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Recently Published Articles

  1. Biomaterial-Stabilized Soft Tissue Healing for Healing of Critical-Sized Bone Defects: the Masquelet Technique

    Magdalena Tarchala, Edward J. Harvey and Jake Barralet

    Article first published online: 8 FEB 2016 | DOI: 10.1002/adhm.201500793

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    The Masquelet technique is a two-step surgical procedure used to treat critical-sized bone defects. Although clinically effective, the physiology of healing is not well understood and much has yet to be elucidated and optimized. Multiple modifiable factors have been identified and implemented. This review looks at the factors crucial to the success of the Masquelet technique and how we can further optimize them in clinical practice.

  2. In Vivo Host Response and Degradation of Copolymer Scaffolds Functionalized with Nanodiamonds and Bone Morphogenetic Protein 2

    Salwa Suliman, Yang Sun, Torbjorn O. Pedersen, Ying Xue, Joachim Nickel, Thilo Waag, Anna Finne-Wistrand, Doris Steinmüller-Nethl, Anke Krueger, Daniela E. Costea and Kamal Mustafa

    Article first published online: 8 FEB 2016 | DOI: 10.1002/adhm.201500723

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    Functionalizing poly[(l-lactide)-co-(ε-caprolactone)] scaffolds with nanodiamonds and physisorbed BMP-2 accelerates their degradation and promotes osteogenicity while reducing in vivo foreign-body reactions ectopically in Balb/c mice. Nondegradable nanodiamonds are left in the site of implantation after the scaffold degrades with no adverse effects. This new modality of delivering BMP-2 attenuates inflammatory response while lowering the dose promoting its clinical applications.

  3. You have free access to this content
    Masthead: (Adv. Healthcare Mater. 3/2016)

    Article first published online: 4 FEB 2016 | DOI: 10.1002/adhm.201670014

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    Ultrathin Injectable Sensors: Ultrathin Injectable Sensors of Temperature, Thermal Conductivity, and Heat Capacity for Cardiac Ablation Monitoring (Adv. Healthcare Mater. 3/2016) (page 394)

    Ahyeon Koh, Sarah R. Gutbrod, Jason D. Meyers, Chaofeng Lu, Richard Chad Webb, Gunchul Shin, Yuhang Li, Seung-Kyun Kang, Yonggang Huang, Igor R. Efimov and John A. Rogers

    Article first published online: 4 FEB 2016 | DOI: 10.1002/adhm.201670015

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    On page 373, I. R. Efimov, J. A. Rogers, and co-workers report classes of ultrathin injectable sensors for spatiotemporal determination of temperature, thermal conductivity, and heat capacity of biological tissues. These flexible devices provide unique capabilities in monitoring of depth-dependent changes in the properties of myocardial tissue that result from cardiac ablation therapy. The materials and mechanical designs provide minimally invasive, biocompatible operation.

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    Contents: (Adv. Healthcare Mater. 3/2016) (pages 301–304)

    Article first published online: 4 FEB 2016 | DOI: 10.1002/adhm.201670012