Addiction Biology

Cover image for Vol. 20 Issue 1

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Rainer Spanagel, Editor for North America: Markus Heilig

Impact Factor: 5.929

ISI Journal Citation Reports © Ranking: 2013: 1/18 (Substance Abuse); 37/291 (Biochemistry & Molecular Biology)

Online ISSN: 1369-1600

Associated Title(s): Addiction


  1. 1 - 100
  2. 101 - 102
  1. Original Articles

    1. Adenosine 2A receptors modulate reward behaviours for methamphetamine

      Rose Chesworth, Robyn M. Brown, Jee Hyun Kim, Catherine Ledent and Andrew J. Lawrence

      Article first published online: 22 JAN 2015 | DOI: 10.1111/adb.12225

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      Methamphetamine (METH) conditioned place preference was absent in adenosine A2A KO mice compared to wildtype littermates (WT). Intravenous self-administration of METH was intact in A2A KO mice; however, the motivation to self-administer was reduced in A2A KO mice compared to WT. Sucrose self-administration was also reduced in A2A KO mice, but only at higher schedules of reinforcement. These data suggest A2A signalling is critically required to integrate rewarding and motivational strength of drug and natural rewards.

  2. Invited Reviews

    1. Common single nucleotide variants underlying drug addiction: more than a decade of research

      Kora-Mareen Bühler, Elena Giné, Victor Echeverry-Alzate, Javier Calleja-Conde, Fernando Rodriguez de Fonseca and Jose Antonio López-Moreno

      Article first published online: 21 JAN 2015 | DOI: 10.1111/adb.12204

  3. Original Articles

    1. Effects of cognitive bias modification training on neural signatures of alcohol approach tendencies in male alcohol-dependent patients

      Corinde E. Wiers, Vera U. Ludwig, Thomas E. Gladwin, Soyoung Q. Park, Andreas Heinz, Reinout W. Wiers, Mike Rinck, Johannes Lindenmeyer, Henrik Walter and Felix Bermpohl

      Article first published online: 13 JAN 2015 | DOI: 10.1111/adb.12221

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      To investigate neural effects of Cognitive Bias Modification (CBM), 26 male alcohol-dependent patients performed either 3 weeks of CBM (N=13; 90% alcohol push) or placebo training (N=13; 50% alcohol push). After training, patients in the CBM group showed stronger reductions in medial prefrontal cortex activation while approaching versus avoiding alcohol cues compared with the placebo group, which correlated with reductions in behavioral approach tendencies. Reductions in medial prefrontal cortex activation may be important for the clinical effectiveness of CBM.

    2. You have full text access to this OnlineOpen article
      Heritability of compulsive Internet use in adolescents

      Jacqueline M. Vink, Toos C. E. M. van Beijsterveldt, Charlotte Huppertz, Meike Bartels and Dorret I. Boomsma

      Article first published online: 13 JAN 2015 | DOI: 10.1111/adb.12218

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      A life without internet is almost impossible nowadays so it is important to explore the determinants of compulsive internet use (CIU). The time spent on specific internet activities differed between sexes: adolescent boys spent more time on gaming (especially if high CIU-score) while girls spent more time on social network sites. The heritability estimates for CIU were the same for boys and girls: 48%. The remaining variance was due to unique environmental factors. No contribution of shared (family) environment was observed.

    3. Persistent palatable food preference in rats with a history of limited and extended access to methamphetamine self-administration

      Daniele Caprioli, Tamara Zeric, Eric B. Thorndike and Marco Venniro

      Article first published online: 12 JAN 2015 | DOI: 10.1111/adb.12220

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      The majority of male rats given a choice between cocaine and palatable food prefer the non-drug reward. We used a discrete choice procedure to determine palatable food versus methamphetamine preference in rats with a history of methamphetamine self-administration. Independent of the daily drug access conditions and withdrawal period, the rats strongly preferred the palatable food over methamphetamine, even after a priming injections or a satiation manipulation. Escalated methamphetamine intake or the progressive-ratio responding for the drug did not predict preference.

