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Cancer Science

Cover image for Vol. 107 Issue 4

Edited By: Yusuke Nakamura

Impact Factor: 3.523

ISI Journal Citation Reports © Ranking: 2014: 73/211 (Oncology)

Online ISSN: 1349-7006

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MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting mitofusin-2
Xiaohu Zhou, Linshi Zhang, et al.

Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer
Yumiko Kiyohara, Kiyoshi Yoshino, et al.

Role of hemoglobin and transferrin in multi-wall carbon nanotube-induced mesothelial injury and carcinogenesis
Yue Wang, Yasumasa Okazaki, et al.

Novel combination of serum microRNA for detecting breast cancer in the early stage
Akihiko Shimomura, Sho Shiino, et al.

RAP80 regulates epithelial–mesenchymal transition related with metastasis and malignancy of cancer
Song Yi Park, Sovannarith Korm, et al.

Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis
Hosne Ara, Maki Takagishi, et al.

Timosaponin AIII inhibits melanoma cell migration by suppressing COX-2 and in vivo tumor metastasis
Ki Mo Kim, A-Rang Im, et al.

Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145–ZEB1/2–FSCN1 pathway
Mei Xue, Huan Pang, et al.

Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations
Ken Suzawa, Shinichi Toyooka, et al.

2015 Guidance on cancer immunotherapy development in early-phase clinical studies

XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma
Jingjing Cheng, Weiran Liu, et al.

DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer
Kota Ouchi, Shin Takahashi, et al.

Retinoid X receptor α enhances human cholangiocarcinoma growth through simultaneous activation of Wnt/β-catenin and nuclear factor-κB pathways
Gui-Li Huang, Wei Zhang, Hong-Yue Ren, et al.

Abnormal expression of miR-1 in breast carcinoma as a potent prognostic factor
Hiroyuki Minemura, Kiyoshi Takagi, et al.

DDX5 promotes proliferation and tumorigenesis of non-small-cell lung cancer cells by activating β-catenin signaling pathway
Zhendong Wang, Zhonghua Luo, et al.

STX11functions as a novel tumor suppressor gene in peripheral T-cell lymphomas
Noriaki Yoshida, Shinobu Tsuzuki, et al.

Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice
Hikari Okada, Masao Honda, et al.

Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential
Azusa Yamato, Manabu Soda, et al.

A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B
Hiroshi I. Suzuki, Akihiro Katsura, et al.

Smoking and survival after breast cancer diagnosis in Japanese women: A prospective cohort study
Yoichiro Kakugawa, Masaaki Kawai, et al.

Novel Aurora/vascular endothelial growth factor receptor dual kinase inhibitor as treatment for hepatocellular carcinoma
Keisuke Nakao, Shinji Tanaka, et al.

Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells
Shuhei Hakiri, Hirotaka Osada, et al.

Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK–MMP–laminin5γ2 signaling pathway
Xiao Liu, Ji-Hui Wang, et al.

Open access


Dysregulation of protein methyltransferases in human cancer: An emerging target class for anticancer therapy
Ryuji Hamamoto and Yusuke Nakamura

Extracellular vesicle transfer of cancer pathogenic components
Yu Fujita, Yusuke Yoshioka, et al.

Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways
Kanae Echizen, Osamu Hirose, et al.

Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies
Noura Choudhury and Yusuke Nakamura

Therapeutic strategies targeting cancer stem cells
Go J. Yoshida and Hideyuki Saya

Immune responses to human cancer stem-like cells/cancer-initiating cells
Yoshihiko Hirohashi, Toshihiko Torigoe, et al.

Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis
Masato Enomoto, John Vaughen, et al.

Adjuvant for vaccine immunotherapy of cancer – focusing on Toll-like receptor 2 and 3 agonists for safely enhancing antitumor immunity
Tsukasa Seya, Hiroaki Shime, et al.

Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
Yoshiko Maida and Kenkichi Masutomi

Induced pluripotent stem cell technology for dissecting the cancer epigenome
Katsunori Semi and Yasuhiro Yamada

Potential clinical application of interleukin-27 as an antitumor agent
Takayuki Yoshimoto, Yukino Chiba, et al.

Immune checkpoint blockade opens an avenue of cancer immunotherapy with a potent clinical efficacy
Keishi Adachi and Koji Tamada

Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype
Naohide Oue, Kazuhiro Sentani, et al.

Exosomes in development, metastasis and drug resistance of breast cancer
Dan-dan Yu, Ying Wu, et al.

In vivogene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression
Miki Kamiyama, Isao Naguro, et al.

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor
Hideyo Hirai, Asumi Yokota, et al.

Nestin as a marker of cancer stem cells
Jakub Neradil and Renata Veselska

A meta-analysis of mammographic screening with and without clinical breast examination
Chisato Hamashima, Koji Ohta, et al.

Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
Eishi Ashihara, Tetsuya Takada, et al.