Journal of Internal Medicine

Cover image for Vol. 276 Issue 4

Edited By: Ulf de Faire

Impact Factor: 5.785

ISI Journal Citation Reports © Ranking: 2013: 13/150 (Medicine General & Internal)

Online ISSN: 1365-2796

HOT TOPICS

  • Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival

    Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival

    Snus is a moist smokeless tobacco product with high nicotine content. Its use has a short-term effect on the cardiovascular system, but the relationship between snus use and stroke is unclear.

  • Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort

    Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort

    The results of this study provide observational evidence that avoiding sun exposure is a risk factor for all-cause mortality.

  • The challenge of intratumour heterogeneity in precision medicine

    The challenge of intratumour heterogeneity in precision medicine

    Cells within tumours have diverse genomes and epigenomes and interact differentially with their surrounding microenvironment generating intratumour heterogeneity, which has critical implications for treating cancer patients.

  • Glioma stem cells: turpis omen in nomen? (the evil in the name?)

    Glioma stem cells: turpis omen in nomen? (the evil in the name?)

    High-grade gliomas remain incurable and lethal. Through the availability of the stem-like cells responsible for glioblastoma (GB) formation, expansion, resilience and recurrence, the discovery of glioma cancer stem cells (GCSCs) is revolutionizing this field.

  • Metabolic regulation of stem cell function

    Metabolic regulation of stem cell function

    Stem cell function is regulated by intrinsic mechanisms, such as transcriptional and epigenetic regulators, as well as extrinsic mechanisms, such as short-range signals from the niche and long-range humoral signals. Interactions between these regulatory mechanisms and cellular metabolism are just beginning to be identified.

  • Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

    Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

    The aim of this review is to summarize an evolution of thinking about the epigenetic basis of human cancer, from the earliest studies of altered DNA methylation in cancer to the modern comprehensive epigenomic era

  • RAPID COMMUNICATION: Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism by X. Hu et al.

    RAPID COMMUNICATION: Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism by X. Hu et al.

    Data in this article show that the phenotype of AMP-treated wild-type mice resembles that of Cyp8b1−/− mice with fourfold induced Cyp7a1 expression, increased intestinal apical sodium-dependent BA transporter expression and increased hepatic BA levels...

  • Snus (Swedish smokeless tobacco) use and risk of stroke: pooled analyses of incidence and survival
  • Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort
  • The challenge of intratumour heterogeneity in precision medicine
  • Glioma stem cells: turpis omen in nomen? (the evil in the name?)
  • Metabolic regulation of stem cell function
  • Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine
  • RAPID COMMUNICATION: Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism by X. Hu et al.

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JOURNAL INFORMATION

Journal of Internal Medicine (JIM) publishes original clinical work within the broad field of general and internal medicine and its sub-specialties. It features original articles, reviews, and case reports. JIM also supports and organizes scientific meetings in the form of symposia within the scope of the journal.

JIM presents the 9th Key Symposium: Updating Alzheimer's Disease Diagnosis

JIM presents the 10th Key Symposium: Taming the cancer cell

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Recently Published Articles

  1. You have free access to this content
  2. Cardiovascular system participation in Alzheimer's disease pathogenesis

    Alex E. Roher

    Accepted manuscript online: 22 SEP 2014 11:16AM EST | DOI: 10.1111/joim.12311

  3. The autoimmune spectrum of myasthenia gravis: a Swedish population-based study

    F. Fang, O. Sveinsson, G. Thormar, M. Granqvist, J. Askling, I. E. Lundberg, W. Ye, L. Hammarström, R. Pirskanen and F. Piehl

    Accepted manuscript online: 22 SEP 2014 11:16AM EST | DOI: 10.1111/joim.12310

  4. You have free access to this content
  5. You have free access to this content

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