Biotechnology Progress

Cover image for Vol. 30 Issue 5

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Michael M. Domach

Impact Factor: 1.883

ISI Journal Citation Reports © Ranking: 2013: 40/123 (Food Science & Technology); 90/165 (Biotechnology & Applied Microbiology)

Online ISSN: 1520-6033

Associated Title(s): AIChE Journal, Environmental Progress & Sustainable Energy, Process Safety Progress

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  1. 1 - 55
  1. Cell Culture and Tissue Engineering

    1. You have full text access to this OnlineOpen article
      Uncovering methods for the prevention of protein aggregation and improvement of product quality in a transient expression system

      Bram Estes, Yueh-Rong Hsu, Lei-Ting Tam, Jackie Sheng, Jennitte Stevens and Raj Haldankar

      Article first published online: 25 NOV 2014 | DOI: 10.1002/btpr.2021

  2. Formulation and Engineering of Biomaterials

    1. Proteolytically stabilizing fibronectin without compromising cell and gelatin binding activity

      Chen Zhang, Anand Ramanathan and Nancy Wangechi Karuri

      Article first published online: 24 NOV 2014 | DOI: 10.1002/btpr.2018

  3. Cell Culture and Tissue Engineering

  4. Bioseparations and Downstream Processing

    1. Acetone–butanol–ethanol competitive sorption simulation from single, binary, and ternary systems in a fixed-bed of KA-I resin

      Jinglan Wu, Wei Zhuang, Hanjie Ying, Pengfei Jiao, Renjie Li, Qingshi Wen, Lili Wang, Jingwei Zhou and Pengpeng Yang

      Article first published online: 24 NOV 2014 | DOI: 10.1002/btpr.2019

    2. Reusable nanocopy machine particles for the replication of DNA

      Rıdvan Say, Özlem Biçen Ünlüer, Arzu Ersöz, Cem Öziç and Volkan Kılıç

      Article first published online: 21 NOV 2014 | DOI: 10.1002/btpr.2016

  5. Formulation and Engineering of Biomaterials

    1. A comparative study of monoclonal antibodies. 1. phase behavior and protein–protein interactions

      Rachael A. Lewus, Nicholas E. Levy, Abraham M. Lenhoff and Stanley I. Sandler

      Article first published online: 19 NOV 2014 | DOI: 10.1002/btpr.2011

  6. Cell Culture and Tissue Engineering

  7. Bioseparations and Downstream Processing

  8. Biocatalysts and Bioreactor Design

    1. A two-enzyme immobilization approach using carbon nanotubes/silica as support

      Kun Du, Jian Sun, Xiaoyu Zhou, Wei Feng, Xia Jiang and Peijun Ji

      Article first published online: 15 NOV 2014 | DOI: 10.1002/btpr.2010

  9. Cell Culture and Tissue Engineering

    1. The interplay of cyclic stretch and vascular endothelial growth factor in regulating the initial steps for angiogenesis

      Justin R. Wilkins, Daniel B. Pike, Christopher C. Gibson, Li Li and Yan-Ting Shiu

      Article first published online: 13 NOV 2014 | DOI: 10.1002/btpr.2017

  10. Bioseparations and Downstream Processing

    1. Effects of chemical sanitization using NaOH on the properties of polysulfone and polyethersulfone ultrafiltration membranes

      Achyuta Teella, Andrew L. Zydney, Hongyi Zhou, Cathryn Olsen and Craig Robinson

      Article first published online: 13 NOV 2014 | DOI: 10.1002/btpr.2008

  11. Biocatalysts and Bioreactor Design

  12. Bioseparations and Downstream Processing

    1. Ionic liquid-based aqueous biphasic systems as a versatile tool for the recovery of antioxidant compounds

      João H. Santos, Francisca A. e Silva, Sónia P. M. Ventura, João A. P. Coutinho, Ranyere L. de Souza, Cleide M. F. Soares and Álvaro S. Lima

      Article first published online: 31 OCT 2014 | DOI: 10.1002/btpr.2000

  13. Cell Culture and Tissue Engineering

  14. Applied Cellular Physiology and Metabolic Engineering

    1. Increasing available NADH supply during succinic acid production by Corynebacterium glutamicum

      Zhihui Zhou, Chen Wang, Yali Chen, Kai Zhang, Hongtao Xu, Heng Cai and Zhongjun Chen

