ChemPlusChem

Cover image for Vol. 79 Issue 12

Editor: Neville Compton, Deputy Editor: Marisa Spiniello

Impact Factor: 3.242

ISI Journal Citation Reports © Ranking: 2013: 38/148 (Chemistry Multidisciplinary)

Online ISSN: 2192-6506

Associated Title(s): Angewandte Chemie International Edition, Chemistry - A European Journal

Notice to Authors

General Information

About the Journal

ChemPlusChem—A Genuinely Multidisciplinary Journal Centering on Chemistry is a peer-reviewed scientific journal tailored to multidisciplinary chemistry researchers from across the world. Fully comprehensive in its scope, ChemPlusChem publishes original papers describing new results that cover at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem).

ChemPlusChem is co-owned by a group of European chemical societies (ChemPubSoc Europe); they are: the chemical societies of Austria (GÖCh), Belgium (SRC and KVCV), the Czech Republic (ČSCH), France (SFC), Germany (GDCh), Greece (AGS), Hungary (MKE), Italy (SCI), the Netherlands (KNCV), Poland (PTCh), Portugal (SPQ), Spain (RSEQ), and Sweden (SCS) as well as supported by the chemical societies of Slovakia (SCS) and Switzerland (SCG), and is published by Wiley-VCH. ChemPlusChem is a member of the growing family of ChemPubSoc Europe journals that include Chemistry—A European Journal, European Journal of Inorganic Chemistry, European Journal of Organic Chemistry, ChemBioChem, ChemCatChem, ChemElectroChem, ChemMedChem, ChemPhysChem, ChemSusChem, and ChemistryOpen. The Journal is fully electronic and available online. ChemPlusChem publishes 12 online issues per year and succeeds the Collection of Czechoslovak Chemical Communications, which ceased publication at the end of 2011.

ChemPlusChem publishes an attractive mix of Full Papers, Communications, Reviews, and Minireviews. Except for original research papers (Communications and Full Papers) all other article types are generally invited. Unsolicited manuscripts are welcome as long as they fit the scope of the journal. It would, however, be helpful if the Editor is informed of the topic and outline of a proposed Review or Minireview prior to submission.

Color is free to all authors to enhance the readability of their results.

Editorial Policies

ChemPlusChem does not publish manuscripts that have already appeared in print or electronically. The author must inform the Editor of manuscripts submitted, soon to be submitted, or in press at other journals that have a bearing on the manuscript being submitted to ChemPlusChem. If the manuscript is, in fact, a revised/extended version of a manuscript previously rejected by ChemPlusChem, the author must inform the editor about the previous submission in the cover letter and explain in detail the essential changes that have been made. The Ethical Guidelines for Publication in Journals and Reviews issued by the European Association of Chemical and Molecular Sciences are followed and applied by the Editors of ChemPlusChem. Japanese and Chinese translations of Wiley-Blackwell′s Publication Ethics: Best Practice Guidelines on Publication Ethics: A Publisher′s Perspective are available on the Wiley–Blackwell author services homepage and also through the ChemPlusChem homepage (www.chempluschem.org).

In particular, authors should reveal all sources of funding for the work presented in the manuscript and should declare any conflicts of interest. Authors should declare any conflict of interest in their cover letter to the editor, for example support of the research by companies who stand to profit from publication of the results. In cases of suspected plagiarism, submitted manuscripts will be checked with relevant software. Honorary authorship is forbidden, i.e., all co-authors of a manuscript must have contributed significantly to the work being described and/or to the writing of research proposals or the manuscript. In cases of more than three authors, the contribution of each author should be explained in the cover letter. Every author must be informed about the submission and must have agreed to it.

Authors submitting a manuscript to ChemPlusChem for the first time are asked to characterize their main research interests with a maximum of five keywords from the Keyword List for Authors and Reviewers (see our Keyword List guidelines for details).

All manuscripts that are suitable for consideration will be peer reviewed and, if accepted for publication, edited with a view to clarity, brevity, and consistency. The conditions for publication are available on the journal′s homepage. Authors are welcome to suggest reviewers.

If a manuscript was previously submitted to Angewandte Chemie, Chemistry–A European Journal, European Journal of Organic Chemistry, European Journal of Inorganic Chemistry, ChemCatChem or any other of ChemPlusChem′s sister journals, then please state the manuscript number of the previous submission in the cover letter. This will help the peer-review process.

Manuscript Submission

Contributions should be in English and we request that you submit your manuscript by using our online submission system, Editorial Manager, accessible either through our homepage (www.chempluschem.org) via the "Submit an Article" link or directly via www.editorialmanager.com/cplu. For the initial submission of a manuscript, please prepare a single file (allowed formats: Word, RTF, Postscript, PDF) containing all Schemes, Figures, Tables, etc. These elements should be integrated into the text (i.e., inserted where first mentioned), to facilitate evaluation by the Editor and Reviewers. Supporting Information, crystallographic CIF files, and any other additional materials should also be provided during the submission process. A cover letter should be included, and we ask that it include a short text justifying why your article should appear in ChemPlusChem.

When you have all your files ready for submission, go to www.editorialmanager.com/cplu and login as an "Author". Click on "Submit a Manuscript" and follow the step-by-step instructions. Please note that you will be required to view the generated PDF and confirm that it is suitable before the submission process can be completed.

