Asian Journal of Organic Chemistry
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Recently Published Issues
January 20, 2014
Subscription Now Available
For the past two years, AsianJOC has brought you excellent research for free. This trial period is now over. Please consider a subscription or recommend the journal to your librarian. AsianJOC is owned by ACES, a consortium of Asian chemical societies. The individual societies will benefit from the revenues and so will the communities they serve.
There will be an updated version of our iPad app in the App Store in a few days. It fully supports subscriptions and will also work on the iPhone.
Recently Published Articles
- Stereoselective NH Insertion-Arylation Reactions of Nitrodiazoesters
Sonia S. So and Prof. Anita E. Mattson
Article first published online: 11 MAR 2014 | DOI: 10.1002/ajoc.201300285
Double the umpolung, double the fun: Chiral phosphoric acid derivatives catalyse NH insertion/arylation reactions of nitrodiazoesters, anilines, and indoles. This process enables access to doubly α-electrophilic esters, that is, two nucleophiles undergo addition to the alpha-carbon atom of an ester. The aryl glycine products are prepared in good yield with modest levels of stereocontrol.
- Copper(I) Iodide Catalyzed Aerobic Oxidative CN and CS bond formations through CH Activation: Synthesis of Functionalized Imidazo[1,2-a]pyridines
Darapaneni Chandra Mohan, Sadu Nageswara Rao, Chitrakar Ravi and Dr. Subbarayappa Adimurthy
Article first published online: 11 MAR 2014 | DOI: 10.1002/ajoc.201402004
Cop that! A general and efficient method for the synthesis of imidazo[1,2-a]pyridines through CH activation with methyl ketones in water catalyzed by copper(I) iodide is described. One-pot, three-component coupling reactions to access sulfenylimidazo[1,2-a]pyridines have also been developed. MCR=multicomponent reaction.
- Phase-Transfer-Catalyzed Asymmetric α-Arylation of α-Amino Acid Derivatives
Dr. Seiji Shirakawa, Kenichiro Yamamoto, Takashi Tokuda and Prof. Dr. Keiji Maruoka
Article first published online: 5 MAR 2014 | DOI: 10.1002/ajoc.201400004
Set phasers to transfer: Highly enantioselective α-arylation of α-amino acid derivatives was achieved under phase-transfer conditions. This reaction demonstrates a valuable method for the catalytic asymmetric synthesis of α,α-disubstituted α-amino acids containing an aromatic substituent. PTC=phase-transfer catalyst; Tf=trifluoromethanesulfonyl.
- Asymmetric Synthesis of Tetrahydroquinolines via Saegusa-type Oxidative Enamine Catalysis/1,5-Hydride Transfer/Cyclization Sequences
Chang Won Suh, Saet Byeol Woo and Prof. Dr. Dae Young Kim
Article first published online: 5 MAR 2014 | DOI: 10.1002/ajoc.201400022
Enamine catalysis you Sae? The organocatalytic Saegusa-type oxidative enamine catalysis/1,5-hydride transfer/ring closure reaction is described. This neutral reaction cascade allows for the efficient formation of ring-fused tetrahydroquinolines in high enantioselectivity. DNBS=2,4-dinitrobenzensulfonic acid; TMS=trimethylsilyl.
- Organocatalytic Enantio- and Diastereoselective Assembly of Thiazolidine Scaffolds by Formal [3+2] Annulation
Hui Qian and Prof. Jianwei Sun
Article first published online: 5 MAR 2014 | DOI: 10.1002/ajoc.201400025
Great balls of thia: An organocatalytic formal [3+2] annulation is described. With readily available achiral starting materials, a range of thiazolidines can be assembled in excellent yield and with moderate to good enantioselectivity and diastereoselectivity.