Advanced Healthcare Materials
© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Lorna Stimson
Online ISSN: 2192-2659
Associated Title(s): Advanced Electronic Materials, Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Materials, Advanced Materials Interfaces, Advanced Optical Materials, Advanced Science, Biotechnology Journal, ChemMedChem, Macromolecular Bioscience, Particle & Particle Systems Characterization, Small
Materials Science Weekly Newsletter
Recently Published Articles
- Extracellular Matrix-Based Biohybrid Materials for Engineering Compliant, Matrix-Dense Tissues
Laura G. Bracaglia and John P. Fisher
Article first published online: 30 JUL 2015 | DOI: 10.1002/adhm.201500236
Materials made by incorporating polymer components with extracellular matrix (ECM)-derived proteins capitalize on polymer mechanical and degradation properties while still actively guiding tissue remodeling. These characteristics are paramount in engineering a tissue to withstand the force from the environment throughout the remodeling process in skin, vasculature, tendon, and intestinal wall reconstruction.
- Engineering Nanoscale Stem Cell Niche: Direct Stem Cell Behavior at Cell–Matrix Interface
Yan Zhang, Andrew Gordon, Weiyi Qian and Weiqiang Chen
Article first published online: 29 JUL 2015 | DOI: 10.1002/adhm.201500351
Recent exciting advances in nanotechnology and materials science have enabled versatile, robust, and large-scale stem cell engineering in vitro through developments of synthetic nanotopographic surfaces mimicking topological features of stem cell niches. This Progress Report provides a summary of recent progress on emerging methods for generating nanotopographic surfaces and their applications in stem cell research.
- Bioinspired Nanoparticulate Medical Glues for Minimally Invasive Tissue Repair
Yuhan Lee, Chenjie Xu, Monisha Sebastin, Albert Lee, Nathan Holwell, Calvin Xu, David Miranda Nieves, Luye Mu, Robert S. Langer, Charles Lin and Jeffrey M. Karp
Article first published online: 27 JUL 2015 | DOI: 10.1002/adhm.201500419
Methods to deliver viscous medical glues to tissues through small incisions or with small channels are critical for minimally invasive surgeries. Inspired by the granule-packaged glue delivery system of sandcastle worms, nanoparticulate formulation of viscous hydrophobic light-activated adhesive based on poly(glycerol sebacate)-acrylate is shown here.
- Nanomechanics of Cells and Biomaterials Studied by Atomic Force Microscopy
Jason I. Kilpatrick, Irène Revenko and Brian J. Rodriguez
Article first published online: 22 JUL 2015 | DOI: 10.1002/adhm.201500229
Atomic force microscopy is an indispensable tool for nanomechanical measurements of cells, cell microenvironments, and biomaterials. The mechanical properties of cells and their function are influenced by the elasticity of the extracellular matrix. Thus, understanding the nanomechanical properties is key for tissue engineering applications.
- Bright Lu2O3:Eu Thin-Film Scintillators for High-Resolution Radioluminescence Microscopy
Debanti Sengupta, Stuart Miller, Zsolt Marton, Frederick Chin, Vivek Nagarkar and Guillem Pratx
Article first published online: 16 JUL 2015 | DOI: 10.1002/adhm.201500372
Thin-film Lu2O3:Eu scintillators are used to successfully produce high-resolution images of glucose uptake in human cancer cells. The sensitivity of this novel material is quantified and shown to be a fourfold improvement over previously used thicker CdWO4-based scintillators. This work has key implications for high-resolution and real-time imaging of cell metabolism using radiotracers.