Journal of Internal Medicine

Cover image for Vol. 277 Issue 1

Edited By: Ulf de Faire

Impact Factor: 5.785

ISI Journal Citation Reports © Ranking: 2013: 13/150 (Medicine General & Internal)

Online ISSN: 1365-2796

Author Guidelines

The Journal of Internal Medicine (JIM) publishes Original Articles on clinical and experimental research related to the broad field of medicine. JIM also welcomes Review Articles at the forefront of science and research in medicine, and also supports and organizes Workshops and Symposia on topics within the scope of the journal. Case reports on unique clinical observations may also be considered but only exceptionally.

Editorials, Letters to the Editor and Consensus Reports are also published after commission by the Editors.

Correspondence to the journal is accepted on the understanding that the contributing author licenses the Publisher to publish the letter as part of the journal or separately from it, in the exercise of any subsidiary rights relating to the journal and its contents.

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

Online production tracking is available for your article through Author Services
Author Services enables authors to track their article - once it has been accepted - through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production. The author will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit Author Services  for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

Accepted Articles
Journal of Internal Medicine  now offers Accepted Articles for all articles within a short time of acceptance.

Accepted Articles is a service whereby peer reviewed, accepted articles are published online as and when they are ready, prior to their ultimate inclusion in a print or online issue and without having been copy-edited. It has been designed to ensure the ealiest possible circulation of research papers after acceptance. Readers should note that all articles published within Accepted Articles have been fully refereed, but have not been through the copy-editing and proof correction process. Wiley cannot be held responsible for errors or consequences arising from the use of information contained in these articles; nor do the views and opinions expressed necessarily reflect those of Wiley.

Accepted Articles appear in PDF-only format, without the accompanying full-text HTML. Accepted Articles are fully citable using the DOI number.

Ethical Guidelines
Submission is considered on the conditions that papers are previously unpublished, and are not offered simultaneously elsewhere; that authors have read and approved the content, and all authors have also declared all competing interests; and that the work complies with the Ethical Policies of the Journal and has been conducted under internationally accepted ethical standards after relevant ethical review.

Plagiarism and misconduct
Journal of Internal Medicine is a member of COPE (Committee of Publication Ethics) and follows strictly its Code of Conduct for Journal Editors. This implies that if the Editors suspect research misconduct, the article in question will be held in abeyance until this matter is resolved. The Editors will contact authors and any appropriate third party to ascertain whether the grounds for investigation are justified.

If a paper that has been published is found to be fraudulent in some manner, it will be retracted and appropriate steps will be taken to notify readers of the journal, and the authors’ institution. Retractions will include the word ‘Retraction’ in the title, so that they are identified as such on indexing systems, for example, PubMed.

In any case of serious research misconduct, all authors of such an article may be banned from future publication in Journal of Internal Medicine.

Submission of manuscripts

Pre-submission English-language editing. Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. English-language editing will a) improve grammar, spelling, and punctuation; b) improve clarity and resolve any ambiguity caused by poor phrasing and c) improve word choice and ensure that the tone of the language is appropriate for an academic journal. A list of independent suppliers of editing services can be found at All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.

Manuscripts should be submitted online at Manuscript Central. Full instructions and support are available at the site. A user ID and password can be obtained on the first visit. All parts of the manuscript must be available in an electronic format. Those recommended are: Microsoft Word or generic RTF for text, and JPEG, GIF, TIFF, EPS, PNG, Microsoft PowerPoint or Excel for graphics (see section Tables and figures).To be considered for publication the author should provide suggestions for at least four reviewers. It is recommended that, where possible, figures and tables be placed within a single word processor file. Apple Macintosh users should ensure compatibility by submitting files with correct PC filename suffixes (e.g. ‘.doc’ for Microsoft Word). Support can be contacted by phone ( 1 434-817-2040 ext 167), e-mail ( or go to If you cannot submit online please contact the Editorial Office ( or write to:

Journal of Internal Medicine
Buildg. X5:01 (Borgmastarvillan)
Karolinska University Hospital, Solna,
Karolinska vagen 29
SE-171 76 Stockholm

All material should conform to Uniform Requirements for Manuscripts Submitted to Biomedical Journals. The latest version of the rules of the International Committee of Medical Journal Editors (The Vancouver Group) may be found in Medical Education 1999; 33: 66-78. All Manuscripts should be witten in British english. Use only few abbreviations. an abbreviation list should be included, if needed.

