Cover image for Vol. 23 Issue 6

Edited By: Leo H. Bühler, MD

Impact Factor: 3.789

ISI Journal Citation Reports © Ranking: 2015: 7/25 (Transplantation); 27/124 (Medicine Research & Experimental)

Online ISSN: 1399-3089

Author Guidelines

Editorial Offices and Mailing Addresses:

Leo Bühler, MD

Xenotransplantation Editorial Office
Attention: Hillary Bixby, Managing Editor
350 Main Street
Malden, MA 02148
Tel: (+1) 952-405-6430
Fax: (+1) 781-338-8489
E-mail: xenadmin@wiley.com

Note to NIH Grantees - Pursuant to NIH mandate, Wiley-Blackwell will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance.  This accepted version will be made publicly available 12 months after publication.  For further information, see ww.wiley.com/go/nihmandate.

Copyright Transfer - If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions http://exchanges.wiley.com/authors/faqs---copyright-_301.html

Guidelines for cover submissions
If you would like to send suggestions for artwork related to your manuscript to be considered to appear on the cover of the journal, please follow these general guidelines.

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution Non-Commercial License OAA
Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://exchanges.wiley.com/authors/faqs---copyright-_301.html and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by certain funders [e.g.The Wellcome Trust and members of the Research Councils UK (RCUK) or the Austrian Sceince Fund (FWF)] you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.

For RCUK and Wellcome Trust authors click on the link below to preview the terms and conditions of this license:

Creative Commons Attribution License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://exchanges.wiley.com/authors/faqs---copyright-_301.html and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Onlnie Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at:

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

The journal to which you are submitting your manuscript employs a plagiarism detection system. By submitting your manuscript to this journal you accept that your manuscript may be screened for plagiarism against previously published works.

Types of papers published

Commentaries consist of brief reviews and opinions on a topic of interest in Xenotransplantation, and should generally not exceed 1,000 words. The editors welcome proposals for topics warranting a commentary.

Reviews are comprehensive but concise reviews of topics of interest. There is no absolute limit on length, but normally they should not exceed 3,000 words.

Rapid Communications are original papers of high originality and interest. If submission as a Rapid Communication is considered appropriate by the editors, these papers will be reviewed quickly and, if accepted, published in the next available issue. Non-acceptance as a Rapid Communication does not preclude publication as a regular Original Paper.

Original Papers are full-length reports of completed research relevant to xenotransplantation.

Brief Communications are brief or preliminary reports not exceeding 2500 words, including the abstract. They should be organized in the same way as full-length Original Papers, but the abstract should be no longer than 250 words. The number of references, tables and figures, should be compatible with the length of the paper.

Letters to the Editor that comment on any topic of relevance to xenotransplantation should not normally exceed 500 words and should have a very limited number of references with only a single table or figure, if necessary.

Book Reviews should normally not exceed 500 words.


The journal now accepts all submissions online.  Access to the online submission site is http://mc.manuscriptcentral.com/xen and full instructions can be found there. 

Please direct any questions or report any problems to the Editorial Office; contact details are above.

Authors submitting a paper do so on the understanding that the work has not been published before, is not being considered for publication elsewhere, and has been read and approved by all authors. Manuscripts, including tables and figures, should be sent in triplicate. The journal does not hold itself responsible for loss or damage to mailed manuscripts, or for statements made by contributors. (1) The paper should be submitted in English. (2) Type the manuscript (and legends, references, etc.) with wide margins and double-spaced. (3) Begin each manuscript component (title page, abstract, etc.) on a separate page.

Title page
Should contain (1) a concise informative title; (2) author(s)' names; (3) name of department(s)/institution(s) to which the work is attributed; (4) if the title exceeds 40 characters (letters and spaces), a running head of no more than 40 characters should be provided; (5) name, telephone number, fax number, e-mail and postal address of the author to whom correspondence, proofs, and requests for offprints should be directed.

Names department(s) and institution(s) of all authors. Credit for authorship should be based on: [1] substantial contributions to research design, or the acquisition, analysis or interpretation of data; [2] drafting the paper or revising it critically; [3] approval of the submitted and final versions. Authors should meet all three criteria.

Corresponding author
Name, address, email address, telephone and fax numbers. (Corresponding author should take responsibility for communicating with all other authors and getting their approval for the final version to be published. During online submission corresponding authors can nominate an individual, who may or may not be an author, to assist them with administration of the publication process.)

Author contributions
Recommendation: Include a short description of each authors’ contribution immediately before your references. (Examples of categories for authors’ contributions: Concept/design, Data analysis/interpretation, Drafting article, Critical revision of article, Approval of article, Statistics, Funding secured by, Data collection, Other.)

