Journal of Viral Hepatitis

Cover image for Vol. 21 Issue 8

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Editor-In-Chief: Graham Foster US Editor: Nezam Afdhal European Editors: Peter Karayiannis and Mark Thursz

Impact Factor: 3.082

ISI Journal Citation Reports © Ranking: 2012: 12/34 (Virology); 21/70 (Infectious Diseases); 26/74 (Gastroenterology & Hepatology)

Online ISSN: 1365-2893


  1. 1 - 72
  1. Original Articles

    1. Role of CYP27B1+2838 promoter polymorphism in the treatment of chronic hepatitis B HBeAg negative with PEG-interferon

      L. Boglione, J. Cusato, A. De Nicolò, G. Cariti, G. Di Perri and A. D'Avolio

      Article first published online: 24 JUL 2014 | DOI: 10.1111/jvh.12288

  2. Letters to the Editor

  3. Original Articles

    1. Methylation of suppressor of cytokine signalling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure

      J.-J. Zhang, Y.-C. Fan, Z.-H. Zhang, J. Han, L.-Y. Wang, T. Li, F. Zhang, Y.-P. Yin, L.-H. Hu, Y. Yang, F.-K. Sun and K. Wang

      Article first published online: 21 JUL 2014 | DOI: 10.1111/jvh.12286

  4. Meta-Analysis

  5. Original Articles

    1. Hepatocellular carcinoma risk in HBeAg-negative chronic hepatitis B patients with or without cirrhosis treated with entecavir: HepNet.Greece cohort

      G. V. Papatheodoridis, S. Manolakopoulos, G. Touloumi, G. Nikolopoulou, M. Raptopoulou-Gigi, C. Gogos, I. Vafiadis-Zouboulis, D. Karamanolis, A. Chouta, A. Ilias, C. Drakoulis, K. Mimidis, I. Ketikoglou, E. Manesis, M. Mela, G. Hatzis, G. N. Dalekos and for the HepNet.Greece Study Group

      Article first published online: 15 JUL 2014 | DOI: 10.1111/jvh.12283

  6. Reviews

    1. Hepatitis A virus in the Middle East and North Africa region: a new challenge

      N. M. Melhem, R. Talhouk, H. Rachidi and S. Ramia

      Article first published online: 14 JUL 2014 | DOI: 10.1111/jvh.12282

  7. Original Articles

    1. Interferon–ribavirin therapy induces serum antibodies determining ‘rods and rings’ pattern in hepatitis C patients

      Cristina Novembrino, Alessio Aghemo, Chiara Ferraris Fusarini, Rita Maiavacca, Caterina Matinato, Giovanna Lunghi, Erminio Torresani, Mariangela Ronchi, Maria Cristina Garlaschi, Miriam Ramondetta and Massimo Colombo

      Article first published online: 14 JUL 2014 | DOI: 10.1111/jvh.12281

    2. Management of treatment-naïve chronic hepatitis C genotype 1 patients: a cost-effectiveness analysis of treatment options

      P. A. Cortesi, A. Ciaccio, M. Rota, J. K. Lim, S. De Salvia, S. Okolicsanyi, M. Vinci, L. S. Belli, L. G. Mantovani and M. Strazzabosco

      Article first published online: 10 JUL 2014 | DOI: 10.1111/jvh.12278

    3. Peginterferon-alfa mono-therapy in the treatment of acute hepatitis C in HIV-infection

      C. Boesecke, S. van Assen, H.-J. Stellbrink, A. Baumgarten, P. Ingiliz, C. P. Strassburg, C. Schwarze-Zander, J.-C. Wasmuth, A. I. M. Hoepelman, J. K. Rockstroh and J. E. Arends

      Article first published online: 9 JUL 2014 | DOI: 10.1111/jvh.12272

    4. HBV/HDV co-infection in the Western Brazilian Amazonia: an intriguing mutation among HDV genotype 3 carriers

      A. Kay, E. Melo da Silva, H. Pedreira, S. Negreiros, C. Lobato, W. Braga, R. Muwonge, P. Dény, M. Reis, F. Zoulim, C. Trepo, A. D´Oliveira Jr, J. M. Salcedo, M. I. Schinoni and R. Parana

