British Journal of Clinical Pharmacology

Cover image for Vol. 81 Issue 6

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: A.F. Cohen (Editor-in-Chief), A. de Boer (European Editor), A. Ferro (Reviews Editor), A. Gilchrist (Online Editor), G. Isbister (Australasian Editor), S. Ross (Education Editor) and A. Webb (European Editor)

Impact Factor: 3.878

ISI Journal Citation Reports © Ranking: 2014: 46/255 (Pharmacology & Pharmacy)

Online ISSN: 1365-2125

Associated Title(s): British Journal of Pharmacology, Pharmacology Research & Perspectives


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  1. Reviews

    1. Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy

      Linda Gabrielsson, Sofia Mattsson and Christopher J. Fowler

      Accepted manuscript online: 24 MAY 2016 05:05PM EST | DOI: 10.1111/bcp.13020

  2. Drug Safety

    1. Risk of venous thromboembolism in cancer patients treated with epoetins or blood transfusions

      Antonios Douros, Kathrin Jobski, Bianca Kollhorst, Tania Schink, Edeltraut Garbe and (AD, KJ: joint first authors)

      Accepted manuscript online: 20 MAY 2016 07:45PM EST | DOI: 10.1111/bcp.13019

  3. Systematic Reviews

    1. A Literature Review on Pharmacological Sensitivity of Human Evoked Hyperalgesia Pain Models

      G. van Amerongen, M. W. de Boer, G. J. Groeneveld and J. L. Hay

      Accepted manuscript online: 20 MAY 2016 09:05AM EST | DOI: 10.1111/bcp.13018

    2. The Medication Reconciliation Process and Classification of Discrepancies: A Systematic Review

      Enas Almanasreh, Rebekah Moles and Timothy F. Chen

      Accepted manuscript online: 20 MAY 2016 06:16AM EST | DOI: 10.1111/bcp.13017

  4. Paediatric Clinical Pharmacology

    1. Evaluating renal function and age as predictors of amikacin clearance in neonates: model-based analysis and optimal dosing strategies

      Sílvia M. Illamola, Helena Colom and J. G. Coen van Hasselt

      Accepted manuscript online: 20 MAY 2016 05:41AM EST | DOI: 10.1111/bcp.13016

  5. New Drug Mechanisms

    1. Sofosbuvir and Daclatasvir

      Marleen H. M. Hessel, Adam F. Cohen and Robert Rissmann

      Accepted manuscript online: 16 MAY 2016 04:15AM EST | DOI: 10.1111/bcp.13011

  6. Drug Safety

    1. Statin-induced liver Injury in an area endemic for hepatitis B virus infection: risk factors and outcome analysis

      Li Yueh Wang, Yi-Shin Huang, Chin-Lin Perng, Bryan Huang and Han-Chieh Lin

      Accepted manuscript online: 16 MAY 2016 03:05AM EST | DOI: 10.1111/bcp.13009

  7. Reviews

    1. You have free access to this content
      Recommendations for Genetic Testing to Reduce the Incidence of Anthracycline-induced Cardiotoxicity

      Folefac Aminkeng, Colin J. D. Ross, Shahrad R. Rassekh, Soomi Hwang, Michael J. Rieder, Amit P. Bhavsar, Anne Smith, Shubhayan Sanatani, Karen A. Gelmon, Daniel Bernstein, Michael R. Hayden, Ursula Amstutz, Bruce C. Carleton and CPNDS Clinical Practice Recommendations Group

      Accepted manuscript online: 16 MAY 2016 02:20AM EST | DOI: 10.1111/bcp.13008

  8. Pharmacokinetics

    1. Population pharmacokinetics and prophylactic antiemetic efficacy of ramosetron in surgical patients

      Yong-Hun Lee, Jae-Hyeon Seo, Kyung-Tae Min, Young-Jin Lim, Seong-Wook Jeong, Eun-Kyung Lee, Byung-Moon Choi and Gyu-Jeong Noh

      Accepted manuscript online: 14 MAY 2016 01:15PM EST | DOI: 10.1111/bcp.13010

  9. Drug Safety

    1. The impact of a Medication Review with Follow-up service on hospital admissions in aged polypharmacy patients

      A. Malet-Larrea, E. Goyenechea, V. García-Cárdenas, B. Calvo, J. M. Arteche, P. Aranegui, J. J. Zubeldia, M. A. Gastelurrutia, F. Martínez-Martínez and S. I. Benrimoj

