Asian Journal of Organic Chemistry
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
The Asian Journal of Organic Chemistry publishes strictly peer-reviewed primary and secondary research in all aspects of organic chemistry. ...
Recently Published Articles
- Scandium(III) Triflate Catalyzed Direct Cyclization of Ketoamides for the Synthesis of 3-Hydroxy-2-Oxindoles
Hong-Li Wang, Ya-Min Li, Gang-Wei Wang, Heng Zhang and Prof. Shang-Dong Yang
Article first published online: 17 MAY 2013 | DOI: 10.1002/ajoc.201300057
Not so scand-alous: We report a scandium(III) triflate catalyzed intramolecular Friedel–Crafts alkylation for the synthesis of 3-hydroxy-2-oxindoles. In comparison with nucleophilic conjugate additions of organometallic or electron-rich reagents to isatins and intramolecular addition of aryl chlorides to ketoamides, this protocol is simple, produces less waste, and omits organometallic reagents and halogenations. Bn=benzyl; DME=1,2-dimethoxyethane.
- Synthesis of Highly Functionalized Aminoindolizines by Titanium(IV) Chloride Mediated Cycloisomerization and Phosphine-Catalyzed Aza-Michael Addition Reactions
De Wang, Yin Wei and Min Shi
Article first published online: 15 MAY 2013 | DOI: 10.1002/ajoc.201300062
TiCl-ing your fancy: A simple and highly efficient synthetic method for the preparation of indolizines from the reaction of 2-enoylpyridines with sulfonamides in the presence of TiCl4 under mild conditions has been developed. A subsequent phosphine-catalyzed aza-Michael reaction of the corresponding indolizines with vinyl ketones and activated allenes was also developed, which affords highly functionalized indolizines in excellent yields under mild conditions.
- Catalyst-free Synthesis of Betti bases in a Mannich-Type Reaction (pages 395–398)
Prof. Mazaahir Kidwai and Ritika Chauhan
Article first published online: 3 MAY 2013 | DOI: 10.1002/ajoc.201300039
Betti you can: An efficient, sustainable, and a catalyst-free procedure for the synthesis of Betti bases by a one-pot, three-component, Mannich-type condensation of secondary amines, aldehydes, and β-naphthol in polyethylene glycol at room temperature has been developed. The products do not require purification by chromatography and the solvent was remarkably recyclable for up to four runs.
- 1,4-Phenylene and 2,5-Thienylene π-Linkers in Charge-Transfer Chromophores (pages 422–431)
Prof. Jiří Kulhánek, Prof. Filip Bureš, Jakub Opršal, Dr. Wojciech Kuznik, Dr. Tomáš Mikysek and Prof. Aleš Růžička
Article first published online: 2 MAY 2013 | DOI: 10.1002/ajoc.201300063
Not such a pushover: The properties of 15 D-π-A chromophores that feature ferrocene donors and NO2 acceptors were investigated by X-ray analysis, electrochemistry, absorption spectroscopy, and DFT calculations. Systematic replacement of 1,4-phenylene with 2,5-thienylene π-linker subunits considerably affects the electronic properties of the push-pull chromophores. Thiophene proved to be a polarizable moiety that allows substantial intramolecular charge transfer.
- Supramolecular Engineering of Perylene Bisimide Assemblies Based on Complementary Multiple Hydrogen Bonding Interactions
Dr. Tomohiro Seki, Dr. Xu Lin and Prof. Dr. Shiki Yagai
Article first published online: 24 APR 2013 | DOI: 10.1002/ajoc.201300025
PBI Friday: Functional perylene bisimide assemblies that are constructed based on complementary multiple hydrogen-bonding interactions are reviewed. Supramolecular engineering of well-defined, hydrogen-bonded oligomers or polymers results in the formation of predictable extended assemblies through π–π stacking interactions. The unique optoelectronic and stimuli-responsive properties as well as the various morphologies of such assemblies are also introduced.