Cover image for Vol. 23 Issue 3

Co-Editors C. Kessler and M. Makris

Impact Factor: 2.673

ISI Journal Citation Reports © Ranking: 2015: 35/70 (Hematology)

Online ISSN: 1365-2516

Author Guidelines

Submission of Manuscripts
Acceptance decisions are made rapidly; authors should receive reviewers' comments within four weeks of receipt of the manuscript. Papers which do not conform to the general criteria for publication in Haemophilia will be returned immediately to the authors without detailed review, to avoid unnecessary delay in submission elsewhere. When papers are accepted subject to revision, only a single revised version will be considered; it should be submitted within three months of the initial acceptance. The journal aims to publish articles within four months of acceptance in revised form.

Manuscripts should be submitted online at http://mc.manuscriptcentral.com/hae. Full instructions and support are available on the site. Submitting authors will need a user ID and password, which can be obtained on first use of the site. All files must be available in an electronic format, preferably generic rich text format (RTF) or Microsoft Word for text and GIF, JPEG, TIFF, EPS, PNG, Microsoft PowerPoint or Excel for figures. It is recommended that, where possible, figures be embedded into a single Microsoft Word document. Support can be contacted by phone (+1 434-817-2040 ext 167), e-mail (ts.mcsupport@thomson.com) or go to http://blackwellsupport.custhelp.com. If you cannot submit online please contact the European Editorial Office. All papers will be refereed by at least two independent referees.

A covering letter must be included, signed by the corresponding author and stating on behalf of all the authors that the work has not been published and is not being considered for publication elsewhere. Articles are accepted for publication at the discretion of the Editor(s).

All manuscripts must be accompanied by the Declaration of Interests form signed and completed by ALL authors.

Christine Lee Haemophilia Journal Award
Established in 2012 by the World Federation of Hemophilia and Wiley-Blackwell, the Christine Lee Haemophilia Journal Award is given to a young researcher in recognition of the best article published in Haemophilia, the official journal of the WFH, in a calendar year. This Award will be given annually starting in 2013. The selection committee, including the Journal’s Editors and WFH representatives on the Editorial Board, will choose the best paper published in Haemophilia between January 1 and December 31of each year, within the first quarter of the subsequent year.
A prize of $3,000 and a three-year online personal subscription to Haemophilia is provided for this award.
The young researcher must be under the age of 40 at the time the article is submitted. If there are multiple authors, the lead author must be under the age of 40 at the time the article is submitted.

NEW: Pre-submission English-language editing
Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at http://authorservices.wiley.com/bauthor/english_language.asp. All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Online Open
OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley InterScience, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see http://olabout.wiley.com/WileyCDA/Section/id-406241.html.

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at: https://authorservices.wiley.com/bauthor/onlineopen_order.asp. Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

Copyright procedures
If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper. The corresponding author MUST submit the CTA as it is a requirement for publication.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:
CTA Terms and Conditions http://authorservices.wiley.com/bauthor/faqs_copyright.asp.

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

• Creative Commons Attribution License OAA
• Creative Commons Attribution Non-Commercial License OAA
• Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://authorservices.wiley.com/bauthor/faqs_copyright.asp and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements.

For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.

Additionally. authors are themselves responsible for obtaining permission to reproduce copyright material from other sources.

Declaration of Interest
ALL authors must sign the Declaration of Interests form. These forms must be submitted together with your manuscript. Missing forms will result in a delay in publication for your article. In your manuscript, all necessary declarations of interests must be included.

For papers where there are no competing interest for all authors, the statement "The authors stated that they had no interests which might be perceived as posing a conflict or bias" will be added in the disclosures section.

Authors are required to disclose financial interests in any company or institution that might benefit from their publication. A competing interest exists when a primary interest (such as patients’ welfare or the validity of research) might be influenced by a secondary interest (such as financial gain or personal rivalry). It may arise for the authors of a Haemophilia article when they have a financial interest that may influence their interpretation of their results or those of others. Financial interests are the easiest to define and they have the greatest potential to influence the objectivity, integrity or perceived value of a publication. They may include any or all, but are not limited to, the following:

• Personal financial interests: Stocks or shares in companies that may gain or lose financially through publication; consultant fees or fees from speakers bureaus other forms of remuneration from organisations that may gain or lose financially; patents or patent applications whose value may be affected by publication.
• Funding: Research support from organisations that might gain or lose financially through publication of the paper.
• Employment: Recent, present or anticipated employment of you or a family member by any organization that may gain or lose financially through publication of the paper. Any such interest that authors may have should be declared. The aim of the statement is not to eradicate competing interests, as they are almost inevitable. Papers will not be rejected because there is a competing interest, but a declaration on whether or not there are competing interests will be added to the paper.
• Patent rights
• Consultancy work.