If, for any reason, you are unable to use our online submission site, then you can also send the manuscript to us as a single PDF file along with any Supporting Information and the cover letter via email to chempluschem@wiley-vch.de; please do not forget to provide a signed copy of the Copyright Transfer Agreement (available as a PDF file from www.chempluschem.org).

Please note, however, that online submission is preferred, as this will considerably speed up the manuscript-handling process.

If authors are mandated or want to make their publications freely available from the moment they are published (open access), ChemPlusChem offers such a service. In the OnlineOpen section on our homepage you can find all of the information about this subject. ChemPlusChem also complies with the request or mandate from research funding agencies, for example, the US National Institutes of Health (NIH), to make manuscripts freely available online in the unedited and not proof-read form after acceptance.

In general, we recommend that authors link to their ChemPlusChem publication on their homepage through the "Digital Object Identifier" (DOI). It is only in this way that the Crossref function and full-text downloads can be correctly tallied.

Types of Contribution

1. Reviews

Reviews deal with topics of current interest to the general chemistry readership of ChemPlusChem. Rather than an assemblage of detailed information with a complete literature survey, a critically selected treatment of the material is desired. Unsolved problems and possible developments should also be discussed.

Reviews should be divided into (numbered) sections. Cross-references in the text refer to these section numbers. The review starts with a Lead-in (1000 characters excl. spaces). This text should not be a mere summary, but rather should—together with a frontispiece picture—arouse the readers′ interest. The Introduction should introduce the nonspecialist to the subject as clearly as possible. A Review should conclude with a Summary and Outlook section, in which the achievements and new challenges for the subject are presented succinctly. In addition, a biographical sketch (up to 500 characters excl. spaces) and a portrait-quality color photograph of each author, as well as a graphical suggestion for a full-page picture (Frontispiece; 18 cm wide×19.5 cm high) to face the first page of the review article, should be submitted. The publication of a color frontispiece is free of charge.

A Review should consist of a maximum of approximately 65000 characters (excl. spaces) of main text, footnotes, literature citations, tables, and legends.

Three weeks are allowed for the revision of a Review. If more time is needed the Editor should be informed.

2. Minireviews

A Minireview introduces the reader to a particular area of an author′s research through a concise overview of a selected topic. Minireviews offer the flexibility to treat topics at a time, and in a suitable manner, when a Review would still be premature or inappropriate. The content should balance scope with depth, and references to important works from others that are significant to the topic, should be included.

It should still have an Abstract (1000 characters excl. spaces) that should similarly arouse the readers′ interest. In addition, a biographical sketch (up to 500 characters excl. spaces) and a portrait-quality color photograph of the corresponding author as well as a graphical suggestion for a full-page picture (Frontispiece; 18 cm wide×19.5 cm high) to face the first page of the Minireview article, should be submitted. The publication of a color frontispiece is free of charge.

A Minireview should consist of a maximum of approximately 25000 characters (excl. spaces) of main text, footnotes, literature citations, tables, and legends.

Three weeks are allowed for the revision of a Minireview. If more time is needed the Editor should be informed.

3. Communications and Full Papers

Communications and Full Papers present multidisciplinary results of experimental and/or theoretical studies of general interest or great importance to the development of a specific area of research. A short text justifying why the manuscript should appear in ChemPlusChem should be included in the cover letter provided upon submission. The quality of original research contributions is usually assessed by two or more independent reviewers. Reviewers have the responsibility to return the manuscript without review to the editor if there is a conflict of interest. Specifically, Referees should not review manuscripts authored or co-authored by a person with whom the referee has a close personal or professional relationship, if this relationship could be reasonably thought to bias the review. Detailed information that could be of importance to the reviewers, but that is unlikely to be of interest to the reader can be submitted as an enclosure or clearly marked as Supporting Information. Only articles that have already been published in a scientific journal should be cited. The citation should be fair and informative but not excessive. Copies of cited publications not yet available publicly should be submitted along with the manuscript. Unpublished results and lectures should only be cited in exceptional circumstances.

Inclusive of all references, footnotes, and tables, a Communication should be no longer than approximately 15000 characters. Communications require an Abstract, which should be concise (1000 characters excl. spaces) and not too technical, and should stand alone. Chemical formulae, figures, and schemes may also be added. Longer Communications will be accepted only if their quality warrants special consideration, and a written justification of their length is provided. Communications should not be divided into sections. However, experimental details can be succinctly summarized separately under the heading Experimental Section. Please note, only pertinent experimental information should be included in this section, and any additional experimental data should be detailed in the Supporting Information. Click here for details about Experimental Section requirements. The main text of a Communication should start by giving an introduction to enable readers unfamiliar with the subject to become acquainted with the importance of the results presented. In the final paragraph the results should be summarized succinctly, and one sentence should be devoted to their significance and, if appropriate, to remaining challenges.

Two weeks are allowed for the revision of a Communication. If more time is needed the Editor should be informed.

Full Papers, which generally contain an Experimental Section (see our detailed Experimental Section requirements), have no length restrictions. However, the Editorial Office requests that space be used thoughtfully and economically. ChemPlusChem will not publish Full Papers that consist mainly of results reported in previous Communications with an added experimental section. Full Papers contain an Abstract, which should be concise (1000 characters excl. spaces) and not too technical, and an Introduction including relevant references. The presentation of Results and Discussion may be combined or kept separate. These sections may be further divided by subheadings. The main text of a Full Paper should close with a Conclusion section, summarizing the key findings and future directions.

