International Endodontic Journal

Cover image for Vol. 48 Issue 1

Edited By: PMH Dummer

Impact Factor: 2.273

ISI Journal Citation Reports © Ranking: 2013: 16/82 (Dentistry Oral Surgery & Medicine)

Online ISSN: 1365-2591



Author Guidelines


Content of Author Guidelines: 1. General, 2. Ethical Guidelines, 3. Manuscript Submission Procedure, 4. Manuscript Types Accepted, 5. Manuscript Format and Structure, 6. After Acceptance
 
Useful Websites: Submission Site, Articles published in International Endodontic Journal, Author Services, Wiley Blackwell’s Ethical Guidelines, Guidelines for Figures

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

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1. GENERAL
International Endodontic Journal publishes original scientific articles, reviews, clinical articles and case reports in the field of Endodontology; the branch of dental sciences dealing with health, injuries to and diseases of the pulp and periradicular region, and their relationship with systemic well-being and health. Original scientific articles are published in the areas of biomedical science, applied materials science, bioengineering, epidemiology and social science relevant to endodontic disease and its management, and to the restoration of root-treated teeth. In addition, review articles, reports of clinical cases, book reviews, summaries and abstracts of scientific meetings and news items are accepted.

Please read the instructions below carefully for details on the submission of manuscripts, the journal's requirements and standards as well as information concerning the procedure after a manuscript has been accepted for publication in International Endodontic Journal. Authors are encouraged to visit Wiley Blackwell Author Services for further information on the preparation and submission of articles and figures.

2. ETHICAL GUIDELINES

International Endodontic Journal adheres to the below ethical guidelines for publication and research. 

2.1. Authorship and Acknowledgements
Authors submitting a paper do so on the understanding that the manuscript has been read and approved by all authors and that all authors agree to the submission of the manuscript to the Journal.

International Endodontic Journal adheres to the definition of authorship set up by The International Committee of Medical Journal Editors (ICMJE). According to the ICMJE, authorship criteria should be based on 1) substantial contributions to conception and design of, or acquisiation of data or analysis and interpretation of data, 2) drafting the article or revising it critically for important intellectual content and 3) final approval of the version to be published. Authors should meet conditions 1, 2 and 3.


Acknowledgements: Under acknowledgements please specify contributors to the article other than the authors accredited. Please also include specifications of the source of funding for the study and any potential conflict of interests if appropriate.

2.2. Ethical Approvals
Experimentation involving human subjects will only be published if such research has been conducted in full accordance with ethical principles, including the World Medical Association Declaration of Helsinki (version 2008) and the additional requirements, if any, of the country where the research has been carried out. Manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding and written consent of each subject and according to the above mentioned principles. A statement regarding the fact that the study has been independently reviewed and approved by an ethical board should also be included. Editors reserve the right to reject papers if there are doubts as to whether appropriate procedures have been used.

When experimental animals are used the methods section must clearly indicate that adequate measures were taken to minimize pain or discomfort. Experiments should be carried out in accordance with the Guidelines laid down by the National Institute of Health (NIH) in the USA regarding the care and use of animals for experimental procedures or with the European Communities Council Directive of 24 November 1986 (86/609/EEC) and in accordance with local laws and regulations.

All studies using human or animal subjects should include an explicit statement in the Material and Methods section identifying the review and ethics committee approval for each study. The authors MUST upload a copy of the ethical approval letter when submitting their manuscript. Editors reserve the right to reject papers if there is doubt as to whether appropriate procedures have been used.

2.3 Clinical Trials
Clinical trials should be reported using the guidelines available at www.consort-statement.org. A CONSORT checklist and flow diagram (as a Figure) should also be included in the submission material.

The International Endodontic Journal encourages authors submitting manuscripts reporting from a clinical trial to register the trials in any of the following free, public clinical trials registries: www.clinicaltrials.gov, http://clinicaltrials.ifpma.org/clinicaltrials/, http://isrctn.org/. The clinical trial registration number and name of the trial register will then be published with the paper.