All sources of funding must be stated in the disclosures section. List governmental, industrial, charitable, philanthropic and/or personal sources of funding used for the studies described in the manuscript. Attribution of these funding sources is preferred. Examples:

• This work was supported by a grant from the National Institutes of Health, USA (DKxxxx to AB).
• This work was supported by the Crohn's and Colitis Foundation of Canada (grant to AB and CD).
• This work was supported by a grant from Big Pharma Inc. (to AB) and equipment was donated by Small Pharma Inc. EF received a graduate studentship award from the University of xxxxx.

We will also ask reviewers to provide a declaration of interest.

Note to NIH Grantees
Pursuant to NIH mandate, Wiley-Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance.  This accepted version will be made publicly available 12 months after publication.  For further information, see www.wiley.com/go/nihmandate.

Publication Ethics
Please read the Ethical Policies of Haemophilia prior to submitting to the Journal.

A full list of collaborators may be included as an Appendix
All authors must fulfil the following three criteria:

• Substantial contributions to research design, or the acquisition, analysis or interpretation of data,
• Drafting the paper or revising it critically, and
• Approval of the submitted and final versions.

In the Acknowledgments section of the paper all authors, must indicate their specific contributions to the work described in the manuscript. Some examples include:

• X performed the research
• Y designed the research study
• Z contributed essential reagents or tools
• A analysed the data
• B wrote the paper.
An author may list more than one contribution, and more than one author may have contributed to the same element of the work. E.g. ‘A performed the research, A and C analysed the data and wrote the paper, E contributed the knockout mice for the study and G designed the research study and wrote the paper’.

Role of professional medical writers in peer-reviewed publications
Please ensure that you follow the guidelines by the European Medical Writers Association on the role of medical writers. The guidelines emphasise the importance of respecting widely recognised authorship criteria, and in particular of ensuring that all people listed as named authors have full control of the content of papers. The role of professional medical writers must be transparent. Please name any professional medical writer among the list of contributors to any article for Haemophilia(not only original research papers), and specify in the acknowledgements and statement of competing interests for the article who paid the writer. Writers and authors must have access to relevant data while writing papers.

NEW: CrossCheck Plagiarism Software
Haemophilia employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

Presentation of Manuscripts
The manuscript should be double-spaced with 30mm margins. Manuscripts must be numbered consecutively in the following sequence:  Title Page;  Abstract,  if required;  Main Body of Text;  Acknowledgement;  Reference List;  Tables and Figure caption List.

1. Title page
The title page should contain the following information:
1. full title of the paper
2. the full names of all the authors
3. the name(s) and address(es) at which the work was carried out (the present addresses of the authors, if different from the above, should appear in a footnote)
4. the name, address, telephone and fax numbers and e-mail address of the author to whom all correspondence and proofs should be sent
5. a running title of not more than 50 characters, including spaces; and six keywords for indexing.

2. Abstract
A structured abstract of no more than 250 words is required for original articles, subdivided into the following sequential sections: Introduction; Aim; Methods; Results; Conclusion. Review articles do not require a structured abstract.

3. Main body of text
The text of original and review articles should be subdivided under the headings: Introduction; Materials and Methods; Results; Discussion and Conclusion. The Results and Discussion sections may be combined and may contain subheadings. The Materials and Methods section should be sufficiently detailed to enable the experiments to be reproduced. Trade names should be capitalized and the manufacturer's name and address given.

4. Acknowledgments
The declaration of interest statement must be included in the Acknowledgement section of your manuscript. For papers where there are no competing interests (for all authors) the statement "the authors stated that they had no interests which might be perceived as posing a conflict or bias" will be added here.

5. References

References in Articles
References must be numbered consecutively in the order in which they appear in the text and be identified by square brackets, e.g. [1, 5, 7-9]. Titles of journals should be abbreviated in line with Index Medicus. List all authors when seven or fewer; when more than seven give six, followed by et al. For style of References in the list, see a recent issue of Haemophilia.

Units and Spelling
Systéme International (SI) units should be used, as given in Units, Symbols and Abbreviations (4th edn, 1988), published by the Royal Society of Medicine Services Ltd, London. If special circumstances necessitate the use of other units these should be defined on first appearance in terms of SI units, e.g. mmHg. Spelling should conform to The Concise Oxford Dictionary (Oxford University Press).