  4. Reviews

  5. Original Articles

    1. Nicotine produces chronic behavioral sensitization with changes in accumbal neurotransmission and increased sensitivity to re-exposure

      Julia Morud, Louise Adermark, Marta Perez-Alcazar, Mia Ericson and Bo Söderpalm

      Article first published online: 8 JAN 2015 | DOI: 10.1111/adb.12219

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      Tobacco use is often associated with long-term addiction as well as high risk of relapse. This is suggestive of persistent neural adaptations. In order to investigate the long-term effects of nicotine exposure rats were treated for three weeks with nicotine, and the duration of behavioral and neurophysiological adaptations were evaluated seven months later. We found that drug-induced locomotion persisted seven months after drug exposure together with altered synaptic activity and in vitro response to quinpirole.

    2. Glutamatergic and neurometabolic alterations in chronic cocaine users measured with 1H-magnetic resonance spectroscopy

      Lea M. Hulka, Milan Scheidegger, Matthias Vonmoos, Katrin H. Preller, Markus R. Baumgartner, Marcus Herdener, Erich Seifritz, Anke Henning and Boris B. Quednow

      Article first published online: 30 DEC 2014 | DOI: 10.1111/adb.12217

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      Glutamate and glutamine levels in the pgACC and the rDLPFC measured with 1H-MRS did not differ between cocaine users and controls but higher weekly cocaine use and cocaine hair concentrations were associated with lower glutamine/creatine in the pgACC. Cocaine users exhibited higher glucose/creatine than controls in the pgACC and higher choline/creatine in the pgACC and rDLPFC. Thus, cocaine use is associated with altered glucose metabolism and membrane turnover and appears to decrease glutamine levels indicating changes in glutamate cycling.

    3. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol

      Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin and Etienne Quertemont

      Article first published online: 24 DEC 2014 | DOI: 10.1111/adb.12216

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      The present study tested whether in vivo ethanol locomotor sensitization correlates with changes in either basal or ethanol-evoked firing rates of dopamine neurons in vitro in mice. Higher spontaneous basal firing rates of dopamine neurons were observed in ethanol sensitized mice relative to control mice, but without correlations with the behavioral effects. Ethanol-evoked firing rates of dopamine neurons were of higher magnitude in ethanol sensitized mice. Furthermore, this sensitization of dopamine neuron activity was significantly correlated with ethanol behavioral sensitization.

    4. Regulation of dopaminergic markers expression in response to acute and chronic morphine and to morphine withdrawal

      Daniel García-Pérez, Cristina Núñez, M. Luisa Laorden and M. Victoria Milanés

      Article first published online: 17 DEC 2014 | DOI: 10.1111/adb.12209

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      Dopamine is thought to represent a teaching signal and has been implicated in the induction of addictive behaviours. Increased Nurr1 and/or Pitx3 levels during morphine dependence and in morphine-withdrawn rats were associated to an increase of DAT, VMAT2 and DRD2, indicating that morphine dependence and withdrawal induced consistent alterations of most of the dopaminergic markers. Thus, Nurr1 and Pitx3 regulation might be associated with controlling adaptation to morphine dependence-induced alterations of DA neurons activity in the mesolimbic pathway.

    5. Differential regulation of mGlu5R and ΜOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice

      Polymnia Georgiou, Panos Zanos, Mazdak Ehteramyan, Susanna Hourani, Ian Kitchen, Rafael Maldonado and Alexis Bailey

      Article first published online: 17 DEC 2014 | DOI: 10.1111/adb.12208

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      This study assessed the modulation of metabotropic glutamate receptor 5 (mGlu5R) and μ-opioid receptors (MOPr) in a mouse model of cue- and priming-induced reinstatement of cocaine-seeking. We showed that priming- but not cue-induced reinstatement upregulates mGlu5R and MOPr binding in the nucleus accumbens and basolateral amygdala respectively, whilst cue- but not priming-induced reinstatement downregulates MOPr binding in caudate putamen and nucleus accumbens. We provide direct evidence of reinstatement-induced receptor alterations that are likely to contribute to the neurobiology of relapse.

