You have full text access to this Open Access content

Cancer Science

Cover image for Vol. 106 Issue 5

Edited By: Yusuke Nakamura

Impact Factor: 3.534

ISI Journal Citation Reports © Ranking: 2013: 68/203 (Oncology)

Online ISSN: 1349-7006

Recently Published Issues

See all


Free App for iPhone and iPad is now available
Download the App today

Increased Impact Factor 3.534 !
Read, cite the journal, or submit your paper to keep contributing to the success of Cancer Science.
Click here to access the TOP cited articles published in 2013-2014.


Open AccessWe are pleased to announce that all articles published by Cancer Science are now freely available to read, download and share. To cover the cost of publishing, a publication fee will be charged. Please refer to the article publication charges page for more details.

For inquires, contact

Open access


Epidermal growth factor receptor and AKT1 gene copy numbers by multi-gene fluorescence in situ hybridization impact on prognosis in breast cancer
Jiao Li, Wei Su, Sheng Zhang, et al.

Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer
Tetsuro Yoshimaru, Masato Komatsu, et al.

Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses
Yasuharu Nishimura, Yusuke Tomita, et al.

NeuroD1 promotes neuroblastoma cell growth by inducing the expression of ALK
Fangjin Lu, Satoshi Kishida, et al.

Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells
Takayuki Takachi, Masahiko Takahashi, et al.

Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation
Rajeev Mishra, Takayoshi Watanabe, et al.

Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation
Masato Nakaguro, Shinichi Kiyonari, et al.

Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells
Yukiko Aikawa, Kazutsune Yamagata, et al.

Myeloid heme oxygenase-1 promotes metastatic tumor colonization in mice
Heng-Huei Lin, Ming-Tsai Chiang, et al.

TAZ regulates cell proliferation and epithelial–mesenchymal transition of human hepatocellular carcinoma
Heng Xiao, Ning Jiang, et al.

Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors
Ken Saijo, Jin Imamura, et al.

Sunitinib impedes brain tumor progression and reduces tumor-induced neurodegeneration in the microenvironment
Gökçe Hatipoglu, Stefan W. Hock, et al.

Receptor activator for nuclear factor-κB ligand signaling promotes progesterone-mediated estrogen-induced mammary carcinogenesis
Thiyagarajan Boopalan, Arunkumar Arumugam, et al.

Prognostic significance of promyelocytic leukemia expression in gastrointestinal stromal tumor; integrated proteomic and transcriptomic analysis
Hiroshi Ichikawa, Akihiko Yoshida, et al.

Therapeutic activity of glycoengineered anti-GM2 antibodies against malignant pleural mesothelioma
Qi Li, Wei Wang, et al.

Angiopoietin-like protein 2 renders colorectal cancer cells resistant to chemotherapy by activating spleen tyrosine kinase–phosphoinositide 3-kinase-dependent anti-apoptotic signaling
Haruki Horiguchi, Motoyoshi Endo, et al.

Silencing of STRN4 suppresses the malignant characteristics of cancer cells
Meihong Wong, Toshinori Hyodo, et al.

Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors
Isao Momose, Hikaru Abe, et al.

Hypoxia-mediated CD24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasion
Nobuaki Fujikuni, Hideki Yamamoto, et al.

Prognostic value of stromal cell-derived factor 1 expression in patients with gastric cancer after surgical resection
Xuefei Wang, Heng Zhang, et al.

Tumor budding in colorectal carcinoma assessed by cytokeratin immunostaining and budding areas: Possible involvement of c-Met
Keisuke Satoh, Satoshi Nimura, et al.

In vivosubcellular imaging of tumors in mouse models using a fluorophore-conjugated anti-carcinoembryonic antigen antibody in two-photon excitation microscopy
Shigehiro Koga, Yusuke Oshima, et al.

Silencing of microRNA-122 is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis
Yoko Takaki, Yoshimasa Saito, et al.

Open access


Epithelial–mesenchymal transition is regulated at post-transcriptional levels by transforming growth factor-β signaling during tumor progression
Masao Saitoh

Intracellular signals of lung cancer cells as possible therapeutic targets
Kiyomichi Tanaka, Keiki Kumano, et al.

Pharmacokinetics, dynamics and toxicity of docetaxel: Why the Japanese dose differs from the Western dose
Hirotsugu Kenmotsu and Yusuke Tanigawara

Cancer immunotherapy using novel tumor-associated antigenic peptides identified by genome-wide cDNA microarray analyses
Yasuharu Nishimura, Yusuke Tomita, et al.

Recent advances in myelodysplastic syndromes: Molecular pathogenesis and its implications for targeted therapies
Hironori Harada and Yuka Harada

Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects
Yoko Omoto and Hirotaka Iwase

Recent advances in the treatment of adult T-cell leukemia-lymphomas
Atae Utsunomiya, Ilseung Choi, et al.

Radiation signatures in childhood thyroid cancers after the Chernobyl accident: Possible roles of radiation in carcinogenesis
Keiji Suzuki, Norisato Mitsutake, et al.

Double-strand break repair-adox: Restoration of suppressed double-strand break repair during mitosis induces genomic instability
Masahiro Terasawa, Akira Shinohara, et al.

Molecular mechanisms regulating the hormone sensitivity of breast cancer
Eriko Tokunaga, Yuichi Hisamatsu, et al.

Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways
Timothy H. Ung, Helen J. Madsen, et al.

Safely targeting cancer stem cells via selective catenin coactivator antagonism
Heinz-Josef Lenz and Michael Kahn

Glabridin attenuates the migratory and invasive capacity of breast cancer cells by activating microRNA-200c
Xianqing Ye, Fei Jiang, et al.

Disease-specific mutations in mature lymphoid neoplasms: Recent advances
Mamiko Sakata-Yanagimoto, Terukazu Enami, et al.

Not just gRASping at flaws: Finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers
Hiromichi Ebi, Anthony C. Faber, et al.

Epigenetic dysregulation in glioma
Yutaka Kondo, Keisuke Katsushima, et al.

Targeting DNA damage response in cancer therapy
Noriko Hosoya and Kiyoshi Miyagawa

Gist of Dr. Katsusaburo Yamagiwa's papers entitled “Experimental study on the pathogenesis of epithelial tumors”
Hirota Fujiki

Clinical significance of macrophage heterogeneity in human malignant tumors
Yoshihiro Komohara, Masahisa Jinushi, et al.

P16INK4A as a surrogate biomarker for human papillomavirus-associated oropharyngeal carcinoma: Consideration of some aspects
Hongzhi Wang, Rui Sun, et al.

Heterogeneity of tumor endothelial cells
Kyoko Hida, Noritaka Ohga, et al.

RETfusion gene: Translation to personalized lung cancer therapy
Takashi Kohno, Koji Tsuta, et al.