meta-analysis on the state of the art in sexuality research/clinical practice for specialty populations and/or in specific geographic regions will be considered. The text should be approximately 5,000 words, with an abstract, a maximum of 7 tables and figures (total), and up to 75 references. More references may be accepted if justified. Review articles undergo the same peer-review and editorial process as all other manuscripts submitted to the journal.

Editorials providing commentary and analysis of an article in the particular issue of the journal will be considered. Authors of the original paper will be given opportunity to respond to the editorial comment in the same issue. Editorial comments are limited to 1,000 words, with up to 7 references.

Manuscripts must be submitted in grammatically correct English, with spelling and phrasing consistent throughout the paper. Manuscripts that do not meet this standard cannot be reviewed.

English-Language Editing Services
Authors for whom English is a second language may wish to consult an English-speaking colleague or consider having their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

A manuscript is considered for review and possible publication on the condition that it is submitted solely to Sexual Medicine, and that the manuscript or a substantial portion of it is not under consideration elsewhere. In order for a manuscript to be considered for publication all named authors must agree 1) to its submission, 2) that it is not currently being considered for publication by another journal, and 3) if accepted, the paper will not subsequently be published in the same or similar form in any language without the written consent of the publisher.

Manuscript Structure
Each manuscript must contain the following structured headings:

  • Abstract

  • Introduction

  • Aims

  • Methods

  • Main Outcome Measures

  • Results

  • Conclusions

  • References

Reporting Checklists
It is strongly recommended, where appropriate, that you ensure your manuscript conforms to a reporting guideline that best fits your type of manuscript. For example, a CONSORT statement should be completed and uploaded with your manuscript for a Randomized Controlled Trial. The International Society for Sexual Medicine (ISSM) Publication Reporting Guidelines detail the appropriate checklist(s) to use per study type.

We urge you when completing your reporting checklist to take the time to ensure your manuscript meets these basic reporting needs. In doing so, you will greatly enhance your chances of publication.

Randomized Controlled Trials
Reports of Randomized Controlled Trials (RCTs) must state explicitly how the comparison groups were generated, so that readers will be able to assess the method of randomization. In the title and abstract, specify that the manuscript is a report of an RCT. Prior to submitting an RCT manuscript; authors should refer to the CONSORT checklist (Moher D, Schultz KF, Altman D, for the CONSORT Group. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA. 2001;285:1987–1991).

Clinical Trial Registry
Sexual Medicine requires that all prospective, randomized, controlled trials with patient enrollment starting on or after August 1, 2007, be registered in a public database that meets the requirements of the World Health Organization. Currently, such registries include the following:,,,, and

For more information, please refer to the guidelines at Upon submission, please provide the registration identification number and the URL for the trial’s registry in your cover letter.

Reports of Diagnostic Tests
Authors of reports of diagnostic tests are encouraged to submit the STARD flow diagram and checklist (Bossuyt PM, Reitsma JB, Bruns DF, et al. for the STARD Group. Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Clin Chem. 2003;49:1-18).

Cell Line Authentication
To ensure the highest standards of quality and accuracy, Sexual Medicine strongly encourages the authentication of cell lines used in the research submitted to the journal. Manuscripts based on research using cell lines must include a statement addressing the following points in the Methods section of the manuscript:
1. Where the cells were obtained from
2. Whether the cell lines have been tested and authenticated
3. The method by which the cells were tested

If cells were obtained directly from a cell bank that performs cell line characterizations and passaged in the user’s laboratory for fewer than 6 months after receipt or resuscitation, re-authorization is not required. In these cases, please include the method of characterization used by the cell bank. If the cell lines were obtained from an alternate source, authors must provide authentication of the origin and identity of the cells. This is best achieved by DNA (STR) profiling. The DNA profile should be cross-checked with the DNA profile of the donor tissue (in case of a new cell line) or with the DNA profile of other continuous cell lines.