2.4 Systematic Reviews
Systematic reviews should be reported using the PRISMA guidelines available at http://prisma-statement.org/. A PRISMA checklist and flow diagram (as a Figure) should also be included in the submission material.

2.5 DNA Sequences and Crystallographic Structure Determinations
Papers reporting protein or DNA sequences and crystallographic structure determinations will not be accepted without a Genbank or Brookhaven accession number, respectively. Other supporting data sets must be made available on the publication date from the authors directly.

2.6 Conflict of Interest and Source of Funding
International Endodontic Journal requires that all sources of institutional, private and corporate financial support for the work within the manuscript must be fully acknowledged, and any potential conflicts of interest noted. Grant or contribution numbers may be acknowledged, and principal grant holders should be listed. Please include the information under Acknowledgements.

2.7 Appeal of Decision
The decision on a paper is final and cannot be appealed.

2.8 Permissions
If all or parts of previously published illustrations are used, permission must be obtained from the copyright holder concerned. It is the author's responsibility to obtain these in writing and provide copies to the Publishers.

2.8 Copyright Assignment

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper. Your article cannot be published until this has been done.

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):
Creative Commons Attribution License OAA
Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://authorservices.wiley.com/bauthor/faqs_copyright.asp and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust or members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.

3. OnlineOpen
OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see
http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at:
https://authorservices.wiley.com/bauthor/onlineopen_order.asp

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

3.1 MANUSCRIPT SUBMISSION PROCEDURE

Manuscripts should be submitted electronically via the online submission site http://mc.manuscriptcentral.com/iej. The use of an online submission and peer review site enables immediate distribution of manuscripts and consequentially speeds up the review process. It also allows authors to track the status of their own manuscripts. Complete instructions for submitting a paper is available online and below. Further assistance can be obtained from iejeditor@cardiff.ac.uk.

3.2. Getting Started
• Launch your web browser (supported browsers include Internet Explorer 5.5 or higher, Safari 1.2.4, or Firefox 1.0.4 or higher) and go to the journal's online Submission Site: http://mc.manuscriptcentral.com/iej
• Log-in, or if you are a new user, click on 'register here'.
• If you are registering as a new user.
- After clicking on 'register here', enter your name and e-mail information and click 'Next'. Your e-mail information is very important.
- Enter your institution and address information as appropriate, and then click 'Next.'
- Enter a user ID and password of your choice (we recommend using your e-mail address as your user ID), and then select your areas of expertise. Click 'Finish'.
• If you are registered, but have forgotten your log in details, please enter your e-mail address under 'Password Help'. The system will send you an automatic user ID and a new temporary password.
•  Log-in and select 'Author Centre '

3.3. Submitting Your Manuscript
• After you have logged into your 'Author Centre', submit your manuscript by clicking on the submission link under 'Author Resources'.
• Enter data and answer questions as appropriate. You may copy and paste directly from your manuscript and you may upload your pre-prepared covering letter.
• Click the 'Next' button on each screen to save your work and advance to the next screen.
• You are required to upload your files.
- Click on the 'Browse' button and locate the file on your computer.
- Select the designation of each file in the drop down next to the Browse button.
- When you have selected all files you wish to upload, click the 'Upload Files' button.
• Review your submission (in HTML and PDF format) before completing your submission by sending it to the Journal. Click the 'Submit' button when you are finished reviewing.

3.4. Manuscript Files Accepted
Manuscripts should be uploaded as Word (.doc) or Rich Text Format (.rft) files (not write-protected) plus separate figure files. GIF, JPEG, PICT or Bitmap files are acceptable for submission, but only high-resolution TIF or EPS files are suitable for printing. The files will be automatically converted to HTML and PDF on upload and will be used for the review process. The text file must contain the abstract, main text, references, tables, and figure legends, but no embedded figures or Title page. The Title page should be uploaded as a separate file. In the main text, please reference figures as for instance 'Figure 1', 'Figure 2' etc to match the tag name you choose for the individual figure files uploaded. Manuscripts should be formatted as described in the Author Guidelines below.

