Genes to Cells

Cover image for Vol. 22 Issue 9

Edited By: Mitsuhiro Yanagida

Impact Factor: 1.993

ISI Journal Citation Reports © Ranking: 2016: 106/166 (Genetics & Heredity); 145/189 (Cell Biology)

Online ISSN: 1365-2443

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Recently Published Articles

  1. Elucidation of GlcNAc-binding properties of type III intermediate filament proteins, using GlcNAc-bearing polymers

    Hirohiko Ise, Sadanori Yamasaki, Kazuaki Sueyoshi and Yoshiko Miura

    Version of Record online: 12 SEP 2017 | DOI: 10.1111/gtc.12535

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    Confocal laser scanning images show the interactions of cell surface-expressed vimentin with GlcNAc-bearing polymers and the localization of caveolin-1 on HeLa cells.

  2. Effect of different light–dark schedules on estrous cycle in mice, and implications for mitigating the adverse impact of night work

    Kiichi Yoshinaka, Ai Yamaguchi, Ritsuko Matsumura, Koichi Node, Isao Tokuda and Makoto Akashi

    Version of Record online: 8 SEP 2017 | DOI: 10.1111/gtc.12522

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    Here, we report that repetitive reversal of light-dark (LD) cycles triggers irregular estrous cycles in mice. The findings revealed that the estrous cycle remained irregular for more than four weeks after the mice were returned to regular LD cycles. Importantly, the magnitude of the negative impact of reversed LD cycles on the estrous cycle was dependent on the difference in the frequency of LD reversal.

  3. Extracellular vesicle-mediated MFG-E8 localization in the extracellular matrix is required for its integrin-dependent function in mouse mammary epithelial cells

    Takuya Ooishi, Daita Nadano, Tsukasa Matsuda and Kenzi Oshima

    Version of Record online: 8 SEP 2017 | DOI: 10.1111/gtc.12521

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    Mouse MFG-E8 was transiently localized to the mammary basal lamina during involution. MFG-E8 was connected extracellular matrix with extracellular vesicles, and this basal localization was required for its integrin-dependent function in adherent cells.

  4. Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p

    Masako Koyama, Hidemi Hirano, Natsuki Shirai and Yoshiyuki Matsuura

    Version of Record online: 8 AUG 2017 | DOI: 10.1111/gtc.12520

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    This article describes structural and biochemical characterization of the interactions between the Xpo1p nuclear export complex and the FG repeats of Nup42p, a nucleoporin localized at the cytoplasmic face of nuclear pore complexes in yeast. The results of this study extend our understanding of the role of Nup42p in the terminal stage of nuclear export. The structure presented here also provides insights into evolutionary conservation of the FG repeat binding sites on CRM1 (Xpo1p) across species.

  5. Many transcription factors contribute to C. elegans growth and fat storage (pages 770–784)

    Akihiro Mori, Amy D. Holdorf and Albertha J.M. Walhout

    Version of Record online: 8 AUG 2017 | DOI: 10.1111/gtc.12516

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    The genes that contribute only subtly are often missed. Here, we address this challenge by focusing on two phenotypes in C. elegans: growth and fat storage. Our results show the distribution of relative body size versus corrected relative fat score of 854 C. elegans TF RNAi knockdowns.