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Cancer Science

Cover image for Vol. 107 Issue 1

Edited By: Yusuke Nakamura

Impact Factor: 3.523

ISI Journal Citation Reports © Ranking: 2014: 73/211 (Oncology)

Online ISSN: 1349-7006

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Open access


Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145–ZEB1/2–FSCN1 pathway
Mei Xue, Huan Pang, et al.

Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations
Ken Suzawa, Shinichi Toyooka, et al.

2015 Guidance on cancer immunotherapy development in early-phase clinical studies

XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma
Jingjing Cheng, Weiran Liu, et al.

DNA methylation status as a biomarker of anti-epidermal growth factor receptor treatment for metastatic colorectal cancer
Kota Ouchi, Shin Takahashi, et al.

Retinoid X receptor α enhances human cholangiocarcinoma growth through simultaneous activation of Wnt/β-catenin and nuclear factor-κB pathways
Gui-Li Huang, Wei Zhang, Hong-Yue Ren, et al.

Abnormal expression of miR-1 in breast carcinoma as a potent prognostic factor
Hiroyuki Minemura, Kiyoshi Takagi, et al.

DDX5 promotes proliferation and tumorigenesis of non-small-cell lung cancer cells by activating β-catenin signaling pathway
Zhendong Wang, Zhonghua Luo, et al.

STX11functions as a novel tumor suppressor gene in peripheral T-cell lymphomas
Noriaki Yoshida, Shinobu Tsuzuki, et al.

Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice
Hikari Okada, Masao Honda, et al.

Oncogenic activity of BIRC2 and BIRC3 mutants independent of nuclear factor-κB-activating potential
Azusa Yamato, Manabu Soda, et al.

A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B
Hiroshi I. Suzuki, Akihiro Katsura, et al.

Smoking and survival after breast cancer diagnosis in Japanese women: A prospective cohort study
Yoichiro Kakugawa, Masaaki Kawai, et al.

Novel Aurora/vascular endothelial growth factor receptor dual kinase inhibitor as treatment for hepatocellular carcinoma
Keisuke Nakao, Shinji Tanaka, et al.

Functional differences between wild-type and mutant-type BRCA1-associated protein 1 tumor suppressor against malignant mesothelioma cells
Shuhei Hakiri, Hirotaka Osada, et al.

Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK–MMP–laminin5γ2 signaling pathway
Xiao Liu, Ji-Hui Wang, et al.

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor
Hideyo Hirai, Asumi Yokota, et al.

EVI1, a target gene for amplification at 3q26, antagonizes transforming growth factor-β-mediated growth inhibition in hepatocellular carcinoma
Kohichiroh Yasui, Chika Konishi, et al.

Adaptor protein CRK induces epithelial–mesenchymal transition and metastasis of bladder cancer cells through HGF/c-Met feedback loop
Ryuji Matsumoto, Masumi Tsuda, et al.

Persistent activation of STAT3 by PIM2-driven positive feedback loop for epithelial-mesenchymal transition in breast cancer
Nizam Uddin, Rae-Kwon Kim, et al.

Expression of ribosome-binding protein 1 correlates with shorter survival in Her-2 positive breast cancer
Xiaoshuan Liang, Shanshan Sun, et al.

Epidermal growth factor receptor and AKT1 gene copy numbers by multi-gene fluorescence in situ hybridization impact on prognosis in breast cancer
Jiao Li, Wei Su, Sheng Zhang, et al.

Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer
Tetsuro Yoshimaru, Masato Komatsu, et al.

Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses
Yasuharu Nishimura, Yusuke Tomita, et al.

Open access


Therapeutic strategies targeting cancer stem cells
Go J. Yoshida and Hideyuki Saya

Immune responses to human cancer stem-like cells/cancer-initiating cells
Yoshihiko Hirohashi, Toshihiko Torigoe, et al.

Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis
Masato Enomoto, John Vaughen, et al.

Adjuvant for vaccine immunotherapy of cancer – focusing on Toll-like receptor 2 and 3 agonists for safely enhancing antitumor immunity
Tsukasa Seya, Hiroaki Shime, et al.

Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
Yoshiko Maida and Kenkichi Masutomi

Induced pluripotent stem cell technology for dissecting the cancer epigenome
Katsunori Semi and Yasuhiro Yamada

Potential clinical application of interleukin-27 as an antitumor agent
Takayuki Yoshimoto, Yukino Chiba, et al.

Immune checkpoint blockade opens an avenue of cancer immunotherapy with a potent clinical efficacy
Keishi Adachi and Koji Tamada

Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype
Naohide Oue, Kazuhiro Sentani, et al.

Exosomes in development, metastasis and drug resistance of breast cancer
Dan-dan Yu, Ying Wu, et al.

In vivogene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression
Miki Kamiyama, Isao Naguro, et al.

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor
Hideyo Hirai, Asumi Yokota, et al.

Nestin as a marker of cancer stem cells
Jakub Neradil and Renata Veselska

A meta-analysis of mammographic screening with and without clinical breast examination
Chisato Hamashima, Koji Ohta, et al.

Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
Eishi Ashihara, Tetsuya Takada, et al.

Epithelial–mesenchymal transition is regulated at post-transcriptional levels by transforming growth factor-β signaling during tumor progression
Masao Saitoh

Intracellular signals of lung cancer cells as possible therapeutic targets
Kiyomichi Tanaka, Keiki Kumano, et al.

Pharmacokinetics, dynamics and toxicity of docetaxel: Why the Japanese dose differs from the Western dose
Hirotsugu Kenmotsu and Yusuke Tanigawara

Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses
Yasuharu Nishimura, Yusuke Tomita, et al.

Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies
Hironori Harada and Yuka Harada

Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects
Yoko Omoto and Hirotaka Iwase

Recent advances in the treatment of adult T-cell leukemia-lymphomas
Atae Utsunomiya, Ilseung Choi, et al.

Radiation signatures in childhood thyroid cancers after the Chernobyl accident: Possible roles of radiation in carcinogenesis
Keiji Suzuki, Norisato Mitsutake, et al.

Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability
Masahiro Terasawa, Akira Shinohara, et al.