Respirology

Cover image for Vol. 21 Issue 4

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Peter Eastwood

Impact Factor: 3.345

ISI Journal Citation Reports © Ranking: 2014: 15/58 (Respiratory System)

Online ISSN: 1440-1843

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  1. 1 - 58
  1. SERIES EDITORIAL—EPILOGUE

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  2. EDITORIALS

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      Targeting obesity in COPD through allied health therapies

      Christian R Osadnik and Vinicius Cavalheri

      Version of Record online: 30 MAY 2016 | DOI: 10.1111/resp.12821

  3. INVITED REVIEW SERIES

    1. Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes

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      HIV and COPD: a conspiracy of risk factors

      Umesh G. Lalloo, Sandy Pillay, Rosie Mngqibisa, Sabeer Abdool-Gaffar and Anish Ambaram

      Version of Record online: 30 MAY 2016 | DOI: 10.1111/resp.12806

  4. CORRESPONDENCE

  5. EDITORIALS

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  6. SYSTEMATIC REVIEW

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      Statins for the prevention and treatment of acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysis

      Bo Xiong, Chunbin Wang, Jie Tan, Yin Cao, Yanke Zou, Yuanqing Yao, Jun Qian, Shunkang Rong, Yuwen Huang and Jing Huang

      Version of Record online: 24 MAY 2016 | DOI: 10.1111/resp.12820

  7. ORIGINAL ARTICLES

    1. Upper airway microbial colonization in patients with neuromuscular disorders

      Florian Stehling, Nadine Pieper, Anastasios Bouikidis, Joerg Steinmann, Peter-Michael Rath and Uwe Mellies

      Version of Record online: 24 MAY 2016 | DOI: 10.1111/resp.12814

      This retrospective data analysis shows for the first time that advanced stages of lung volume restriction and cough insufficiency in patients with neuromuscular disorders are accompanied by microbial airway colonization. Treatment of chronic bacterial colonization/infection may offer a new therapeutic strategy to reduce respiratory morbidity of patients with neuromuscular disorders.

    2. Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

      Kak-Ming Ling, Erika N. Sutanto, Thomas Iosifidis, Elizabeth Kicic-Starcevich, Kevin Looi, Luke W. Garratt, Kelly M. Martinovich, Francis J. Lannigan, Darryl A. Knight, Stephen M. Stick and Anthony Kicic

      Version of Record online: 24 MAY 2016 | DOI: 10.1111/resp.12810

      We highlighted the role of TGF-β1 in maintaining normal airway epithelium homeostasis and demonstrated that the downregulation of TGF-β1 can contribute to dysregulated repair observed in asthmatic airway epithelium.

    3. TNF and IL-1β exposure increases airway narrowing but does not alter the bronchodilatory response to deep inspiration in airway segments

      Thomas K. Ansell, Howard W. Mitchell, Peter K. McFawn and Peter B. Noble

      Version of Record online: 20 MAY 2016 | DOI: 10.1111/resp.12800

      It is unclear whether the attenuated bronchodilatory response to deep inspiration in asthma is related to an inflammatory environment. Using whole bronchial segments in vitro, we show that culture with pro-inflammatory cytokines, tumour necrosis factor and interleukin-1β, increases airway narrowing but does not affect the bronchodilatory response to deep inspiration.

    4. Legionnaires' disease caused by Legionella longbeachae: Clinical features and outcomes of 107 cases from an endemic area

      Heather L. Isenman, Stephen T. Chambers, Alan D. Pithie, Sharyn L.S. MacDonald, Justin M. Hegarty, Joanna L. Fenwick, Michael J. Maze, Sarah C.L. Metcalf and David R. Murdoch

      Version of Record online: 19 MAY 2016 | DOI: 10.1111/resp.12808

      Descriptions of Legionella longbeachae infection are limited to case reports or small case series. We reviewed the clinical characteristics of 107 cases of L. longbeachae pneumonia from a single centre. Characteristics of L. longbeachae pneumonia are similar to those reported for community-acquired pneumonia in general except for the spring/summer seasonality.

