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Cancer Science

Cover image for Vol. 108 Issue 6

Edited By: Yusuke Nakamura

Impact Factor: 3.974

ISI Journal Citation Reports © Ranking: 2016: 68/217 (Oncology)

Online ISSN: 1349-7006

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Extracellular vesicles as trans-genomic agents: Emerging roles in disease and evolution
Yumi Kawamura, Yusuke Yamamoto, et al.

Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma
Naoya Yamazaki, Yoshio Kiyohara, et al.

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells
Nguyen Duy Sinh, Kaori Endo, et al.

Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy
Shunsuke Chikuma, Mitsuhiro Kanamori, et al.

Identification of FERM domain-containing protein 5 as a novel target of β-catenin/TCF7L2 complex
Chi Zhu, Kiyoshi Yamaguchi, et al.

Mitochondrial uncoupler exerts a synthetic lethal effect against β-catenin mutant tumor cells
Yuki Shikata, Masaki Kiga, et al.

Androgen-induced lncRNA POTEF-AS1 regulates apoptosis-related pathway to facilitate cell survival in prostate cancer cells
Aya Misawa, Ken-ichi Takayama, et al.

Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer
Yuka Inoue, Shoichi Hazama, et al.

Prediction and prioritization of neoantigens: integration of RNA sequencing data with whole-exome sequencing
Takahiro Karasaki, Kazuhiro Nagayama, et al.

Leukemogenic kinase FIP1L1-PDGFRA and a small ubiquitin-like modifier E3 ligase, PIAS1, form a positive cross-talk through their enzymatic activities
Makoto Ibata, Junko Iwasaki, et al.

Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma
Yu Oikawa, Kei-ichi Morita, et al.

Clinicopathological significance of SPC18 in colorectal cancer: SPC18 participates in tumor progression
Takuya Hattori, Kazuhiro Sentani, et al.

NS5ABP37 inhibits liver cancer by impeding lipogenesis and cholesterogenesis
Shenghu Feng, Ming Han, et al.

Amphiregulin triggered epidermal growth factor receptor activation confers in vivo crizotinib-resistance of EML4-ALK lung cancer and circumvention by epidermal growth factor receptor inhibitors
Hirokazu Taniguchi, Shinji Takeuchi, et al.

EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway
Akifumi Endo, Daisuke Tomizawa, et al.

Phase I trial of GBS-01 for advanced pancreatic cancer refractory to gemcitabine
Masafumi Ikeda, Akihiro Sato, et al.

CITED2 in breast carcinoma as a potent prognostic predictor associated with proliferation, migration and chemoresistance
Hiroyuki Minemura, Kiyoshi Takagi, et al.

Upregulation of programmed cell death ligand 1 promotes resistance response in non-small-cell lung cancer patients treated with neo-adjuvant chemotherapy
Panpan Zhang, Yuanyuan Ma, et al.

Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2
Fumihiko Kakizaki, Masahiro Sonoshita, et al.

Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells
Nobuaki Fukushima, Yosuke Minami, et al.

IL-17A-producing CD30+ Vδ1 T cells drive inflammation-induced cancer progression
Yoshitaka Kimura, Nao Nagai, et al.

Unfavorable neuroblastoma prognostic factor NLRR2 inhibits cell differentiation by transcriptional induction through JNK pathway
Afzal Sheikh, Atsushi Takatori, et al.

New mouse model of acute adult T-cell leukemia generated by transplantation of AKT, BCLxL, and HBZ-transduced T cells
Yumiko Kasugai, Noriaki Yoshida, et al.

Pharmacokinetic profiles of significant adverse events with crizotinib in Japanese patients with ABCB1 polymorphism
Yutaka Fujiwara, Akinobu Hamada, et al.

Construction of a disulfide-stabilized diabody against fibroblast growth factor-2 and the inhibition activity in targeting breast cancer
Yaxiong Cai, Jinxia Zhang, et al.

C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility
Yoshie Senda, Naoko Murata-Kamiya, et al.

Myasthenic crisis and polymyositis induced by one dose of nivolumab
Toshihiro Kimura, Satoshi Fukushima, et al.

Negative influence of programmed death-1-ligands on the survival of esophageal cancer patients treated with chemotherapy
Koji Tanaka, Hiroshi Miyata, et al.

Open access


Discovery of Mieap-regulated mitochondrial quality control as a new function of tumor suppressor p53
Yasuyuki Nakamura and Hirofumi Arakawa

Emergence of TNIK inhibitors in cancer therapeutics
Tesshi Yamada and Mari Masuda

Recent advances in genetic modification of adenovirus vectors for cancer treatment
Yuki Yamamoto, Masaki Nagasato, et al.

Oncogenic roles of SMARCB1/INI1 and its deficient tumors
Kenichi Kohashi and Yoshinao Oda

Epigenetics in normal and malignant hematopoiesis: An overview and update 2017
Susumu Goyama and Toshio Kitamura

Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseases
Sugiko Watanabe, Shimpei Kawamoto, et al.

Molecular-targeting therapies against quantitative abnormalities in gene expression with malignant tumors
Toshiyuki Sakai and Yoshihiro Sowa

Tumor-derived spheroids: Relevance to cancer stem cells and clinical applications
Tatsuya Ishiguro, Hirokazu Ohata, et al.

Possible functions of CD169-positive sinus macrophages in lymph nodes in anti-tumor immune responses
Yoshihiro Komohara, Koji Ohnishi, et al.

Hepatocyte growth factor/MET in cancer progression and biomarker discovery
Kunio Matsumoto, Masataka Umitsu, et al.

Antizyme inhibitor 1: a potential carcinogenic molecule
Shiqiao Qiu, Jing Liu, et al.

Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex
Okio Hino and Toshiyuki Kobayashi

Cancer stem cells in human gastrointestinal cancer
Hiroaki Taniguchi, Chiharu Moriya, et al.

Action mechanisms of histone deacetylase inhibitors in the treatment of hematological malignancies
Yoichi Imai, Yoshiro Maru, et al.

Multiple facets of p53 in senescence induction and maintenance
Yoshikazu Johmura and Makoto Nakanishi

Application of glycoscience to the early detection of pancreatic cancer
Eiji Miyoshi and Yoshihiro Kamada