      Article first published online: 27 OCT 2014 | DOI: 10.1002/btpr.1998

  15. Cell Culture and Tissue Engineering

    1. Effects of copper on CHO cells: Cellular requirements and product quality considerations

      Inn H. Yuk, Stephen Russell, Yun Tang, Wei-Ting Hsu, Jacob B. Mauger, Rigzen P. S. Aulakh, Jun Luo, Martin Gawlitzek and John C. Joly

      Article first published online: 24 OCT 2014 | DOI: 10.1002/btpr.2004

  16. Biocatalysts and Bioreactor Design

    1. An effective chemical pretreatment method for lignocellulosic biomass with substituted imidazoles

      Yuzhi Kang, Matthew J. Realff, Minjeong Sohn, Jay H. Lee and Andreas S. Bommarius

      Article first published online: 24 OCT 2014 | DOI: 10.1002/btpr.2005

  17. Cell Culture and Tissue Engineering

    1. Strain engineering to prevent norleucine incorporation during recombinant protein production in Escherichia coli

      Karthik Veeravalli, Michael W. Laird, Mark Fedesco, Yu Zhang and X. Christopher Yu

      Article first published online: 21 OCT 2014 | DOI: 10.1002/btpr.1999

  18. Bioseparations and Downstream Processing

    1. Toward improving selectivity in affinity chromatography with PEGylated affinity ligands: The performance of PEGylated protein A

      José González-Valdez, Alex Yoshikawa, Justin Weinberg, Jorge Benavides, Marco Rito-Palomares and Todd M. Przybycien

      Article first published online: 18 OCT 2014 | DOI: 10.1002/btpr.1994

  19. Cell Culture and Tissue Engineering

    1. Bacterial community structure of a lab-scale anammox membrane bioreactor

      Alejandro Gonzalez-Martinez, F. Osorio, Alejandro Rodriguez-Sanchez, Maria Victoria Martinez-Toledo, Jesus Gonzalez-Lopez, Tommaso Lotti and M. C. M. van Loosdrecht

      Article first published online: 18 OCT 2014 | DOI: 10.1002/btpr.1995

  20. Bioseparations and Downstream Processing

  21. Cell Culture and Tissue Engineering

    1. Soluble production and function of vascular endothelial growth factor/basic fibroblast growth factor complex peptide

      Qing Zhang, Xuejun Lao, Jianhua Huang, Zhongsong Zhu, Lei Pang, Yong Tang, Qifang Song, Jiangfang Huang, Jie Deng, Ning Deng, Qin Yang, Aditi M. Sengupta and Likuan Xiong

      Article first published online: 9 OCT 2014 | DOI: 10.1002/btpr.1997

  22. Bioseparations and Downstream Processing

  23. Formulation and Engineering of Biomaterials

  24. Process Sensing and Control

  25. Applied Cellular Physiology and Metabolic Engineering

  26. Bioseparations and Downstream Processing

    1. In situ cell retention of a CHO culture by a reverse-flow diafiltration membrane bioreactor

      Kristina Meier, Suzana Djeljadini, Lars Regestein, Jochen Büchs, Frederike Carstensen, Matthias Wessling, Tanja Holland and Nicole Raven

      Article first published online: 18 SEP 2014 | DOI: 10.1002/btpr.1988

  27. Process Sensing and Control

    1. Maximizing recombinant human serum albumin production in a Muts Pichia pastoris strain

      Muralidhar Mallem, Shannon Warburton, Fang Li, Ishaan Shandil, Adam Nylen, Sehoon Kim, Youwei Jiang, Michael Meehl, Marc d'Anjou, Terrance A. Stadheim and Byung-Kwon Choi

      Article first published online: 16 SEP 2014 | DOI: 10.1002/btpr.1990

  28. Biocatalysts and Bioreactor Design

    1. Mechanistic modeling of biodiesel production using a liquid lipase formulation

      Jason Price, Björn Hofmann, Vanessa T. L. Silva, Mathias Nordblad, John M. Woodley and Jakob K. Huusom

      Article first published online: 16 SEP 2014 | DOI: 10.1002/btpr.1985

  29. Bioseparations and Downstream Processing

  30. Formulation and Engineering of Biomaterials

  31. Cell Culture and Tissue Engineering

    1. Time efficient way to calculate oxygen transfer areas and power input in cylindrical disposable shaken bioreactors

      Wolf Klöckner, Clemens Lattermann, Franz Pursche, Jochen Büchs, Sören Werner and Dieter Eibl