Three weeks are allowed for the revision of a Full Paper. If more time is needed the Editor should be informed.

4. Correspondence

Critical comments on publications in ChemPlusChem are welcome if they contribute to scientific discussion. The author of the publication to which the Correspondence pertains will have the opportunity to reply. This reply will be sent to the author of the Correspondence. Authors interested in preparing such a contribution should contact the Editor to discuss this further (chempluschem@wiley-vch.de).

5. Corrigenda

Post-publication Corrections Errors recognized only after an article has been published can be corrected. How the correction is carried out depends on the severity of the error. Minor typographical errors and misspellings are left alone as long as reader comprehension of the content remains unaltered. Minor scientifically incorrect or incomplete information in EarlyView articles can be corrected for the article´s eventual publication in an issue, and in these cases, a short text is added toward the end of the paper alerting readers that minor changes have been made since the initial online publication.

Significant scientific errors noted either after a manuscript´s publication in EarlyView or in an issue, should be corrected in a Corrigendum. Corrigenda are published directly after the Table of Contents in the next available issue of the journal and should be kept as short as possible. Authors should first contact the editorial office before they submit the Corrigendum. We request that authors submit the Corrigendum electronically like any other article through Editorial Manager, and that they cite the publication to be corrected along with its digital object identifier (DOI).

Titles and Abstracts

To ensure discoverability of an article when published, authors should take care when drafting their Abstract and deciding on the wording of their Title.

The title should be as succinct as possible and without a reference. Words such as ′new′, ′novel′, ′first′, ′de novo′, and ′unprecedented′ in the title should be avoided. The title should be restricted to no more than 180 characters and be as informative as possible without being over complicated. Key words and phrases should be used in the title and repeated in the abstract as appropriate.

For Full Papers and Communications, the Abstract should describe the motivation for the work, the methods applied, the key results, and the conclusions drawn. The Abstract for other contribution types should summarize the topic under discussion, the main findings and arguments, and place the article into context. Abstracts for Full Papers, Communications, Reviews and Minireviews should be approximately 1000 characters (excl. spaces) in length. In all cases, when you write the Abstract, please keep the following aspects in mind:

1) The abstract should awaken the curiosity of as many readers as possible.

2) The abstract should reflect the content of the paper, and the text should contain several keywords to aid finding the paper online.

3) The abstract must stand alone and should contain neither hints to graphical elements or tables in the paper nor to references, etc., as the abstract will be found and read independently. Furthermore, bold-face compound numbers, while permitted, must be defined to allow the reader to mentally visualize the compound structure being discussed.

4) Please restrict the use of abbreviations to a minimum.

Table of Contents Entry

For all types of contribution, a graphical Table of Contents entry is included in both EarlyView and in the final Issue. A short text for the Table of Contents should be included upon submission. This text should be about six lines (approximately 350 characters excl. spaces) in length and formulated to arouse curiosity. Repetition or paraphrasing of the title and presentation of experimental details should be avoided. In addition, a color graphic to accompany the text should also be provided; the use of color in the Table of Contents is free of charge and strongly encouraged. Pictures should be kept small (5 × 5.5 cm) with minimum detail. We advise restricting the use of text in the graphic and avoiding large complicated schemes.

Cover Pictures

Suggestions for the Front and Back cover pictures (180 mm wide×170 mm high) with an explanatory text (Front, ~600 characters; Back, ~350 characters) beginning with "The front/back cover picture shows..." are welcome. The cover pictures are chosen by the Editor shortly before an issue is to be published. As this offer provides the research of the authors with an increased visibility, we do ask for a fee to be paid by the author. Details are provided upon selection of the cover pictures.

Authors whose works appears on the front cover are asked to provide a Cover Profile. This feature is exclusive to the manuscript highlighted by the cover picture and gives authors the opportunity to showcase their group (and collaborators) as well as their research related to the paper. This separate one-page article includes photographs of the authors (or the group) as well as questions related to the research within the paper being highlighted on the cover. Again, details are provided upon selection of the front cover picture.

Page Proofs and Reprints

The author who submitted the article, which should typically be the correspondence (*) author, will receive page proofs as a compressed PDF file and a Word file. Corrections may be included either as comments in the PDF or as tracked changes in the Word document. Corrections should be returned to the Editorial Office within two days. The main correspondence author will also receive a reprint PDF file, restricted to 25 printouts, free of charge upon publication of the article in an issue of the journal. Additional reprints may be purchased, and an order form is provided along with the page proofs.

Queries regarding manuscripts should be sent to chempluschem@wiley-vch.de.

Supporting Information

Authors may provide Supporting Information upon submission; if the manuscript is accepted, will be made available online via Wiley Online Library. In this event, the author should keep a copy to make available to readers who do not have internet access. This material is peer-reviewed and must therefore be included with the original submission. After acceptance, succinct text and the necessary graphics should be submitted as a single separate PDF file along with the final revised version of the manuscript (note: for production purposes, only in the Supporting Information should the graphics be present as imports in the PDF file and not as separate files). Please do NOT include a Title/Authors page, as a cover page will be generated automatically during production. Supporting Information should not include crystallographic or sequence data that are available from the relevant databases (CCDC or FIZ). In addition, the standard text: "Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cplu.2014xxxxx." should be added as a footnote after the addresses. Also, please ensure that all Greek characters are in the ′Symbol′ font. Color and animated multimedia applications are welcome for Supporting Information.