3.5. Blinded Review
Manuscript that do not conform to the general aims and scope of the journal will be returned immediately without review. All other manuscripts will be reviewed by experts in the field (generally two referees). International Endodontic Journal aims to forward referees´ comments and to inform the corresponding author of the result of the review process. Manuscripts will be considered for fast-track publication under special circumstances after consultation with the Editor.
International Endodontic Journal uses double blinded review. The names of the reviewers will thus not be disclosed to the author submitting a paper and the name(s) of the author(s) will not be disclosed to the reviewers.
To allow double blinded review, please submit (upload) your main manuscript and title page as separate files.
Please upload:
• Your manuscript without title page under the file designation 'main document'
• Figure files under the file designation 'figures'
• The title page and Acknowledgements where applicable, should be uploaded under the file designation 'title page'
All documents uploaded under the file designation 'title page' will not be viewable in the html and pdf format you are asked to review in the end of the submission process. The files viewable in the html and pdf format are the files available to the reviewer in the review process.

3.6. Suspension of Submission Mid-way in the Submission Process
You may suspend a submission at any phase before clicking the 'Submit' button and save it to submit later. The manuscript can then be located under 'Unsubmitted Manuscripts' and you can click on 'Continue Submission' to continue your submission when you choose to.

3.7. E-mail Confirmation of Submission
After submission you will receive an e-mail to confirm receipt of your manuscript. If you do not receive the confirmation e-mail after 24 hours, please check your e-mail address carefully in the system. If the e-mail address is correct please contact your IT department. The error may be caused by some sort of spam filtering on your e-mail server. Also, the e-mails should be received if the IT department adds our e-mail server (uranus.scholarone.com) to their whitelist.

3.8. Manuscript Status
You can access ScholarOne Manuscripts any time to check your 'Author Centre' for the status of your manuscript. The Journal will inform you by e-mail once a decision has been made.

3.9. Submission of Revised Manuscripts
To submit a revised manuscript, locate your manuscript under 'Manuscripts with Decisions' and click on 'Submit a Revision'. Please remember to delete any old files uploaded when you upload your revised manuscript.

4. MANUSCRIPT TYPES ACCEPTED

Original Scientific Articles: must describe significant and original experimental observations and provide sufficient detail so that the observations can be critically evaluated and, if necessary, repeated. Original Scientific Articles must conform to the highest international standards in the field.

Review Articles: are accepted for their broad general interest; all are refereed by experts in the field who are asked to comment on issues such as timeliness, general interest and balanced treatment of controversies, as well as on scientific accuracy. Reviews should generally include a clearly defined search strategy and take a broad view of the field rather than merely summarizing the authors´ own previous work. Extensive or unbalanced citation of the authors´ own publications is discouraged.

Mini Review Articles: are accepted to address current evidence on well-defined clinical, research or methodological topics. All are refereed by experts in the field who are asked to comment on timeliness, general interest, balanced treatment of controversies, and scientific rigor. A clear research question, search strategy and balanced synthesis of the evidence is expected. Manuscripts are limited in terms of word-length and number of figures.

Clinical Articles: are suited to describe significant improvements in clinical practice such as the report of a novel technique, a breakthrough in technology or practical approaches to recognised clinical challenges. They should conform to the highest scientific and clinical practice standards.

Case Reports: illustrating unusual and clinically relevant observations are acceptable but they must be of sufficiently high quality to be considered worthy of publication in the Journal. On rare occasions, completed cases displaying non-obvious solutions to significant clinical challenges will be considered. Illustrative material must be of the highest quality and healing outcomes, if appropriate, should be demonstrated.

Supporting InformationInternational Endodontic Journal encourages submission of adjuncts to printed papers via the supporting information website (see submission of supporting information below). It is encouraged that authors wishing to describe novel procedures or illustrate cases more fully with figures and/or video may wish to utilise this facility.

