Journal of Neurochemistry

Cover image for Vol. 130 Issue 3

Edited By: Jörg Schulz

Impact Factor: 3.973

ISI Journal Citation Reports © Ranking: 2012: 71/252 (Neurosciences); 83/290 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. Leptin inhibits amyloid β-protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway

    Naoki Yamamoto, Mamoru Tanida, Rika Kasahara, Kazuya Sobue and Kenji Suzuki

    Accepted manuscript online: 21 JUL 2014 02:25AM EST | DOI: 10.1111/jnc.12828

  2. Stimulatory role of the chemokine CCL2 in the migration and peptide expression of embryonic hypothalamic neurons

    Kinning Poon, Hui Tin Ho, Jessica R. Barson and Sarah F. Leibowitz

    Accepted manuscript online: 21 JUL 2014 02:25AM EST | DOI: 10.1111/jnc.12827

  3. Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein

    Nicola J. Rutherford, Brenda D. Moore, Todd E. Golde and Benoit I. Giasson

    Article first published online: 21 JUL 2014 | DOI: 10.1111/jnc.12806

    Thumbnail image of graphical abstract

    The α-synuclein (SNCA) mutations, H50Q and G51D, cause Parkinson's disease. We found that H50Q increases and G51D decreases the rate of α-synuclein aggregation in vitro, and cells over-expressing the mutant proteins show decreased viability when stressed, compared to wild type. G51D is the first SNCA mutation to show decreased α-synuclein aggregation, suggesting a distinct disease mechanism to other SNCA mutations.

  4. Characterization of [3H]LS-3-134, a Novel Arylamide Phenylpiperazine D3 Dopamine Receptor Selective Radioligand

    Claudia Rangel-Barajas, Maninder Malik, Michelle Taylor, Kim A. Neve, Robert H. Mach and Robert R. Luedtke

    Accepted manuscript online: 18 JUL 2014 10:33AM EST | DOI: 10.1111/jnc.12825

  5. Brain Serotonin Synthesis in MDMA (Ecstasy) Polydrug Users: An alpha-[11C]Methyl-L-tryptophan Study

    Linda Booij, Jean-Paul Soucy, Simon N. Young, Martine Regoli, Paul Gravel, Mirko Diksic, Marco Leyton, Robert O. Pihl and C Benkelfat

    Accepted manuscript online: 18 JUL 2014 10:33AM EST | DOI: 10.1111/jnc.12826

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