  8. Original Articles

    1. Usefulness of transcutaneous PCO2 to assess nocturnal hypoventilation in restrictive lung disorders

      Marjolaine Georges, Danièle Nguyen-Baranoff, Lucie Griffon, Clement Foignot, Philippe Bonniaud, Philippe Camus, Jean-Louis Pepin and Claudio Rabec

      Version of Record online: 17 MAY 2016 | DOI: 10.1111/resp.12812

      This study demonstrates that compared with nocturnal transcutaneous PCO2, the combination of morning arterial blood gases and nocturnal pulse oxymetry underestimates the occurrence of nocturnal hypoventilation in one third of patients with neuromuscular and thoracic cage disorders at risk of respiratory failure

    2. Bile acids induce activation of alveolar epithelial cells and lung fibroblasts through farnesoid X receptor-dependent and independent pathways

      Bi Chen, Hou-Rong Cai, Shan Xue, Wen-Jie You, Bin Liu and Han-Dong Jiang

      Version of Record online: 17 MAY 2016 | DOI: 10.1111/resp.12815

      This study explores the role of bile acid microaspiration and Farnesoid X receptor (FXR) activation in the pathogenesis of idiopathic pulmonary fibrosis and demonstrates that bile acids could induce activation of alveolar epithelial cells and lung fibroblasts via FXR-dependent and independent mechanisms.

    3. Effect of long-term treatment with corticosteroids on skeletal muscle strength, functional exercise capacity and health status in patients with interstitial lung disease

      Masatoshi Hanada, Noriho Sakamoto, Yuji Ishimatsu, Tomoyuki Kakugawa, Yasushi Obase, Ryo Kozu, Hideaki Senjyu, Koichi Izumikawa, Hiroshi Mukae and Shigeru Kohno

      Version of Record online: 13 MAY 2016 | DOI: 10.1111/resp.12807

      The effects of long-term corticosteroid use on skeletal muscle strength, exercise capacity, ADL and health status in ILD were investigated. Peripheral muscle strength was reduced in subjects on corticosteroids compared with untreated controls, but exercise capacity, ADL and health status were not different between the groups.

  9. Correspondences

    1. Effect of smoking status on the efficacy of the SMART regimen in high risk asthma – Reply

      Janine Pilcher, Mitesh Patel, Helen Reddel, Dominick Shaw, Mark Weatherall and Richard Beasley

      Version of Record online: 2 MAY 2016 | DOI: 10.1111/resp.12803

  10. Original Articles

    1. Bronchodilator responsiveness of peripheral airways in smokers with normal spirometry

      Kanika Jetmalani, David G. Chapman, Cindy Thamrin, Claude S. Farah, Norbert Berend, Cheryl M. Salome and Gregory G. King

      Version of Record online: 2 MAY 2016 | DOI: 10.1111/resp.12802

      Conductive airway function is abnormal in 24% of smokers with normal spirometry and normalizes in 18% after bronchodilation, representing smoking induced increased bronchomotor tone. Whereas, acinar airway function is abnormal in 38% of smokers and remains abnormal in 30% after bronchodilation, potentially representing inflammation or structural changes.

  11. INVITED REVIEW SERIES

    1. Idiopathic Interstitial Pneumonia

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      Acute and subacute idiopathic interstitial pneumonias

      Hiroyuki Taniguchi and Yasuhiro Kondoh

      Version of Record online: 28 APR 2016 | DOI: 10.1111/resp.12786

  12. Original Articles

    1. Poor agreement between diagnostic tests for latent tuberculosis infection among HIV-infected persons in Hong Kong

      Chi Chiu Leung, Kenny Chan, Wing Cheong Yam, Man Po Lee, Chi Kuen Chan, Ka Hing Wong, Pak Leung Ho, Ida Mak and Cheuk Ming Tam

      Version of Record online: 28 APR 2016 | DOI: 10.1111/resp.12805

      Major discordance, high reversion rates and low tuberculosis incidence were observed among test-positive subjects for the three available tests for latent tuberculosis infection in the annual screening of HIV-infected persons in an intermediate tuberculosis burden area with high BCG vaccination coverage and low ongoing tuberculosis transmission.

