Development, Growth & Differentiation

Cover image for Vol. 58 Issue 9

Edited By: Harukazu Nakamura

Impact Factor: 2.412

ISI Journal Citation Reports © Ranking: 2015: 20/41 (Developmental Biology); 128/187 (Cell Biology)

Online ISSN: 1440-169X

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  1. Roles and regulations of Hippo signaling during preimplantation mouse development

    Hiroshi Sasaki

    Version of Record online: 30 DEC 2016 | DOI: 10.1111/dgd.12335

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    Hippo signaling pathway plays major roles in regulation of cell fate specification in preimplantation embryos. I will summarize the roles and regulations of the Hippo signaling pathway during preimplantation development, and discuss how the embryos form the early blastocyst via self-organizing mechanisms.

  2. Mechanistic aspects of mammalian cell size control

    Kazuo Yamamoto and Tak W. Mak

    Version of Record online: 30 DEC 2016 | DOI: 10.1111/dgd.12334

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    We identified “Largen” as a cell size regulator in mammalian cell. With the findings on Largen, we discuss the possible contribution of mitochondria and protein biosynthesis to the control of mammalian cell size.

  3. Temporal dissociation of developmental events in the chick eye under low temperature conditions (pages 741–749)

    Hideaki Iida, Tiantian Yang, Sadao Yasugi and Yasuo Ishii

    Version of Record online: 6 DEC 2016 | DOI: 10.1111/dgd.12330

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    The chick eye develops through successive morphological changes that occur concordantly under normal circumstances. Lowering of incubation temperature to 29°C delays the onset of invagination, but not thickening, of the lens, resulting in abnormal protrusion of the eye.

  4. Nitric oxide synthase during early embryonic development in silkworm Bombyx mori: Gene expression, enzyme activity, and tissue distribution (pages 750–756)

    Ryo Kitta, Marina Kuwamoto, Yumi Yamahama, Keisuke Mase and Hiroshi Sawada

    Version of Record online: 29 NOV 2016 | DOI: 10.1111/dgd.12331

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    To elucidate the mechanism for embryonic diapause or breaking down diapause by HCl in Bombyx mori, we analyzed nitric oxide synthase (NOS) during the embryogenesis of B. mori. The gene expression, enzyme activity and tissue distribution of B. mori NOS (BmNOS) were examined in diapause, non-diapause, and HCl-treated diapause eggs. The results in these analyses suggested that BmNOS has an important role in the early embryonic development of the B. mori.

  5. Transcriptional and post-transcriptional regulation of histone variant H2A.Z during sea urchin development (pages 727–740)

    Mihai Hajdu, Jasmine Calle, Andrea Puno, Aminat Haruna and César Arenas-Mena

    Version of Record online: 29 NOV 2016 | DOI: 10.1111/dgd.12329

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    High levels of H2A.Z are required during early sea urchin development, but to a lesser extent in differentiated cells. H2A.Z regulation during embryogenesis is primarily transcriptional. Maximum expression of H2A.Z is strongly dependent on a cis-regulatory module that shows high chromatin accessibility and a functional Myb-related transcription factor binding site.