Advanced Healthcare Materials

Cover image for Vol. 7 Issue 5

Editor-in-Chief: Lorna Stimson; Deputy Editors: Uta Goebel, Emily Hu

Online ISSN: 2192-2659

Associated Title(s): Advanced Biosystems, Advanced Functional Materials, Advanced Materials, Advanced Materials Technologies, Advanced Science, Biotechnology Journal, Macromolecular Bioscience, Small

Recently Published Issues

See all

Advanced Science Newsletter

Sign up for updates on the latest research!

Recently Published Articles

  1. Toward Immunocompetent 3D Skin Models

    Aleta Pupovac, Berna Senturk, Chiara Griffoni, Katharina Maniura-Weber, Markus Rottmar and Sally L. McArthur

    Version of Record online: 15 MAR 2018 | DOI: 10.1002/adhm.201701405

    Thumbnail image of graphical abstract

    3D human skin models provide a platform for toxicity testing, biomaterials evaluation, and investigation of fundamental biological processes. The wide range of technological and fundamental challenges that need to be addressed to successfully generate immunocompetent skin models is explored and the steps currently being made globally by researchers to achieve this are discussed.

  2. Current Concepts in Meniscus Tissue Engineering and Repair

    Bahar Bilgen, Chathuraka T. Jayasuriya and Brett D. Owens

    Version of Record online: 15 MAR 2018 | DOI: 10.1002/adhm.201701407

    Thumbnail image of graphical abstract

    The meniscus is the most commonly injured structure in the human knee. In this progress report, the current clinical treatments and the state-of-the-art research in cellular therapies, biomaterials, and cell-based tissue engineering strategies for the repair and replacement of meniscus are reviewed, and the current challenges are identified.

  3. Nanofibered Gelatin-Based Nonwoven Elasticity Promotes Epithelial Histogenesis

    Nicole Jedrusik, Christoph Meyen, Günter Finkenzeller, G. Björn Stark, Stephan Meskath, Simon Daniel Schulz, Thorsten Steinberg, Philipp Eberwein, Sandra Strassburg and Pascal Tomakidi

    Version of Record online: 12 MAR 2018 | DOI: 10.1002/adhm.201700895

    Thumbnail image of graphical abstract

    Biomechanical properties influence cell and tissue behavior and consequently biomaterial success in the context of tissue regeneration. Modulus of elasticity of 3.2 kPa of in situ crosslinked gelatin nonwoven mats supports epithelial tissue formation, regarding stratification and differentiation, with no need of in vivo mesenchymal cell counterparts. This novel finding supports the efficient design of biomaterials for adjusted tissue engineering.

  4. NanoTRAIL-Oncology: A Strategic Approach in Cancer Research and Therapy

    Yesi Shi, Xin Pang, Junqing Wang and Gang Liu

    Version of Record online: 12 MAR 2018 | DOI: 10.1002/adhm.201800053

    Thumbnail image of graphical abstract

    Amounts of nanoparticles (e.g., liposomes, polymers, and other functional particles) have been widely investigated to enhance TRAIL antitumor efficacy. Nanoparticle-based TRAIL (NanoTRAIL) has shown a great promise in cancer therapy due to its potential functions, such as enhanced permeability and retention effect, sustained release, active targeting, and synergistic effect combined with chemotherapeutics. The TRAIL-based therapeutic strategies to overcome TRAIL resistance by utilizing nanoformulation and bioengineering are also introduced in this review.

  5. Carbon-Dot-Decorated TiO2 Nanotubes toward Photodynamic Therapy Based on Water-Splitting Mechanism

    Dan Yang, Guixin Yang, Qianqian Sun, Shili Gai, Fei He, Yunlu Dai, Chongna Zhong and Piaoping Yang

    Version of Record online: 12 MAR 2018 | DOI: 10.1002/adhm.201800042

    Thumbnail image of graphical abstract

    A proposed anticancer formulation (carbon nanodots (CDots)/TiO2 nanotubes (NTs)) that is composed of TiO2 NTs and CDots is fabricated. The fabricated CDots/TiO2 NTs show excellent photodynamic therapeutic performances in vitro and in vivo assays based on water splitting. It presents intensive light absorption response and narrows the band gap compared with anatase TiO2.