British Journal of Clinical Pharmacology

Cover image for Vol. 83 Issue 2

Edited By: A.F. Cohen (Editor-in-Chief), A. de Boer (European Editor), A. Ferro (Reviews Editor), A. Gilchrist (Online Editor), G. Isbister (Australasian Editor), S. Ross (Education Editor) and A. Webb (European Editor)

Impact Factor: 3.83

ISI Journal Citation Reports © Ranking: 2015: 49/255 (Pharmacology & Pharmacy)

Online ISSN: 1365-2125

Associated Title(s): British Journal of Pharmacology, Pharmacology Research & Perspectives



Adverse effects of herbal or dietary supplements in G6PD deficiency: a systematic review
Shaun Wen Huey Lee, Nai Ming Lai, Nathorn Chaiyakunapruk and David Weng Kwai Chong

Systematic review and meta-analysis of clinical outcomes of early caffeine therapy in preterm neonates
Kok Pim Kua and Shaun Wen Huey Lee

Optimizing identification and management of COPD patients – reviewing the role of the community pharmacist
Thys van der Molen, Job F. M. van Boven, Terence Maguire, Pankaj Goyal and Pablo Altman


Systematic review of published Phase 3 data on anti-PCSK9 monoclonal antibodies in patients with hypercholesterolaemia
Ioanna Gouni-Berthold, Olivier S. Descamps, Uwe Fraass, Elizabeth Hartfield, Kim Allcott, Ricardo Dent and Winfried März

Clinical trials for authorized biosimilars in the European Union: a systematic review
Johanna Mielke, Bernd Jilma, Franz Koenig and Byron Jones

A systematic review of tranexamic acid in hip fracture surgery
Luke S. Farrow, Toby O. Smith, George P. Ashcroft and Phyo K. Myint

UK medicines regulation: responding to current challenges
Natalie Richards and Ian Hudson

CYP2C19 and CYP2D6 genotypes in Pacific peoples
Nuala A. Helsby

Design and conduct of early phase drug studies in children: challenges and opportunities
Michael Rieder and Daniel Hawcutt

A literature review on the pharmacological sensitivity of human evoked hyperalgesia pain models
Guido van Amerongen, Matthijs W. de Boer, Geert Jan Groeneveld and Justin L. Hay

Determinants of hepatotoxicity after repeated supratherapeutic paracetamol ingestion: systematic review of reported cases
Paul Acheampong and Simon H. L. Thomas

Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy
Linda Gabrielsson, Sofia Mattsson and Christopher J. Fowler

AKT in cancer: new molecular insights and advances in drug development
Prabhjot S. Mundi, Jasgit Sachdev, Carolyn McCourt and Kevin Kalinsky

Cardiovascular effects of cyclooxygenase-2 inhibitors: a mechanistic and clinical perspective
Carlo Patrono

The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis
Amy T. Page, Rhonda M. Clifford, Kathleen Potter, Darren Schwartz and Christopher D. Etherton-Beer

Use of antipsychotics and risk of myocardial infarction: a systematic review and meta-analysis
Zheng-he Yu, Hai-yin Jiang, Li Shao, Yuan-yue Zhou, Hai-yan Shi and Bing Ruan

Direct oral anticoagulants for stroke prevention in patients with atrial fibrillation: meta-analysis by geographic region with a focus on European patients
Antonio Gómez-Outes, Ana-Isabel Terleira-Fernández, Gonzalo Calvo-Rojas, M. Luisa Suárez-Gea and Emilio Vargas-Castrillón

The medication reconciliation process and classification of discrepancies: a systematic review
Enas Almanasreh, Rebekah Moles and Timothy F. Chen

Therapeutic nucleic acids: current clinical status
Kannan Sridharan and Nithya Jaideep Gogtay

Cell membranes… and how long drugs may exert beneficial pharmacological activity in vivo
Georges Vauquelin

Recommendations for genetic testing to reduce the incidence of anthracycline-induced cardiotoxicity
Folefac Aminkeng, Colin J. D. Ross, Shahrad R. Rassekh, Soomi Hwang, Michael J. Rieder, Amit P. Bhavsar, Anne Smith, Shubhayan Sanatani, Karen A. Gelmon, Daniel Bernstein, Michael R. Hayden, Ursula Amstutz, Bruce C. Carleton and CPNDS Clinical Practice Recommendations Group

Hypoglycaemia when Adding Sulphonylurea to Metformin: A Systematic Review and Network Meta-analysis
S. E. Andersen and M. Christensenfeasabilit

