Neuropathology and Applied Neurobiology

Molecular Pathology Across Neurological Disorders Virtual Issue

The BNS Summer School entitled ‘Molecular Pathology across Neurological Disorders’ will take place at the Royal Agricultural University, Cirencester July 5th-7th 2017. The programme, arranged by Professor Silvia Marino, features education in a broad range of state of the art techniques in neuropathology and highlights the contribution of molecular pathology to our understanding of neuro-oncology, developmental disorders and neurodegenerative diseases. This virtual issue of Neuropathology and Applied Neurobiology brings together a sample of papers highlighting the use of advanced techniques to further our understanding neurological diseases.

The identification of raft-derived tau-associated vesicles that are incorporated into immature tangles and paired helical filaments.
Nishikawa T, Takahashi T, Nakamori M, Hosomi N, Maruyama H, Miyazaki Y, Izumi Y, Matsumoto M.

Free of acrylamide sodium dodecyl sulphate (SDS)-based tissue clearing (FASTClear): a novel protocol of tissue clearing for three-dimensional visualization of human brain tissues.
Liu AKL, Lai HM, Chang RC, Gentleman SM.

Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions.
Liu AK, Hurry ME, Ng OT, DeFelice J, Lai HM, Pearce RK, Wong GT, Chang RC, Gentleman SM.

Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease.
Chrysostomou A, Grady JP, Laude A, Taylor RW, Turnbull DM, Lax NZ.

Myopathology in the times of modern genetics.
Schuelke M, Øien NC, Oldfors A.

Myopathology in times of modern imaging.
Jungbluth H.

Review: Tau in biofluids - relation to pathology, imaging and clinical features.
Zetterberg H.

K27M mutation in H3F3A in ganglioglioma grade I with spontaneous malignant transformation extends the histopathological spectrum of the histone H3 oncogenic pathway.
Joyon N, Tauziède-Espariat A, Alentorn A, Giry M, Castel D, Capelle L, Zanello M, Varlet P, Bielle F.

Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease.
Lashley T, Gami P, Valizadeh N, Li A, Revesz T, Balazs R.

Review: Induced pluripotent stem cell models of frontotemporal dementia.
Preza E, Hardy J, Warner T, Wray S.