Journal of Internal Medicine

Cover image for Vol. 278 Issue 2

Edited By: Ulf de Faire

Impact Factor: 6.063

ISI Journal Citation Reports © Ranking: 2014: 12/153 (Medicine General & Internal)

Online ISSN: 1365-2796

HOT TOPICS

  • The WNT system: background and its role in bone

    The WNT system: background and its role in bone

    This review provides the historical background to the discoveries of WNTs, describes the different WNT signalling pathways and summarizes the current understanding of how these proteins regulate bone mass by affecting bone formation and resorption.

  • Osteoporosis: the evolution of a diagnosis

    Osteoporosis: the evolution of a diagnosis

    The global trend towards increased longevity has resulted in ageing populations and a rise in diseases or conditions that primarily affect older persons. One such condition is osteoporosis and the review covers the evolution of a diagnosis.

  • Osteoporosis: the emperor has no clothes

    Osteoporosis: the emperor has no clothes

    Current prevention strategies for low-trauma fractures amongst older persons depend on the notions that fractures are mainly caused by osteoporosis (pathophysiology), that patients at high risk can be identified (sreening) and that the risk is amenable to bone-targeted pharmacotherapy (treatment). However, all these three notions can be disputed.

  • Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A

    Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A

    Understanding the mechanism by which bone marrow mesenchymal stem cells (BMSCs) differentiate into bone-forming osteoblasts and marrow adipocytes is crucial to develop strategies for the treatment of several bone diseases.

  • Bone and the regulation of global energy balance

    Bone and the regulation of global energy balance

    In this review, we highlight recent studies in this field and offer a perspective on the evolutionary implications of bone as a metabolic endocrine organ.

  • Efficacy, effectiveness and side effects of medications used to prevent fractures

    Efficacy, effectiveness and side effects of medications used to prevent fractures

    Reappraisal of ongoing use of bisphosphonates after about 5 years is endorsed by expert consensus, and 'drug holidays' should be considered at this time.

  • Bone research: an issue of maturity

    Bone research: an issue of maturity

    Osteoporosis was once regarded as a natural part of ageing, with fragility fractures as a severe manifestation that at best could be treated by orthopaedic surgeons. During the last few decades, the field of bone research has developed substantially.

  • The WNT system: background and its role in bone
  • Osteoporosis: the evolution of a diagnosis
  • Osteoporosis: the emperor has no clothes
  • Regulation of adipogenesis and osteogenesis in mesenchymal stem cells by vascular endothelial growth factor A
  • Bone and the regulation of global energy balance
  • Efficacy, effectiveness and side effects of medications used to prevent fractures
  • Bone research: an issue of maturity

Recently Published Issues

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Conference Report

As of 2015, JIM publishes conference reports from our symposia. Please find the most recent below:

Nobel Minisymposium in the series 'Frontiers in Medicine'
Amyloid - a multifaceted player in human health and disease

10-11 June 2015
Guest Editor: Jan Johansson
Nobel Forum, Karolinska Institutet, Stockholm, Sweden

Endocrine tumors - new generation sequencing with impact on therapy
4-5 June 2015
Guest Editor: Göran Åkerström
Blåsenhus, Uppsala, Sweden

For more information on upcoming and past symposia, please click here

Journal information

Journal of Internal Medicine (JIM) publishes original clinical work within the broad field of general and internal medicine and its sub-specialties. It features original articles, reviews, and case reports. JIM also supports and organizes scientific meetings in the form of symposia within the scope of the journal.

JIM presents the 11th Key Symposium: Osteoporosis: the emperor has no clothes

JIM presents the 11th Key Symposium: Osteoporosis: the evolution of a diagnosis

JIM presents the 11th Key Symposium: Regulation of adipogenesis and osteogenesis

JIM presents the 11th Key Symposium: Molecular and clinical prediction of the risk for osteoporotic fractures

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