Preparation of Manuscripts

We have detailed guidelines to assist you in preparing your manuscript for submission to ChemPlusChem. We strongly encourage you to adhere closely to these guidelines, as it significantly facilitates the peer-review process. Authors of accepted manuscripts should refer to the specific requirements for the preparation of production materials.

If you use LaTeX, please send standard LaTeX files only and a PDF file of the manuscript; please do not include your own style sheets or macros. Basically, keep your file as simple as possible. It will not be used directly to typeset your manuscript, but will be converted prior to editing and typesetting (latex2rtf). For further details please consult our “Instructions for LaTeX users” available on our homepage in the section "Author Guidelines".

Contact Information

Regular mail: ChemPlusChem, Postfach 101161, 69451 Weinheim, Germany

Courier services: ChemPlusChem, Boschstrasse 12, 69469 Weinheim, Germany

Telephone: (+49)6201-606-305

Fax: (+49)6201-606-331 or -328

E-mail: chempluschem@wiley-vch.de

Homepage: http://www.chempluschem.org

Keyword List Guidelines

A Keyword List has been developed for the readers of Wiley-VCH journals.

To enable this option, the editors of these journals have compiled a common keyword catalogue. This catalogue is subdivided to facilitate the search for keywords but can also be completely searched. Some of the keywords are used in more than one area. As with all such records, a few guidelines facilitate its use, and these are briefly explained below:

1. At least two of the maximum of five keywords assigned to an article must come from this list.

2. Named reactions will be incorporated only in exceptional cases. Generally the reaction type is selected instead. For example, Diels–Alder reactions will be found under "cycloadditions" and Claisen rearrangements under "rearrangements".

3. Heteroanalogues of compounds are mainly classified under the C variants, for example, (hetero)cumulenes, (hetero)dienes. A few aza and phospha derivatives are exceptions.

4. Compounds with inorganic components that are central to the article are listed under the element, for instance, iron complexes under "iron" and, if appropriate, the ligand type. Some group names such as "alkali metals" exist alongside the names of important members of the group, for example, "lithium". In such cases the group name is used for these members only when comparative studies are described. The members that do not appear separately are also categorized under the group name.

5. A keyword in the form "N ligand" is only chosen if a considerable portion of the paper deals with the coordination of any ligand that coordinates through the atom concerned (in the example, nitrogen).

6. Spectroscopic methods are assigned as keywords only if the article is about the method itself or if the spectroscopic technique has made an important contribution to the problem under investigation.

7. "Structure elucidation" is intended only if the crux of the paper is a structural elucidation or if a combination of several spectroscopic techniques were needed for conclusive solution of the structure.

8. An attempt has been made to avoid synonyms and to select more general concepts rather than specialized terms. Thus the term "double-decker complexes" is excluded in favor of "sandwich complexes". See also points 3 and 4 above.

9. Enzymes should be assigned to one of the six main enzyme classes (hydrolases, isomerases, ligases, lyases, oxidoreductases, transferases).

This list is a "living" catalogue, flexible enough to absorb new developments in chemistry. We therefore welcome all suggestions from our readers and authors that might improve its user-friendliness. The current version of the Keyword List can be found online.

Experimental Section

Length

Experimental Sections (applicable to Full Papers and Communications only) should be given in sufficient detail to enable others to repeat your work. In papers containing theoretical work, technical details such as computational methods should likewise be confined to an appropriately named section. Experimental Sections have no length restrictions in Full Papers. However, the Editorial Office requests that space be used thoughtfully and economically. Additional experimental details supplementary to those described in the article should be provided as Supporting Information, which will be made accessible on Wiley Online Library. ChemPlusChem will not publish Full Papers that consist mainly of results reported in previous Communications with an added experimental section.

If a crystal structure analysis is not an essential part of a manuscript, only a footnote is required indicating where the detailed results can be found. This can be a separate publication or a freely accessible database.

Compound Characterization and Purity

For all new compounds reported in the Experimental Section, sufficient characterization data should be provided to unambiguously identify the structure and to allow identification through comparison by others.

In general, we encourage authors to include as much characterization data as possible for all compounds described, including but not limited to any/all of the following: 1H NMR, 13C NMR, IR, UV/Vis, MS and HRMS data, elemental (combustion) analysis, melting point ranges for solids, Rf values with solvent details. Specific rotation ([α]D20) values should be given for all optically active compounds described.

Those compounds used in biological testing, whether synthesized or obtained from other sources (e.g., commercial), should possess a purity of no less than 95%. Purity may be determined by any established method (e.g., HPLC, elemental analysis with accuracy within ±0.4%). The purity should be stated, along with the method used to determine it, in the Experimental Section and if appropriate, evidence can be provided in the Supporting Information.

Equipment and Software

Equipment (including make, model, and manufacturer if uncommon), and details of any software used (including version, release date if applicable, and developer) and conditions used for the measurement of physical data, as well as any organisms, proteins, or nucleic acids used, should be described at the beginning of the Experimental Section. Sources of less-common starting materials must be given, and solvent details should also be described.