    6. Self-efficacy mediates the effects of topiramate and GRIK1 genotype on drinking

      Henry R. Kranzler, Stephen Armeli, Reagan Wetherill, Richard Feinn, Howard Tennen, Joel Gelernter, Jonathan Covault and Timothy Pond

      Article first published online: 15 DEC 2014 | DOI: 10.1111/adb.12207

    7. Linear pharmacokinetics of 3,4-methylenedioxypyrovalerone (MDPV) and its metabolites in the rat: relationship to pharmacodynamic effects

      Sebastien Anizan, Marta Concheiro, Kurt R. Lehner, Mohammad O. Bukhari, Masaki Suzuki, Kenner C. Rice, Michael H. Baumann and Marilyn A. Huestis

      Article first published online: 5 DEC 2014 | DOI: 10.1111/adb.12201

    8. Brain function during cognitive flexibility and white matter integrity in alcohol-dependent patients, problematic drinkers and healthy controls

      Jochem M. Jansen, Ruth J. van Holst, Wim van den Brink, Dick J. Veltman, Matthan W. A. Caan and Anna E. Goudriaan

      Article first published online: 5 DEC 2014 | DOI: 10.1111/adb.12199

    9. You have full text access to this OnlineOpen article
      The role of ghrelin signalling for sexual behaviour in male mice

      Emil Egecioglu, Luna Prieto-Garcia, Erik Studer, Lars Westberg and Elisabet Jerlhag

      Article first published online: 4 DEC 2014 | DOI: 10.1111/adb.12202

  6. Reviews

    1. Recent updates on incubation of drug craving: a mini-review

      Xuan Li, Daniele Caprioli and Nathan J. Marchant

      Article first published online: 1 DEC 2014 | DOI: 10.1111/adb.12205

  7. Original Articles

    1. Reduced striatal dopamine transporter density associated with working memory deficits in opioid-dependent male subjects: a SPECT study

      Chih-Sung Liang, Pei-Shen Ho, Che-Hung Yen, Yi-Wei Yeh, Shin-Chang Kuo, Chang-Chih Huang, Chun-Yen Chen, Mei-Chen Shih, Kuo-Hsing Ma and San-Yuan Huang

      Article first published online: 1 DEC 2014 | DOI: 10.1111/adb.12203

    2. Enkephalin is essential for the molecular and behavioral expression of cocaine sensitization

      Bethania Mongi-Bragato, Emiliano Zamponi, Constanza García-Keller, María Amparo Assis, Miriam B. Virgolini, Daniel H. Mascó, Andreas Zimmer and Liliana M. Cancela

      Article first published online: 27 NOV 2014 | DOI: 10.1111/adb.12200

    3. Adolescent pre-treatment with oxytocin protects against adult methamphetamine-seeking behavior in female rats

      Callum Hicks, Jennifer L. Cornish, Sarah J. Baracz, Anastasia Suraev and Iain S. McGregor

      Article first published online: 17 NOV 2014 | DOI: 10.1111/adb.12197

    4. Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine-seeking behaviour in rats

      Sarah J. Baracz, Nicholas A. Everett, Iain S. McGregor and Jennifer L. Cornish

      Article first published online: 16 NOV 2014 | DOI: 10.1111/adb.12198

    5. Methamphetamine induces a rapid increase of intracellular Ca++ levels in neurons overexpressing GCaMP5

      Seong-Jin Yu, Kou-Jen Wu, Eun K. Bae, Man-Jung Hsu, Christopher T. Richie, Brandon K. Harvey and Yun Wang

      Article first published online: 6 NOV 2014 | DOI: 10.1111/adb.12193

    6. Biobehavioral mechanisms of topiramate's effects on alcohol use: an investigation pairing laboratory and ecological momentary assessments

      Robert Miranda Jr., James MacKillop, Hayley Treloar, Alexander Blanchard, Jennifer W. Tidey, Robert M. Swift, Thomas Chun, Damaris J. Rohsenow and Peter M. Monti

      Article first published online: 29 OCT 2014 | DOI: 10.1111/adb.12192

    7. Dissociation of μ-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL/6J mice

      Lara S. Hwa, Akiko Shimamoto, Tala Kayyali, Kevin J. Norman, Rita J. Valentino, Joseph F. DeBold and Klaus A. Miczek

      Article first published online: 28 SEP 2014 | DOI: 10.1111/adb.12189

    8. Abuse potential and adverse cognitive effects of mitragynine (kratom)

      Nurul H. M. Yusoff, Farah W. Suhaimi, Raja K. Vadivelu, Zurina Hassan, Anne Rümler, Andrea Rotter, Davide Amato, Hans C. Dringenberg, Sharif M. Mansor, Visweswaran Navaratnam and Christian P. Müller