      Accepted manuscript online: 14 MAY 2016 11:55AM EST | DOI: 10.1111/bcp.13012

  10. Review - Themed Issue

    1. You have free access to this content
      Traditional Chinese Medicines in the management of cardiovascular diseases: a comprehensive systematic review

      Kerry Layne and Albert Ferro

      Accepted manuscript online: 14 MAY 2016 11:15AM EST | DOI: 10.1111/bcp.13013

  11. Translational Research

    1. Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers

      Bart A. W. Jacobs, Maarten J. Deenen, Dick Pluim, J. G. Coen van Hasselt, Martin D. Krähenbühl, Robin M. J. M. van Geel, Niels de Vries, Hilde Rosing, Didier Meulendijks, Artur M. Burylo, Annemieke Cats, Jos H. Beijnen, Alwin D. R. Huitema and Jan H. M. Schellens

      Accepted manuscript online: 10 MAY 2016 05:51AM EST | DOI: 10.1111/bcp.13007

  12. Drug Safety

    1. Respiratory effect of beta-blocker eye drops in asthma: population based study and meta-analysis of clinical trials

      Daniel R. Morales, Tobias Dreischulte, Brian J. Lipworth, Peter T. Donnan, Cathy Jackson and Bruce Guthrie

      Accepted manuscript online: 10 MAY 2016 03:50AM EST | DOI: 10.1111/bcp.13006

  13. Systematic Reviews

    1. You have free access to this content
      Direct oral anticoagulants for stroke prevention in patients with atrial fibrillation: meta-analysis by geographic region with a focus on european patients

      Antonio A. Gómez-Outes, Ana-Isabel Terleira-Fernández, Gonzalo Calvo-Rojas, Mª. Luisa Suárez-Gea and Emilio Vargas-Castrillón

      Accepted manuscript online: 10 MAY 2016 02:55AM EST | DOI: 10.1111/bcp.13005

  14. Review-Themed Issue

    1. Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis

      S. Marcone, O. Belton and D. J. Fitzgerald

      Accepted manuscript online: 6 MAY 2016 04:41AM EST | DOI: 10.1111/bcp.13002

  15. Pharmacokinetics

    1. Salivary Caffeine Concentrations are Comparable to Plasma Concentrations in Preterm Infants Receiving Extended Caffeine Therapy

      N. R. Dobson, X. Liu, L. M. Rhein, R. A. Darnall, M. J. Corwin, B. L. McEntire, R. M. Ward, L. P. James, C. M. T. Sherwin, T. C. Heeren and C. E. Hunt

      Accepted manuscript online: 4 MAY 2016 04:00PM EST | DOI: 10.1111/bcp.13001

  16. Pharmacoepidemiology

    1. Prescribing Trends of Attention-Deficit Hyperactivity Disorder (ADHD) Medications in UK Primary Care, 1995-2015

      Christel Renoux, Ju-Young Shin, Sophie Dell'Aniello, Emma Fergusson and Samy Suissa

      Accepted manuscript online: 4 MAY 2016 02:31PM EST | DOI: 10.1111/bcp.13000

  17. Pharmacokinetics

    1. Model-based evaluation of pulmonary pharmacokinetics in asthmatic and COPD patients after oral olodaterol inhalation

      Jens Markus Borghardt, Benjamin Weber, Alexander Staab, Christina Kunz and Charlotte Kloft

      Accepted manuscript online: 4 MAY 2016 01:30PM EST | DOI: 10.1111/bcp.12999

  18. Methods in Clinical Pharmacology

    1. Methodological quality of antimalarial randomized controlled trials during pregnancy and its impact on the risk of low birth weight

      Flory T. Muanda and Anick Bérard

      Accepted manuscript online: 4 MAY 2016 12:30PM EST | DOI: 10.1111/bcp.12998

  19. Pharmacokinetic Dynamic Relationships

    1. R-and S-citalopram concentrations have differential effects on neuropsychiatric scores in elders with dementia and agitation

      T. Ho, B. G. Pollock, B. H. Mulsant, O. Schantz, D. P. Devanand, J. E. Mintzer, A. P. Porsteinsson, L. S. Schneider, D. Weintraub, J. Yesavage, L. T. Drye, C. A. Munro, D. M. Shade, C. Lyketsos and R. Bies

      Accepted manuscript online: 4 MAY 2016 11:31AM EST | DOI: 10.1111/bcp.12997

  20. Reviews

    1. Cell membranes… and how long drugs may exert beneficial pharmacological activity in vivo.

      Georges Vauquelin

      Accepted manuscript online: 2 MAY 2016 05:30AM EST | DOI: 10.1111/bcp.12996

  21. Pharmacoepidemiologies

    1. Potentially inappropriate prescribing according to STOPP and START and adverse outcomes in community-dwelling older people: a prospective cohort study