Compound names

In so far as is practical, authors should use a systematic name for each title compound in the Experimental Section (as suggested by IUPAC, IUBMB, or Chemical Abstracts) followed by the compound number. Please do not use computer programs to generate elaborate systematic names or use extremely long compound names.

When describing the protocol for the synthesis of a given title compound, the full name followed by the compound number in parentheses should be given in bold. When referring to the compound in the running text of the protocol, parentheses for the compound number should be used only if the name identifies the compound uniquely and unambiguously (for example: "...2-ethyl-4-cyanobenzoate (7) was added to..." or: "...cyanobenzoate 7 was added to..."). For the sake of clarity general descriptors such as compound 1, dendrimer 2, or alcohol 3 should be used in the running text rather than the full systematic name.

General Comments and Format

The Experimental Section should be written in the past tense. Quantities of reactants, solvents, etc. should be included in parentheses rather than in the running text (e.g., "Triphenylstannyl chloride (0.964 g, 2.5 mmol) in toluene (20 mL)..."). Physical data (in SI units whenever possible) should be quoted with decimal points and negative exponents (e.g., 25.8 JK−1mol−1). Products should be described, and yields should be given as both a quantity (mol or g) and in percent (e.g., "...compound 7 as a white powder (34 mg, 89%)...").

In special cases, for example, when the compound is unstable or not available in sufficient quantities for complete analysis, the exact relative molecular mass obtained from a high-resolution mass spectrum and a clean 13C NMR spectrum (as Supporting Information for inspection by the reviewers) should be supplied.

Data in the Experimental Section should be carefully and consistently formatted according to the journal style. Examples: "...gave compound 7 as a white powder (34 mg, 89%): Rf=0.38 (CHCl3/MeOH 9:1); m.p.: 70–71°C; [α]D20=−13.5 (c=0.2 in acetone); 1H NMR (400 MHz, [D8]THF, 25°C, TMS): δ=0.88 (t, J=7.2 Hz, 3H), 1.21–1.61 (m, 7H), 2.13 (s, 3H), 3.28 (dd, J=9.0, 7.6 Hz, 1H), 6.75 (d, J=7.9 Hz, 2H), 7.45 ppm (t, J=7.3 Hz, 2H); 13C NMR (75 MHz, [D6]DMSO, 25°C, TMS): δ=13.9, 21.2, 124.5 (2C), 125.8 (2C) 147.6, 175.0 ppm; IR (KBr): ν˜==3248, 3056, 1790, 1780, 1506, 1493 cm−1; UV/Vis (CH2Cl2): λmax (ε)=320 (5000), 270 nm (12000 mol−1dm3cm−1); fluorescence (CH2Cl2): λex=435.5 nm; λem=659, 726 nm; MS (EI): m/z (%): 494 [M+H]+, 476, 392, 348, 268, 217, 174, 139, 123, 91 (100), 77, 55, 41; HRMS (ESI): m/z calcd for C32H47NO5+Na+: 548.3352 [M+Na+]; found: 548.3331; elemental analysis calcd (%) for C29H35NO4S (493.7): C 70.56, H 7.15, N 2.84, S 6.50; found: C 70.65, H 7.06, N 2.93, S 6.58. Please give data in this order.

Animal and Human Subjects

Manuscripts containing animal experiments must include a statement that permission was obtained from the relevant national or local authorities. The institutional committees that have approved the experiments must be identified and the accreditation number of the laboratory or of the investigator given where applicable. If no such rules or permissions are in place in the country where the experiments were performed, then this must also be clearly stated.

Manuscripts with experiments with human subjects or tissue samples from human subjects must contain a disclaimer in the Experimental Section to state that informed signed consent was obtained from either the patient or from next of kin.

Structure and Sequence Data

Prior to manuscript submission, the author(s) must deposit the following information in the appropriate databases: the data of X-ray structure analyses of inorganic and organic compounds, proteins, or nucleic acids; structure determination of proteins and nucleic acids by NMR spectroscopy (together with a list of NEOs), and sequence determinations of proteins or nucleic acids. The name of the database and the deposition number(s) assigned by this database must be stated in the part of the manuscript where the respective structure or sequence determination(s) is described so that reviewers can retrieve the information electronically. Detailed instructions for data submission can be found on the WWW homepages of the databases listed below.

If a crystal structure analysis is not an essential part of the paper, only a footnote is required indicating where the detailed results can be found. Otherwise, the following data should be given in the manuscript: crystal dimensions, crystal system, space group, unit cell dimensions and volume, ρcalcd, 2θmax, radiation, wavelength, scan mode, temperature of measurement, no. of measured and independent reflections, no. of reflections included in refinement, σ limits, whether and how Lorentzian polarization and absorption corrections were performed (μ, min/max transmission), method of structure solution and program, method of refinement and program, no. of parameters, treatment of H atoms. R, wR, whether refined against |F| or |F2|, residual electron density, and the database in which the detailed results are deposited. An ORTEP-type plot will not be reproduced when it merely serves to confirm the structure of a synthetic intermediate.

Structure Data

Organic and organometallic compounds: Crystallographic data should not be sent as Supporting Information, but should be deposited with the Cambridge Crystallographic Data Centre (CCDC) at http://www.ccdc.cam.ac.uk/services/structure_deposit.