Letters to the Editor: are also acceptable.

Meeting Reports: are also acceptable.

5. MANUSCRIPT FORMAT AND STRUCTURE

5.1. Format

Language: The language of publication is English. It is preferred that manuscript is professionally edited. A list of independent suppliers of editing services can be found at http://authorservices.wiley.com/bauthor/english_language.asp. All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication

Presentation: Authors should pay special attention to the presentation of their research findings or clinical reports so that they may be communicated clearly. Technical jargon should be avoided as much as possible and clearly explained where its use is unavoidable. Abbreviations should also be kept to a minimum, particularly those that are not standard. The background and hypotheses underlying the study, as well as its main conclusions, should be clearly explained. Titles and abstracts especially should be written in language that will be readily intelligible to any scientist.

Abbreviations: International Endodontic Journal adheres to the conventions outlined in Units, Symbols and Abbreviations: A Guide for Medical and Scientific Editors and Authors. When non-standard terms appearing 3 or more times in the manuscript are to be abbreviated, they should be written out completely in the text when first used with the abbreviation in parenthesis.

5.2. Structure
All manuscripts submitted to International Endodontic Journal should include Title Page, Abstract, Main Text, References and Acknowledgements, Tables, Figures and Figure Legends as appropriate

Title Page: The title page should bear:  (i) Title, which should be concise as well as descriptive; (ii) Initial(s) and last (family) name of each author; (iii) Name and address of department, hospital or institution to which work should be attributed; (iv) Running title (no more than 30 letters and spaces); (v) No more than six keywords (in alphabetical order); (vi) Name, full postal address, telephone, fax number and e-mail address of author responsible for correspondence.

Abstract for Original Scientific Articles should be no more than 250 words giving details of what was done using the following structure:

• Aim: Give a clear statement of the main aim of the study and the main hypothesis tested, if any.
• Methodology: Describe the methods adopted including, as appropriate, the design of the study, the setting, entry requirements for subjects, use of materials, outcome measures and statistical tests.
 Results: Give the main results of the study, including the outcome of any statistical analysis.
• Conclusions: State the primary conclusions of the study and their implications. Suggest areas for further research, if appropriate.

Abstract for Review Articles should be non-structured of no more than 250 words giving details of what was done including the literature search strategy.

Abstract for Mini Review Articles should be non-structured of no more than 250 words, including a clear research question, details of the literature search strategy and clear conclusions.

Abstract for Case Reports should be no more than 250 words using the following structure:

• Aim: Give a clear statement of the main aim of the report and the clinical problem which is addressed.
 Summary: Describe the methods adopted including, as appropriate, the design of the study, the setting, entry requirements for subjects, use of materials, outcome measures and analysis if any.
• Key learning points: Provide up to 5 short, bullet-pointed statements to highlight the key messages of the report. All points must be fully justified by material presented in the report.

Abstract for Clinical Articles should be no more than 250 words using the following structure:

• Aim: Give a clear statement of the main aim of the report and the clinical problem which is addressed.
• Methodology: Describe the methods adopted.
• Results: Give the main results of the study.
• Conclusions: State the primary conclusions of the study.

Main Text of Original Scientific Article should include Introduction, Materials and Methods, Results, Discussion and Conclusion

Introduction: should be focused, outlining the historical or logical origins of the study and gaps in knowledge.  Exhaustive literature reviews are not appropriate. It should close with the explicit statement of the specific aims of the investigation, or hypothesis to be tested.

Material and Methods: must contain sufficient detail such that, in combination with the references cited, all clinical trials and experiments reported can be fully reproduced.

(i) Clinical Trials should be reported using the CONSORT guidelines available at www.consort-statement.org. A CONSORT checklist and flow diagram (as a Figure) should also be included in the submission material.

