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Recently Published Articles

  1. Cell Interactions with Vascular Regenerative MAA-Based Materials in the Context of Wound Healing

    Alexandra Lisovsky, Michael Dean Chamberlain, Laura Anne Wells and Michael Vivian Sefton

    Article first published online: 22 MAY 2015 | DOI: 10.1002/adhm.201500192

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    This Progress Report focuses on a methacrylic acid-based biomaterial, which is a vascular regenerative material that enhances vascularization and diabetic healing without the use of cells or growth factors. The current knowledge of the molecular mechanisms of this biomaterial are reviewed since this may facilitate the development of other therapeutic biomaterials for diverse applications.

  2. M13 Bacteriophage and Adeno-Associated Virus Hybrid for Novel Tissue Engineering Material with Gene Delivery Functions

    So Young Yoo, Hyo-Eon Jin, Dong Shin Choi, Masae Kobayashi, Yohan Farouz, Sky Wang and Seung-Wuk Lee

    Article first published online: 22 MAY 2015 | DOI: 10.1002/adhm.201500179

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    A novel hybrid phage carrying genes from prokaryotic M13 phage and eukaryotic adeno-associated viruses can be used as a tissue engineering material with gene delivery functions. The filamentous shape of the resulting hybrid phage easily forms nanofibrous matrices, which can support cellular growth in tissue culture conditions and deliver the target programmed gene information into the target cells.

  3. Thermally Switched Release from a Nanogel-in-Microfiber Device

    Long Li, Guang Yang, Guangliang Zhou, Yi Wang, Xiaotong Zheng and Shaobing Zhou

    Article first published online: 21 MAY 2015 | DOI: 10.1002/adhm.201500267

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    A nanogel-in-microfiber device, whose release can be switched on and off in response to a temperature change, is successfully developed. The release behaviors are realized through the deswelling and swelling of the nanogels in shell layer of fiber by alternatively elevating and lowering the environmental temperature.

  4. Polyethylene Glycol Coatings on Plastic Substrates for Chemically Defined Stem Cell Culture

    Samantha K. Schmitt, Angela W. Xie, Raha M. Ghassemi, David J. Trebatoski, William L. Murphy and Padma Gopalan

    Article first published online: 20 MAY 2015 | DOI: 10.1002/adhm.201500191

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    A thermally crosslinkable polymer coating, which is compatible with plastic substrates, provides a chemically defined substrate for human stem cell culture. The coating is applied to large areas using low concentrations of Arg–Gly–Asp peptides. Chemically defined passage is demonstrated, as is the ability to tailor the peptide stability through either thioester or amide peptide–polymer bonds.

  5. Cephalopod-Inspired Miniaturized Suction Cups for Smart Medical Skin

    Moon Kee Choi, Ok Kyu Park, Changsoon Choi, Shutao Qiao, Roozbeh Ghaffari, Jaemin Kim, Dong Jun Lee, Myungbin Kim, Wonji Hyun, Seok Joo Kim, Hye Jin Hwang, Seung-Hae Kwon, Taeghwan Hyeon, Nanshu Lu and Dae-Hyeong Kim

    Article first published online: 20 MAY 2015 | DOI: 10.1002/adhm.201500285

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    Biomimetic miniaturized suction cups (mSCs) are designed for the patient friendly, dry adhesives of smart medical skin. Both strong van der Waals force and induced negative pressure by the ultrasoft mSCs facilitate tight skin coupling without discomfort or irritations, improve sensitivities of the embedded stretchable electronics for continuous vital sign monitoring, and enable multiple drug reloading without loss of the adhesion.