      Article first published online: 9 JUL 2014 | DOI: 10.1111/jvh.12267

    5. Association between chronic hepatitis C virus infection and low muscle mass in US adults

      C. Gowda, C. Compher, V. K. Amorosa and V. Lo Re III

      Article first published online: 2 JUL 2014 | DOI: 10.1111/jvh.12273

    6. CUFA algorithm: assessment of liver fibrosis using routine laboratory data

      H. Shehab, I. Elattar, T. Elbaz, M. Mohey and G. Esmat

      Article first published online: 2 JUL 2014 | DOI: 10.1111/jvh.12270

    7. Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1

      K. Kosaka, M. Imamura, C. N. Hayes, H. Abe, N. Hiraga, S. Yoshimi, E. Murakami, T. Kawaoka, M. Tsuge, H. Aikata, D. Miki, H. Ochi, H. Matsui, A. Kanai, T. Inaba and K. Chayama

      Article first published online: 19 JUN 2014 | DOI: 10.1111/jvh.12271

  8. Letters to the Editor

    1. Telaprevir raises the plasma/whole blood ribavirin ratio: trying to come full circle on a dangerous relationship

      P. Menna, P. Gallo, U. Vespasiani Gentilucci, E. Salvatorelli, G. Galati, G. Minotti and A. Picardi

      Article first published online: 16 JUN 2014 | DOI: 10.1111/jvh.12264

  9. Original Articles

    1. Ribavirin dose reduction during telaprevir/ribavirin/peg-interferon therapy overcomes the effect of the ITPA gene polymorphism

      S. Akamatsu, C. N. Hayes, M. Tsuge, E. Murakami, N. Hiraga, H. Abe, D. Miki, M. Imamura, H. Ochi, K. Chayama and Hiroshima Liver Study Group

      Article first published online: 16 JUN 2014 | DOI: 10.1111/jvh.12275

    2. You have full text access to this OnlineOpen article
  10. Short Communications

    1. Canine hepacivirus and idiopathic hepatitis in dogs from a Dutch cohort

      L. J. W. van der Laan, P. E. de Ruiter, I. M. van Gils, H. Fieten, B. Spee, Q. Pan, J. Rothuizen and L. C. Penning

      Article first published online: 5 JUN 2014 | DOI: 10.1111/jvh.12268

  11. Original Articles

    1. Decline in intrahepatic cccDNA and increase in immune cell reactivity after 12 weeks of antiviral treatment were associated with HBeAg loss

      Q. Zheng, Y. Y. Zhu, J. Chen, Y. R. Liu, J. You, J. Dong, D. W. Zeng, L. Y. Gao, L. H. Chen and J. J. Jiang

      Article first published online: 1 JUN 2014 | DOI: 10.1111/jvh.12261

    2. Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA

      T. Kohno, M. Tsuge, E. Murakami, N. Hiraga, H. Abe, D. Miki, M. Imamura, H. Ochi, C. N. Hayes and K. Chayama

      Article first published online: 16 MAY 2014 | DOI: 10.1111/jvh.12240

    3. A simple and inexpensive point-of-care test for hepatitis B surface antigen detection: serological and molecular evaluation

      R. G. Gish, J. A. Gutierrez, N. Navarro-Cazarez, K. Giang, D. Adler, B. Tran, S. Locarnini, R. Hammond and S. Bowden

      Article first published online: 30 APR 2014 | DOI: 10.1111/jvh.12257

    4. Predictive value of serum actin-free Gc-globulin for complications and outcome in acute liver failure

      A. Bagchi, S. Kumar, P. C. Ray, B. C. Das, P. K. Gumma and P. Kar

      Article first published online: 28 APR 2014 | DOI: 10.1111/jvh.12259

    5. Seroprevalence of occult hepatitis B among Egyptian paediatric hepatitis C cancer patients

      H. E. Raouf, A. S. Yassin, S. A. Megahed, M. S. Ashour and T. M. Mansour

      Article first published online: 23 APR 2014 | DOI: 10.1111/jvh.12260

    6. Virological efficacy of combination therapy with corticosteroid and nucleoside analogue for severe acute exacerbation of chronic hepatitis B

      S. Yasui, K. Fujiwara, M. Nakamura, T. Miyamura, Y. Yonemitsu, R. Mikata, M. Arai, T. Kanda, F. Imazeki, S. Oda and O. Yokosuka

