Psychiatry and Clinical Neurosciences

Cover image for Vol. 70 Issue 2

Edited By: Shigenobu Kanba and Tadafumi Kato

Impact Factor: 1.634

ISI Journal Citation Reports © Ranking: 2014: 91/140 (Psychiatry); 135/192 (Clinical Neurology); 197/252 (Neurosciences)

Online ISSN: 1440-1819

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Magnetoencephalography in the study of children with autism spectrum disorder
Mitsuru Kikuchi, Yuko Yoshimura, et al.
Volume 70 Issue 2 - February 2016

Promising evidence and remaining issues regarding the clinical application of oxytocin in autism spectrum disorders
Hidenori Yamasue
Volume 70 Issue 2 - February 2016

Multidimensional anatomy of ‘modern type depression’ in Japan: A proposal for a different diagnostic approach to depression beyond the DSM-5
Takahiro A. Kato, Ryota Hashimoto, et al.
Volume 70 Issue 1 - January 2016

Tobacco smoking: From ‘glamour’ to ‘stigma’. A comprehensive review
João Mauricio Castaldelli-Maia, Antonio Ventriglio, et al.
Volume 70 Issue 1 - January 2016

Generalized social anxiety disorder: A still-neglected anxiety disorder 3 decades since Liebowitz's review
Toshihiko Nagata, Futoshi Suzuki, et al.
Volume 69 Issue 12 - December 2015

Schizophrenia in 2020: Trends in diagnosis and therapy
Wolfgang Gaebel and Jürgen Zielasek
Volume 69 Issue 11 - November 2015

Practical pharmacotherapy for acute schizophrenia patients
Kotaro Hatta
Volume 69 Issue 11 - November 2015

Biochemical markers subtyping major depressive disorder
Hiroshi Kunugi, Hiroaki Hori, et al.
Volume 69 Issue 10 - October 2015

Statistical aspects of psychiatric inpatient care in Japan: Based on a comprehensive nationwide survey of psychiatric hospitals conducted from 1996 to 2012
Hisateru Tachimori, Tadashi Takeshima, et al.
Volume 69 Issue 9 - September 2015

Glia-related genes and their contribution to schizophrenia
Chenyao Wang, Branko Aleksic, et al.
Volume 69 Issue 8 - August 2015



Folia awards were established with aims to pursue the development of psychiatric research. One outstanding article per year is selected. Click on the title links to read these awarded articles for FREE

Unusual developmental pattern of brain lateralization in young boys with autism spectrum disorder: Power analysis with child-sized magnetoencephalography
Hirotoshi Hiraishi et al.
Volume 69 Issue 3 - March 2015

Effects of maternal depressive symptomatology during pregnancy and the postpartum period on infant–mother attachment
Harue Ohoka et al.
Volume 68 Issue 8 - August 2014

To access previously awarded articles, click here

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Increased Impact Factor 1.634 !
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EigenFactor 0.00399 (ranking 67/140 in Psychiatry)
5-year Impact Factor 2.193


Focusing on Mental Health (September 2015)

Cutting Edge of Anxiety and Obsessive Compulsive Disorder Research (July 2015)

Targets in Schizophrenia (May 2015)

Recent Findings of Neurodevelopmental Disorders in Japan (March 2015)

Conquering depression (January 2015)Free Online

Featured Articles - Free Online Access


Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression
Mikko Joensuu, Pasi Ahola, et al.
Volume 70 Issue 1 - January 2015

Clinical impact of 11C-Pittsburgh compound-B positron emission tomography carried out in addition to magnetic resonance imaging and single-photon emission computed tomography on the diagnosis of Alzheimer's disease in patients with dementia and mild cognitive impairment
Yoshie Omachi, Kimiteru Ito, et al.
Volume 69 Issue 12 - December 2015
This study investigated a degree of consistency in clinical and research diagnostic criteria of Alzheimer's disease, and the influences of PiB PET on such degree. The evaluation was performed under the present circumstances in Japan, that MRI is used for structural imaging and cerebral blood flow SPECT is used for functional imaging.

Longitudinal association between habitual physical activity and depressive symptoms in older people
Yuko Yoshida, Hajime Iwasa, et al.
Volume 69 Issue 11 - November 2015
This is a cohort study investigating the relationship between physical activity and depression symptoms among 950 community-dwelling older people. A state of physical activity and depression of the subjects during a 2-year period from 2002 to 2003 was examined, and 270 subjects who had depression symptoms in 2003 were excluded. The state of depression in 2006 in the remaining 680 subjects was examined, using the Geriatric Depression Scale. The results showed significantly lower rates of depression among subjects who had continued physical activities in 2002 and 2003, compared to the subjects who had not. With regards to the correlation between physical activity and depression, it was difficult to confirm the causality between these two parameters. However, this cohort study demonstrated very interesting results suggesting that physical activity may prevent depression.