The SI system must be used; for guidance see Units, Symbols, and Abbreviations 4th edn. (London: Royal Society of Medicine Services, 1988).

Covering letter

All authors must give signed consent to publication in a covering letter including the following information. (i) A statement that the manuscript has not been published elsewhere, and that, if accepted in JIM, will not be republished in any other journal in the same or similar form without the written consent of the Editor of JIM and Wiley. Written permission must be obtained from the copyright holder for reproduction of figures published elsewhere. (ii) A statement of financial or other relationships that might lead to a conflict of interest. (iii) A statement that the manuscript has been read and approved by all authors.

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and Wiley Open Access.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) or the Austrian Science Fund (FWF) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with your Funder requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: here.

OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. Please click here for further information about OnlineOpen.

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

All reviews and linked articles are Free Access on Wiley Online Library for the Journal of Internal Medicine. However authors of free access articles can choose OnlineOpen status for their respective articles as well. A brief summary of the difference between Free Access and OnlineOpen is as follows:

Free Access: Freely available to all on Wiley Online Library, including those who don't subscribe to the journal.

OnlineOpen: Freely available to all on Wiley Online Library, including those who don't subscribe to the journal-- In addition, authors of OnlineOpen articles are permitted to post the final, published PDF of their article on a website, institutional repository or other free public server, immediately on publication. Wiley will also immediately deposit your OnlineOpen article in PubMed Central and PMC mirror sites. Authors keep copyright of article.

Author material archive policy
Please note that unless specifically requested, Wiley will dispose of all hardcopy or electronic material submitted, two months after publication. If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible if you have not yet done so.

Arrangement of the manuscripts
All pages (including references, tables and their captions, figure captions and [where possible] figures) should be saved in a single electronic file.

The manuscript should include the following: (i) title page, (ii) abstract, (iii) main text (introduction, materials and methods, results, discussion), (iv) references, (v) figure legends, (vi) tables, (vii) figures.

Title page
The first page should contain: title of paper, suggested running headline of not more than 30 characters (including both letters and spaces) and author's name, department, institution, city and country.

The limit for Case Reports is 100 words, for all other manuscript types the limit is 250 words. For Original articles, the abstract should include headings and be structured. For Review articles, the abstract should be a concise summary of the results presented and reviewed. Ideally, this abstract should also include keywords to help those interested in the topic to find the review.

The title should be informative, rather than descriptive, and clearly state the key message of the paper. It should also preferably be a full sentence.

Give a clear statement of the main aim of the study and the main hypothesis tested, if any.

Describe the design of the study and mention, as appropriate, randomization, blinding, placebo-control, case-control, cross-over, criterion standards for diagnostic tests, and so on.

Describe the setting of the study, including the level of clinical care (primary care, etc.) and the number of participating centres.

State the entry requirements, selection procedures and the number of subjects approached, entering and completing the study.

Describe the main features of any interventions, including the method and duration of their use.

Main outcome measures. State the primary outcome measures as planned before the data were collected. If the paper does not emphasize the planned main outcome measures, this should be stated and explained.

Give the main results of the study.

State the primary conclusions of the study and their clinical implications. Suggest areas for further research, if appropriate.

We encourage the authors to list at least two, but no more than six keywords below the abstract. Preferably use the keywords listed at, or use terms from the 'Medical Subject Headings' list from Index Medicus.

Ethical considerations
For studies involving ethical problems approval by the local ethical authority should be indicated in the 'Material and methods' section.