      Article first published online: 21 APR 2014 | DOI: 10.1111/jvh.12258

    7. Reasons for nonuse of antiviral treatment in patients with chronic hepatitis C infection and thrombocytopaenia: a retrospective chart review from five European countries

      M. Rizzetto, K. Grotzinger, D. Theodore, D. Demuth, W. L. Irving, M. Manns, A. Roughley and U. M. Forssen

      Article first published online: 2 APR 2014 | DOI: 10.1111/jvh.12256

    8. Absence of nonprimate hepacivirus-related genomes in blood donors seroreactive for hepatitis C virus displaying indeterminate blot patterns

      J. E. Levi, S. P. N. Cabral, A. Nishiya, S. Ferreira, C. M. Romano, M. B. C. Polite, R. A. A. Pereira, M. A. Mota and J. M. Kutner

      Article first published online: 2 APR 2014 | DOI: 10.1111/jvh.12252

    9. You have full text access to this OnlineOpen article
      Development and evaluation of a baseline-event-anticipation score for hepatitis delta

      B. Calle Serrano, A. Großhennig, M. Homs, B. Heidrich, A. Erhardt, K. Deterding, J. Jaroszewicz, B. Bremer, A. Koch, M. Cornberg, M. P. Manns, M. Buti and H. Wedemeyer

      Article first published online: 27 MAR 2014 | DOI: 10.1111/jvh.12251

    10. Maternal hepatitis B and hepatitis C infection and neonatal neurological outcomes

      J. L. Salemi, V. E. Whiteman, E. M. August, K. Chandler, A. K. Mbah and H. M. Salihu

      Article first published online: 26 MAR 2014 | DOI: 10.1111/jvh.12250

    11. Early predictors of antiviral treatment response in liver transplant recipients with recurrent hepatitis C genotype 1

      I. Campos-Varela, J. I. Esteban, M. Bes, M. Caralt, H. Allende, F. Rodríguez-Frías, M. T. Salcedo, S. Sauleda, R. Charco, J. Guardia, R. Esteban and L. Castells

      Article first published online: 12 MAR 2014 | DOI: 10.1111/jvh.12246

    12. SUMOylation of nonstructural 5A protein regulates hepatitis C virus replication

      H. S. Lee, Y. S. Lim, E. M. Park, S. H. Baek and S. B. Hwang

      Article first published online: 6 MAR 2014 | DOI: 10.1111/jvh.12241

    13. Boceprevir and telaprevir-based triple therapy for chronic hepatitis C: virological efficacy and impact on kidney function and model for end-stage liver disease score

      V. Virlogeux, P. Pradat, F. Bailly, G. Funingana, F. Gonçalves, M. Maynard, K. Hartig-Lavie, M. Amiri and F. Zoulim

      Article first published online: 25 FEB 2014 | DOI: 10.1111/jvh.12237

    14. Genotype I of hepatitis B virus was found in east Xishuangbanna, China and molecular dynamics of HBV/I

      T. Shen, X. M. Yan, H .X. Liu, B. X. Zhang, L. Li, J. P. Zhang, J. L. Wang and C. J. Xiao

      Article first published online: 18 FEB 2014 | DOI: 10.1111/jvh.12231

    15. Identification of a natural intergenotypic recombinant hepatitis delta virus genotype 1 and 2 in Vietnamese HBsAg-positive patients

      B. T. Sy, H. M. Nguyen, N. L. Toan, L. H. Song, H. V. Tong, C. Wolboldt, V. Q. Binh, P. G. Kremsner, T. P. Velavan and C.-T. Bock

      Article first published online: 18 FEB 2014 | DOI: 10.1111/jvh.12228

    16. You have full text access to this OnlineOpen article
    17. Acute and chronic immune biomarker changes during interferon/ribavirin treatment in HIV/HCV co-infected patients

      M. K. Jain, B. Adams-Huet, D. Terekhova, L. E. Kushner, R. Bedimo, X. Li and M. Holodniy

      Article first published online: 9 FEB 2014 | DOI: 10.1111/jvh.12226

    18. Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen

      M. Jiang, R. Broering, M. Trippler, L. Poggenpohl, M. Fiedler, G. Gerken, M. Lu and J. F. Schlaak

      Article first published online: 5 FEB 2014 | DOI: 10.1111/jvh.12216

    19. Gene expression analysis in serial liver fine needle aspirates

      S. Lejnine, M. J. Marton, I.-M. Wang, B. J. Howell, A. L. Webber, J. W. Maxwell, N. Shire, V. Malkov, J. Lunceford, M. Zeremski, A. Sun, M. Ruddy and A. H. Talal