Gene names and genetic profiling data: Please mark all gene names in italics. However, only the gene names should be written in italics, to distinguish them from gene products, gene segments, clusters, families, complexes, or groups. Authors should only use the official gene name as assigned by the respective gene nomenclature committee. Regarding comprehensive data sets of genetic profiling (microarray) studies, raw data must be in a publicly available database that requires MIAME format (for example, “GEO” or “Array Express”) upon submission of a paper. Nucleotide sequence data can be submitted in electronic form to any of the three major collaborative databases: DDBJ, EMBL or GenBank. It is only necessary to submit to one database as data are exchanged between DDBJ, EMBL and GenBank on a daily basis. The suggested wording for referring to accession-number information is: ‘These sequence data have been submitted to the DDBJ/EMBL/GenBank databases under accession number U12345.’

Statistical Guidelines
All submitted manuscripts containing data analyses will be evaluated for the integrity of the statistical methods as well as a sufficient description of the methodological approach. This will entail evaluation of the study design, statistical analysis and presentation and interpretation of study results. As a general guideline, readers of the manuscript should be able to replicate the analysis with the same data based on the description given in the Methods section. Authors are encouraged to carefully select language in the Discussion that is appropriate given the study design and refrain from causal inferences from observational (nonrandomized) studies.

Authors should also be explicit about the limitations of the study. Failure to disclose important limitations upon submission will be viewed with greater scrutiny than those clearly discussed. Key elements which should be consistent for all submitted manuscripts include the following:

  • Report the sample size n for each study and each analysis

  • Describe the power analysis to justify the sample size if appropriate

  • Identify all statistical methods and verify the assumptions for all statistical tests

  • Provide alpha (the probability of a Type I error) for all statistical tests

  • Specify whether tests are one- or two-sided

  • Report the descriptive statistics (n, mean, median, and standard deviation) for all continuous variables

  • Report n and the sample proportion for binary variables

  • Adequately explain complex statistical procedures such a multivariate logistic regression and the Cox proportional hazards regression model and verify the assumptions of each such procedure

  • Report the actual P-values and explain what is meant by statistical significance

  • Discuss and describe adjustments for multiple testing

All manuscripts must conform to the policies outlined in the ISSM Publication Guidelines.

Informed Consent
Sexual Medicine requires that all appropriate steps be taken in obtaining informed consent of any and all human and/or experimental animal subjects participating in the research comprising the manuscript submitted for review and possible publication. A statement indicating that the protocol and procedures employed were reviewed and approved by the appropriate institutional review committee must be included in the Methods section of the manuscript. For research involving recombinant DNA, containment facilities and guidelines should conform to those of the National Institutes of Health or corresponding institutions. For those investigators who do not have formal ethics review committees, the principles outlined in the Helsinki Declaration of 1975, as revised in 1983, should be followed. A statement is required with any report of investigations involving human subjects confirming that informed consent was obtained from the subject(s) and/or guardian(s). It should be stated clearly in the manuscript that informed consent was obtained.

Photographs with Identifiable Patients
In photographs, sonograms, CT scans, etc., the physical identification of a patient should be masked whenever possible. If a patient is identifiable, written permission to use the photograph must be obtained from the patient or guardian and sent to the Sexual Medicine Editorial Office upon manuscript submission. Clearly state in the manuscript that informed consent has been obtained.

Disclosure Statement
Sexual Medicine requires that all authors disclose any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, which might be perceived as influencing an author's objectivity, is considered a potential source of conflict of interest. These must be disclosed when directly relevant or directly related to the work that the authors describe in their manuscript. Potential sources of conflict of interest include, but are not limited to, patent or stock ownership, membership of a company board of directors, membership of an advisory board or committee for a company, and consultancy for or receipt of speaker's fees from a company. The existence of a conflict of interest does not preclude publication in any ISSM journals. If the authors have no conflict of interest to declare, they must also state this at submission. It is the responsibility of the corresponding author to review this policy with all authors and collectively to list on the cover letter to the Editor-in-Chief, in the manuscript (under the Acknowledgements section), and in the online submission system ALL pertinent commercial and other relationships.

Authors' Professional and Ethical Responsibilities
Should possible scientific misconduct or dishonesty in research submitted for review be suspected or alleged, Sexual Medicine reserves the right to forward any submitted manuscript to the sponsoring or funding institution or to other appropriate authorities for investigation. The journal also screens manuscripts for incidents of plagiarism; please ensure that manuscripts present original data written in unique language.

