Advanced Healthcare Materials
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Editor-in-Chief: Lorna Stimson
Online ISSN: 2192-2659
Associated Title(s): Advanced Energy Materials, Advanced Engineering Materials, Advanced Functional Materials, Advanced Materials, Advanced Materials Interfaces, Advanced Optical Materials, Biotechnology Journal, ChemMedChem, Macromolecular Bioscience, Particle & Particle Systems Characterization, Small
Materials Science Weekly Newsletter
Recently Published Articles
- Inhibition of Angiogenesis by Antioxidant Micelles
Masaki Moriyama, Stéphanie Metzger, André J. van der Vlies, Hiroshi Uyama, Martin Ehrbar and Urara Hasegawa
Article first published online: 11 SEP 2014 | DOI: 10.1002/adhm.201400249
Antioxidant micelles having catechol moieties in the core efficiently inhibit angiogenesis by scavenging reactive oxygen species as shown in the human umbilical vein endothelial cells (HUVECs) tube formation and ex ovo chicken chorioallantoic membrane (CAM) assay. These micelles may be useful in anti-angiogenic therapy to treat various diseases such as cancer.
- Elongation of Fibers from Highly Viscous Dextran Solutions Enables Fabrication of Rapidly Dissolving Drug Carrying Fabrics
John P. Frampton, David Lai, Maxwell Lounds, Kyeongwoon Chung, Jinsang Kim, John F. Mansfield and Shuichi Takayama
Article first published online: 10 SEP 2014 | DOI: 10.1002/adhm.201400287
A new method for creating fabrics composed entirely of dextran shows promise for use as a topical drug delivery system for antibiotics and hemostatic agents. This method uses the cohesive and adhesive forces of a highly viscous dextran solution to elongate fibers of approximately 10 μm in diameter between two substrates.
- You have free access to this contentStem Cells: Reconstituting Vascular Microenvironment of Neural Stem Cell Niche in Three-Dimensional Extracellular Matrix (Adv. Healthcare Mater. 9/2014) (page 1349)
Yoojin Shin, Kisuk Yang, Sewoon Han, Hyun-Ji Park, Yun Seok Heo, Seung-Woo Cho and Seok Chung
Article first published online: 8 SEP 2014 | DOI: 10.1002/adhm.201470043
On page 1457 S.-W. Cho, S. Chung, and co-workers show that neural stem cell (NSC)-vascular niche consisting of a brain vasculature and 3D extracellular matrix (ECM) is reconstituted in a microfluidic system. The in vivo-like microenvironment reconstituted in this system allows NSCs to adopt physiologically relevant phenotypes through the combined effects of 3D ECM and vasculature.
- Biomimetic Materials: Peptide-Directed Spatial Organization of Biomolecules in Dynamic Gradient Scaffolds (Adv. Healthcare Mater. 9/2014) (page 1350)
Lesley W. Chow, Astrid Armgarth, Jean-Philippe St-Pierre, Sergio Bertazzo, Cristina Gentilini, Claudia Aurisicchio, Seth D. McCullen, Joseph A. M. Steele and Molly M. Stevens
Article first published online: 8 SEP 2014 | DOI: 10.1002/adhm.201470044
Peptide-polymer conjugates that specifically and dynamically bind glycosaminoglycans are used to functionalize the surface of biodegradable electrospun fiber scaffolds. The versatile platform presented by L. W. Chow, M. M. Stevens, and colleagues on page 1381 can be used to recreate gradients of ECM-like biomolecule organization within scaffolds to achieve more functional and clinically relevant tissue-engineered constructs.