Authors must deposit their data before submitting their manuscripts or update data already available, so that reviewers can retrieve the information directly from the database. Please use the free online Checkcif service provided by the International Union of Crystallography and submit the Checkcif report along with your manuscript. Please ensure that the data deposited with the database are identical to those in the manuscript.

The data will be assigned a registry number, which should be included with the following standard text in the manuscript: "CCDC ... contain(s) the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif."

Inorganic compounds, elements, metals, or minerals: Fachinformationszentrum Karlsruhe (FIZ; http://www.fiz-karlsruhe.de).

You will be given a CSD number, which should be included with the following standard text in the manuscript: "Further details of the crystal structure investigation(s) can be obtained from the Fachinformationszentrum Karlsruhe, 76344 Eggenstein-Leopoldshafen, Germany (fax: (+49)7247-808-666; e-mail: crysdata@fiz-karlsruhe.de, http://www.fiz-karlsruhe.de/request_for_deposited_data.html) on quoting the depository number CSD ..."

Proteins and nucleic acids: Protein Data Bank (http://www.rcsb.org/pdb).

NMR spectroscopy data: BioMagResBank (http://www.bmrb.wisc.edu).

Sequence Data

Nucleic acids: GenBank (WWW: http://www.ncbi.nlm.nih.gov/) or EMBL Nucleotide Sequence Database (http://www.ebi.ac.uk/embl/index.html).

Proteins: Protein Information Resource (PIR; http://pir.georgetown.edu/) or SWISS-PROT (http://www.expasy.ch/sprot/sprot-top.html).

Please note that the data in databanks must be released, at the latest, upon publication of your manuscript.

Manuscript Preparation

The following remarks aim to assist you in preparing your manuscript for submission to ChemPlusChem. We strongly encourage you to adhere closely to these guidelines as it facilitates the evaluation of your article by the Editors and Reviewers. Manuscripts that are not suitable for consideration by the reviewers because of poor presentation will be returned to the authors for improvement prior to being sent out for peer evaluation.

Please note, authors of accepted articles looking for guidelines on preparing their production materials should consult the section below entitled "Guidelines for Accepted Manuscripts: Production Material Preparation" for specific requirements in addition to the general comments given below.

General Remarks

Spelling may be either UK or US standard English, but consistency should be maintained within a manuscript. Authors are asked to make their manuscripts suitable for a heterogeneous readership—please use a simple, clear style, and avoid jargon. In some cases, it might be helpful for manuscripts to be checked by a third party, such as Wiley English Language Editing Services, for correct language usage before submission.

Abbreviations and acronyms should be used sparingly and consistently, following the system of abbreviations and symbols recommended by the International Union of Pure and Applied Chemistry (IUPAC) and the International Union of Biochemistry and Molecular Biology (IUBMB). Where they first appear in the text, they should—apart from the most common ones such as NMR, IR, or UV—be defined. You may prefer to explain large numbers of abbreviations and acronyms in a Glossary at the end of the text. Names of organisms should comply with genetic conventions, with genus and species names written in italics and spelled out in full on first appearance. Abbreviations for genes should be written in lower-case letters and italicized, those of the corresponding protein products should start with a capital letter and should not be italicized (e.g., hsp70 and Hsp70, respectively). Enzyme names should be accompanied by the respective Enzyme Commission (EC) numbers.

All other types of contribution should include a short text and color graphic for the Table of Contents. The text should be about six lines (approximately 350 characters excl. spaces) in length and formulated to arouse curiosity. Repetition or paraphrasing of the title and presentation of experimental details should be avoided. The color graphic should be kept small (ideally 5 × 5.5 cm) with minimum detail. We advise restricting the use of text in the graphic and avoiding large complicated schemes. Note, the use of color in the Table of Contents is free of charge and strongly encouraged.

When preparing the manuscript for initial submission and evaluation, we encourage the use of color where necessary to facilitate the scientific understanding and aid in the overall presentation of the manuscript. Color is free to all authors.

A maximum of five keywords should be given. In order to aid online searching, at least two of the keywords should be taken from the Keyword List. Please also see our Keyword List guidelines for details.

Detailed facts of importance to specialist readers can be submitted as Supporting Information and will be made accessible to reviewers and, if accepted, to readers via Wiley Online Library. There is no charge for the use of color in the Supporting Information. Animated multimedia applications, such as movies, and so on are welcome as Supporting Information.

If a crystal structure analysis or sequence determination is not an essential part of a manuscript, only a footnote is required indicating where the detailed results can be found. This can be a separate publication or a freely accessible database. Further, more specific guidelines, are given elsewhere on the requirements for structural data.

If a manuscript is not accepted, all original material is returned to the correspondence author. However, if a manuscript is accepted for publication, graphical material and electronic storage media will only be returned upon request.

Manuscript Organization

Your manuscript can be evaluated more efficiently if it is arranged as described below. Unless stated otherwise, the following instructions apply to all categories of contributions.

Title page (in order): title; authors names with academic titles, alphabetical footnotes ([a],[b],...) referring to addresses, and an asterisk to denote the corresponding author(s); footnotes containing affiliations of all authors including the full postal address, and e-mail address of the corresponding author(s); series title, number, and reference to the previous paper in the series, if applicable; dedication, if applicable.