(ii) Experimental Subjects: experimentation involving human subjects will only be published if such research has been conducted in full accordance with ethical principles, including the World Medical Association Declaration of Helsinki (version 2008) and the additional requirements, if any, of the country where the research has been carried out. Manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding and written consent of each subject and according to the above mentioned principles. A statement regarding the fact that the study has been independently reviewed and approved by an ethical board should also be included. Editors reserve the right to reject papers if there are doubts as to whether appropriate procedures have been used.

When experimental animals are used the methods section must clearly indicate that adequate measures were taken to minimize pain or discomfort. Experiments should be carried out in accordance with the Guidelines laid down by the National Institute of Health (NIH) in the USA regarding the care and use of animals for experimental procedures or with the European Communities Council Directive of 24 November 1986 (86/609/EEC) and in accordance with local laws and regulations.

All studies using human or animal subjects should include an explicit statement in the Material and Methods section identifying the review and ethics committee approval for each study, if applicable. Editors reserve the right to reject papers if there is doubt as to whether appropriate procedures have been used.

(iii) Suppliers: Suppliers of materials should be named and their location (Company, town/city, state, country) included.

Results: should present the observations with minimal reference to earlier literature or to possible interpretations. Data should not be duplicated in Tables and Figures.

Discussion: may usefully start with a brief summary of the major findings, but repetition of parts of the abstract or of the results section should be avoided. The Discussion section should progress with a review of the methodology before discussing the results in light of previous work in the field. The Discussion should end with a brief conclusion and a comment on the potential clinical relevance of the findings. Statements and interpretation of the data should be appropriately supported by original references.

Conclusion: should contain a summary of the findings.

Main Text of Review Articles should be divided into Introduction, Review and Conclusions. The Introduction section should be focused to place the subject matter in context and to justify the need for the review. The Review section should be divided into logical sub-sections in order to improve readability and enhance understanding. Search strategies must be described and the use of state-of-the-art evidence-based systematic approaches is expected. The use of tabulated and illustrative material is encouraged. The Conclusion section should reach clear conclusions and/or recommendations on the basis of the evidence presented.

Main Text of Mini Review Articles should be divided into Introduction, Review and Conclusions. The Introduction  section should briefly introduce the subject matter and justify the need and timeliness of the literature review. The Review section should be divided into logical sub-sections to enhance readability and understanding and may be supported by up to 5 tables and figures. Search strategies must be described and the use of state-of-the-art evidence-based systematic approaches is expected. The Conclusions section should present clear statements/recommendations and suggestions for further work. The manuscript, including references and figure legends should not normally exceed 4000 words.

Main Text of Clinical Reports and Clinical Articles should be divided into Introduction, Report, Discussion and Conclusion,. They should be well illustrated with clinical images, radiographs, diagrams and, where appropriate, supporting tables and graphs. However, all illustrations must be of the highest quality

Acknowledgements: International Endodontic Journal requires that all sources of institutional, private and corporate financial support for the work within the manuscript must be fully acknowledged, and any potential conflicts of interest noted. Grant or contribution numbers may be acknowledged, and principal grant holders should be listed. Acknowledgments should be brief and should not include thanks to anonymous referees and editors.  See also above under Ethical Guidelines.

5.3. References
It is the policy of the Journal to encourage reference to the original papers rather than to literature reviews. Authors should therefore keep citations of reviews to the absolute minimum.

We recommend the use of a tool such as EndNote or Reference Manager for reference management and formatting. The EndNote reference style can be obtained upon request to the editorial office (iejeditor@cardiff.ac.uk). Reference Manager reference styles can be searched for here: www.refman.com/support/rmstyles.asp

In the text: single or double authors should be acknowledged together with the year of publication, e.g. (Pitt Ford & Roberts 1990). If more than two authors the first author followed by et al. is sufficient, e.g. (Tobias et al. 1991). If more than 1 paper is cited the references should be in year order and separated by "," e.g. (Pitt Ford & Roberts 1990, Tobias et al. 1991).

