Development, Growth & Differentiation
© 2015 Japanese Society of Developmental Biologists
Edited By: Harukazu Nakamura
Impact Factor: 2.178
ISI Journal Citation Reports © Ranking: 2013: 29/41 (Developmental Biology); 134/185 (Cell Biology)
Online ISSN: 1440-169X
Read Special Issue free online, featuring key research and review articles on Genome Editing, edited by T. Yamamoto and H. Nakamura.
Recently Published Articles
- Gene expression kinetics in individual plasmodial cells reveal alternative programs of differential regulation during commitment and differentiation
Viktoria Rätzel and Wolfgang Marwan
Article first published online: 26 MAY 2015 | DOI: 10.1111/dgd.12220
By repeatedly taking samples of the same plasmodial cell at successive time points after the induction to sporulation we show that individual cells take different trajectories leading to cell fate decision and differentiation. Pair-wise correlated gene expression kinetics revealed qualitatively different patterns of co-regulation, indicating that alternative programs of differential regulation are operational in individual plasmodial cells. The results support the concept of a Waddington-type quasipotential landscape for the regulatory control of cell differentiation and the impact of mutations on the topology of the landscape.
- Early development of circadian rhythmicity in the suprachiamatic nuclei and pineal gland of teleost, flounder (Paralichthys olivaeus), embryos
Makoto Mogi, Susumu Uji, Hayato Yokoi and Tohru Suzuki
Article first published online: 26 MAY 2015 | DOI: 10.1111/dgd.12222
We report the development of circadian rhythmicity in the SCN and PG. per2 expression rhythmicity in flounder SCN is regulated by a molecular clock. LL and DD conditions deeply affect the development of circadian rhythmicity in the SCN and PG.
- SP1 promotes the odontoblastic differentiation of dental papilla cells
Jie Zhang, Heng Lin, Huan Liu, Lu Zhang, Guohua Yuan and Zhi Chen
Article first published online: 24 MAY 2015 | DOI: 10.1111/dgd.12221
We observed that the expression of SP1 progressively upregulated during the odontoblastic differentiation both in vivo and in vitro. Overexpression and knock-down of SP1 forced and suppressed the odontoblastic differentiation of the mDPC6T cells, respectively. In conclusion, SP1 promotes the odontoblastic differentiation of dental papilla cells.
- Mechanisms of cell height changes that mediate epithelial invagination (pages 313–323)
Takefumi Kondo and Shigeo Hayashi
Article first published online: 19 MAY 2015 | DOI: 10.1111/dgd.12224
Invagination is the core process of the three-dimensional morphogenesis of epithelial organs driven by shape change of each epithelial cells. Recent progress in this field is reviewed here with special emphasis on cell height control.
- Asymmetrical allocation of JAK1 mRNA during spermatogonial stem cell division in Xenopus laevis
Keiichiro Hyakutake, Toshihiro Kawasaki, JiDong Zhang, Hiroshi Kubota, Sin-Ichi Abe and Kazufumi Takamune
Article first published online: 19 MAY 2015 | DOI: 10.1111/dgd.12219
Xenopus spermatogonial stem cells (SSCs) at telophase. Primary spermatogonium destined to differentiate and SSC are thought to arise from areas in which JAK1 mRNA (blue signals in the middle and right column) is present (arrowheads) and absent (double arrowheads), respectively.