Keywords: A maximum of five keywords to appear in the printed and online indexes should be given in alphabetical order. At least two keywords should be taken from the Keyword List to aid online searching. As mentioned above, please refer to our Keyword List guidelines for details.

In the text body, compound numbers should be used in ascending order. Compound numbers are always in bold; parentheses for the compound number should be used only if the name identifies the compound uniquely and unambiguously (for example: "...2-ethyl-4-cyanobenzoate (7) was used...", or: "...cyanobenzoate 7 was used..."). Please do not use computer programs to generate elaborate systematic names or use extremely long compound names. For the sake of clarity general descriptors such as compound 1, dendrimer 2, or alcohol 3 are recommended for the body text, reserving longer IUPAC nomenclature for the Experimental Section.

Experimental Section (applicable to Full Papers and Communications only) should be given in sufficient detail to enable others to repeat your work. Please see the Experimental Section guidelines for specific information about formatting and requirements for compound purity and characterization data.

Acknowledgements should include relevant funding agencies.

References: In the text numbers corresponding to the appropriate reference should be typed in square brackets as superscript (e.g., Blobel[3]) and after any punctuation, where applicable. References must be listed in order of their appearance in the text. Please do not format the references section with the Numbering function on your word-processing program. If you use the automatic reference collation system of your word-processing program (Footnotes, EndNote), please convert the references into normal, typed text before submission of the final manuscript, otherwise they may disappear when typeset. Journal titles should be abbreviated according to the Chemical Abstracts Service Source Index (CASSI). Unpublished results and lectures should only be cited for exceptional reasons.

Please follow the examples below. The page range is optional but its presence or absence should be consistent throughout any given manuscript.

Journals: [1] a) B. M. Trost, Chem. Eur. J. 1998, 4, 2405–2412; b) P. Sears, C.-H. Wong, Angew. Chem. Int. Ed. 1999, 38, 2300–2324; Angew. Chem. 1999, 111, 2446–2471.

[2] a) W. D. Wagner, Ann. N.Y. Acad. Sci. 1985, 454, 52–68, and references therein; b) J. C. Wang, Sci. Am. 1982, 247, 94–97.

Books (Without editor): [3] E. Wingender, Gene Regulation in Eukaryotes, VCH, Weinheim, 1993, p. 215.

Books (With editor): [4] T. D. Tullius in Comprehensive Supramolecular Chemistry, Vol. 5 (Eds.: J. L. Atwood, J. E. D. Davies, D. D. MacNicol, F. Vögtle, K. S. Suslick), Pergamon, Oxford, 1996, pp. 317–343.

Miscellaneous: [5] a) C. R. A. Botta (Bayer AG, Berlin, Germany), German Pat. DE-B 2235093, 1973 [Chem. Abstr. 1974, 80, 55356 c]; b) A. Student, PhD thesis, University of Newcastle (UK), 1991; c) "Synthesis in Biochemistry": R. Robinson, J. Chem. Soc. 1936, 1079, f) G. M. Sheldrick, SHELXS-96, Program for the Solution of Crystal Structures, University of Göttingen, Göttingen (Germany), 1996:

Figures, Schemes, Tables and other elements: When preparing your manuscript for evaluation by the Editor and Reviewers, graphical elements should appear, with their legend or footnotes if appropriate, within the main text of the article where first mentioned. Each figure and scheme should have a legend. These should be listed immediately below the graphic, within the main body of the manuscript. Tables must have a brief title and should only be subdivided by three horizontal lines (head rule, neck rule, foot rule). Footnotes in tables are denoted [a], [b], [c], etc. and should contain all additional details. For tables reporting biological data, details of the number of independent experiments, the number of replicates, and errors (SD or SEM) should be given either in the table body or as a general statement in the footnote.

Illustrations (structural formulae, figures, schemes) should, if possible, be designed for reduction to a one-column format (8.5 cm wide). The maximum width is the two-column format (17.5 cm wide). Further guidelines on the graphical representation standards for chemical structure diagrams have been published by IUPAC. To allow the Editor and Reviewers to easily interpret the graphics, care should be taken to ensure all text is legible and all images are clear and of high quality. We recommend: a sans serif font (e.g., Helvetica) for script; size of lettering, 3–3.5 mm; total maximum width, 14 cm (or 28 cm for two-column width). Please use only one size of writing in any one diagram; if two sizes are absolutely necessary, please keep the font sizes to within 2 pt. Please also use only one style of font; the journal style requires a sans serif font (e.g., Helvetica). Writing above the arrow in a scheme may be a little smaller.

Computer-aided image enhancement is often unavoidable. However, such manipulation cannot result in data that are less relevant or unrepresentative being shown and/or genuine and significant signals being lost. A clear relationship must remain between the original data and the electronic images that result from those data. If an image has been electronically modified, the form of the modification must be given in the Figure caption. If computer-aided processing or modification of an image is a fundamental part of the experimental work, then the form that this processing takes must be clearly described in the Experimental Section. A common example of this is the presentation of Western blots; authors should state clearly in the figure legend how a gel was modified, and if appropriate, provide the full gels as Supporting Information for consideration by the Editor and Reviewers.