Reference list: All references should be brought together at the end of the paper in alphabetical order and should be in the following form.

(i) Names and initials of up to six authors. When there are seven or more, list the first three and add et al.
(ii)Year of publication in parentheses
(iii) Full title of paper followed by a full stop (.)
(iv) Title of journal in full (in italics)
(v) Volume number (bold) followed by a comma (,)
(vi) First and last pages

Examples of correct forms of reference follow:

Standard journal article
Bergenholtz G, Nagaoka S, Jontell M (1991) Class II antigen-expressing cells in experimentally induced pulpitis. International Endodontic Journal 24, 8-14.

Corporate author
British Endodontic Society (1983) Guidelines for root canal treatment. International Endodontic Journal 16, 192-5.

Journal supplement
Frumin AM, Nussbaum J, Esposito M (1979) Functional asplenia: demonstration of splenic activity by bone marrow scan (Abstract). Blood 54 (Suppl. 1), 26a.

Books and other monographs

Personal author(s)
Gutmann J, Harrison JW (1991) Surgical Endodontics, 1st edn Boston, MA, USA: Blackwell Scientific Publications.

Chapter in a book
Wesselink P (1990) Conventional root-canal therapy III: root filling. In: Harty FJ, ed. Endodontics in Clinical Practice, 3rd edn; pp. 186-223. London, UK: Butterworth.

Published proceedings paper
DuPont B (1974) Bone marrow transplantation in severe combined immunodeficiency with an unrelated MLC compatible donor. In: White HJ, Smith R, eds. Proceedings of the Third Annual Meeting of the International Society for Experimental Rematology; pp. 44-46. Houston, TX, USA: International Society for Experimental Hematology.

Agency publication
Ranofsky AL (1978) Surgical Operations in Short-Stay Hospitals: United States-1975. DHEW publication no. (PHS) 78-1785 (Vital and Health Statistics; Series 13; no. 34.) Hyattsville, MD, USA: National Centre for Health Statistics.8

Dissertation or thesis
Saunders EM (1988) In vitro and in vivo investigations into root-canal obturation using thermally softened gutta-percha techniques (PhD Thesis). Dundee, UK: University of Dundee.

URLs
Full reference details must be given along with the URL, i.e. authorship, year, title of document/report and URL.  If this information is not available, the reference should be removed and only the web address cited in the text.
Smith A (1999) Select committee report into social care in the community [WWW document]. URL http://www.dhss.gov.uk/reports/report015285.html
[accessed on 7 November 2003]

5.4. Tables, Figures and Figure Legends

Tables
: Tables should be double-spaced with no vertical rulings, with a single bold ruling beneath the column titles. Units of measurements must be included in the column title.

Figures: All figures should be planned to fit within either 1 column width (8.0 cm), 1.5 column widths (13.0 cm) or 2 column widths (17.0 cm), and must be suitable for photocopy reproduction from the printed version of the manuscript. Lettering on figures should be in a clear, sans serif typeface (e.g. Helvetica); if possible, the same typeface should be used for all figures in a paper. After reduction for publication, upper-case text and numbers should be at least 1.5-2.0 mm high (10 point Helvetica). After reduction, symbols should be at least 2.0-3.0 mm high (10 point). All half-tone photographs should be submitted at final reproduction size. In general, multi-part figures should be arranged as they would appear in the final version. Reduction to the scale that will be used on the page is not necessary, but any special requirements (such as the separation distance of stereo pairs) should be clearly specified.

Unnecessary figures and parts (panels) of figures should be avoided: data presented in small tables or histograms, for instance, can generally be stated briefly in the text instead. Figures should not contain more than one panel unless the parts are logically connected; each panel of a multipart figure should be sized so that the whole figure can be reduced by the same amount and reproduced on the printed page at the smallest size at which essential details are visible.