      Article first published online: 28 SEP 2014 | DOI: 10.1111/adb.12185

    9. Social defeat in adolescent mice increases vulnerability to alcohol consumption

      Marta Rodriguez-Arias, Francisco Navarrete, Maria Carmen Blanco-Gandia, Maria Carmen Arenas, Adrián Bartoll-Andrés, Maria A. Aguilar, Gabriel Rubio, José Miñarro and Jorge Manzanares

      Article first published online: 14 SEP 2014 | DOI: 10.1111/adb.12184

    10. Predicting subsequent relapse by drug-related cue-induced brain activation in heroin addiction: an event-related functional magnetic resonance imaging study

      Qiang Li, Wei Li, Hanyue Wang, Yarong Wang, Yi Zhang, Jia Zhu, Ying Zheng, Dongsheng Zhang, Lina Wang, Yongbin Li, Xuejiao Yan, Haifeng Chang, Min Fan, Zhe Li, Jie Tian, Mark S. Gold, Wei Wang and Yijun Liu

      Article first published online: 11 SEP 2014 | DOI: 10.1111/adb.12182

    11. Molecular basis of reduced birth weight in smoking pregnant women: mitochondrial dysfunction and apoptosis

      Glòria Garrabou, Ana-Sandra Hernàndez, Marc Catalán García, Constanza Morén, Ester Tobías, Sarai Córdoba, Marta López, Francesc Figueras, Josep M. Grau and Francesc Cardellach

      Article first published online: 3 SEP 2014 | DOI: 10.1111/adb.12183

    12. Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging

      Mateusz Dudek, Usama Abo-Ramadan, Derik Hermann, Matthew Brown, Santiago Canals, Wolfgang H. Sommer and Petri Hyytiä

      Article first published online: 22 AUG 2014 | DOI: 10.1111/adb.12179

    13. Memantine reduces alcohol drinking but not relapse in alcohol-dependent rats

      Stéphanie Alaux-Cantin, Romain Buttolo, Hakim Houchi, Jérôme Jeanblanc and Mickaël Naassila

      Article first published online: 20 AUG 2014 | DOI: 10.1111/adb.12177

    14. Moderate alcohol exposure during early brain development increases stimulus-response habits in adulthood

      Matthew O. Parker, Alexandra M-D. Evans, Alistair J. Brock, Fraser J. Combe, Muy-Teck Teh and Caroline H. Brennan

      Article first published online: 19 AUG 2014 | DOI: 10.1111/adb.12176

    15. Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation

      Paola Devoto, Liana Fattore, Silvia Antinori, Pierluigi Saba, Roberto Frau, Walter Fratta and Gian Luigi Gessa

      Article first published online: 19 AUG 2014 | DOI: 10.1111/adb.12178

    16. Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens

      Meriem Gaval-Cruz, Richard B. Goertz, Daniel J. Puttick, Dawn E. Bowles, Rebecca C. Meyer, Randy A. Hall, Daijin Ko, Carlos A. Paladini and David Weinshenker

      Article first published online: 13 AUG 2014 | DOI: 10.1111/adb.12174

    17. Lower subcortical gray matter volume in both younger smokers and established smokers relative to non-smokers

      Colleen A. Hanlon, Max M. Owens, Jane E. Joseph, Xun Zhu, Mark S. George, Kathleen T Brady and Karen J. Hartwell

      Article first published online: 13 AUG 2014 | DOI: 10.1111/adb.12171

    18. High-dose alcohol intoxication differentially modulates cognitive subprocesses involved in response inhibition

      Ann-Kathrin Stock, Tom Schulz, Martin Lenhardt, Meinolf Blaszkewicz and Christian Beste

      Article first published online: 6 AUG 2014 | DOI: 10.1111/adb.12170

    19. Inflated reward value in early opiate withdrawal

      Kate M. Wassum, Venuz Y. Greenfield, Kay E. Linker, Nigel T. Maidment and Sean B. Ostlund

      Article first published online: 31 JUL 2014 | DOI: 10.1111/adb.12172

    20. Pharmacodynamic effects of oral oxymorphone: abuse liability, analgesic profile and direct physiologic effects in humans

      Shanna Babalonis, Michelle R. Lofwall, Paul A. Nuzzo and Sharon L. Walsh

      Article first published online: 31 JUL 2014 | DOI: 10.1111/adb.12173

    21. Involvement of μ- and δ-opioid receptor function in the rewarding effect of (±)-pentazocine

      Tomohisa Mori, Toshimasa Itoh, Kazumi Yoshizawa, Yuya Ise, Keisuke Mizuo, Tomoya Saeki, Sachiko Komiya, Daiki Masukawa, Masahiro Shibasaki and Tsutomu Suzuki

