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Recently Published Articles

  1. Nanomaterials for Engineering Stem Cell Responses

    Punyavee Kerativitayanan, James K. Carrow and Akhilesh K. Gaharwar

    Article first published online: 26 MAY 2015 | DOI: 10.1002/adhm.201500272

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    Advanced multifunctional nanomaterials interact with stem cell in a synergistic manner and play key roles in controlling cellular fate, which underline therapeutic success. This Review focuses on recent developments in stem cell-nanomaterial interactions, with specific emphasis on their application in regenerative medicine. Enhanced understanding of nanomaterial-stem cell interactions will facilitate improved biomaterials design for a range of biomedical and biotechnological applications.

  2. A Near Infrared Light Triggered Hydrogenated Black TiO2 for Cancer Photothermal Therapy

    Wenzhi Ren, Yong Yan, Leyong Zeng, Zhenzhi Shi, An Gong, Peter Schaaf, Dong Wang, Jinshun Zhao, Baobo Zou, Hongsheng Yu, Ge Chen, Eric Michael Bratsolias Brown and Aiguo Wu

    Article first published online: 26 MAY 2015 | DOI: 10.1002/adhm.201500273

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    In this study, hydrogenated black TiO2 (H-TiO2) nanoparticles with strong near infrared absorption are coated by polyethylene glycol (PEG) to form H-TiO2-PEG nanoparticles, and then are explored as a novel cancer therapy agent. The findings herein demonstrate that near infrared-triggered H-TiO2-PEG nanoparticles exhibit low toxicity, high efficiency for cancer therapy, and are promising for further biomedical applications.

  3. Cell Interactions with Vascular Regenerative MAA-Based Materials in the Context of Wound Healing

    Alexandra Lisovsky, Michael Dean Chamberlain, Laura Anne Wells and Michael Vivian Sefton

    Article first published online: 22 MAY 2015 | DOI: 10.1002/adhm.201500192

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    This Progress Report focuses on a methacrylic acid-based biomaterial, which is a vascular regenerative material that enhances vascularization and diabetic healing without the use of cells or growth factors. The current knowledge of the molecular mechanisms of this biomaterial are reviewed since this may facilitate the development of other therapeutic biomaterials for diverse applications.

  4. M13 Bacteriophage and Adeno-Associated Virus Hybrid for Novel Tissue Engineering Material with Gene Delivery Functions

    So Young Yoo, Hyo-Eon Jin, Dong Shin Choi, Masae Kobayashi, Yohan Farouz, Sky Wang and Seung-Wuk Lee

    Article first published online: 22 MAY 2015 | DOI: 10.1002/adhm.201500179

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    A novel hybrid phage carrying genes from prokaryotic M13 phage and eukaryotic adeno-associated viruses can be used as a tissue engineering material with gene delivery functions. The filamentous shape of the resulting hybrid phage easily forms nanofibrous matrices, which can support cellular growth in tissue culture conditions and deliver the target programmed gene information into the target cells.

  5. Thermally Switched Release from a Nanogel-in-Microfiber Device

    Long Li, Guang Yang, Guangliang Zhou, Yi Wang, Xiaotong Zheng and Shaobing Zhou

    Article first published online: 21 MAY 2015 | DOI: 10.1002/adhm.201500267

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    A nanogel-in-microfiber device, whose release can be switched on and off in response to a temperature change, is successfully developed. The release behaviors are realized through the deswelling and swelling of the nanogels in shell layer of fiber by alternatively elevating and lowering the environmental temperature.