6. Tables and figures
The preferred position of figures and tables in the text should be indicated in the left-hand margin.

Illustrations should be referred to in the text as figures using Arabic numbers, e.g. Fig. 1 etc., in order of appearance. Three copies of each figure must be submitted and each should be marked on the back with its number, together with the name(s) of the author(s) and the title of the paper. The top should be marked with an arrow. Photographs and photomicrographs should be unmounted glossy prints and should not be retouched. For electronic submission, illustrations should be embedded in the main document or uploaded in the recommended formats. Quality should be sufficient for on-screen viewing and desk-top printing. High quality versions will be accepted on acceptance.

Colour illustrations are acceptable when found necessary by the Editor(s), but the author may be asked to contribute towards the cost. Line drawings should be on separate sheets of white paper in black indelible ink or photographic prints thereof (dot matrix illustrations are not permitted). Each figure must have a separate legend; these should be grouped on a separate page at the end of the manuscript. All symbols and abbreviations must be clearly explained. Figures that have been created electronically should be saved using the 'normal' save process of the software program and also as a postscript or EPS file.

Tables should include only essential data. Each table should be typewritten on a separate sheet and must be numbered consecutively with Arabic numerals, e.g. Table 1, and given a short caption. Vertical rules should not be used. Units should appear in parentheses in the column headings and not in the body of the table. All abbreviations should be defined in a footnote.

All tables and figures that are reproduced from a previously published source must be accompanied by a letter of permission from the publisher or copyright owner.

Types of articles

Original Articles
Original articles should not exceed 3,000 words with a maximum of 40 references. Longer Articles will be considered for online only publication at the discretion of the Editor. A word count should be included in the cover letter.

Review Articles
Review articles should not exceed 4,000 words with a maximum of 60 references. Longer Reviews will be considered for online only publication at the discretion of the Editor. A word count should be included in the cover letter.

Letters to the Editor
These do not require abstracts, are written without subtitles, should be no more than 1,500 words and contain no more than 10 references and up to 2 tables or figures. A right of reply will be extended to the original authors at the discretion of the Editors. All letters submitted to the journal will be published online-only.

Editorials and Commentaries
These are commissioned by the editors. They have no abstract and should be no more than 1,500 words and contain no more than 20 references.

Please note: the Editors reserve the right to change the article type of submitted manuscripts.

It is the policy of Haemophilia for authors to pay the full cost for the reproduction of their colour artwork.

Therefore, please note that if there is colour artwork in your manuscript when it is accepted for publication, Wiley-Blackwell require you to complete and return a Colour Work Agreement form before your paper can be published.

If you are unable to access the internet, or are unable to download the form, please contact the Production Editor (contact details given above) and they will be able to send a form to you.

Please post or courier all pages of your completed form to :
Customer Service (OPI)
John Wiley & Sons Ltd, European Distribution Centre
New Era Estate
Oldlands Way
Bognor Regis West Sussex
PO22 9NQ

Electronically sent forms will not be accepted.

Any article received by Wiley-Blackwell with colour work will not be published until the form has been returned.

*To read PDF files, you must have Acrobat Reader installed on your computer. If you do not have this program, this is available as a free download from the following web address: http://www.adobe.com/products/acrobat/readstep2.html

Early View
Haemophilia is covered by Wiley-Blackwell's Early View service, which means that, once we have received your corrections, your article will be published online without having to wait for inclusion in a print issue. Please note that the version of your paper that appears online is complete and final, except for volume, issue and page numbers, which are added upon print publication. Therefore, there will be no further opportunity to make changes to your article after online publication.

Authors' original materials
Unless specifically requested by a society or individual author, hardcopy and electronic materials will be retained for no longer than two months following publication of each issue. Any hardcopy and electronic material should then be disposed of or recycled. This includes original artwork, hardcopy text and any accompanying disks/CD-Roms. Any author wishing for any of their materials to be returned should alert the Production Editor via the Editorial Office at the submission stage, or at the latest to the Production Editor directly on receipt of proofs. No responsibility will be taken for author material being destroyed if there has been no indication given that it should be returned.

Page Proofs and Offprints
Page proofs must be returned to the Publisher within three days of receipt, by fax if convenient; only typographical errors can be corrected at this stage. Page proofs will be supplied as portable document format (PDF) files sent by e-mail, where possible.

Guidelines for Cover Submissions

If you would like to send suggestions for artwork related to your manuscript to be considered to appear on the cover of the journal, please follow these general guidelines.