      Article first published online: 27 JUL 2014 | DOI: 10.1111/adb.12169

    22. Effect of yohimbine on reinstatement of operant responding in rats is dependent on cue contingency but not food reward history

      Yu-Wei Chen, Kimberly A. Fiscella, Samuel Z. Bacharach, Gianluigi Tanda, Yavin Shaham and Donna J. Calu

      Article first published online: 27 JUL 2014 | DOI: 10.1111/adb.12164

    23. Nicotine enhances modulation of food-cue reactivity by leptin and ghrelin in the ventromedial prefrontal cortex

      Nils B. Kroemer, Franziska Wuttig, Martin Bidlingmaier, Ulrich S. Zimmermann and Michael N. Smolka

      Article first published online: 24 JUL 2014 | DOI: 10.1111/adb.12167

    24. Abuse potential of intranasal buprenorphine versus buprenorphine/naloxone in buprenorphine-maintained heroin users

      Jermaine D. Jones, Maria A. Sullivan, Suzanne K. Vosburg, Jeanne M. Manubay, Shanthi Mogali, Verena Metz and Sandra D. Comer

      Article first published online: 24 JUL 2014 | DOI: 10.1111/adb.12163

    25. Subchronic administration of atomoxetine causes an enduring reduction in context-induced relapse to cocaine seeking without affecting impulsive decision making

      Nienke Broos, Rhianne Loonstra, Yvar van Mourik, Dustin Schetters, Anton N. M. Schoffelmeer, Tommy Pattij and Taco J. De Vries

      Article first published online: 23 JUL 2014 | DOI: 10.1111/adb.12168

    26. The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex

      Yvonne E. Ogbonmwan, Natale R. Sciolino, Jessica L. Groves-Chapman, Kimberly G. Freeman, Jason P. Schroeder, Gaylen L. Edwards, Philip V. Holmes and David Weinshenker

      Article first published online: 23 JUL 2014 | DOI: 10.1111/adb.12166

    27. The histone deacetylase inhibitor sodium butyrate decreases excessive ethanol intake in dependent animals

      Emmanuelle Simon-O'Brien, Stéphanie Alaux-Cantin, Vincent Warnault, Romain Buttolo, Mickaël Naassila and Catherine Vilpoux

      Article first published online: 8 JUL 2014 | DOI: 10.1111/adb.12161

    28. The endocannabinoid system is altered in the post-mortem prefrontal cortex of alcoholic subjects

      Amaia M. Erdozain, Marina Rubio, Elsa M. Valdizan, Angel Pazos, J Javier Meana, Javier Fernández-Ruiz, Stephen P. H. Alexander and Luis F. Callado

      Article first published online: 8 JUL 2014 | DOI: 10.1111/adb.12160

    29. Involvement of reactive oxygen species in cocaine-taking behaviors in rats

      Eun Young Jang, Yeon-Hee Ryu, Bong Hyo Lee, Su-Chan Chang, Mi Jin Yeo, Sang Hyun Kim, Ryan J. Folsom, Nathan D. Schilaty, Kwang Joong Kim, Chae Ha Yang, Scott C. Steffensen and Hee Young Kim

      Article first published online: 26 JUN 2014 | DOI: 10.1111/adb.12159

    30. Altered brain functional networks in heavy smokers

      Fuchun Lin, Guangyao Wu, Ling Zhu and Hao Lei

      Article first published online: 24 JUN 2014 | DOI: 10.1111/adb.12155

    31. MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats

      Giordano de Guglielmo, Rémi Martin-Fardon, Koji Teshima, Roberto Ciccocioppo and Friedbert Weiss

      Article first published online: 16 JUN 2014 | DOI: 10.1111/adb.12157

    32. Impaired contextual fear extinction and hippocampal synaptic plasticity in adult rats induced by prenatal morphine exposure

      Ji-Wei Tan, Ting-Ting Duan, Qi-Xin Zhou, Ze-Yang Ding, Liang Jing, Jun Cao, Li-Ping Wang, Rong-Rong Mao and Lin Xu

