Journal of Internal Medicine

Cover image for Vol. 281 Issue 4

Edited By: Editor-in-Chief: Ulf de Faire

Impact Factor: 7.803

ISI Journal Citation Reports © Ranking: 2015: 10/155 (Medicine General & Internal)

Online ISSN: 1365-2796

HOT TOPICS

  • Role of autophagy in HIV infection and pathogenesis

    Role of autophagy in HIV infection and pathogenesis

    Regulation of the autophagic process. The major protein complexes involved in the regulation of the different steps of autophagy are shown. The roles of the indicated proteins in the autophagic process are described in the text. PI, phosphatidylinositol; PI3P, phosphatidylinositol 3-phosphate; P, phosphorylation; Ub, ubiquitination.

  • Organic bioelectronics in medicine

    Organic bioelectronics in medicine

    The organic biomimetic nerve cell is based on the organic electronic ion pump (OEIP) technology. a) Electrophoretic ion transport in the OEIP is achieved with electronic control. One ion is transported per electronic charge equivalent without mechanical disturbance or liquid flow. Modified from . b) A biosensor complements the OEIP to fulfil the basic functionality of a nerve cell: chemical sensing, electrical signal processing/transmission and chemical delivery. The working principle of the organic biomimetic nerve cell has been demonstrated for localized glutamate (Glu) sensing and acetylcholine (ACh) delivery (c) and remote ACh sensing and release (d). b–d modified from .

  • Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence

    Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence

    Distinct types of sensory neurons innervate the gastrointestinal tract and mediate different functional outcomes. Three sensory neuron types innervate the gastrointestinal tract and are able to respond to various environmental and internal stimuli. The sensory neurons of the enteric nervous system, termed intrinsic primary afferent neurons (IPANs), have cell bodies in the myenteric and submucosal plexus layers of the gut. They form complete reflex circuits with enteric interneurons and motor neurons to regulate many aspects of digestive and gastrointestinal functions such as gut motility, blood flow, fluid transport, and secretion. The gut receives extrinsic innervation by sensory afferents from the dorsal root ganglia (DRGs) that mediate visceral pain, pressure, and neurogenic inflammation. The gut also receives extrinsic innervation by sensory afferents from the nodose/jugular ganglia, mediating satiety, nausea, gut homeostasis, and inflammatory reflex circuits. Therefore, sensory information from the gut is differentially processed by distinct neuronal types, resulting in different gastrointestinal sensations and functional outcomes. CNS, central nervous system.

  • Management of acute ischaemic stroke in patients with dementia

    Management of acute ischaemic stroke in patients with dementia

    The association between stroke and dementia: underlying mechanisms.

  • Roles of the gut in the metabolic syndrome: an overview

    Roles of the gut in the metabolic syndrome: an overview

    The principal bariatric procedures.

  • Role of autophagy in HIV infection and pathogenesis
  • Organic bioelectronics in medicine
  • Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence
  • Management of acute ischaemic stroke in patients with dementia
  • Roles of the gut in the metabolic syndrome: an overview

Recently Published Issues

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14th Key Symposium 2017

We are pleased to announce that the next Key Symposium will focus on metabolic complications of obesity and will take place on 20-22 September 2017 in Cambridge, UK.

We will provide more information on the Key Symposia page shortly and hope to see you there.



Conference Reports

As of 2015, JIM publishes conference reports from our symposia. Please find the most recent below:

13th Key Symposium 2016
Guest Editors: Peder S. Olofsson and Kevin J. Tracey
21-23 September 2016
New York Academy of Sciences, NY, USA

Targeted therapy in B-cell malignancies
Guest Editor: Karin Ekström Smedby
29-30 September 2016
Nobel Forum, Karolinska Institutet, Stockholm, Sweden

For more information on upcoming and past symposia, please click here

Journal Information

With an Impact Factor of 7.803, Journal of Internal Medicine now ranks 10th among the 151 journals in the General & Internal Medicine category.

Established in 1863.

Features original clinical articles within the broad field of general and internal medicine and its sub-specialties.

A fully international journal publishing articles in English from all over the world.

Peer-reviewed and published in both print and online versions.

JIM also supports and organizes scientific meetings in the form of symposia within the scope of the journal.


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13th Key Symposium

Read more

The 13th Key Symposium: Bioelectronic Medicine: technology targeting molecular mechanisms was supported by JIM Journal of Internal Medicine and took place in September 2016. You can find a short video from the symposium below

Articles from this meeting will be published in JIM.

You can also find more videos and podcasts from previous symposia on JIM Multimedia Resources.

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