Development, Growth & Differentiation

Cover image for Vol. 57 Issue 7

Edited By: Harukazu Nakamura

Impact Factor: 2.42

ISI Journal Citation Reports © Ranking: 2014: 26/41 (Developmental Biology); 124/184 (Cell Biology)

Online ISSN: 1440-169X

Recently Published Issues

See all

Special Issues

See all issues

Recently Published Articles

  1. Development of the pancreas in medaka, Oryzias latipes, from embryo to adult

    Takayoshi Otsuka, Tatsuya Tsukahara and Hiroyuki Takeda

    Article first published online: 5 OCT 2015 | DOI: 10.1111/dgd.12237

    Thumbnail image of graphical abstract

    This article is the endocrine component of principal and secondary islets. Insulin-producing cells and Somatostatin-producing cells are located in the central of islets and glucagon-producing cells are in the periphery.

  2. Tangential cell migration during layer formation of chick optic tectum

    Yuji Watanabe and Hiroyuki Yaginuma

    Article first published online: 30 SEP 2015 | DOI: 10.1111/dgd.12238

    Thumbnail image of graphical abstract

    The laminated structure of the optic tectum is formed by radial and tangential cell migration during development. Studies of developing chick optic tectum have revealed two streams of tangential cell migration. We will review the process of the two types of tangential migrations, in order to elucidate their roles in the formation of the optic tectum layers.

  3. RAC1 regulate tumor necrosis factor-α-mediated impaired osteogenic differentiation of dental pulp stem cells (pages 497–506)

    Guijuan Feng, Qijie Shen, Min Lian, Zhifeng Gu, Jing Xing, Xiaohui Lu, Dan Huang, Liren Li, Shen Huang, Yi Wang, Jinlong Zhang, Jiahai Shi, Dongmei Zhang and Xingmei Feng

    Article first published online: 28 JUL 2015 | DOI: 10.1111/dgd.12233

    Thumbnail image of graphical abstract

    TNF-α could suppress the osteogenic differentiation of DPSCs via increasing the expression of RAC1, which could activate the Wnt/β-catenin signaling pathway and liberate β-catenin to translocate into the nucleus. Genetic silencing of RAC1 expression using siRNA restored osteogenic differentiation of DPSCs.

  4. Regulation of growth rate and developmental timing by Xenopus thyroid hormone receptor α

    Luan Wen and Yun-Bo Shi

    Article first published online: 28 JUL 2015 | DOI: 10.1111/dgd.12231

    Thumbnail image of graphical abstract

    Recent genetic studies by using TALEN have demonstrated an important role of thyroid hormone receptor TRα in regulating the timing of anuran metamorphosis. They have also revealed a novel function of the receptor in controlling premetamorphic tadpole growth rate.

  5. Identification of β integrin-like- and fibronectin-like proteins in the bivalve mollusk Mytilus trossulus (pages 515–528)

    Vyacheslav A. Dyachuk, Maria A. Maiorova and Nelly A. Odintsova

    Article first published online: 16 JUL 2015 | DOI: 10.1111/dgd.12234

    Thumbnail image of graphical abstract

    The main result of our study is the discovery of the fact that β integrin-like protein expression correlates with the development and differentiation of the digestive system in mollusk larvae. Despite the β integrin- and fibronectin-like proteins were expressed in different cell types of mussel larvae, we do not exclude the possibility of direct interaction between these two proteins during M. trossulus development or in adult tissues. These novel results should accelerate interest in studying the integrin/ligand variations and functions in non-model marine organisms.