Abstract page
Should contain (1) the word Abstract followed by a summary of the article (2) 3-10 key words according to Index Medicus; (3) abbreviations used.

The Abstract should normally not be longer than 500 words and should be divided into 4 paragraphs, headed Background, Methods, Results, and Conclusions. Abstracts for Reviews and Brief Communications need not be so divided and should not exceed 250 words.

Present the background briefly, but do not review the subject extensively. Give only pertinent references. State the specific questions you want to answer.

Materials and methods
Identify methods, apparatus (manufacturer's name and address), and procedures in sufficient detail to allow other workers to reproduce the results. Provide references and only brief descriptions of methods that have been previously published.

Present results in logical sequence in tables and illustrations. In the text, explain, emphasize or summarize the most important observations. Units of measurement should be expressed in accordance with Systeme International d'Unités (SI Units).

Do not repeat in detail data given in the Results section. Emphasize the new and important aspects of the study. Relate the observations to other relevant studies. On the basis of your findings (and those of others), discuss possible implications/conclusions. When stating a new hypothesis, clearly label it as such.

Type each table on a separate sheet, with titles making them self-explanatory.

Figures should clarify the text. Their number should be kept to a minimum. Please submit clearly labeled tables and figures as high-quality TIFF, EPS, or JPEG images. Figure legends must be typed on a separate page at the end of the manuscript. Figures should be professionally drafted, and the halftones should exhibit high contrast. Details must be large enough to retain their clarity after reduction in size. After reduction, illustrations should preferably fill single-column width (81 mm) although in exceptional cases 2/3 page width (120 mm) or full-page width (168 mm) will be accepted. Any color illustrations must be paid for by the author. If there is colour artwork in your manuscript when it is accepted for publication, Wiley-Blackwell  requires you to complete and return a colour work agreement form before your paper can be published in colour. This form is also included with the eproofing documents sent to authors. If you do not return the form within 48 hours of receipt of the proof, we will assume that black and white reproduction is acceptable. This form is a  PDF* file.To read PDF files, you must have Acrobat Reader installed on your computer. If you do not have this program, this is available as a free download from the following web address: http://www.adobe.com/products/acrobat/readstep2.html.

If you are unable to download the form and would like a copy emailed to you, please contact the Editorial office at:

Xenotransplantation Editorial Office
Hillary Bixby, Managing Editor
350 Main Street
Malden, MA 02148
Tel: (+1) 952-405-6430
Fax: (+1) 781-338-8489
email: xenadmin@wiley.com

Once completed, please return the form to the Production Editor at the address below:
Ramakrishnan SG
Production Editor
Email: XEN@wiley.com

Abbreviations and symbols
Use only standard abbreviations. All units will be metric. In decimals, a decimal point (.), and not a comma, will be used. Avoid abbreviations in the title. The full term for which an abbreviation stands should precede its first use in the text unless it is a standard unit of measurement.


This journal now uses eLocators. For more information, please visit the Author Services eLocator page here.

All references should be numbered consecutively in order of appearance and should be as complete as possible. In text citations should cite references in consecutive order using Arabic superscript numerals. Sample references follow:

Journal article:
1. King VM, Armstrong DM, Apps R, Trott JR. Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 1998;390:537-551.

2. Voet D, Voet JG. Biochemistry. New York: John Wiley & Sons; 1990. 1223 p.

Please note that journal title abbreviations should conform to the practices of Chemical Abstracts.

For more information about AMA reference style - AMA Manual of Style

Proofs wil be sent via e-mail as an Acrobat PDF (portable document format) file.

Corresponding authors will automatically receive a free PDF offprint by e-mail. Additional offprints can be ordered on the offprint order form, which accompanies the proofs.

Early View

Xenotransplantation is covered by Wiley-Blackwell Publishing‟s Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Articles are therefore available as soon as they are ready, rather than having to wait for the next scheduled print issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors‟ final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so Early View articles cannot be cited in the traditional way. They are therefore given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before it is allocated to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article. (Back

Author Services

NEW: Online production tracking is now available for articles through Wiley-Blackwell’s Author Services.

Author Services enables authors to track their article - once it has been accepted – through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production so they do not need to contact the Production Editor to check on progress. Visit http://authorservices.wiley.com/bauthor/ for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

Author material archive policy

Please note that unless specifically requested, Wiley-Blackwell will dispose of all hardcopy or electronic material submitted two months after publication. If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible if you have not yet done so.


The Publisher and Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this journal, the views and opinions expressed do not necessarily reflect those of the Publisher and the Editors, neither does the publication of advertisements constitute any endorsement by the Publisher and Editors of the products advertised.