Injection site reactions after subcutaneous oligonucleotide therapy
Leonie van Meer, Matthijs Moerland, Jolie Gallagher, Martijn B. A. van Doorn, Errol P. Prens, Adam F. Cohen, Robert Rissmann and Jacobus Burggraaf

The great ESCAPE – a clinical pharmacologist's journey in stroke research
David J. P. Williams

Drug-induced Raynaud's phenomenon: beyond β-adrenoceptor blockers
Charles Khouri, Sophie Blaise, Patrick Carpentier, Céline Villier, Jean-Luc Cracowski and Matthieu Roustit

Adverse drug event reporting systems: a systematic review
Chantelle Bailey, David Peddie, Maeve E. Wickham, Katherin Badke, Serena S. Small, Mary M. Doyle-Waters, Ellen Balka and Corinne M. Hohl

Japanese regulation of biosimilar products: past experience and current challenges
Teruyo Arato

N-acetylcysteine for non-paracetamol drug-induced liver injury: a systematic review
Mohamed Farouk Chughlay, Nicole Kramer, C. Wendy Spearman, Mahmoud Werfalli and Karen Cohen

Mechanism of isoniazid-induced hepatotoxicity: then and now
Imir Metushi, Jack Uetrecht and Elizabeth Phillips

Statin therapy and plasma free fatty acids: a systematic review and meta-analysis of controlled clinical trials
Amirhossein Sahebkar, Luis E. Simental-Mendía, Claudio Pedone, Gianna Ferretti, Petr Nachtigal, Simona Bo, Giuseppe Derosa, Pamela Maffioli and Gerald F. Watts

Improvement of plasma adiponectin, leptin and C-reactive protein concentrations by orlistat: a systematic review and meta-analysis
Giuseppe Derosa, Pamela Maffioli and Amirhossein Sahebkar

Review of commonly used age-based weight estimates for paediatric drug dosing in relation to the pharmacokinetic properties of resuscitation drugs
Clare Francesca Carasco, Penny Fletcher and Ian Maconochie

The risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy: a systematic review and meta-analysis
Anick Bérard, Noha Iessa, Sonia Chaabane, Flory T. Muanda, Takoua Boukhris and Jin-Ping Zhao

Can Paracetamol (Acetaminophen) Be Administered To Patients With Liver Impairment?
Kelly L. Hayward, Elizabeth E. Powell, Katharine M. Irvine and Jennifer H. Martin

Achieving The World Health Organization's Vision For Clinical Pharmacology
Jennifer H. Martin, David Henry, Jean Gray, Richard Day, Felix Bochner, Albert Ferro, Munir Pirmohamed, Klaus Mörike and Matthias Schwab

Repurposing Some Older Drugs That Cross The Blood-Brain Barrier And Have Potential Anticancer Activity To Provide New Treatment Options For Glioblastoma
Dayle Rundle-Thiele, Richard Head, Leah Cosgrove and Jennifer H. Martin

Cato Guldberg And Peter Waage, The History Of The Law Of Mass Action, And Its Relevance To Clinical Pharmacology
Robin E. Ferner and Jeffrey K. Aronson

Glucagon-Like Peptide-1(GLP-1) Receptor Agonists: Potential To Reduce Fracture Risk In Diabetic Patients?
Guojing Luo, Hong Liu and Hongyun Lu

Efficacy And Safety Of Silodosin In The Medical Expulsion Therapy For Distal Ureteral Calculi: A Systematic Review And Meta-Analysis
Wei Huang, Peng Xue, Huantao Zong, and Yong Zhang

The Law Of Mass Action And The Pharmacological Concentration-Effect Curve:Resolving The Paradox Of Apparently Non-Dose-Related Adverse Drug Reactions
Jeffrey K. Aronson and Robin E. Ferner

Does Celecoxib Improve The Efficacy Of Chemotherapy For Advanced Non-Smallcell Lung Cancer?
Leng-Chen Hou, Fang Huang and Hong-Bin Xu

Incidence And Risk Of Severe Infections Associated With Aflibercept In Cancer Patients: A Systematic Review And Meta-Analysis
Xi Zhang, Yuge Ran, Yongjie Shao, Kunjie Wang and Yuanxue Zhu

Treating Disorders Of The Neonatal Central Nervous System: Pharmacokineticand Pharmacodynamic Considerations With A Focus On Antiepileptics
Maria D. Donovan, Geraldine B. Boylan, Deirdre M. Murray, John F. Cryan and Brendan T. Griffin

The Mass Action Equation In Pharmacology
Terry Kenakin