Journal of Internal Medicine

Cover image for Vol. 276 Issue 5

Edited By: Ulf de Faire

Impact Factor: 5.785

ISI Journal Citation Reports © Ranking: 2013: 13/150 (Medicine General & Internal)

Online ISSN: 1365-2796

HOT TOPICS

  • The emerging role of microRNAs in cardiovascular disease

    The emerging role of microRNAs in cardiovascular disease

    This review focuses on main and repeated discoveries regarding the role and the therapeutic and biomarker feasibility of microRNAs during cardiovascular disease development and exacerbation.

  • Vitamin D and cognition in older adults’: updated international recommendations

    Vitamin D and cognition in older adults’: updated international recommendations

    The international task force agreed on five overarching principles related to vitamin D and cognition in older adults.

  • STED microscopy: increased resolution for medical research?

    STED microscopy: increased resolution for medical research?

    This review aims to highlight promising developments in and applications of STED microscopy and their impact on unresolved issues in biomedical science

  • Review of 103 Swedish Healthcare Quality Registries

    Review of 103 Swedish Healthcare Quality Registries

    This review describes the purpose, organization, variables, coverage and completeness of 103 Swedish QRs.

  • The challenge of intratumour heterogeneity in precision medicine

    The challenge of intratumour heterogeneity in precision medicine

    Cells within tumours have diverse genomes and epigenomes and interact differentially with their surrounding microenvironment generating intratumour heterogeneity, which has critical implications for treating cancer patients.

  • Glioma stem cells: turpis omen in nomen? (the evil in the name?)

    Glioma stem cells: turpis omen in nomen? (the evil in the name?)

    High-grade gliomas remain incurable and lethal. Through the availability of the stem-like cells responsible for glioblastoma (GB) formation, expansion, resilience and recurrence, the discovery of glioma cancer stem cells (GCSCs) is revolutionizing this field.

  • Metabolic regulation of stem cell function

    Metabolic regulation of stem cell function

    Stem cell function is regulated by intrinsic mechanisms, such as transcriptional and epigenetic regulators, as well as extrinsic mechanisms, such as short-range signals from the niche and long-range humoral signals. Interactions between these regulatory mechanisms and cellular metabolism are just beginning to be identified.

  • Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

    Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

    The aim of this review is to summarize an evolution of thinking about the epigenetic basis of human cancer, from the earliest studies of altered DNA methylation in cancer to the modern comprehensive epigenomic era

  • The emerging role of microRNAs in cardiovascular disease
  • Vitamin D and cognition in older adults’: updated international recommendations
  • STED microscopy: increased resolution for medical research?
  • Review of 103 Swedish Healthcare Quality Registries
  • The challenge of intratumour heterogeneity in precision medicine
  • Glioma stem cells: turpis omen in nomen? (the evil in the name?)
  • Metabolic regulation of stem cell function
  • Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

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JOURNAL INFORMATION

Journal of Internal Medicine (JIM) publishes original clinical work within the broad field of general and internal medicine and its sub-specialties. It features original articles, reviews, and case reports. JIM also supports and organizes scientific meetings in the form of symposia within the scope of the journal.

JIM presents the 9th Key Symposium: Updating Alzheimer's Disease Diagnosis

JIM presents the 10th Key Symposium: Taming the cancer cell

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Recently Published Articles

  1. Measurement of myocardial amyloid deposition in systemic amyloidosis: insights from cardiovascular magnetic resonance imaging

    Andrea Barison, Giovanni Donato Aquaro, Nicola Riccardo Pugliese, Francesco Cappelli, Sara Chiappino, Giuseppe Vergaro, Gianluca Mirizzi, Giancarlo Todiere, Claudio Passino, Pier Giorgio Masci, Federico Perfetto and Michele Emdin

    Accepted manuscript online: 24 OCT 2014 06:32AM EST | DOI: 10.1111/joim.12324

  2. You have free access to this content
    High-mobility group box-1 in sterile inflammation (pages 425–443)

    A. Tsung, S. Tohme and T. R. Billiar

    Article first published online: 24 OCT 2014 | DOI: 10.1111/joim.12276

  3. You have free access to this content
  4. Personalized medicine approaches in epilepsy

    L. E. Walker, N. Mirza, V. L. M. Yip, A. G. Marson and M. Pirmohamed

    Accepted manuscript online: 23 OCT 2014 04:00AM EST | DOI: 10.1111/joim.12322

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