      Frank Moriarty, Kathleen Bennett, Caitriona Cahir, Rose Anne Kenny and Tom Fahey

      Accepted manuscript online: 2 MAY 2016 05:18AM EST | DOI: 10.1111/bcp.12995

  22. Pharmacokinetic Dynamic Relationships

    1. Models for change in tumour size, appearance of new lesions and survival probability in patients with advanced epithelial ovarian cancer

      Chiara Zecchin, Ivelina Gueorguieva, Nathan H. Enas and Lena E. Friberg

      Accepted manuscript online: 2 MAY 2016 04:45AM EST | DOI: 10.1111/bcp.12994

  23. Drugs in Pregnancy and Lactation

    1. Population Pharmacokinetics of 17α-hydroxyprogesterone caproate in singleton gestation

      Shringi Sharma, Steve Caritis, Gary Hankins, Menachem Miodovnik, Mary F. Hebert, Don Mattison and Raman Venkatramanan

      Accepted manuscript online: 2 MAY 2016 12:10AM EST | DOI: 10.1111/bcp.12990

  24. Clinical Trials

    1. Pharmacokinetic-pharmacodynamic modeling of acute N-terminal pro B-type natriuretic peptide after doxorubicin infusion in breast cancer

      Shuang Liang, Richard C. Brundage, Pamala A. Jacobson, Anne Blaes and Mark N. Kirstein

      Accepted manuscript online: 29 APR 2016 11:15AM EST | DOI: 10.1111/bcp.12989

  25. Pharmacokinetics

    1. You have full text access to this OnlineOpen article
      Pharmacokinetics of ixazomib, an oral proteasome inhibitor, in solid tumour patients with moderate or severe hepatic impairment

      N. Gupta, M. J. Hanley, K. Venkatakrishnan, R. Perez, R. E. Norris, J. Nemunaitis, H. Yang, M. G. Qian, G. Falchook, R. Labotka and S. Fu

      Accepted manuscript online: 28 APR 2016 03:30AM EST | DOI: 10.1111/bcp.12991

  26. Clinical Trials

    1. You have full text access to this OnlineOpen article
      Brentuximab vedotin, an antibody-drug conjugate, in patients with CD30-positive haematologic malignancies and hepatic or renal impairment

      B. Zhao, R. Chen, O. A. O'Connor, A. K. Gopal, R. Ramchandren, A. Goy, J. V. Matous, A. A. Fasanmade, T. J. Manley and T. H. Han

      Accepted manuscript online: 26 APR 2016 11:25AM EST | DOI: 10.1111/bcp.12988

  27. Reviews

    1. Therapeutic Nucleic Acids: Current clinical status

      Nithya J. Gogtay and Kannan Sridharan

      Accepted manuscript online: 25 APR 2016 06:17AM EST | DOI: 10.1111/bcp.12987

  28. Pharmacokinetics

    1. Pharmacokinetics of lamotrigine and its metabolite N-2-glucuronide: Influence of polymorphism of UDP-glucuronosyltransferases and drug transporters

      Daniela Milosheska, Bogdan Lorber, Tomaž Vovk, Matej Kastelic, Vita Dolžan and Iztok Grabnar

      Accepted manuscript online: 20 APR 2016 10:35AM EST | DOI: 10.1111/bcp.12984

  29. Pharmacoepidemiologies

    1. Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.

      Adrian A. Root, Angel Y. S. Wong, Yonas Ghebremichael-Weldeselassie, Liam Smeeth, Krishnan Bhaskaran, Stephen J. W. Evans, Ruth Brauer, Ian Chi Kei Wong, Vidya Navaratnam and Ian Douglas

      Accepted manuscript online: 19 APR 2016 07:06AM EST | DOI: 10.1111/bcp.12983

  30. Meta-analysis

    1. Peripheral vasoconstriction induced by beta-blockers: a systematic review and a network meta-analysis.

      C. Khouri, T. Jouve, S. Blaise, P. Carpentier, J. L. Cracowski and M. Roustit

      Accepted manuscript online: 16 APR 2016 02:30PM EST | DOI: 10.1111/bcp.12980

  31. Drugs in Pregnancy and Lactation

    1. Atropinic burden of drugs during pregnancy and psychological development of children: a cohort study in the EFEMERIS database

      Anna-Belle Beau, Jean-Louis Montastruc, Isabelle Lacroix, François Montastruc, Caroline Hurault-Delarue and Christine Damase-Michel