      Article first published online: 29 JAN 2014 | DOI: 10.1111/jvh.12213

    20. The validity of serum markers for fibrosis staging in chronic hepatitis B and C

      J. Li, S. C. Gordon, L. B. Rupp, T. Zhang, J. A. Boscarino, V. Vijayadeva, M. A. Schmidt, M. Lu and for the Chronic Hepatitis Cohort Study (CHeCS) Investigators

      Article first published online: 29 JAN 2014 | DOI: 10.1111/jvh.12224

    21. Loss of intrahepatic HBsAg expression predicts sustained response to peginterferon and is reflected by pronounced serum HBsAg decline

      P. Arends, V. Rijckborst, P. E. Zondervan, E. Buster, Y. Cakaloglu, P. Ferenci, F. Tabak, U. S. Akarca, K. Simon, M. J. Sonneveld, B. E. Hansen and H. L. A. Janssen

      Article first published online: 20 JAN 2014 | DOI: 10.1111/jvh.12218

    22. Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy

      M. Lee, S. Oh, H. J. Lee, T.-S. Yeum, J.-H. Lee, S. J. Yu, H. Y. Kim, J.-H. Yoon, H.-S. Lee and Y. J. Kim

      Article first published online: 18 DEC 2013 | DOI: 10.1111/jvh.12217

    23. Long-term entecavir therapy results in falls in serum hepatitis B surface antigen levels and seroclearance in nucleos(t)ide-naïve chronic hepatitis B patients

      T. Hara, F. Suzuki, Y. Kawamura, H. Sezaki, T. Hosaka, N. Akuta, M. Kobayashi, Y. Suzuki, S. Saitoh, Y. Arase, K. Ikeda, M. Kobayashi, S. Watahiki, R. Mineta and H. Kumada

      Article first published online: 16 DEC 2013 | DOI: 10.1111/jvh.12211

    24. Association of a microRNA-323b polymorphism with the persistence of hepatitis B virus infection by the enhancement of viral replication

      S. J. Yu, J.-W. Kim, J.-H. Lee, J.-H. Yoon, H.-S. Lee, J. Y. Cheong, S. W. Cho, H. D. Shin and Y. J. Kim

      Article first published online: 16 DEC 2013 | DOI: 10.1111/jvh.12215

    25. Predictors associated with treatment initiation and switch in a real-world chronic hepatitis B population from five European countries

      H. Leblebicioglu, V. Arama, X. Causse, P. Marcellin, R. Ozaras, B. Postawa-Klozinska, K. Simon, A. I. Suceveanu, M. Wiese, S. Zeuzem, I. Klauck, E. Morais, S. Bjork, B. Lescrauwaet, D. Kamar, J. P. Zarski and for The AI463-121 European Longitudinal Chronic Hepatitis B Study Group

      Article first published online: 15 DEC 2013 | DOI: 10.1111/jvh.12202

    26. Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations

      A. Ayres, L. Yuen, K. M. Jackson, S. Manoharan, A. Glass, M. Maley, W. Yoo, S. P. Hong, S.-O. Kim, F. Luciani, D. S. Bowden, J. Bayliss, M. T. Levy and S. A. Locarnini

      Article first published online: 11 DEC 2013 | DOI: 10.1111/jvh.12212

    27. Treatment of severe, nonfulminant acute hepatitis B with lamivudine vs placebo: a prospective randomized double-blinded multicentre trial

      J. Wiegand, H. Wedemeyer, A. Franke, S. Rößler, S. Zeuzem, G. Teuber, M. Wächtler, U. Römmele, B. Ruf, U. Spengler, C. Trautwein, C. T. Bock, G. M. Fiedler, J. Thiery, M. P. Manns, O. Brosteanu, H. L. Tillmann and for the German Hep-Net Acute Hepatitis B (GAHB) Study Group