Figures should be on a white background, and should avoid excessive boxing, unnecessary colour, shading and/or decorative effects (e.g. 3-dimensional skyscraper histograms) and highly pixelated computer drawings. The vertical axis of histograms should not be truncated to exaggerate small differences. The line spacing should be wide enough to remain clear on reduction to the minimum acceptable printed size.

Figures divided into parts should be labelled with a lower-case, boldface, roman letter, a, b, and so on, in the same typesize as used elsewhere in the figure. Lettering in figures should be in lower-case type, with the first letter capitalized. Units should have a single space between the number and the unit, and follow SI nomenclature or the nomenclature common to a particular field. Thousands should be separated by a thin space (1 000). Unusual units or abbreviations should be spelled out in full or defined in the legend. Scale bars should be used rather than magnification factors, with the length of the bar defined in the legend rather than on the bar itself. In general, visual cues (on the figures themselves) are preferred to verbal explanations in the legend (e.g. broken line, open red triangles etc.)

Figure legends: Figure legends should begin with a brief title for the whole figure and continue with a short description of each panel and the symbols used; they should not contain any details of methods.

Permissions: If all or part of previously published illustrations are to be used, permission must be obtained from the copyright holder concerned. This is the responsibilty of the authors before submission.

Preparation of Electronic Figures for Publication: Although low quality images are adequate for review purposes, print publication requires high quality images to prevent the final product being blurred or fuzzy. Submit EPS (lineart) or TIFF (halftone/photographs) files only. MS PowerPoint and Word Graphics are unsuitable for printed pictures. Do not use pixel-oriented programmes. Scans (TIFF only) should have a resolution of 300 dpi (halftone) or 600 to 1200 dpi (line drawings) in relation to the reproduction size (see below). EPS files should be saved with fonts embedded (and with a TIFF preview if possible). For scanned images, the scanning resolution (at final image size) should be as follows to ensure good reproduction: lineart:  >600 dpi; half-tones (including gel photographs): >300 dpi; figures containing both halftone and line images: >600 dpi.

Further information can be obtained at Wiley Blackwell’s guidelines for figures: http:/authorservices.wiley.com/bauthor/illustration.asp.

Check your electronic artwork before submitting it: http://authorservices.wiley.com/bauthor/eachecklist.asp.

5.5. Supporting Information 
Publication in electronic formats has created opportunities for adding details or whole sections in the electronic version only. Authors need to work closely with the editors in developing or using such new publication formats.

Supporting information, such as data sets or additional figures or tables, that will not be published in the print edition of the journal, but which will be viewable via the online edition, can be submitted. It should be clearly stated at the time of submission that the supporting information is intended to be made available through the online edition. If the size or format of the supporting information is such that it cannot be accommodated on the journal's website, the author agrees to make the supporting information available free of charge on a permanent Web site, to which links will be set up from the journal's website. The author must advise Wiley Blackwell if the URL of the website where the supporting information is located changes. The content of the supporting information must not be altered after the paper has been accepted for publication.

The availability of supporting information should be indicated in the main manuscript by a paragraph, to appear after the References, headed 'Supporting Information' and providing titles of figures, tables, etc. In order to protect reviewer anonymity, material posted on the authors Web site cannot be reviewed. The supporting information is an integral part of the article and will be reviewed accordingly.

Preparation of Supporting Information: Although provision of content through the web in any format is straightforward, supporting information is best provided either in web-ready form or in a form that can be conveniently converted into one of the standard web publishing formats:

• Simple word-processing files (.doc or .rtf) for text.
• PDF for more complex, layout-dependent text or page-based material. Acrobat files can be distilled from Postscript by the Publisher, if necessary.
• GIF or JPEG for still graphics. Graphics supplied as EPS or TIFF are also acceptable.
• MPEG or AVI for moving graphics.

Subsequent requests for changes are generally unacceptable, as for printed papers. A charge may be levied for this service.

Video Imaging: For the on-line version of the Journal the submission of illustrative video is encouraged. Authors proposing the use such media should consult with the Editor during manuscript preparation.