      Article first published online: 5 SEP 2014 | DOI: 10.1002/btpr.1977

  32. Biocatalysts and Bioreactor Design

    1. Assessment of mass transfer and mixing in rigid lab-scale disposable bioreactors at low power input levels

      Gerco van Eikenhorst, Yvonne E. Thomassen, Leo A. van der Pol and Wilfried A. M. Bakker

      Article first published online: 5 SEP 2014 | DOI: 10.1002/btpr.1981

  33. Bioseparations and Downstream Processing

    1. You have full text access to this OnlineOpen article
      Development and scale-up of a commercial fed batch refolding process for an anti-CD22 two chain immunotoxin

      Thomas Linke, Matthew T. Aspelund, Christopher Thompson, Guoling Xi, Andrew Fulton, Michaela Wendeler, Timothy M. Pabst, Xiangyang Wang, William K. Wang, Kripa Ram and Alan K. Hunter

      Article first published online: 2 SEP 2014 | DOI: 10.1002/btpr.1983

    2. Maximizing binding capacity for protein A chromatography

      Sanchayita Ghose, Jennifer Zhang, Lynn Conley, Ryan Caple, Kevin P. Williams and Douglas Cecchini

      Article first published online: 2 SEP 2014 | DOI: 10.1002/btpr.1980

  34. Biocatalysts and Bioreactor Design

  35. Applied Cellular Physiology and Metabolic Engineering

  36. Cell Culture and Tissue Engineering

    1. Development of small scale cell culture models for screening poloxamer 188 lot-to-lot variation

      Haofan Peng, Kaitlyn M. Hall, Blake Clayton, Kelly Wiltberger, Weiwei Hu, Erik Hughes, John Kane, Rachel Ney and Thomas Ryll

      Article first published online: 19 AUG 2014 | DOI: 10.1002/btpr.1967

    2. Cell culture media supplementation of uncommonly used sugars sucrose and tagatose for the targeted shifting of protein glycosylation profiles of recombinant protein therapeutics

      Patrick Hossler, Sean McDermott, Christopher Racicot, Christopher Chumsae, Haly Raharimampionona, Yu Zhou, David Ouellette, Joseph Matuck, Ivan Correia, John Fann and Jianmin Li

      Article first published online: 19 AUG 2014 | DOI: 10.1002/btpr.1968

    3. The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes

      Wenjin Xiao, Marie Shinohara, Kikuo Komori, Yasuyuki Sakai, Hitoshi Matsui and Tomoharu Osada

      Article first published online: 8 AUG 2014 | DOI: 10.1002/btpr.1954

  37. Bioseparations and Downstream Processing

    1. You have full text access to this OnlineOpen article
    2. Gel filtration chromatography as a method for removing bacterial endotoxin from antibody preparations

      Anne Serdakowski London, Kasey Mackay, Michael Lihon, Yaqin He and Busola Ruth Alabi

      Article first published online: 7 AUG 2014 | DOI: 10.1002/btpr.1961

    3. Understanding and modeling alternating tangential flow filtration for perfusion cell culture

      William Kelly, Jennifer Scully, Di Zhang, Gang Feng, Mathew Lavengood, Jason Condon, John Knighton and Ravinder Bhatia

      Article first published online: 6 AUG 2014 | DOI: 10.1002/btpr.1953

    4. Development of a novel affinity chromatography resin for platform purification of lambda fabs

      Nora Eifler, Giovanni Medaglia, Oliver Anderka, Linus Laurin and Pim Hermans

      Article first published online: 6 AUG 2014 | DOI: 10.1002/btpr.1958

  38. Cell Culture and Tissue Engineering

    1. Synchronized mammalian cell culture: Part I—A physical strategy for synchronized cultivation under physiological conditions

      Oscar Platas Barradas, Uwe Jandt, Max Becker, Janina Bahnemann, Ralf Pörtner and An-Ping Zeng

      Article first published online: 29 JUL 2014 | DOI: 10.1002/btpr.1944

    2. Methodological strategies for transgene copy number quantification in goats (Capra hircus) using real-time PCR

      Ribrio I. T. P. Batista, Maria C. S. Luciano, Dárcio I. A. Teixeira, Vicente J. F. Freitas, Luciana M. Melo, Lyudmila E. Andreeva, Irina A. Serova and Oleg L. Serov

      Article first published online: 26 JUL 2014 | DOI: 10.1002/btpr.1946

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