Biotechnology Progress

Cover image for Vol. 33 Issue 1

Edited By: Michael M. Domach

Impact Factor: 2.167

ISI Journal Citation Reports © Ranking: 2015: 34/125 (Food Science & Technology); 77/161 (Biotechnology & Applied Microbiology)

Online ISSN: 1520-6033

Associated Title(s): AIChE Journal, Bioengineering & Translational Medicine, Environmental Progress & Sustainable Energy, Process Safety Progress

Author Guidelines

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Permission form
Manuscript Preparation: Sample Article
LaTeX Template

Author Guidelines


Biotechnology Progress , an official, bimonthly publication of the American Institute of Chemical Engineers and its technological community, the Society for Biological Engineering, features peer-reviewed research articles, reviews, and descriptions of emerging techniques for the development and design of new processes, products, and devices for the biotechnology, biopharmaceutical and bioprocess industries.

Topical areas of interest include application of biological and engineering principles in fields such as applied cellular physiology and metabolic engineering, biocatalysis and bioreactor design, bioseparations and downstream processing, cell culture and tissue engineering, biosensors and process control, bioinformatics and systems biology, biomaterials and artificial organs, stem cell biology and genetics, and plant biology and food science. Manuscripts concerning the design of related processes, products, or devices are also encouraged. Four types of manuscripts are published in Biotechnology Progress: Research articles, Topical or Review Papers, Letters to the Editor, and Notes. Papers will be accepted for review only if they are not under consideration by another journal.

All authors should read the AIChE Ethical Guidelines and AIChE Code of Ethics.

Types of Manuscripts

Research Articles are full-length expositions of extensive and significant experimental or theoretical studies.

Topical or Review Papers are short reviews or full reviews focused on areas of interest to readers of the journal. They may also be state-of-the-art reports or commentaries. These papers are peer reviewed and are accepted on the basis of technical accuracy, importance, and readability.

Notes are generally eight (or fewer) double-spaced typewritten pages including figures and tables.

Submission of Manuscripts

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published work

Cross Check

Submit your manuscript online at  

Please submit your manuscript as a Word or rtf file (for text and tables) and tiff or eps (for figures). Other file types are not suitable for production. Text, tables, and figures will need to be uploaded individually.

New in 2013: Single file submissions for review: The editorial office of Biotechnology Progress now permits manuscripts to be submitted as a single Word file with figures and tables embedded in the text. Only initial submissions will be permitted in this format; revisions must adhere to the manuscript submission guidelines described in the paragraph above.

LATeX Users: All files must be formatted in LaTeX version 2.02 or earlier. Figures must be formatted as either .tif or .eps files and saved separately. Directory structures should not be used when referencing external files. This will cause a corrupted upload into ScholarOne Manuscripts and will result in the cancellation of manuscript submission. Class and style files may be either internal or external. ScholarOne Manuscripts provides all standard LaTeX class files for author use; however, you may create your own. Please be sure to check the log file provided at submission to see if you are missing the class file from your document.

New in 2013: If your manuscript contains biomass pretreatment research, please complete this document and include with your manuscript submission as either an additional figure in your manuscript or as supplementary material. If choosing to include as supplementary material, save the document in Microsoft Word version 2007 or older. When uploading this file to ScholarOne Manuscripts, please designate as a "Supplementary Material for Review" file.

For technical assistance, please contact

If you have any questions about the online submission process, you may also contact the Biotechnology Progress Editorial Office:

Elizabeth Gillard, Ph.D. Biotechnology Progress Editorial Office Email:

Manuscript Preparation

Cover Letter

A cover letter should accompany each submitted manuscript. The letter should provide the corresponding author’s name, postal and e-mail addresses, and telephone and fax numbers.

The letter should address the significance of the manuscript and provide a list of 3-5 key words. Authors are also urged to provide the names and email addresses of recommended reviewers.

All editorial correspondence concerning receipt, status, review, revision, and publication of manuscripts will be sent only to one person who has been assigned as the “corresponding author” during the evaluation period. The corresponding author is responsible for communicating the manuscript status to all coauthors of the paper.

Conflict of Interest Disclosure.  Biotechnology Progress and Wiley require that all authors disclose any potential sources of conflict of interest. Any interest or relationship, financial or otherwise, that might be perceived as influencing an author's objectivity is considered a potential source of conflict of interest. These must be disclosed when directly relevant or indirectly related to the work that the authors describe in their manuscript. Potential sources of conflict include but are not limited to patent or stock ownership, membership of a company board of directors, membership of an advisory board or committee for a company, and consultancy for or receipt of speaker’s fees from a company. The existence of a conflict of interest does not preclude publication in this journal.

 If the authors have no conflict of interest to declare, they must also state this at submission.

 It is the responsibility of the corresponding author to review this policy with all authors and to collectively list in the cover letter to the Editor, in the manuscript (under the Acknowledgments section), and in the online submission system ALL pertinent commercial and other relationships.

Title. The title should accurately, clearly, and concisely reflect the emphasis and content of the paper. The title must be brief and grammatically correct.

Author List. Use first names, initials, and surnames. At least one author must be designated as the author to whom correspondence should be addressed and email information should be provided.

Address. The affiliation(s) listed should be the institution(s) where the work was conducted. If the present address of an author differs from that at which the work was done, the current address should be given in a footnote.