Evaluation of resting state gamma power as a response marker in schizophrenia
Sayantanava Mitra, S. Haque Nizamie, et al.
Volume 69 Issue 10 - October 2015

Comparison of treatment selections by Japanese and US psychiatrists for major depressive disorder: A case vignette study
Atsuo Nakagawa, Aya Williams, et al.
Volume 69 Issue 9 - September 2015
This study investigated a gap between the treatment algorithm and the clinical practices for depression performed by early-career psychiatrists in Japan and the USA. The gap was greater in Japanese psychiatrists. Even though the small sample size is a limitation, this study is valuable due to its social relevance and creativity.

Rare heterozygous truncating variations and risk of autism spectrum disorder: Whole-exome sequencing of a multiplex family and follow-up study in a Japanese population
Emiko Inoue, Yuichiro Watanabe, et al.
Volume 69 Issue 8 - August 2015
A genome-wide analysis was performed for autism spectrum disorders in multiplex families, and two rare heterozygous truncating mutations (RPS24 Q191X and CD300LF P261fsX266) were identified. However, the same mutation was not found in another study including 667 individuals in the control group and 243 individuals in the autism spectrum disorder group. The results of the present study indicate that these two heterozygous truncating mutations are risk candidates for autism spectrum disorders. Our results may shed light on the genetic background of autism spectrum disorders in future.

Biological heterogeneity of obsessive–compulsive disorder: A voxel-based morphometric study based on dimensional assessment
Kayo Okada, Tomohiro Nakao, et al.
Volume 69 Issue 7 - July 2015
Abnormal orbitofrontal cortical–striatal–thalamic circuit is a well-known feature of obsessive-compulsive disorder (OCD). This study examined brain anatomy in OCD, and reported extensively reduced gray matter. Further, it was revealed that the part of the brain involved varied depending on the symptoms, suggesting that the neural basis of OCD differs depending on the symptoms.

White matter abnormalities in major depressive disorder with melancholic and atypical features: A diffusion tensor imaging study
Miho Ota, Takamasa Noda, et al.
Volume 69 Issue 6 - June 2015
This valuable study examined the structural changes in white matter using diffusion tensor imaging to clarify the neurobiological basis of major depressive disorder presenting with atypical features differing from the clinical manifestations, course, and drug reaction of melancholic depression.

Role of cortisol in patients at risk for psychosis mental state and psychopathological correlates: A systematic review
Evangelos Karanikas and Giorgos Garyfallos
Volume 69 Issue 5 - May 2015
Many studies to date have examined the role of cortisol, a stress hormone, in schizophrenia. This paper comprises a systematic review of 16 articles related to the role of cortisol in the pathology of the prodromal phase of schizophrenia, which has garnered particular attention recently.

Brain correlates of response inhibition in Internet gaming disorder
Chiao-Yun Chen, Mei-Feng Huang, et al.
Volume 69 Issue 4 - April 2015
Internet gaming disorder (IGD) is a psychiatric disorder recently proposed for inclusion in the Diagnostic and Statistical Manual of Mental Disorders (fifth edition) that warrants further study. The authors examined brain activity by functional magnetic resonance imaging during a Go/No-go task to investigate the subjects’ capability of simple reaction control, and found that activation of the supplementary motor area was low in patients with IGD, and the ability to control impulses is therefore reduced in IGD.


Unusual developmental pattern of brain lateralization in young boys with autism spectrum disorder: Power analysis with child-sized magnetoencephalography
Hirotoshi Hiraishi, Mitsuru Kikuchi, et al.
Volume 69 Issue 3 - March 2015

DSM-5-defined ‘mixed features’ and Benazzi's mixed depression: Which is practically useful to discriminate bipolar disorder from unipolar depression in patients with depression?
Minoru Takeshima and Takashi Oka
Volume 69 Issue 2 - February 2015

Near-infrared spectroscopy for examination of prefrontal activation during cognitive tasks in patients with major depressive disorder: A meta-analysis of observational studies
Huijun Zhang, Wentian Dong, et al.
Volume 69 Issue 1 - January 2015