      Accepted manuscript online: 16 APR 2016 01:50PM EST | DOI: 10.1111/bcp.12978

  32. Pharmacokinetics

    1. Population pharmacokinetic analysis to recommend the optimal dose of udenafil in patients with mild and moderate hepatic impairment

      Anhye Kim, Jongtae Lee, Donghoon Shin, Yong Jin Jung, Mi Young Bahng, Joo-Youn Cho and In-Jin Jang

      Accepted manuscript online: 16 APR 2016 01:10PM EST | DOI: 10.1111/bcp.12977

  33. Systematic Reviews

    1. The feasibility and the effect of deprescribing in older adults on mortality and health: A systematic review

      Amy T. Page, Rhonda M. Clifford, Kathleen Potter, Darren Schwartz and Christopher D. Etherton-Beer

      Accepted manuscript online: 14 APR 2016 03:45PM EST | DOI: 10.1111/bcp.12975

  34. Pharmacokinetics

    1. You have full text access to this OnlineOpen article
      COMPARE: pharmacokinetic profiles of subcutaneous peginterferon beta-1a and subcutaneous interferon beta-1a over 2 weeks in healthy subjects

      Xiao Hu, Shulian Shang, Ivan Nestorov, Jawad Hasan, Ali Seddighzadeh, Katherine Dawson, Bjørn Sperling and Brian Werneburg

      Accepted manuscript online: 8 APR 2016 11:53AM EST | DOI: 10.1111/bcp.12968

  35. Reviews

    1. Injection Site Reactions after subcutaneous oligonucleotide therapy

      L. van Meer, M. Moerland, J. Gallagher, M. B. A. van Doorn, E. P. Prens, A. F. Cohen, R. Rissmann and J. Burggraaf

      Accepted manuscript online: 7 APR 2016 11:02AM EST | DOI: 10.1111/bcp.12961

  36. Review - Themed Issue

    1. Systems biology approaches to understand the effects of nutrition and promote health

      Lina Badimon, Gemma Vilahur and Teresa Padro

      Accepted manuscript online: 7 APR 2016 09:08AM EST | DOI: 10.1111/bcp.12965

  37. Clinical Trials

    1. Pharmacodynamics, pharmacokinetics, and safety of ticagrelor in Chinese patients with stable coronary artery disease

      Haiyan Li, Jingchuan Guo, Glenn F. Carlson and Renli Teng

      Accepted manuscript online: 1 APR 2016 08:15AM EST | DOI: 10.1111/bcp.12950

  38. Pharmacoepidemiology

    1. You have full text access to this OnlineOpen article
      EUROmediCAT signal detection: an evaluation of selected congenital anomaly-medication associations

      Joanne E. Given, Maria Loane, Johannes M. Luteijn, Joan K. Morris, Lolkje T. W. de Jong van den Berg, Ester Garne, Marie-Claude Addor, Ingeborg Barisic, Hermien de Walle, Miriam Gatt, Kari Klungsoyr, Babak Khoshnood, Anna Latos-Bielenska, Vera Nelen, Amanda J. Neville, Mary O'Mahony, Anna Pierini, David Tucker, Awi Wiesel and Helen Dolk

      Accepted manuscript online: 29 MAR 2016 10:55AM EST | DOI: 10.1111/bcp.12947

  39. Review-Themed Issue

    1. Dietary anthocyanins and health: data from FLORA and ATHENA EU projects

      Chiara Cerletti, Amalia de Curtis, Francesca Bracone, Cinzia Digesù, Alessio G. Morganti, Licia Iacoviello, Giovanni de Gaetano and Maria Benedetta Donati

      Accepted manuscript online: 25 MAR 2016 10:15PM EST | DOI: 10.1111/bcp.12943

  40. Clinical Trials

    1. Impact of patient characteristics on the pharmacokinetics of corifollitropin alfa during controlled ovarian stimulation

      Anthe S. Zandvliet, Marita Prohn, Rik de Greef, Frank van Aarle, Christine Mc Crary Sisk and Barbara J. Stegmann

      Accepted manuscript online: 18 MAR 2016 07:21AM EST | DOI: 10.1111/bcp.12939

  41. Meta Analysis (REV)

    1. Is the Era of intravenous proton pump inhibitors coming to an end in patients with bleeding peptic ulcers? meta-analysis of the published literature

      Zhixiang Jian, Hui Li, Nicholas S. Race, Tingting Ma, Haosheng Jin and Zi Yin

      Accepted manuscript online: 18 DEC 2015 03:49AM EST | DOI: 10.1111/bcp.12866


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