6. AFTER ACCEPTANCE

Upon acceptance of a paper for publication, the manuscript will be forwarded to the Production Editor who is responsible for the production of the journal.

6.1. Figures
Hard copies of all figures and tables are required when the manuscript is ready for publication. These will be requested by the Editor when required. Each Figure copy should be marked on the reverse with the figure number and the corresponding author’s name.

6.2 Proof Corrections
The corresponding author will receive an email alert containing a link to a web site.  A working email address must therefore be provided for the corresponding author.  The proof can be downloaded as a PDF (portable document format) file from this site. Acrobat Reader will be required in order to read this file. This software can be downloaded (free of charge) from the following Web site: www.adobe.com/products/acrobat/readstep2.html. This will enable the file to be opened, read on screen, and printed out in order for any corrections to be added. Further instructions will be sent with the proof. Hard copy proofs will be posted if no e-mail address is available; in your absence, please arrange for a colleague to access your e-mail to retrieve the proofs. Proofs must be returned to the Production Editor within three days of receipt. As changes to proofs are costly, we ask that you only correct typesetting errors. Excessive changes made by the author in the proofs, excluding typesetting errors, will be charged separately. Other than in exceptional circumstances, all illustrations are retained by the publisher. Please note that the author is responsible for all statements made in his work, including changes made by the copy editor.

6.3 Early Online Publication Prior to Print
International Endodontic Journal is covered by Wiley Blackwell's Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so Early View articles cannot be cited in the traditional way. They are therefore given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before it is allocated to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article.

6.4 Online Production Tracking
Online production tracking is available for your article through Blackwell's Author Services. Author Services enables authors to track their article - once it has been accepted - through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production. The author will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit http://authorservices.wiley.com/bauthor/ for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

6.5 Author Material Archive Policy
Please note that unless specifically requested, Wiley Blackwell will dispose of all hardcopy or electronic material submitted two months after publication. If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible.

6.6 Offprints
Free access to the final PDF offprint of your article will be available via Author Services only. Please therefore sign up for Author Services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers.

Additional paper offprints may be ordered online. Please click on the following link, fill in the necessary details and ensure that you type information in all of the required fields: Offprint Cosprinters. If you have queries about offprints please email offprint@cosprinters.com

The corresponding author will be sent complimentary copies of the issue in which the paper is published (one copy per author).

6.7 Author Services
For more substantial information on the services provided for authors, please see Wiley Blackwell Author Services

6.8 Note to NIH Grantees: Pursuant to NIH mandate, Wiley Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance.  This accepted version will be made publicly available 12 months after publication.  For further information, see www.wiley.com/go/nihmandate

7 Guidelines for reporting of DNA microarray data
The International Endodontic Journal gives authors notice that, with effect from 1st January 2011, submission to the International Endodontic Journal requires the reporting of microarray data to conform to the MIAME guidelines. After this date, submissions will be assessed according to MIAME standards. The complete current guidelines are available at http://www.mged.org/Workgroups/MIAME/miame_2.0.html. Also, manuscripts will be published only after the complete data has been submitted into the public repositories, such as GEO (http://www.ncbi.nlm.nih.gov/geo/) or ArrayExpress (http://www.ebi.ac.uk/microarray/submissions_overview.html), in MIAME compliant format, with the data accession number (the identification number of the data set in the database) quoted in the manuscript. Both databases are committed to keeping the data private until the associated manuscript is published, if requested.

Prospective authors are also encouraged to search for previously published microarray data with relevance to their own data, and to report whether such data exists. Furthermore, they are encouraged to use the previously published data for qualitative and/or quantitative comparison with their own data, whenever suitable. To fully acknowledge the original work, an appropriate reference should be given not only to the database in question, but also to the original article in which the data was first published. This open approach will increase the availability and use of these large-scale data sets and improve the reporting and interpretation of the findings, and in increasing the comprehensive understanding of the physiology and pathology of endodontically related tissues and diseases, result eventually in better patient care.

 

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