Alimentary Pharmacology & Therapeutics

FREE Readers Choice: Top Downloads 2012

Hepatology

Review article: chronic hepatitis B – anti-viral or immunomodulatory therapy?

Review article: current antiviral therapy of chronic hepatitis B

UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

Review article: drug-induced liver injury – its pathophysiology and evolving diagnostic tools

Systematic review: the diagnosis and staging of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

Inflammatory Bowel Disease

Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient

Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease

Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease

Review article: infliximab for Crohn’s disease treatment – shifting therapeutic strategies after 10 years of clinical experience

Functional Disorders

Review article: probiotics for the treatment of irritable bowel syndrome – focus on lactic acid bacteria

Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life –– a double-blind, placebo-controlled study

Review article: the treatment of functional abdominal bloating and distension

Review article: the functional abdominal pain syndrome

Review article: current treatment options and management of functional dyspepsia

Systematic review: cardiovascular safety profile of 5-HT4 agonists developed for gastrointestinal disorders

Other

Review article: coeliac disease, new approaches to therapy

Systematic review: the use of proton pump inhibitors and increased susceptibility to enteric infection