  13. Invited Review Series: Lung Cancer Practice, Implementing Evidence Around the World

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      Immunotherapy for lung cancer

      Antonius Steven, Scott A. Fisher and Bruce W. Robinson

      Version of Record online: 21 APR 2016 | DOI: 10.1111/resp.12789

  14. Invited Review Series: Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes

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      Non-pharmacological treatments for COPD

      Patrick Mulhall and Gerard Criner

      Version of Record online: 21 APR 2016 | DOI: 10.1111/resp.12782

  15. Original Articles

    1. Effect of CPAP Withdrawal on myocardial perfusion in OSA: A randomized controlled trial

      Esther I. Schwarz, Christian Schlatzer, Julia Stehli, Philipp A. Kaufmann, Konrad E. Bloch, John R. Stradling and Malcolm Kohler

      Version of Record online: 20 APR 2016 | DOI: 10.1111/resp.12798

      CPAP is suggested to reduce the vascular risk in OSA. This randomized controlled trial tested whether recurrence of OSA by therapy withdrawal has an impact on myocardial perfusion. OSA recurrence has no adverse effect on myocardial perfusion and microvascular function, despite clinically relevant increases in blood pressure and heart rate.

    2. Craniofacial phenotyping for prediction of obstructive sleep apnoea in a Chinese population

      Kate Sutherland, Richard W. W. Lee, Peter Petocz, Tat On Chan, Susanna Ng, David S. Hui and Peter A. Cistulli

      Version of Record online: 15 APR 2016 | DOI: 10.1111/resp.12792

      Craniofacial phenotyping by quantitative photography is a simple method for craniofacial assessment, which may have research and clinical applications. Facial photographical variables have previously shown predictive utility for OSA risk in a Caucasian sleep clinic population. Although there are ethnic differences in craniofacial OSA risk factors, facial photography performs similarly in a Chinese sleep clinic population.

    3. Rapid on-site evaluation with the Hemacolor rapid staining method of medical thoracoscopy biopsy specimens for the management of pleural disease

      Ilias Porfyridis, Georgios Georgiadis, Michalis Michael, Frangiskos Frangopoulos, Paris Vogazianos, Alexis Papadopoulos, Panayiota Kara, Charis Charalampous and Andreas Georgiou

      Version of Record online: 15 APR 2016 | DOI: 10.1111/resp.12799

      To evaluate the diagnostic performance of rapid on-site evaluation (ROSE) of medical thoracoscopy (MT) biopsy specimens. ROSE during MT was found to have high accuracy for predicting malignancy. ROSE can provide an on-site preliminary diagnosis and can be beneficial, especially in cases with inconclusive macroscopic appearance.

    4. Late-onset noninfectious interstitial lung disease following autologous haematopoietic stem cell transplantation in paediatric patients

      Yoon-Kyoung Lee, Rimm Huh, Jihyun Kim, Kangmo Ahn, Ki Woong Sung and Joongbum Cho

      Version of Record online: 12 APR 2016 | DOI: 10.1111/resp.12787

      We investigated noninfectious interstitial lung disease after autologous transplantation in 340 paediatric patients. The incidence was 2.4%. The symptom onset was late, and the prognosis was poor. High-dose cyclophosphamide and female gender were risk factors of interstitial lung disease.

