Clinical & Experimental Immunology

Cover image for Vol. 179 Issue 2

Edited By: M. Peakman

Impact Factor: 3.278

ISI Journal Citation Reports © Ranking: 2013: 60/144 (Immunology)

Online ISSN: 1365-2249

Virtual Issues

Clinical & Experimental Immunology FREE Virtual Issue

Dying autologous cells as instructors of the immune system

Series Originators and Editors: Christian Berens and Martin Herrmann
December 2014

This virtual issue is based on a series of articles commissioned and collected together for Clinical & Experimental Immunology. The way in which the immune system reacts to dead and dying cells is key in the pathogenesis of a number of diseases, with impaired clearance of apoptotic cells being implicated in many conditions such as diabetes, Alzheimer’s disease, atherosclerosis and cancer. The articles in this series give some insight into how cell death and the immune system interact; we hope they will spark interest and debate and encourage research efforts into further elucidating the role of cell death in the immune system. These articles are being published together as a series and will appear in the January 2015 issue of Clinical & Experimental Immunology, Volume 179, Number 1.
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Dying autologous cells as instructors of the immune system
L.E. Munoz, M. Hermann and C. Berens

Review articles

Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: critical remarks
O. P. Rekvig

The effect of cell death in the initiation of lupus nephritis
K. Fenton

Original articles

Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages
A. Tomin, T. Dumych, Y. Tolstyak, I. Kril, I. Mahorivska, E. Bila, R. Stoika, M. Herrmann, Y. Kit and R. Bilyy

Instructive influences of phagocytic clearance of dying cells on neutrophil extracellular trap generation
A. A. Manfredi, C. Covino, P. Rovere-Querini and N. Maugeri

Developmental regulation of p53-dependent radiation-induced thymocyte apoptosis in mice
A. Gentil Dit Maurin, C. Lemercier, V. Collin-Faure, P. N. Marche, E. Jouvin-Marche and S. M. Candéias

Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity
M. Zirngibl, B. G. Fürnrohr, C. Janko, L. E. Munoz, R. E. Voll, C. D. Gregory. G. Schett and M. Herrmann

Low and moderate dose of ionising radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine milieu, but do not impact upon viability and phagocytic function
R. Wunderlich, A. Ernst, F. Rödel, R. Fietkau, O. Ott, K. Lauber, B. Frey, U. S. Gaipl

Vessel-associated myogenic precursors control macrophage activation and clearance of apoptotic cells
L. Bosurgi, S. Brunelli, E. Rigamonti, A. Monno, A. A. Manfredi and P. Rovere-Querini

Acetylated histones contribute to the immunostimulatory potential of neutrophil extracellular traps in systemic lupus erythematosus
E. Pieterse, J. Hofstra, J. Berden, M. Herrmann, J. Dieker and J. van der Vlag

Unconventional apoptosis of polymorphonuclear neutrophils (PMN): staurosporine delays exposure of phosphatidylserine and prevents phagocytosis by MΦ-2 macrophages of PMN
S. Franz, L. E. Muñoz, P. Heyder, M. Herrmann and M. Schiller