Ultrabright Lanthanide Nanoparticles
Joan Goetz, Dr. Aline Nonat, Abdoulaye Diallo, Mohamadou Sy, Ildan Sera, Alexandre Lecointre, Dr. Christophe Lefevre, Chi Fai Chan, Prof. Ka-Leung Wong and Dr. Loïc J. Charbonnière
Article first published online: 16 FEB 2016 | DOI: 10.1002/cplu.201600007
Put your coat on: Eleven ligands were tested for surface photosensitization of Tb-doped LaF3 nanoparticles. Isolation, purification and characterization of the surface-coated nanoparticles led to extremely bright scaffolds (brightness >106 m−1 cm−1) that are stable in the presence of large excesses of competing anions. The nanoparticles were shown by luminescence microscopy to internalize into HeLa cells and localize to the lysosomes.