    5. Flexible bronchoscopy-induced massive bleeding: A 12-year multicentre retrospective cohort study

      Guo-Wu Zhou, Wei Zhang, Yu-Chao Dong, Hai-Dong Huang, Chengping Hu, Jiayuan Sun, Faguang Jin, Ye Gu, Qiang Li and Shiyue Li

      Version of Record online: 8 APR 2016 | DOI: 10.1111/resp.12784

      There is a scarcity of information on the incidence and outcome of flexible bronchoscopy-induced massive bleeding. In this large cohort study, the results indicated a low prevalence but high fatality of such bleeding. Age, bleeding location, bleeding volume, circulation condition and emergency surgery were independent prognostic factors.

    6. Suspected pulmonary embolism in patients with pulmonary fibrosis: Discordance between ventilation/perfusion SPECT and CT pulmonary angiography

      Gabriela Leuschner, Vera Wenter, Katrin Milger, Gregor S. Zimmermann, Sandhya Matthes, Felix G. Meinel, Sebastian Lehner, Claus Neurohr, Jürgen Behr and Nikolaus Kneidinger

      Version of Record online: 7 APR 2016 | DOI: 10.1111/resp.12797

      The purpose of the study was to investigate the concordance of V/Q-SPECT and CTPA in patients with pulmonary fibrosis and suspicion of pulmonary embolism. V/Q-SPECT resulted in substantially more positive results than CTPA. When making treatment decisions, clinicians should be aware of the high rate of discordant findings.

    7. Low prevalence of obstructive lung disease in a suburban population of Malaysia: A BOLD collaborative study

      Li Cher Loh, Abdul Rashid, Siti Sholehah, Louisa Gnatiuc, Jaymini H. Patel and Peter Burney

      Version of Record online: 7 APR 2016 | DOI: 10.1111/resp.12793

      As part of BOLD collaboration, the estimated prevalence of COPD in a suburban population of Malaysia was low compared with most sites globally. Cigarette smoking, biomass burning and exposure to dusty jobs are risk factors for COPD development. This represented the first robust population-based epidemiology data for Malaysia.

    8. Persistence with inhaled corticosteroids reduces the risk of exacerbation among adults with asthma: A real-world investigation

      Giovanni Corrao, Andrea Arfè, Federica Nicotra, Arianna Ghirardi, Adriano Vaghi, Roberto De Marco, Alberto Pesci, Luca Merlino, Antonella Zambon and on behalf of the CRD Real-World Evidence Scientific Board

      Version of Record online: 7 APR 2016 | DOI: 10.1111/resp.12791

      We provide further evidence of the importance of persistence with inhaled corticosteroids therapy for asthma control by adding data from a real-life setting to evidence from randomized controlled trials. Specifically, drug utilization patterns, in the real-world setting described, offer evidence that persistence with inhaled corticosteroids reduces the risk of asthma exacerbations.

    9. Impact of weekend admission on in-hospital mortality in severe community-acquired pneumonia patients in Japan

      Hironori Uematsu, Susumu Kunisawa, Kazuto Yamashita, Kiyohide Fushimi and Yuichi Imanaka

      Version of Record online: 3 APR 2016 | DOI: 10.1111/resp.12788

      Patients with severe community-acquired pneumonia admitted on weekends had higher risk of in-hospital mortality than patients admitted on weekdays. A possible reason for the increased mortality may be the lower implementation of microbiological testing per guidelines on weekends.

    10. Telehealth to improve asthma control in pregnancy: A randomized controlled trial

      Elida Zairina, Michael J. Abramson, Christine F. McDonald, Jonathan Li, Thanuja Dharmasiri, Kay Stewart, Susan P. Walker, Eldho Paul and Johnson George

      Version of Record online: 31 MAR 2016 | DOI: 10.1111/resp.12773

      This study evaluated the efficacy of a telehealth programme, supported by a handheld respiratory device for optimising asthma management in pregnant women. At the end of the study, participants in the intervention group showed greater improvement in asthma control and asthma-related quality of life than the control group.

