Journal of Neurochemistry

Cover image for Vol. 133 Issue 1

Edited By: Jörg Schulz

Impact Factor: 4.244

ISI Journal Citation Reports © Ranking: 2013: 63/252 (Neurosciences); 74/291 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. Vinexin-β deficiency protects against cerebral ischaemia/reperfusion injury by inhibiting neuronal apoptosis

    Mingchang Li, Sen Guo, Peng Zhang, Jun Gong, Ankang Zheng, Yan Zhang and Hongliang Li

    Accepted manuscript online: 30 MAR 2015 10:27PM EST | DOI: 10.1111/jnc.13110

  2. The role of parkinson's disease-associated receptor gpr37 in the hippocampus: functional interplay with the adenosinergic system

    João P. Lopes, Xavier Morató, Carolina Souza, Cindy Pinhal, Nuno J. Machado, Paula M. Canas, Henrique B. Silva, Igor Stagljar, Jorge Gandía, Víctor Fernández-Dueñas, Rafael Luján, Rodrigo A. Cunha and Francisco Ciruela

    Accepted manuscript online: 30 MAR 2015 10:25PM EST | DOI: 10.1111/jnc.13109

  3. Development of mature BDNF-specific sandwich ELISA

    Yoon Lim, Jin-Hua Zhong and Xin-Fu Zhou

    Accepted manuscript online: 30 MAR 2015 08:58PM EST | DOI: 10.1111/jnc.13108

  4. Kisspeptin1 modulates odorant-evoked fear response via two serotonin receptor subtypes (5-HT1A and 5-HT2) in zebrafish

    Fatima M. Nathan, Satoshi Ogawa and Ishwar S. Parhar

    Accepted manuscript online: 28 MAR 2015 09:38AM EST | DOI: 10.1111/jnc.13105

  5. Neuroprotective effects of vildagliptin in rat rotenone Parkinson's disease model: role of RAGE-NFκB and Nrf2-antioxidant signaling pathways

    Rania M. Abdelsalam and Marwa M. Safar

    Article first published online: 26 MAR 2015 | DOI: 10.1111/jnc.13087

    Thumbnail image of graphical abstract

    In the rat rotenone model of Parkinson's disease (PD), striatal RAGE/NFκB signaling was up-regulated associated with elevated levels of inflammatory, oxidative stress, and apoptotic mediators resulting in dopaminergic neurons death and hence motor impairment. Vildagliptin, a dipeptidyl peptidase (DPP)-4 inhibitor, blocked the RAGE/NFκB cascade exerting a potential antiparkinsonian effect. RAGE, receptor for advanced glycation end product; NFκB, nuclear factor κB; TNFα, tumor necrosis factor alpha; ICAM, intracellular adhesion molecule; iNOS, inducible nitric oxide synthase; MPO, myeloperoxidase.