Sexual Medicine requires that all authors complete an authorship statement. All persons designated as authors should qualify for authorship. Each author should have participated sufficiently in the work to take public responsibility for the content. Authorship credit should be based only on substantial contributions to Category 1: a) conception and design, b) analysis of data, and c) interpretation of data; and Category 2: a) drafting the article, or b) revising it critically for important intellectual content; and on Category 3) final approval of the version to be published. Categories 1, 2, and 3 must all be met. Participation solely in the acquisition of funding or the collection of data does not justify authorship. General supervision of the research group is not sufficient for authorship. Any part of an article critical to its main conclusions must be the responsibility of at least one author.

Editors may ask authors to describe what each contributed; this information may be published. Increasingly, multicenter trials are attributed to a corporate author. All members of the group who are named as authors, either in the authorship position below the title or in a footnote, should fully meet the above criteria for authorship. Group members who do not meet these criteria should be listed, with their permission, in the Acknowledgments or in an appendix. The order of authorship should be a joint decision of the coauthors. Because the order is assigned in different ways, its meaning cannot be inferred accurately unless it is stated by the authors. Authors may wish to explain the order of authorship in a footnote. In deciding on the order, authors should be aware that many journals limit the number of authors listed in the table of contents and that the U.S. National Library of Medicine (NLM) lists in MEDLINE only the first 24 plus the last author when there are more than 25 authors.

Drugs and Devices
Use generic drug names (or generic name followed by trade name in parentheses) may be used. Include manufacturer and their location (city and country) for drugs and devices.

Information reproduced from another source must be properly cited. The corresponding author is responsible for obtaining written permission from the appropriate authors and/or copyright holders to use previously published or copyrighted material. Signed permission statements from the copyright holder for both print and online reproduction must be sent to the Sexual Medicine Editorial Office upon manuscript submission. Permission statements also must be obtained from at least one author when citing unpublished data, in press articles, and/or personal communications.

In general, manuscripts should be prepared in accordance with “Uniform Requirements for Manuscripts Submitted to Biomedical Journals” developed by the International Committee of Medical Journal Editors (

We place few restrictions on the way in which you prepare your article, and it is not necessary to try to replicate the layout of the journal in your submission. We ask only that you consider your reviewers by supplying your manuscript in a clear, generic and readable layout, and ensure that all relevant sections are included. Our production process will take care of all aspects of formatting and style.

Please use the Manuscript Submission Checklist at the end of the Author Guidelines to ensure that the manuscript has all the information necessary for successful publication.

Abstracts must be submitted in the appropriate field without the manuscript title or factors identifying the authors or institutions. Abstracts have a 300 word limit. Abstracts must be structured to include introduction, aim, methods, main outcome measures, results and conclusions.

Below the abstract authors should provide, and identify as such, 4 to 10 key words or short phrases that will assist indexers in cross-indexing the article and may be published with the abstract. Terms from the Medical Subject Headings (MeSH) list of Index Medicus should be used; if suitable MeSH terms are not yet available for recently introduced terms, present terms may be used.

References are to be cited consecutively in the text typed after the final punctuation. References at the end of each manuscript should be listed in the order in which they are first cited in the text, typed double-spaced. The references should conform to the Index Medicus style, omitting number and day of month of issue. Punctuation is shown in the examples below. References to articles in press must state name of journal and if possible, volume and year.

For journal articles: all authors should be listed, title of article; name of journal; year; volume number; first and last page.
For books: surname and initials of all authors, title and subtitle, edition (other than first), publishing house, city, year, page as specific reference.
For chapters in books: surname and initials of all authors of chapter, title of chapter, editors, authors, or compilers of book, title of book, edition (other than first), publishing house, city, year, page

1. Jones, TH, Smith, ML, Land SW. Diagnosis and treatment of erectile dysfunction. J Urol 1986;135:922-927.
2. King, RE. Sexual dysfunction in men and women. Taylor and Francis: Philadelphia 1974, 86pp.
3. Stevens RA, Otis PN. Persistent sexual arousal syndrome. In: Johnson DA, ed. Female sexual dysfunction.. Little Brown and Company: Boston, 1976, pp 100-106.