Abstract. All manuscripts must contain a short abstract (no more than 250 words), which should briefly state the reason for the work, the significant results, and the conclusions.

Text. The first paragraphs should explain what the motivation and import of the work are, where it fits in the development of the field, and perhaps why it should be of interest to researchers in other areas. The addition of a Conclusion section at the end of the paper, which briefly summarizes the principal findings of the work, is recommended.

Acknowledgments. Dedications and notes acknowledging financial assistance, thesis work, or oral presentations at a scientific meeting or conference should be brief and placed in the Acknowledgment section.

Notation. It is not necessary if all symbols were defined in the text. This section should be placed at the end of the text and immediately before the Literature Cited section. Symbols cited should be listed alphabetically in the order of Roman symbols, letters, subscripts and superscripts

Figures. All figures must be mentioned in the text in consecutive order and be numbered with Arabic numerals. A caption giving the figure number and a brief description, preferably only one or two sentences must be included with each figure. The caption should be understandable without reference to the text.

Tables. Tables should be numbered consecutively with Arabic numerals. Each table must have a brief title that describes its contents. The title should be understandable without reference to the text. Details should be put in footnotes, not in the title. Tables should be used when the data cannot be presented clearly as narrative, when many precise numbers must be presented or when more meaningful interrelationships can be conveyed by the tabular format. Tables should supplement, not duplicate, information presented in the text and figures. Tables should be simple and concise. Footnotes in tables should be given letter designations and be cited in the table by italic superscript letters. The sequence of letters should proceed by row rather than by column. In setting up tables, authors should keep in mind the type area of the Biotechnology Progress page (17.8 - 25.0 cm) and the column width (8.5 cm) and should make tables conform to the limitations of these dimensions.

Literature Cited

Literature Cited should be formatted according to the AMA style, and must be listed numerically in the order they are cited in the text. Authors will need to provide complete information for each citation, as shown in typical examples below.


1. Wang X, Da Silva NA. Estimation of the rate of cloned gene integration via retrotransposition. Biotechnol Prog. 1997;13:123-131.

2. Cain K, Peters S, Hailu H, Sweeney B, Stephens P, Heads J, Sarkar K, Ventom A, Page C, Dickson A. A CHO cell line engineered to express XBPl and EROl-Lα has increased levels of transient protein expression [published online ahead of print January 19, 2013]. Biotechnol Prog. doi: 10.1002/btpr.1693.


3. Givan AL. Flow cytometry: first principles (2nd edition). New York:John Wiley & Sons, Inc., 2001.

Book Chapter:

4. Luketich JD, Ginsberg RJ. Diagnosis and staging of lung cancer.In:Johnson BE, Johnson DH. Lung cancer. New York: Wiley-Liss, Inc.,1995:161-73.


5. Zotin JLZ. Caracterização experimental do escoamento no interior de uma válvula ciclônica. MSc Thesis. MSc Thesis. COPPE, Universidade Federal do Rio de Janeiro, Brazil; 2010.

6. Vallez-Chetreanu F. Characterization of the mechanism of action of spin-filters for animal cell. PhD Thesis. École Polytechnique Fédérale de Lausanne, Switzerland; 2006.

Online source:

7. Environmental Protection Agency. Proposed Regulations to address water pollution from concentrated animal feeding operations. Environmental Protection Agency. Available at: March, 2001. Accessed August 18, 2010.


8. Trung Bui-Khac ND. Process for extraction and purification of paclitaxel from natural sources. U.S. Patent 6,452,024, 2002

For a sample article with correct formatting for Literature Cited, click here.

Topical Areas and Key Words

Select the heading from the six topical areas listed in the ScholarOne Manuscripts pull down menu under the Table of Contents Section.   (The topical areas are described in the Aims and Scope section of the journal under Overview.) Provide a minimum of two and a maximum of five key words that best capture the concepts and scope of the work.

Graphics Preparation

All illustration files should be in TIFF or EPS formats. Do not submit native application formats.

Journal quality reproduction requires the following minimum resolution standards:

grey scale files            600 dpi to 1200 dpi

color files                     300dpi

Supporting Information

Biotechnology Progress authors can publish supporting information online in Wiley Online Library. Supporting Information may include (but is not limited to) video clips, large sections of tabular data, program code, or electronic graphical files. Supplementary material must be included with the initial manuscript submission so that it is available for peer review.

Search Engine Optimization for Your Article

Consult our SEO Tips for Authors page in order to maximize online discoverability for your published research. Included are tips for making your title and abstract SEO-friendly, choosing appropriate keywords, and promoting your research through social media. 

Copyright/License Agreements

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement:

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:
CTA Terms and Conditions

For authors choosing OnlineOpen:

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:

For RCUK and Wellcome Trust authors click on the link below to preview the terms and conditions of this license:
Creative Commons Attribution License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

Additional Reprint Purchases

Should you wish to purchase additional copies of your article, please follow the instructions provided at:

Permission for Reproduction

It is the Author's responsibility to obtain written permission to reproduce material that has appeared in another publication.

Author Services - Online production tracking is now available for your article through Wiley-Blackwell's Author Services. Author Services enables authors to track their article - once it has been accepted - through the production process to publication online and in print. Authors can check the status of articles online and choose to receive automated emails at key stages of production. The author will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit our Author Services

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