    11. Coordination between respiration and swallowing during non-invasive positive pressure ventilation

      Ryuji Hori, Masaaki Isaka, Kazuhiko Oonishi, Toru Yabe and Yoshitaka Oku

      Version of Record online: 30 MAR 2016 | DOI: 10.1111/resp.12790

      We evaluated the coordination between respiration and swallowing during non-invasive artificial ventilation in healthy subjects and found that the occurrence rate of inspiration after swallowing is increased while using BiPAP. The results suggest that SNIF may trigger inspiratory support during BiPAP treatment, increasing the risk of aspiration.

    12. Infection site is predictive of outcome in acute lung injury associated with severe sepsis and septic shock

      Seitaro Fujishima, Satoshi Gando, Saitoh Daizoh, Shigeki Kushimoto, Hiroshi Ogura, Toshihiko Mayumi, Kiyotsugu Takuma, Joji Kotani, Norio Yamashita, Ryosuke Tsuruta, Naoshi Takeyama, Shin-ichiro Shiraishi, Tsunetoshi Araki, Koichiro Suzuki, Hiroto Ikeda, Yasuo Miki, Yasushi Suzuki, Yoshihiro Yamaguchi, Naoki Aikawa and Japanese Association for Acute Medicine Sepsis Registry (JAAM SR) Study Group

      Version of Record online: 30 MAR 2016 | DOI: 10.1111/resp.12769

      Using a secondary analysis of a prospective multicenter study for severe sepsis and septic shock, the infection site was found to be an independent prognostic factor together with organ dysfunctions for septic patients with acute lung injury (ALI) but not for those without ALI.

  16. Invited Review Series: Unravelling the Many Faces of COPD to Optimize Its Care and Outcomes

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      Acute exacerbation of COPD

      Fanny W. Ko, Ka Pang Chan, David S. Hui, John R. Goddard, Janet G. Shaw, David W. Reid and Ian A. Yang

      Version of Record online: 30 MAR 2016 | DOI: 10.1111/resp.12780

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      Pulmonary vasculature in COPD: The silent component

      Isabel Blanco, Lucilla Piccari and Joan Albert Barberà

      Version of Record online: 30 MAR 2016 | DOI: 10.1111/resp.12772

  17. Original Articles

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      Curcumin enhances human macrophage control of Mycobacterium tuberculosis infection

      Xiyuan Bai, Rebecca E. Oberley-Deegan, An Bai, Alida R. Ovrutsky, William H. Kinney, Michael Weaver, Gong Zhang, Jennifer R. Honda and Edward D. Chan

      Version of Record online: 24 MAR 2016 | DOI: 10.1111/resp.12762

      Summary at a Glance

      The effects of curcumin (a polyphenol of tumeric) on Mycobacterium tuberculosis (MTB) infection using human macrophages were investigated in this study. Curcumin reduced the intracellular burden of MTB in infected macrophages through inhibition of NFκB activation resulting in the induction of caspase-3-dependent apoptosis and autophagy.

  18. Systematic Reviews

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      Health-related quality of life, comorbidities and mortality in pulmonary nontuberculous mycobacterial infections: A systematic review

      Man Wah Yeung, Edwin Khoo, Sarah K. Brode, Frances B. Jamieson, Hiroyuki Kamiya, Jeffrey C. Kwong, Liane Macdonald, Theodore K. Marras, Kozo Morimoto and Beate Sander

      Version of Record online: 23 MAR 2016 | DOI: 10.1111/resp.12767

  19. Year in Reviews

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  20. Original Articles

    1. Factors associated with radiologic progression of non-cystic fibrosis bronchiectasis during long-term follow-up

      Jisoo Park, Sejoong Kim, Yeon Joo Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Kyoung-won Lee, Choon-Taek Lee and Jae Ho Lee

      Version of Record online: 21 MAR 2016 | DOI: 10.1111/resp.12768

      The radiologic progression of non-CF bronchiectasis was associated with lower BMI and isolation of Pseudomonas aeruginosa in respiratory specimens.