      Article first published online: 5 JUN 2014 | DOI: 10.1111/adb.12158

    33. No differences in ventral striatum responsivity between adolescents with a positive family history of alcoholism and controls

      Kathrin U. Müller, Gabriela Gan, Tobias Banaschewski, Gareth J. Barker, Arun L. W. Bokde, Christian Büchel, Patricia Conrod, Mira Fauth-Bühler, Herta Flor, Jürgen Gallinat, Hugh Garavan, Penny Gowland, Andreas Heinz, Bernd Ittermann, Claire Lawrence, Eva Loth, Karl Mann, Jean-Luc Martinot, Frauke Nees, Tomáš Paus, Zdenka Pausova, Marcella Rietschel, Andreas Ströhle, Maren Struve, Gunter Schumann, Michael N. Smolka and IMAGEN Consortium

      Article first published online: 5 JUN 2014 | DOI: 10.1111/adb.12136

    34. Plasma profile of pro-inflammatory cytokines and chemokines in cocaine users under outpatient treatment: influence of cocaine symptom severity and psychiatric co-morbidity

      Pedro Araos, María Pedraz, Antonia Serrano, Miguel Lucena, Vicente Barrios, Nuria García-Marchena, Rafael Campos-Cloute, Juan J. Ruiz, Pablo Romero, Juan Suárez, Elena Baixeras, Rafael de la Torre, Jorge Montesinos, Consuelo Guerri, Marta Rodríguez-Arias, José Miñarro, Roser Martínez-Riera, Marta Torrens, Julie A. Chowen, Jesús Argente, Barbara J. Mason, Francisco J. Pavón and Fernando Rodríguez de Fonseca

      Article first published online: 22 MAY 2014 | DOI: 10.1111/adb.12156

    35. Association of substance dependence phenotypes in the COGA sample

      Leah Wetherill, Arpana Agrawal, Manav Kapoor, Sarah Bertelsen, Laura J. Bierut, Andrew Brooks, Danielle Dick, Michie Hesselbrock, Victor Hesselbrock, Daniel L. Koller, Nhung Le, John I. Nurnberger Jr., Jessica E. Salvatore, Marc Schuckit, Jay A. Tischfield, Jen-Chyong Wang, Xiaoling Xuei, Howard J. Edenberg, Bernice Porjesz, Kathleen Bucholz, Alison M. Goate and Tatiana Foroud

      Article first published online: 16 MAY 2014 | DOI: 10.1111/adb.12153

    36. Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes

      Laura E. Kwako, Melanie L. Schwandt, Joanna R. Sells, Vijay A. Ramchandani, Daniel W. Hommer, David T. George, Rajita Sinha and Markus Heilig

      Article first published online: 7 MAY 2014 | DOI: 10.1111/adb.12150

    37. Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse

      Segev Barak, Jun Wang, Somayeh Ahmadiantehrani, Sami Ben Hamida, Adrian P. Kells, John Forsayeth, Krystof S. Bankiewicz and Dorit Ron

      Article first published online: 6 MAY 2014 | DOI: 10.1111/adb.12152

    38. Sleep changes in smokers before, during and 3 months after nicotine withdrawal

      Andreas Jaehne, Thomas Unbehaun, Bernd Feige, Stefan Cohrs, Andrea Rodenbeck and Dieter Riemann

      Article first published online: 4 MAY 2014 | DOI: 10.1111/adb.12151

    39. Neuropeptide S receptor gene variant and environment: contribution to alcohol use disorders and alcohol consumption

      Kariina Laas, Andreas Reif, Kirsti Akkermann, Evelyn Kiive, Katharina Domschke, Klaus-Peter Lesch, Toomas Veidebaum and Jaanus Harro

      Article first published online: 23 APR 2014 | DOI: 10.1111/adb.12149

    40. Cumulative gains enhance striatal response to reward opportunities in alcohol-dependent patients

      Jodi M. Gilman, Ashley R. Smith, James M. Bjork, Vijay A. Ramchandani, Reza Momenan and Daniel W. Hommer

      Article first published online: 23 APR 2014 | DOI: 10.1111/adb.12147

    41. Pathological gambling and alcohol dependence: neural disturbances in reward and loss avoidance processing

      Nina Romanczuk-Seiferth, Saskia Koehler, Caspar Dreesen, Torsten Wüstenberg and Andreas Heinz