Conflict of Interest Statement
A statement of financial or other relationship that might lead to a conflict of interest should be declared.  It should also be stated if you have nothing to declare.

Financial support, technical and other assistance of importance for the study may be acknowledged.

We recommend the use of a tool such as Reference Manager for reference management and formatting. Reference Manager reference styles can be searched for here.

Number references consecutively in the order in which they are first mentioned in the text. Identify references in text, tables and captions by Arabic numerals in [square] brackets. Use the references form adopted by the US National Library of Medicine. Titles of journals should be abbreviated according to the style used in Index Medicus. In the list, reference can be made only to published or accepted articles, not to unpublished or submitted work - these should, if necessary, be referred to in full within parentheses in the text.

List all authors when seven or less; when more, give three followed by et al.

Examples of correct forms of references are given below.

1 Standard journal article
Carlson LA, Hamsten A, Asplund A. Pronounced lowering of serum levels of lipoprotein Lp(a) in hyperlipidaemic subjects treated with nicotinic acid. J Intern Med 1989; 226: 271-6.

2 Chapter in book
Weinstein L, Swartz MN. Pathogenic properties of invading microorganisms. In: Sodeman WA Jr, Sodeman WA, eds, Pathologic Physiology: Mechanisms of Disease. Philadelphia: W. B. Saunders. 1974; 457-72.

Correspondence address
The last page of the reference list should carry the name and address of the author to whom correspondence, including requests for offprints, should be sent. Telephone and fax numbers (as well as an e-mail address if available) should also be given. (The responsible author is advised to have an alternative proof reader amongst the coauthors; give the name and address of this 'second' author here.)

Tables and figures
Figure captions should follow the correspondence address and must be comprehensive so that they are understandable without reference to the text. All figures should be cited in the text. Authors are encouraged to submit figures in colour where appropriate. Further information on preparing high-resolution digital files can be found at In case of use of a previously published table, figure or illustration, written permission from the publisher should be submitted with the manuscript.

In the full-text online edition of the journal, figure legends may be truncated in abbreviated links to the full screen version. Therefore the first 100 characters of any legend should inform the reader of key aspects of the figure.

Tables should follow the figure legends. Only horizontal lines should be used.

Note to NIH Grantees
Pursuant to NIH mandate,Wiley will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information, see

The corresponding author will receive an email alert containing a link to a web site. A working e-mail address must therefore be provided for the corresponding author. The proof can be downloaded as a PDF (portable document format) file from this site. Acrobat Reader will be required in order to read this file. This software can be downloaded (free of charge) from Adobe.

This will enable the file to be opened, read on screen and printed out in order for any corrections to be added. Further instructions will be sent with the proof. Hard copy proofs will be posted if no e-mail address is available. Excessive changes made by the author in the proofs, excluding typesetting errors, will be charged separately. Upon online publication, the Journal of Internal Medicine gives free access to the PDF file of the final, published article. In order to get access, you must register at our Author Services website. NOTE: Free access to the final PDF offprint or your article will be available via Author Services only. Therefore, please sign up for Author Services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers.

Upon online publication, the Journal of Internal Medicine gives free access to the PDF file of the final, published article. In order to get access, you must register at our Author Services website. NOTE: Free access to the final PDF offprint or your article will be available via Author Services only. Therefore, please sign up for author services if you would like to access your article PDF offprint and enjoy the many other benefits the service offers.

Review and Action
Manuscripts are examined by the editorial group and are usually sent to outside reviewers. To be considered for publication the author should suggest at least four reviewers.

Rapid Communication

Concise papers (not exceeding 1500 words) representing new but completed work which is of unusually high priority and significance, as clearly indicated by the authors in the covering letter, will be considered as Rapid communications. Papers will be reviewed immediately and publication should occur within 8 weeks of acceptance of the manuscript, with a few exceptions.

Further Information
For more information please contact the Editorial Office in Stockholm (e-mail: