Diabetes, Obesity and Metabolism

Cover image for Vol. 19 Issue 1

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: R. Donnelly and A. Garber

Impact Factor: 6.198

ISI Journal Citation Reports © Ranking: 2015: 13/133 (Endocrinology & Metabolism)

Online ISSN: 1463-1326


  1. 1 - 48


    1. Cardiovascular Effects of GLP-1 Receptor Agonist Therapies in Patients with Type-1 Diabetes

      Manfredi Rizzo, Ali A. Rizvi and Giorgio Sesti

      Accepted manuscript online: 18 JAN 2017 07:20AM EST | DOI: 10.1111/dom.12883


    1. Immunohistochemical Assessment of Glucagon-like Peptide 1 Receptor (GLP-1R) Expression in the Pancreas of Patients with Type 2 Diabetes

      Rikke Kaae Kirk, Charles Pyke, Matthias G. von Herrath, Jane Preuss Hasselby, Lars Pedersen, Pia Gottrup Mortensen, Lotte Bjerre Knudsen and Ken Coppieters

      Accepted manuscript online: 17 JAN 2017 07:30AM EST | DOI: 10.1111/dom.12879

    2. Effects of beta-blockers on all-cause mortality in patients with type 2 diabetes and coronary heart disease

      Tetsuro Tsujimoto, Takehiro Sugiyama and Hiroshi Kajio

      Accepted manuscript online: 17 JAN 2017 05:30AM EST | DOI: 10.1111/dom.12878

    3. Effect of valsartan on kidney outcomes in people with impaired glucose tolerance

      Gemma Currie, M. Angelyn Bethel, Björn Holzhauer, Steven M. Haffner, Rury R. Holman and John J. V. McMurray

      Accepted manuscript online: 17 JAN 2017 04:00AM EST | DOI: 10.1111/dom.12877


    1. Renal Safety of Canagliflozin, a Sodium Glucose Co-transporter 2 Inhibitor, in Patients With Type 2 Diabetes Mellitus

      Mehul Desai, Yshai Yavin, Dainius Balis, Don Sun, John Xie, William Canovatchel and Norm Rosenthal

      Accepted manuscript online: 12 JAN 2017 11:30PM EST | DOI: 10.1111/dom.12876

    2. Efficacy and safety of fixed-dose combination therapy alogliptin plus metformin in Asian patients with type 2 diabetes: a phase 3 trial

      Linong Ji, Ling Li, Jian Kuang, Tao Yang, Dong-Jun Kim, Azidah Abdul Kadir, Chien-Ning Huang and Douglas Lee

      Accepted manuscript online: 11 JAN 2017 05:35AM EST | DOI: 10.1111/dom.12875


    1. Physician Step prescription and Monitoring to improve ARTERial health (SMARTER): a randomized controlled trial in type 2 diabetes and hypertension

      Kaberi Dasgupta, Ellen Rosenberg, Lawrence Joseph, Alexandra B. Cooke, Luc Trudeau, Simon L. Bacon, Deborah Chan, Mark Sherman, Rémi Rabasa-Lhoret and Stella S. Daskalopoulou

      Accepted manuscript online: 11 JAN 2017 02:50AM EST | DOI: 10.1111/dom.12874

    2. Upper and/or lower gastrointestinal adverse events with GLP-1 receptor agonists: incidences and consequences

      Michael Horowitz, Vanita R. Aroda, Jenny Han, Elise Hardy and Chris K. Rayner

      Accepted manuscript online: 6 JAN 2017 02:20AM EST | DOI: 10.1111/dom.12872

    3. Dual Role of IL-1β in Islet Amyloid Formation and its β-Cell Toxicity: Implications in Type 2 Diabetes and Islet Transplantation

      Yoo Jin Park, Garth L. Warnock, Ziliang Ao, Nooshin Safikhan, Mark Meloche, Ali Asadi, Timothy J. Kieffer and Lucy Marzban

      Accepted manuscript online: 6 JAN 2017 02:20AM EST | DOI: 10.1111/dom.12873

    4. Efficacy and Safety of Adding Evogliptin versus Sitagliptin In Metformin-Treated Patients With Type 2 Diabetes: A 24-week Randomised, Controlled Trial With Open Label Extension

      Sang-Mo Hong, Cheol-Young Park, Dong-Min Hwang, Kyung Ah Han, Chang Beom Lee, Choon Hee Chung, Kun-Ho Yoon, Ji-Oh Mok, Kyong Soo Park and Sung-Woo Park

      Accepted manuscript online: 6 JAN 2017 02:20AM EST | DOI: 10.1111/dom.12870

    5. Relationship of glycated haemoglobin and reported hypoglycaemia to cardiovascular outcomes in patients with type 2 diabetes and recent acute coronary syndromes: the EXAMINE trial

      Simon R. Heller, Richard M. Bergenstal, William B. White, Stuart Kupfer, George L. Bakris, William C. Cushman, Cyrus R. Mehta, Steven E. Nissen, Craig A. Wilson, Faiez Zannad, Yuyin Liu, Noah M. Gourlie, Christopher P. Cannon and for the EXAMINE Investigators

      Accepted manuscript online: 6 JAN 2017 02:15AM EST | DOI: 10.1111/dom.12871


    1. Effect of gemigliptin on glycemic variability in patients with type 2 diabetes

      Se E. Park, Byung W. Lee, Jae H. Kim, Woo J. Lee, Jae H. Cho, Chang H. Jung, Seung H. Lee, Sunghwan. Suh, Gwong C. Hur, Sung H. Kim, Young H. Jang, Cheol Y. Park and STABLE Study Group

      Accepted manuscript online: 6 JAN 2017 01:20AM EST | DOI: 10.1111/dom.12869


    1. An alternative approach to modelling HbA1c trajectories in patients with type 2 diabetes mellitus

      Phil McEwan, Hayley Bennett, Lei Qin, Klas Bergenheim, Jason Gordon and Marc Evans

      Accepted manuscript online: 27 DEC 2016 08:53AM EST | DOI: 10.1111/dom.12865

    2. Efficacy and Safety of Gemigliptin, a Dipeptidyl Peptidase-4 Inhibitor, in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Combination Treatment of Metformin and Sulfonylurea: a 24-week, multicenter, randomized, double-blind, placebo-controlled study (TROICA Study)

      Chang Ho Ahn, Kyung Ah Han, Jae Myung Yu, Joo Young Nam, Kyu Jeung Ahn, Tae Keun Oh, Hyoung Woo Lee, Dae Ho Lee, Jaetaek Kim, Choon Hee Chung, Tae Sun Park, Byung Joon Kim, Seok Won Park, Hyeong Kyu Park, Kwang Jae Lee, Sang-Wook Kim, Jeong Hyun Park, Kwan Pyo Ko, Chong Hwa Kim, Hyunjin Lee, Hak Chul Jang and Kyong Soo Park

      Accepted manuscript online: 27 DEC 2016 08:36AM EST | DOI: 10.1111/dom.12866

    3. Managing glycaemia in older people with type 2 diabetes: a retrospective, primary care based cohort study, with economic assessment of patient outcomes

      Jason Gordon, Phil McEwan, Marc Evans, Jorge Puelles and Alan Sinclair

      Accepted manuscript online: 27 DEC 2016 08:36AM EST | DOI: 10.1111/dom.12867

    4. Efficacy, Safety, and Albuminuria-Reducing Effect of Gemigliptin in Korean Type 2 Diabetes Patients with Moderate to Severe Renal Impairment: A 12-Week, Double-blind Randomized Study (the GUARD Study)

      Sun A. Yoon, Byoung G. Han, Sung G. Kim, Sang Y. Han, Young I. Jo, Kyung H. Jeong, Kook H. Oh, Hyoung C. Park, Sun H. Park, Shin W. Kang, Ki R. Na, Sun W. Kang, Nam H. Kim, Young H. Jang, Seong H. Shin and Dae R. Cha

      Accepted manuscript online: 25 DEC 2016 11:41PM EST | DOI: 10.1111/dom.12863


    1. The effects of atrasentan on urinary metabolites in patients with type 2 diabetes and nephropathy

      Michelle J Pena, Dick de Zeeuw, Dennis Andress, John J Brennan, Ricardo Correa-Rotter, Blai Coll, Donald E Kohan, Hirofumi Makino, Vlado Perkovic, Giuseppe Remuzzi, Sheldon W Tobe, Robert Toto, Hans-Henrik Parving, Shoba Sharma, Tom Corringham, Kumar Sharma and Hiddo JL Heerspink

      Accepted manuscript online: 25 DEC 2016 11:40PM EST | DOI: 10.1111/dom.12864


    1. Metabolic effects of Lactobacillus reuteri DSM 17938 in Patients with Type 2 Diabetes: A Randomized Controlled Trial

      Reza Mobini, Valentina Tremaroli, Marcus Ståhlman, Fredrik Karlsson, Max Levin, Maria Ljungberg, Maja Sohlin, Heléne Bertéus Forslund, Rosie Perkins, Fredrik Bäckhed and Per-Anders Jansson

      Accepted manuscript online: 23 DEC 2016 06:53AM EST | DOI: 10.1111/dom.12861

    2. Treatment of prednisolone-induced hyperglycaemia in hospitalized patients: Insights from a randomized-controlled study

      Anjana Radhakutty, Jessica L. Stranks, Brenda L. Mangelsdorf, Sophie M. Drake, Gregory W. Roberts, Anthony T. Zimmermann, Stephen N. Stranks, Campbell H. Thompson and Morton G. Burt

      Accepted manuscript online: 20 DEC 2016 03:50AM EST | DOI: 10.1111/dom.12859


    1. Canagliflozin versus placebo for post-bariatric patients with persistent type II diabetes; a randomized controlled trial (CARAT)

      Karim Khensier and Sangeeta Kashyap

      Accepted manuscript online: 20 DEC 2016 03:50AM EST | DOI: 10.1111/dom.12860


    1. SGLT2 inhibitor use and dietary carbohydrate intake in Japanese individuals with type 2 diabetes: a randomized, open-label, 3-arm parallel comparative exploratory study

      Daisuke Yabe, Masahiro Iwasaki, Hitoshi Kuwata, Takuya Haraguchi, Yoshiyuki Hamamoto, Takeshi Kurose, Kiminobu Sumita, Hitoshi Yamazato, Shigeto Kanada and Yutaka Seino

      Accepted manuscript online: 19 DEC 2016 03:03AM EST | DOI: 10.1111/dom.12848


    1. Understanding and overcoming metformin gastrointestinal intolerance

      Fabrice Bonnet and André Scheen

      Accepted manuscript online: 17 DEC 2016 02:45AM EST | DOI: 10.1111/dom.12854


    1. Evaluation of the Counter-regulatory Responses to Hypoglycemia in Patients with Type 1 Diabetes during Opiate Receptor Blockade with Naltrexone.

      Sarita Naik, Renata Belfort-DeAguiar, Anne-Sophie Sejling, Barbara Szepietowska and Robert S. Sherwin

      Accepted manuscript online: 17 DEC 2016 02:45AM EST | DOI: 10.1111/dom.12855


    1. Quantitative and longitudinal imaging of intramuscular transplanted islets of Langerhans with SPECT using [123I]IBZM

      Stefanie M.A. Willekens, Inge van der Kroon, Desirée Bos, Lieke Joosten, Cathelijne Frielink, Otto C. Boerman, Maarten Brom and Martin Gotthardt

      Accepted manuscript online: 17 DEC 2016 02:45AM EST | DOI: 10.1111/dom.12857


    1. Similar pharmacokinetics and pharmacodynamics of rapid-acting insulin lispro products SAR342434 and US- and EU-approved Humalog® in subjects with type 1 diabetes

      C. Kapitza, I. Nowotny, A. Lehmann, K. Bergmann, B. Rotthaeuser, L. Nosek and R. Becker

      Accepted manuscript online: 17 DEC 2016 02:45AM EST | DOI: 10.1111/dom.12856

    2. Efficacy and safety of dapagliflozin over 1 year as add-on to insulin therapy in Japanese patients with type 2 diabetes: DAISY trial

      E. Araki, Y. Onishi, M. Asano, H. Kim and T. Yajima

      Accepted manuscript online: 17 DEC 2016 02:45AM EST | DOI: 10.1111/dom.12853

    3. MD-Logic Overnight Type 1 Diabetes Control in Home Settings: Multicenter, Multinational, Single blind, Randomized Trial