      Article first published online: 22 APR 2014 | DOI: 10.1111/adb.12144

    42. Role of α4- and α6-containing nicotinic receptors in the acquisition and maintenance of nicotine self-administration

      Heather B. Madsen, Harcharan S. Koghar, Tine Pooters, Jim S. Massalas, John Drago and Andrew J. Lawrence

      Article first published online: 22 APR 2014 | DOI: 10.1111/adb.12148

    43. Cocaine use severity and cerebellar gray matter are associated with reversal learning deficits in cocaine-dependent individuals

      Laura Moreno-López, José C. Perales, Dana van Son, Natalia Albein-Urios, Carles Soriano-Mas, Jose M. Martinez-Gonzalez, Reinout W. Wiers and Antonio Verdejo-García

      Article first published online: 17 APR 2014 | DOI: 10.1111/adb.12143

    44. Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population

      Michael Way, Andrew McQuillin, Jit Saini, Kush Ruparelia, Gregory J. Lydall, Irene Guerrini, David Ball, Iain Smith, Giorgia Quadri, Allan D. Thomson, Katherine Kasiakogia-Worlley, Raquin Cherian, Priyanthi Gunwardena, Harish Rao, Girija Kottalgi, Shamir Patel, Audrey Hillman, Ewen Douglas, Sherhzad Y. Qureshi, Gerry Reynolds, Sameer Jauhar, Aideen O'Kane, Alex Dedman, Sally Sharp, Radhika Kandaswamy, Karim Dar, David Curtis, Marsha Y. Morgan and Hugh M. D. Gurling

      Article first published online: 16 APR 2014 | DOI: 10.1111/adb.12141

    45. Light alcohol intake during adolescence induces alcohol addiction in a neurodevelopmental model of schizophrenia

      Jérôme Jeanblanc, Kevin Balguerie, Fabien Coune, Rémi Legastelois, Virginie Jeanblanc and Mickaël Naassila

      Article first published online: 13 APR 2014 | DOI: 10.1111/adb.12146

    46. A role for kappa-, but not mu-opioid, receptor activation in acute food deprivation-induced reinstatement of heroin seeking in rats

      Firas Sedki, Karine Eigenmann, Jessica Gelinas, Nicholas Schouela, Shannon Courchesne and Uri Shalev

      Article first published online: 13 APR 2014 | DOI: 10.1111/adb.12133

    47. Orbitofrontal response to drug-related stimuli after heroin administration

      Marc Walter, Niklaus Denier, Hana Gerber, Otto Schmid, Christian Lanz, Rudolf Brenneisen, Anita Riecher-Rössler, Gerhard A. Wiesbeck, Klaus Scheffler, Erich Seifritz, Philip McGuire, Paolo Fusar-Poli and Stefan Borgwardt

      Article first published online: 11 APR 2014 | DOI: 10.1111/adb.12145

    48. Extinction of a cocaine-taking context that protects against drug-primed reinstatement is dependent on the metabotropic glutamate 5 receptor

      Jee Hyun Kim, Christina Perry, Sophia Luikinga, Isabel Zbukvic, Robyn M. Brown and Andrew J. Lawrence

      Article first published online: 9 APR 2014 | DOI: 10.1111/adb.12142

    49. Incubation of alcohol craving during abstinence in patients with alcohol dependence

      Peng Li, Ping Wu, Xue Xin, Yun-Li Fan, Gui-Bin Wang, Fan Wang, Meng-Ying Ma, Ming-Ming Xue, Yi-Xiao Luo, Fu-De Yang, Yan-Ping Bao, Jie Shi, Hong-Qiang Sun and Lin Lu

      Article first published online: 2 APR 2014 | DOI: 10.1111/adb.12140

    50. Chronic alcohol alters rewarded behaviors and striatal plasticity

      Lauren DePoy, Rachel Daut, Tara Wright, Marguerite Camp, Nicole Crowley, Bianca Noronha, David Lovinger and Andrew Holmes

      Article first published online: 26 MAR 2014 | DOI: 10.1111/adb.12131

    51. Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine

      Adeline Cathala, Céline Devroye, Marlène Maitre, Pier Vincenzo Piazza, Djoher Nora Abrous, Jean-Michel Revest and Umberto Spampinato

      Article first published online: 24 MAR 2014 | DOI: 10.1111/adb.12137

    52. Alpha-melanocyte stimulating hormone modulates ethanol self-administration in posterior ventral tegmental area through melanocortin-4 receptors