      Article first published online: 11 DEC 2013 | DOI: 10.1111/jvh.12210

    28. Maternal ABO and rhesus blood group phenotypes and hepatitis B surface antigen carriage

      T. T. Lao, D. S. Sahota, M.-K. Chung, T. K. W. Cheung, Y. K. Y. Cheng and T. Y. Leung

      Article first published online: 10 DEC 2013 | DOI: 10.1111/jvh.12219

    29. Age and gender differences in the relationship between hepatitis C infection and all stages of Chronic kidney disease

      W.-C. Li, Y.-Y. Lee, I.-C. Chen, S.-H. Wang, C.-T. Hsiao and S.-S. Loke

      Article first published online: 5 DEC 2013 | DOI: 10.1111/jvh.12199

    30. Hepatitis C virus core antigen testing in liver and kidney transplant recipients

      B. Heidrich, S. Pischke, F. A. Helfritz, I. Mederacke, J. Kirschner, J. Schneider, R. Raupach, E. Jäckel, H. Barg-Hock, F. Lehner, J. Klempnauer, T. von Hahn, M. Cornberg, M. P. Manns, S. Ciesek and H. Wedemeyer

      Article first published online: 19 NOV 2013 | DOI: 10.1111/jvh.12204

    31. Hepatitis B virus-specific T-cell responses during IFN administration in a small cohort of chronic hepatitis B patients under nucleos(t)ide analogue treatment

      M. F. Sprinzl, C. Russo, J. Kittner, S. Allgayer, A. Grambihler, B. Bartsch, A. Weinmann, P. R. Galle, M. Schuchmann, U. Protzer and T. Bauer

      Article first published online: 19 NOV 2013 | DOI: 10.1111/jvh.12189

    32. Cirrhosis but not neutropenia is associated with the development of infection in patients with chronic hepatitis C undergoing treatment with pegylated interferon-alpha and ribavirin

      A. Striki, S. Manolakopoulos, M. Deutsch, M. Mela, M. Kalafateli, M. Schini, O. Anagnostou, C. Triantos, I. Andreadis, I. Ketikoglou, G. Papatheodoridis and D. Pectasides

      Article first published online: 13 NOV 2013 | DOI: 10.1111/jvh.12197

    33. Hepatitis B: global scientific development from a critical point of view

      S. Schmidt, M. Bundschuh, C. Scutaru, D. Klingelhoefer, D. A. Groneberg and A. Gerber

      Article first published online: 10 NOV 2013 | DOI: 10.1111/jvh.12205

    34. Differences in hepatitis C virus prevalence and clearance by mode of acquisition among men who have sex with men

      E. C. Seaberg, M. D. Witt, L. P. Jacobson, R. Detels, C. R. Rinaldo, S. Young, J. P. Phair and C. L. Thio

      Article first published online: 7 NOV 2013 | DOI: 10.1111/jvh.12198

    35. Watchful waiting: role of disease progression on uncertainty and depressive symptoms in patients with chronic Hepatitis C

      J. P. Colagreco, D. E. Bailey, J. J. Fitzpatrick, C. M. Musil, N. H. Afdhal and M. Lai

      Article first published online: 7 NOV 2013 | DOI: 10.1111/jvh.12207

    36. Hepatitis B virus x protein induces autophagy via activating death-associated protein kinase

      H.-T Zhang, G. G. Chen, B.-G. Hu, Z.-Y. Zhang, J.-P Yun, M.-L. He and P. B. S. Lai

      Article first published online: 4 NOV 2013 | DOI: 10.1111/jvh.12191

    37. The impact of smoking on incident type 2 diabetes in a cohort with hepatitis B but not hepatitis C infection

      C.-S. Wang, T.-T. Chang, W.-J. Yao, S.-T. Wang and P. Chou

      Article first published online: 31 AUG 2010 | DOI: 10.1111/j.1365-2893.2010.01337.x


    1. Evaluation of initial virological response to adefovir and development of adefovir-resistant mutations in patients with chronic hepatitis B

      A. Gallego, J. Sheldon, J. García-Samaniego, N. Margall, M. Romero, P. Hornillos, V. Soriano and J. Enríquez

      Article first published online: 22 JAN 2008 | DOI: 10.1111/j.1365-2893.2007.00966.x

    2. MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma

      L. Segat, A. Fabris, L. Padovan, M. Milanese, D. Pirulli, F. Lupo, M. Salizzoni, A. Amoroso and S. Crovella

      Article first published online: 22 JAN 2008 | DOI: 10.1111/j.1365-2893.2007.00965.x


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