Abbreviations, Symbols, and Nomenclature
A list of acceptable abbreviations is published in the Uniform Requirements for Manuscripts submitted to Biomedical Journals (also known as the Declaration of Vancouver). For more information, refer to: International Committee of Medical Journal Editors. Uniform requirements for manuscripts submitted to biomedical journals. Ann Intern Med 1997;126:36-47. You may contact the Editor or publisher directly with questions.

Quantitative data must be reported in the International System of Units (SI units).

Tables and Figures - House Style Guidelines
All tables and figures must be original for original research. If a table or figure has been published before, written permission must be given by the owner for its reproduction.

All tables must be cited in the text in the order that they should appear. Tables should be typed double-spaced on separate pages with number and title. Symbols for units should be confined to column headings. Tables must be supplied in an editable format. It is not acceptable to supply tables as images. You will be asked to resupply any table submitted in a non-editable format.

Authors may publish color images free of charge in Sexual Medicine. All figures must be cited in the text in the order that they should appear. Illustrations are an important medium through which to convey the meaning in your article, and there is no substitute for preparing these to the highest possible standard. Therefore, please create your illustrations carefully with reference to our graphics guidelines (see It is very difficult to improve an image that has been saved or created in an inappropriate format. We realize that not everyone has access to high-end graphics software, so the following information may help if you are having difficulty in deciding how to get the best out of the tools at your disposal.

1. Check your software options to see if you can ‘save as’ or ‘export’ using one of the robust, industry-standard formats. These are:

  • Encapsulated PostScript (EPS)

  • Tagged Image File Format (TIFF)

  • Portable Network Graphics (PNG)

  • Portable Document Format (PDF)

2. As a general rule of thumb, images that contain text and line art (graphs, charts, maps, etc.) will reproduce best if saved as EPS or PDF. If you choose this option, it is important to remember to embed fonts. This ensures that any text reproduces exactly as you intend.
3. Images that contain photographic information are best saved as TIFF or PNG, as this ensures that all data are included in the file. JPEG (Joint Photographic Experts Group) should be avoided if possible, as information is lost during compression; however, it is acceptable for purely photographic subjects if the image was generated as a JPEG from the outset (many digital cameras, for example, output only in JPEG format).
4. If you are not sure which format would be the best option, it is always best to default to EPS or PDF as these are more likely to preserve the high-quality characteristics of the original.
5. Microsoft Office. If you have generated your images in Microsoft Office software (Word, Excel, PowerPoint), or similar, it is often best simply to send us the files in their native file formats. 6. Please ensure all images are a minimum of 600 dpi.

Supporting Information
Supporting Information can be a useful way for an author to include important but ancillary information with the online version of an article. Examples of Supporting Information include additional tables, data sets, figures, movie files, audio clips, and other related nonessential multimedia files. Supporting Information should be cited within the article text, and a descriptive legend should be included. It is published as supplied by the author, and a proof is not made available prior to publication; for these reasons, authors should provide any Supporting Information in the desired final format.

For further information on recommended file types and requirements for submission, please visit:


Editorial and Peer Review Process
Sexual Medicine pursues editorial approaches that may help us avoid bias. We do our utmost to judge research objectively on its own merits and to avoid favoring research, for example, from particular institutions, countries, or regions. Sexual Medicine employs a double-blind review process in which author identities and peer reviewer identities are kept confidential from one another. Most submissions transferred to Sexual Medicine from The Journal of Sexual Medicine will be assessed using the original peer-review reports from those journals; however, the Editor-in-Chief will critically review these peer-review reports and may choose to send manuscripts out for additional double-blind review. The existence of a manuscript under review is not revealed to anyone other than the peer reviewers and editorial staff. Peer reviewers are required to maintain confidentiality about the manuscripts they review and must not divulge any information about a specific manuscript or its content to any third party without prior permission from the journal editors. All authors will be sent notification of the receipt of manuscripts and editorial decisions by e-mail. During the review process, designated contact authors can also check the status of the submitted manuscript via ScholarOne Manuscripts at

Information for Peer Reviewers
As per the guidelines issued by the World Association of Medical Editors (for further information, refer to

“Reviews will be expected to be professional, honest, courteous, prompt, and constructive. The desired major elements of a high-quality review should be as follows:
  • The reviewer should have identified and commented on major strengths and weaknesses of study design and methodology.

