Pharmacology Research & Perspectives
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Pharmacological hypotheses: reviews that are oriented to inform a novel hypothesis
Review articles are often backward looking. On the other hand, novel hypothesis are not normally appropriate for publication, and those that are later shown to be false generally do not make it into the literature in any form. We offer a new opportunity for authors to publish their hypotheses. The paper should take the structure of a grant proposal, with the background material informing the hypothesis, concluding with suggested experimental approaches that might be taken. Indeed, we encourage authors to edit appropriate parts of recently successful grant applications in order to generate a manuscript. The only extra part we would require is a section outlining possible flaws and limitations in the hypothesis (something that may be downplayed in a grant proposal).
Preparation and submission of manuscripts
Standard journal instructions apply with respect to layout, bibliography, ethics acknowledgements etc. Additionally the title should take the form “Pharmacological hypothesis: remainder of title text“. The abstract and the introduction should indicate succinctly but fully the reasoning behind the hypothesis and its context. The discussion is expected to be brief, but it should explain the possible flaws in the hypothesis, and draw attention to any caveats. Please submit the work as a regular article.