    2. Clinical features of usual interstitial pneumonia with anti-neutrophil cytoplasmic antibody in comparison with idiopathic pulmonary fibrosis

      Chiaki Hosoda, Tomohisa Baba, Eri Hagiwara, Hiroyuki Ito, Norikazu Matsuo, Hideya Kitamura, Tae Iwasawa, Koji Okudela, Tamiko Takemura and Takashi Ogura

      Version of Record online: 19 MAR 2016 | DOI: 10.1111/resp.12763

      This is the first study to report on a direct comparison of pathologically proven usual interstitial pneumonia associated with MPO-ANCA (ANCA/UIP) and idiopathic pulmonary fibrosis (IPF). This study shows some radiological and pathological characteristics and better responsiveness to immunosuppressive therapy in ANCA/UIP compared with IPF.

    3. Ultrasound assessment of diaphragmatic function in patients with amyotrophic lateral sclerosis

      Riccardo Fantini, Jessica Mandrioli, Stefano Zona, Federico Antenora, Andrea Iattoni, Marco Monelli, Nicola Fini, Roberto Tonelli, Enrico Clini and Alessandro Marchioni

      Version of Record online: 19 MAR 2016 | DOI: 10.1111/resp.12759

      This study demonstrates a significant correlation between ultrasound based diaphragm thickness variation and lung impairment in ALS patients. We propose a new ultrasound index of the diaphragm, ΔTmax, which shows a better accuracy than FVC and SNIP test, and that could help clinicians on patient counselling regarding NIV.

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      Histopathology of removed indwelling pleural catheters from patients with malignant pleural diseases

      Claire L. Tobin, Rajesh Thomas, Siaw Ming Chai, Amanda Segal and Y. C. Gary Lee

      Version of Record online: 19 MAR 2016 | DOI: 10.1111/resp.12777

      We report for the first time the histological findings of indwelling pleural catheters removed from patients with underlying pleural malignancies. Analyses showed cancer cells in the luminal contents in some cases but no evidence of direct tumour invasion or growth on the catheter surfaces, even in a high mesothelioma prevalence setting.

  21. Reviews

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  22. Original Articles

    1. Therapy with proton-pump inhibitors for gastroesophageal reflux disease does not reduce the risk for severe exacerbations in COPD

      Luzia Baumeler, Eleni Papakonstantinou, Branislava Milenkovic, Alicia Lacoma, Renaud Louis, Joachim G. Aerts, Tobias Welte, Konstantinos Kostikas, Francesco Blasi, Wim Boersma, Antoni Torres, Gernot G.U. Rohde, Lucas Boeck, Janko Rakic, Andreas Scherr, Michael Tamm and Daiana Stolz

      Version of Record online: 11 MAR 2016 | DOI: 10.1111/resp.12758

      We prospectively evaluated 638 COPD patients and provide evidence that COPD patients receiving anti-acid therapy with PPI for GERD remain at high risk of frequent and severe exacerbations independently of adjusted Charlson score, FEV1% predicted, BODE index, MMRC and medication for comorbidities.

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      Mother's smoking and complex lung function of offspring in middle age: A cohort study from childhood

      Jennifer L. Perret, Haydn Walters, David Johns, Lyle Gurrin, John Burgess, Adrian Lowe, Bruce Thompson, James Markos, Stephen Morrison, Paul Thomas, Christine McDonald, Richard Wood-Baker, John Hopper, Cecilie Svanes, Graham Giles, Michael Abramson, Melanie Matheson and Shyamali Dharmage

      Version of Record online: 11 MAR 2016 | DOI: 10.1111/resp.12750

      Heavy maternal smoking during childhood was associated with post-bronchodilator airflow obstruction for middle-aged offspring, and the exposure itself augmented the effects of personal smoking on gas transfer factor. This study suggests that early life exposure might increase an individual's susceptibility for chronic obstructive pulmonary disease, especially related to personal smoking in later life.

