Genes to Cells

Cover image for Vol. 23 Issue 1

Edited By: Mitsuhiro Yanagida

Impact Factor: 1.993

ISI Journal Citation Reports © Ranking: 2016: 107/167 (Genetics & Heredity); 147/190 (Cell Biology)

Online ISSN: 1365-2443

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Recently Published Articles

  1. Tumor necrosis factor-α regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells

    Yasunobu Iwai, Keisuke Noda, Mizuho Yamazaki, Ayako Kato, Masaru Mezawa, Hideki Takai, Yohei Nakayama and Yorimasa Ogata

    Version of Record online: 22 JAN 2018 | DOI: 10.1111/gtc.12561

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    Follicular dendritic cell-secreted protein (FDC-SP) is a secreted protein expressed in follicular dendritic cells, periodontal ligament and junctional epithelium.

  2. Preferable in vitro condition for maintaining faithful DNA methylation imprinting in mouse embryonic stem cells

    Jiyoung Lee, Ayumi Matsuzawa, Hirosuke Shiura, Akito Sutani and Fumitoshi Ishino

    Version of Record online: 22 JAN 2018 | DOI: 10.1111/gtc.12560

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    The imprinted memory in ESCs and even in ICM cells derived from a BJ hybrid is labile and able to change under variable culture conditions and is mostly sensitive to the presence of 2i or KSR. DNA methylation imprinting can be more faithfully maintained under condition of cooperative FBS and 2i.

  3. Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass

    Bo Yang, Takahiro Kumoto, Takeshi Arima, Minako Nakamura, Yohei Sanada, Thanutchaporn Kumrungsee, Yusuke Sotomaru, Masayuki Shimada and Noriyuki Yanaka

    Version of Record online: 17 JAN 2018 | DOI: 10.1111/gtc.12558

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    Areg mRNA expression was significantly up-regulated in mouse obese adipose tissues, and over-expression of Areg in white adipose tissue caused less adipose tissue mass.

  4. MicroRNA-664a-5p promotes neuronal differentiation of SH-SY5Y cells

    Kazunori Watanabe, Ryuhei Yamaji and Takashi Ohtsuki

    Version of Record online: 17 JAN 2018 | DOI: 10.1111/gtc.12559

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    miR-664a-5p promoted neuronal differentiation.

  5. Identification of miR-305, a microRNA that promotes aging, and its target mRNAs in Drosophila

    Makiko Ueda, Tetsuya Sato, Yasuyuki Ohkawa and Yoshihiro H. Inoue

    Version of Record online: 5 JAN 2018 | DOI: 10.1111/gtc.12555

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    We showed that miR-305 overexpression leads to a short lifespan and enhances the age-dependent loss of locomotor activity, the accumulation of poly-ubiquitinated protein aggregates in the flight muscles and the sensitivity to oxidative stress, whereas reduced miR-305 expression leads to an extended lifespan and suppresses the age-dependent loss of locomotor activity, the accumulation of poly-ubiquitinated protein aggregates and the sensitivity to oxidative stress in Drosophila. These findings indicate that miR-305 influences the progression of aging in Drosophila. Moreover, we identified candidate target mRNAs for miR-305, such as the mRNA of several antimicrobial peptides.

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