  • The reviewer should comment accurately and constructively upon the quality of the author's interpretation of the data, including acknowledgment of its limitations.

  • The reviewer should comment on major strengths and weaknesses of the manuscript as a written communication, independent of the design, methodology, results, and interpretation of the study.

  • The reviewer should comment on any ethical concerns raised by the study, or any possible evidence of low standards of scientific conduct.

  • The reviewer should provide the author with useful suggestions for improvement of the manuscript.

  • The reviewer's comments to the author should be constructive and professional.

  • The review should provide the editor the proper context and perspective to make a decision on acceptance (and/or revision) of the manuscript.”

Recommendations about publication are appreciated and are welcomed in the comments to the Editors. However, we kindly ask that reviewers not make such recommendations in their comments to the authors. Indeed, it is our policy to edit such comments out of any communications to authors.

Cross Check
Cross Check

CrossCheck is a multi-publisher initiative to screen published and submitted content for originality. To find out more about CrossCheck visit By submitting your manuscript to Sexual Medicine you accept that your manuscript may be screened, using the iThenticate tool, for textual similarity to other previously published works.


Soon after acceptance, you will receive an email containing your PDF proof. Once you have submitted your corrections, the production office will finalize the layout of your article for publication.

As this is an open access journal, you have free, unlimited access to your article online. However, if you wish to obtain printed reprints, these may be ordered online:

Production Questions
Please direct any questions regarding the production of your article to the Production Editor at

If you need additional help, please contact the Managing Editor at

Manuscript Submission Checklist
Please complete the following steps to ensure the correct submission of your manuscript:

• Include a title page for your manuscript that is separate from the rest of the main document (preferably uploaded as a Supplementary File Not for Review), including:
  • Full author names and the highest qualifications (PhD, MD, etc.) for all authors;

  • Institution, city and country details for each author; and,

  • Address of corresponding author (especially email address for the person to whom the proof notification is to be sent).

• Please upload the main manuscript without identifying author information, including:
  • Title page WITHOUT authors’ names or authors’ affiliations o Abstract and 4–10 keywords o Text (introduction, materials and methods, results, discussion)

  • Literature cited (see below for tips on references)

  • Tables (may be sent as a separate file if necessary)

  • Figure legends

  • Acknowledgements, including details of funding bodies with grant numbers

• Abstracts for Original Research articles must be structured as follows: Introduction, Aims, Methods, Main Outcome Measures, Results, Conclusion.
• Abstracts for Case Reports should be structured as follows: Introduction, Aims, Methods, Results, Conclusion.
• Provide a conflict of interest statement for every author.
• Please pay attention to the quality of all figures and artwork supplied (see below for requirements):

  • All charts must be in black and white or grayscale.

  • Should your figures originate in a PowerPoint presentation, please remove: any previous presentation effects, such as line-art color that is not of didactic value; background color or shading effects and 3-dimensional views where 2-d can convey results with equal effectiveness.

  • All text included in figure labels must be of a sufficient size to be legible should the figure be resized during typesetting.

  • Do not include the figure title or figure identification number within the figure itself. This does not reproduce effectively and typically does not fit journal style.

  • Please save your figure files at the highest resolution possible. Please also supply figure art in original file formats whenever possible. Images imbedded in a MS Word document typically do not possess a resolution as high as the original file.

• Have all scientific symbols used in your manuscript transferred successfully to the PDF proof? Please correct this problem before submission.
• All references must be displayed sequentially based upon order of citation. References ordered alphabetically are not acceptable.

Failure to comply with, or perform, these important tasks may delay both peer-review of your manuscript and its eventual publication.