    3. Serum activin-A as a predictive and prognostic marker in critically ill patients with sepsis

      Jung-Kyu Lee, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Chang Hoon Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han and Sang-Min Lee

      Version of Record online: 10 MAR 2016 | DOI: 10.1111/resp.12751

    4. Prevalence of sleep-disordered breathing in a multiethnic Asian population in Singapore: A community-based study

      Adeline Tan, Yan Yi Cheung, Jason Yin, Wei-Yen Lim, Linda W.L. Tan and Chi-Hang Lee

      Version of Record online: 29 FEB 2016 | DOI: 10.1111/resp.12747

      We found an estimated population prevalence of moderate-to-severe SDB of 30.5% in Singapore. Ninety-one percent of subjects with moderate-to-severe SDB were previously undiagnosed. Moderate-to-severe SDB prevalence varied across Chinese, Malay and Indian people. Indian people had lower odds of moderate-to-severe SDB compared to Chinese people after adjustment for BMI, age and sex.

  23. Reviews

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      Mouse models of acute exacerbations of allergic asthma

      Rakesh K. Kumar, Cristan Herbert and Paul S. Foster

      Version of Record online: 28 FEB 2016 | DOI: 10.1111/resp.12760

  24. Original Articles

    1. Should we treat obesity in COPD? The effects of diet and resistance exercise training

      Vanessa M. McDonald, Peter G. Gibson, Hayley A. Scott, Penelope J. Baines, Michael J. Hensley, Jeffrey J. Pretto and Lisa G. Wood

      Version of Record online: 24 FEB 2016 | DOI: 10.1111/resp.12746

    2. Effect of smoking status on the efficacy of the SMART regimen in high risk asthma

      Janine Pilcher, Mitesh Patel, Helen K. Reddel, Alison Pritchard, Peter Black, Dominick Shaw, Shaun Holt, Mark Weatherall and Richard Beasley

      Version of Record online: 21 FEB 2016 | DOI: 10.1111/resp.12740

      SUMMARY AT A GLANCE

      This study has shown that the favourable efficacy/safety profile of single combination-inhaled corticosteroid/long acting beta-agonist inhaler maintenance and reliever therapy regimen in adult patients with high risk asthma is not influenced by smoking status.

  25. Scientific Letters

    1. Breathing-related changes of respiratory resistance in vocal cord dysfunction

      Iulia Ioan, François Marchal, Laurent Coffinet, Laurianne Coutier, Claude Bonabel, Bruno Demoulin, Romain Clisson, Cyril Schweitzer and Silvia Varechova

      Version of Record online: 22 JAN 2016 | DOI: 10.1111/resp.12735

  26. Scientific Letter

    1. Medical thoracoscopy: Survey of current practice—How successful are medical thoracoscopists at predicting malignancy?

      Robert J. Hallifax, John P. Corcoran, Ioannis Psallidas and Najib M. Rahman

      Version of Record online: 30 DEC 2015 | DOI: 10.1111/resp.12725

  27. Invited Review Series: Idiopathic Interstitial Pneumonia—Part 3: General Management Issues

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      Lung transplantation in IIP: A review

      A. Whitney Brown, Hatice Kaya and Steven D. Nathan

      Version of Record online: 3 DEC 2015 | DOI: 10.1111/resp.12691

  28. Invited Review Series: Idiopathic Interstitial Pneumonia-Part 3: General Management Issues

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  29. Invited Review Series: Idiopathic Interstitial Pneumonia—Part 3: General Management Issues

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      Exercise pathophysiology and the role of oxygen therapy in idiopathic interstitial pneumonia

      Lauren K. Troy, Iven H. Young, Edmund M.T. Lau and Tamera J. Corte

      Version of Record online: 29 SEP 2015 | DOI: 10.1111/resp.12650

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