Journal of Neurochemistry

Cover image for Vol. 125 Issue 5

Edited By: Jörg Schulz

Impact Factor: 4.061

ISI Journal Citation Reports © Ranking: 2011: 59/244 (Neurosciences); 77/290 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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  • Current Issue:June 2013

    Volume 125, Issue 5

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    Volume 125, Issue 3

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    Volume 125, Issue 2

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    Volume 125, Issue Supplement s1

    Special Issue: The 24th Biennial Meeting of the In...

Pre-clinical Systematic Reviews

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Recently Published Articles

  1. Native STIM2 and ORAI1 proteins form a calcium-sensitive and thapsigargin-insensitive complex in cortical neurons

    Joanna Gruszczynska-Biegala and Jacek Kuznicki

    Accepted manuscript online: 25 MAY 2013 06:56AM EST | DOI: 10.1111/jnc.12320

  2. Neuroprotective effects of donepezil against Aβ42-induced neuronal toxicity are mediated through not only enhancing PP2A activity, but also regulating GSK-3β and nAChRs activity

    Min-Young Noh, Seong Ho Koh, Sung-Min Kim, Tangui Maurice, Sae-Kwang Ku and Seung Hyun Kim

    Accepted manuscript online: 25 MAY 2013 06:09AM EST | DOI: 10.1111/jnc.12319

  3. The role of tetrahydrobiopterin and catecholamines in the developmental regulation of tyrosine hydroxylase level in the brain

    Daigo Homma, Setsuko Katoh, Hirofumi Tokuoka and Hiroshi Ichinose

    Article first published online: 22 MAY 2013 | DOI: 10.1111/jnc.12287

    Thumbnail image of graphical abstract

    Tetrahydrobiopterin (BH4) is an essential cofactor of tyrosine hydroxylase (TH). We found that BH4 and dopa administration in infancy restored the loss of TH protein caused by BH4 deficiency and that the effects of these treatments are attenuated in young adulthood. These findings indicate that the post-natal augmentation of TH protein requires catecholamines and suggest that there is a critical period for the dopaminergic development.

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    Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

    Peter Penzes, Andres Buonanno, Maria Passafaro, Carlo Sala and Robert A. Sweet

    Article first published online: 22 MAY 2013 | DOI: 10.1111/jnc.12261

  5. Involvement of α2-antiplasmin in dendritic growth of hippocampal neurons

    Eri Kawashita, Yosuke Kanno, Haruka Asayama, Kiyotaka Okada, Shigeru Ueshima, Osamu Matsuo and Hiroyuki Matsuno

    Article first published online: 22 MAY 2013 | DOI: 10.1111/jnc.12281

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    The α2-Antiplasmin (α2AP) protein regulates cellular functions independently or dependently of plasmin, and is highly expressed in the hippocampus. However, the role of α2AP was unclear. Here, we first report that α2AP induces dendritic growth in hippocampal neurons through p38 MAPK activation, independent of plasmin, providing new insights into the role of α2AP in the CNS.

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