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Cancer Science

Cover image for Vol. 105 Issue 12

Edited By: Yusuke Nakamura

Impact Factor: 3.534

ISI Journal Citation Reports © Ranking: 2013: 68/203 (Oncology)

Online ISSN: 1349-7006

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Increased Impact Factor 3.534 !
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Open AccessWe are pleased to announce that all articles published by Cancer Science are now freely available to read, download and share. To cover the cost of publishing, a publication fee will be charged. Please refer to the article publication charges page for more details.

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Open access

Cancer_Science_Highlight_Articles

Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase–phosphoinositide 3-kinase-dependent anti-apoptotic signaling
Haruki Horiguchi, Motoyoshi Endo, et al.

Silencing of STRN4 suppresses the malignant characteristics of cancer cells
Meihong Wong, Toshinori Hyodo, et al.

Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors
Isao Momose, Hikaru Abe, et al.

Hypoxia-mediated CD24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasion
Nobuaki Fujikuni, Hideki Yamamoto, et al.

Prognostic value of stromal cell-derived factor 1 expression in patients with gastric cancer after surgical resection
Xuefei Wang, Heng Zhang, et al.

Tumor budding in colorectal carcinoma assessed by cytokeratin immunostaining and budding areas: Possible involvement of c-Met
Keisuke Satoh, Satoshi Nimura, et al.

In vivosubcellular imaging of tumors in mouse models using a fluorophore-conjugated anti-carcinoembryonic antigen antibody in two-photon excitation microscopy
Shigehiro Koga, Yusuke Oshima, et al.

Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis
Yoko Takaki, Yoshimasa Saito, et al.

Tumor necrosis factor-α promotes the lymphangiogenesis of gallbladder carcinoma through nuclear factor-κB-mediated upregulation of vascular endothelial growth factor-C
Qiang Du, Lei Jiang, et al.

Expression of platelet-derived growth factor receptor β is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis
Hideki Miyazaki, Yasuhiro Yoshimatsu, et al.

Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation
Hong Qiong Yan, Xiao Bo Huang, et al.

Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis
Atsushi Hamabe, Hirofumi Yamamoto, et al.

Preclinical antitumor activity of S-222611, an oral reversible tyrosine kinase inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2
Hidekazu Tanaka, Michinari Hirata, et al.

In vivoimaging of membrane type-1 matrix metalloproteinase with a novel activatable near-infrared fluorescence probe
Yoichi Shimizu, Takashi Temma, et al.

Newly defined aberrant crypt foci as a marker for dysplasia in the rat colon
Masako Ochiai, Yoshitaka Hippo, et al.

Human epidermal growth factor receptor-2 expression in locally advanced rectal cancer: Association with response to neoadjuvant therapy and prognosis
Xiangjiao Meng, Renben Wang, et al.

Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells
Mari Hosonaga, Yoshimi Arima, et al.

Glabridin attenuates the migratory and invasive capacity of breast cancer cells by activating microRNA-200c
Xianqing Ye, Fei Jiang, et al.

Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinoma
Keiichi Tamai, Mao Nakamura, et al.

LIM protein JUB promotes epithelial–mesenchymal transition in colorectal cancer
Xing-Hua Liang, Guang-Xian Zhang, et al.

Stathmin1 regulates p27 expression, proliferation and drug resistance, resulting in poor clinical prognosis in cholangiocarcinoma
Akira Watanabe, Hideki Suzuki, et al.

Bone resorption facilitates osteoblastic bone metastatic colonization by cooperation of insulin-like growth factor and hypoxia
Takahiro Kuchimaru, Takuya Hoshino, et al.

Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors
Hideki Yamaguchi, Miho Takanashi, et al.

Identification of novel targets for antiangiogenic therapy by comparing the gene expressions of tumor and normal endothelial cells
Tsuguteru Otsubo, Yasuhiro Hida, et al.

Open access

Cancer_Science_Review_Articles

Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability
Masahiro Terasawa, Akira Shinohara, et al.

Molecular mechanisms regulating the hormone sensitivity of breast cancer
Eriko Tokunaga, Yuichi Hisamatsu, et al.

Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways
Timothy H. Ung, Helen J. Madsen, et al.

Safely targeting cancer stem cells via selective catenin coactivator antagonism
Heinz-Josef Lenz and Michael Kahn

Glabridin attenuates the migratory and invasive capacity of breast cancer cells by activating microRNA-200c
Xianqing Ye, Fei Jiang, et al.

Disease-specific mutations in mature lymphoid neoplasms: Recent advances
Mamiko Sakata-Yanagimoto, Terukazu Enami, et al.

Not just gRASping at flaws: Finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers
Hiromichi Ebi, Anthony C. Faber, et al.

Epigenetic dysregulation in glioma
Yutaka Kondo, Keisuke Katsushima, et al.

Targeting DNA damage response in cancer therapy
Noriko Hosoya and Kiyoshi Miyagawa

Gist of Dr. Katsusaburo Yamagiwa's papers entitled “Experimental study on the pathogenesis of epithelial tumors”
Hirota Fujiki

Clinical significance of macrophage heterogeneity in human malignant tumors
iro Komohara, Masahisa Jinushi, et al.

P16INK4A as a surrogate biomarker for human papillomavirus-associated oropharyngeal carcinoma: Consideration of some aspects
Hongzhi Wang, Rui Sun, et al.

Heterogeneity of tumor endothelial cells
Kyoko Hida, Noritaka Ohga, et al.

RETfusion gene: Translation to personalized lung cancer therapy
Takashi Kohno, Koji Tsuta, et al.

Newly developed strategies for improving sensitivity to radiation by targeting signal pathways in cancer therapy
Miao Ding, Erlong Zhang, et al.

Capturing the mammalian Hippo: Elucidating its role in cancer
Miki Nishio, Kohei Otsubo, et al.

Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers
Hazel Tye and Brendan J. Jenkins

Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia
Atsushi Hirao and Takayuki Hoshii

Human T-lymphotropic virus type 1 non-structural proteins: Requirements for latent infection
Risaku Fukumoto

The link between infection and cancer: Tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect
Hiroshi Maeda

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