Please italicize symbols of physical quantities in both graphics and the text, but not their units (e.g., T for temperature, in contrast to T for the unit Tesla; J, but Hz; a, but nm). Stereochemical information (cis, Z, R, etc.), locants (N-methyl, α-amino), and symmetry designations (C2v) should also be italicized. Chemical formulae should be numbered with boldface Arabic numerals (e.g., 1). Labels of axes should be separated from their units by a slash (e.g., T / K). Abbreviations such as Me, Et, nBu, iPr, sBu, tBu, and Ph (not φ) may be used. General substituents should be indicated by R1, R2 (not R2, which means 2R), or R, R′. The spatial arrangement of the substituents should be indicated by hatched lines or a wedge. A minus sign must be as long as the crossbar of a plus sign. Microscopy images (optical, electron, or scanning probe) should always contain a scale bar.

Mathematical formulae should not be incorporated into the text as graphic files. Please type mathematical formulae as normal text in the body of the text as far as is possible.

Guidelines for Accepted Manuscripts: Production Material Preparation

The guidelines below are applicable only to authors of accepted manuscript who are preparing the final revised version. Authors preparing to submit an article to ChemPlusChem as a new submission should consult the section above entitled "Manuscript Preparation".

The final revised version of the manuscript along with the rest of the production materials (graphics, etc.; see below for instructions) should be submitted after the paper has been accepted for publication via our online system using your personal login details or by e-mail. Please note however, that the preferred method of submission of the final versions of manuscript is through your personal homepage.

Please consult the checklist provided as an attachment upon acceptance to ensure that your manuscript complies with the journal requirements. If appropriate, a response letter should be provided along with the production materials outlining the changes made to the manuscript in response to the comments of the reviewers, or if you disagree with their suggestion(s), outlining your arguments against their remarks.

Once the final modifications to the manuscript have been made, to facilitate the typesetting process and preparation of your page proofs, please follow these simple steps:

1. Please remove the text from the submission template and instead present the text as a standard document (single-column, no page header or section breaks). The text should be typed as "continuous text", that is, with carriage returns only at the end of a paragraph, title, heading, and similar features. The text should be provided either as a Word document (.doc) or in rich text format (.rtf).

2. Please remove all graphics from the text; these should be provided as separate files (see below). Our typesetter will insert the graphics where they are mentioned in the text, therefore, please ensure all Figures and Schemes are mentioned in sequence.

3. Tables are edited in the text and therefore should not be sent as graphical elements but rather should be generated in Word and provided at the end of the manuscript text file. The tables should be set up with tabulators, not with the space bar or line breaks.

4. For Tables containing structures, these may be left in the word document for reference but should also be provided as a graphic file. When supplying these structures in the original file format (i.e., ChemDraw or ISISDraw), all structures may be contained within a single file if easier.

5. Each Scheme, Figure, or Formula, as well as the graphic for the Table of Contents, should be provided in their original file format (e.g., PowerPoint, ChemDraw, etc.) or as high-resolution image files (.tiff, .jpeg, etc.). Graphics embedded in word documents are not useable due to the loss of resolution when extracted for the purpose of typesetting. Graphics should be revised to adhere to the journal house style outlined in the Checklist provided upon acceptance. To ensure trouble-free reproduction of the manuscript, please adhere closely to the guidelines given here and in the Checklist.

6. Any Supporting Information should be provided as a separate document in PDF format; Author/Title information for Supporting Information files should not be included, as a cover sheet containing this information is generated automatically during the production process.

7. Preferred word-processing programs are: Microsoft Word for Windows 6.0, 7.0, and updates, WordPerfect, and Macintosh files, preferably stored in Word format. Documents prepared with other word-processing programs should be converted if possible. ChemTex files, for example, cannot be used.

8. Please avoid end-of-line word divisions; if necessary, these are included automatically by our typesetter and can be reviewed prior to publication in the page proofs. Please use only one font type, except for Greek letters, which should be typed in the Symbol font.

9. Formula numbers, and in the reference section, the year of publication (but not headings such as "Table 1" or "Figure 1") should be in boldface or doubly underlined. The symbols for 1 (one) and l ("ell"), 0 (zero) and O ("oh") should be distinct.

10. The manuscript should not be fragmented into separate files. Please save only the graphics and the Supporting Information as separate files.

Structure and Sequence Data

If not already done prior to the original manuscript submission, authors of accepted papers must deposit structural and sequence information in the appropriate databases, as indicated above in the Experimental Section guidelines. Detailed instructions for data submission can be found on the WWW homepages of the databases listed in that section as well.

Please remember that the data in databanks must be released, at the latest, upon publication of your manuscript.

Supporting Information

After manuscript acceptance, succinct text and the necessary graphics should be submitted as a single separate PDF file along with the final revised version of the manuscript. Only in the Supporting Information should the graphics be present as imports in the PDF file and not as separate files. The Supporting Information should be exactly as an Author wishes it to appear to readers; as such, Authors should check the PDF carefully to ensure the graphics are clearly and appropriately presented. Please do NOT include a Title/Authors/Affiliations page, as a cover page for the Supporting Information including these details is generated automatically during production. Supporting Information should not include crystallographic or sequence data that are available from the relevant databases. Also, please ensure that all Greek characters are in the ′Symbol′ font. There is no charge for the use of color in the Supporting Information. Animated multimedia applications, such as movies, and so on are welcome as Supporting Information.

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