      Gajanan P. Shelkar, Atmaram D. Kale, Uday Singh, Praful S. Singru, Nishikant K. Subhedar and Dadasaheb M. Kokare

      Article first published online: 18 MAR 2014 | DOI: 10.1111/adb.12126

  8. Invited Reviews

  9. Original Articles

    1. Interaction between early life stress and alcohol dependence on neural stress reactivity

      Hongyu Yang, Jeffrey S. Spence, Richard W. Briggs, Uma Rao, Carol North, Michael D. Devous Sr., Hong Xiao and Bryon Adinoff

      Article first published online: 7 MAR 2014 | DOI: 10.1111/adb.12135

    2. Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats

      Eduardo Karahanian, Mario Rivera-Meza, Lutske Tampier, María Elena Quintanilla, Mario Herrera-Marschitz and Yedy Israel

      Article first published online: 26 FEB 2014 | DOI: 10.1111/adb.12130

    3. Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

      Kathryn J. Reissner, Cassandra D. Gipson, Phuong K. Tran, Lori A. Knackstedt, Michael D. Scofield and Peter W. Kalivas

      Article first published online: 25 FEB 2014 | DOI: 10.1111/adb.12127

    4. A critical role for the melanocortin 4 receptor in stress-induced relapse to nicotine seeking in rats

      Xiaoli Qi, Hidetaka Yamada, Lu W. Corrie, Yue Ji, Rayna M. Bauzo, Jon C. Alexander and Adrie W. Bruijnzeel

      Article first published online: 24 FEB 2014 | DOI: 10.1111/adb.12129

    5. Repeated stress exposure causes strain-dependent shifts in the behavioral economics of cocaine in rats

      Peter A. Groblewski, Chad Zietz, Ingo Willuhn, Paul E. M. Phillips and Charles Chavkin

      Article first published online: 15 FEB 2014 | DOI: 10.1111/adb.12123

    6. Right anterior insula connectivity is important for cue-induced craving in nicotine-dependent smokers

      Megan M. Moran-Santa Maria, Karen J. Hartwell, Colleen A. Hanlon, Melanie Canterberry, Todd Lematty, Max Owens, Kathleen T. Brady and Mark S. George

      Article first published online: 13 FEB 2014 | DOI: 10.1111/adb.12124

  10. Brief Reports

    1. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95

      Rachel A. Daut, Erica F. Busch, Jessica Ihne, Daniel Fisher, Masayoshi Mishina, Seth G. N. Grant, Marguerite Camp and Andrew Holmes

      Article first published online: 7 JAN 2014 | DOI: 10.1111/adb.12110

  11. Original Articles

    1. [18F]MK-9470 PET measurement of cannabinoid CB1 receptor availability in chronic cannabis users

      Jenny Ceccarini, Rebecca Kuepper, Dieter Kemels, Jim van Os, Cécile Henquet and Koen Van Laere

      Article first published online: 27 DEC 2013 | DOI: 10.1111/adb.12116

    2. Increased impulsivity in rats as a result of repeated cycles of alcohol intoxication and abstinence

      Cristina Irimia, Joost Wiskerke, Luis A. Natividad, Ilham Y. Polis, Taco J. de Vries, Tommy Pattij and Loren H. Parsons

      Article first published online: 17 DEC 2013 | DOI: 10.1111/adb.12119

    3. Emotional graphic cigarette warning labels reduce the electrophysiological brain response to smoking cues

      An-Li Wang, Dan Romer, Igor Elman, Bruce I. Turetsky, Ruben C. Gur and Daniel D. Langleben

      Article first published online: 15 DEC 2013 | DOI: 10.1111/adb.12117

    4. Chronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesia

      Paula E. Park, Joel E. Schlosburg, Leandro F. Vendruscolo, Gery Schulteis, Scott Edwards and George F. Koob

      Article first published online: 13 DEC 2013 | DOI: 10.1111/adb.12120

    5. Memory retrieval of smoking-related images induce greater insula activation as revealed by an fMRI-based delayed matching to sample task

      Amy C. Janes, Robert S. Ross, Stacey Farmer, Blaise B. Frederick, Lisa D. Nickerson, Scott E. Lukas and Chantal E. Stern

      Article first published online: 22 NOV 2013 | DOI: 10.1111/adb.12112


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