      Revital Nimri, Natasa Bratina, Olga Kordonouri, Magdalena Avbelj Stefanija, Maryam Fath, Torben Biester, Ido Muller, Eran Atlas, Shahar Miller, Aviel Fogel, Moshe Phillip, Thomas Danne and Tadej Battelino

      Accepted manuscript online: 16 DEC 2016 12:00AM EST | DOI: 10.1111/dom.12852

    4. Comparison of Exposure Response Relationship of Atrasentan between North American and Asian Populations

      Hiddo J. L. Heerspink, Hirofumi Makino, Dennis Andress, John J. Brennan, Ricardo Correa-Rotter, Blai Coll, Justin Wade Davis, Ken Idler, Donald E. Kohan, Mohan Liu, Vlado Perkovic, Giuseppe Remuzzi, Sheldon W. Tobe, Robert Toto, Hans-Henrik Parving and Dick de Zeeuw

      Accepted manuscript online: 15 DEC 2016 11:50PM EST | DOI: 10.1111/dom.12851

    5. Effect of varying degrees of renal impairment on the pharmacokinetics and tolerability of taspoglutide

      Mylène Giraudon, Stefan Sturm, Nathalie Lambert, Markus Niggli, Jochen Brumm, Bernhard Mangold and Christophe Schmitt

      Accepted manuscript online: 15 DEC 2016 11:35PM EST | DOI: 10.1111/dom.12850

    6. Efficacy and Safety of Glucagon-like peptide-1 receptor agonists in type 2 diabetes Systematic review and mixed-treatment comparison analysis

      Zin Z Htike, Francesco Zaccardi, Dimitris Papamargaritis, David R Webb, Kamlesh Khunti and Melanie J Davies

      Accepted manuscript online: 15 DEC 2016 11:25PM EST | DOI: 10.1111/dom.12849

    7. Once Weekly Dulaglutide 1.5 mg Restores Insulin Secretion in Response to Intravenous Glucose Infusion

      Amparo de la Peña, Corina Loghin, Xuewei Cui, Xin Zhang, Christoph Kapitza and Ronan P. Kelly

      Accepted manuscript online: 15 DEC 2016 06:02AM EST | DOI: 10.1111/dom.12847


    1. Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor

      Christoffer Clemmensen, Christinna V. Jørgensen, Sanela Smajilovic and Hans Bräuner-Osborne

      Accepted manuscript online: 10 DEC 2016 12:30AM EST | DOI: 10.1111/dom.12845


    1. Effect of race and ethnicity on vildagliptin efficacy: a pooled analysis of phase II and III studies

      P. Kozlovski, M. Fonseca, V. Mohan, V. Lukashevich, M. Odawara, P. M. Paldánius and W. Kothny

      Accepted manuscript online: 10 DEC 2016 12:25AM EST | DOI: 10.1111/dom.12844

    2. Long-term use of dipeptidyl peptidase-4 inhibitors and risk of fracture; a retrospective population-based cohort study

      J.H.M. Driessen, J.P.W. van den Bergh, H.A.W. van Onzenoort, R.M.A. Henry, H.G.M. Leufkens and F. de Vries

      Accepted manuscript online: 10 DEC 2016 12:10AM EST | DOI: 10.1111/dom.12843

    3. Metformin in adults with type 1 diabetes: design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): an international multicentre trial

      J.R. Petrie, N Chaturvedi, I. Ford, I. Hramiak, A.D. Hughes, A.J Jenkins, B. Klein, R. Klein, T.C. Ooi, P. Rossing, N. Sattar, C.D.A Stehouwer and H.M. Colhoun

      Accepted manuscript online: 9 DEC 2016 07:24AM EST | DOI: 10.1111/dom.12840


    1. Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes

      Thomas F. Dejgaard, Nanna B. Johansen, Christian S. Frandsen, Ali Asmar, Lise Tarnow, Filip K. Knop, Sten Madsbad and Henrik U. Andersen

      Accepted manuscript online: 9 DEC 2016 07:21AM EST | DOI: 10.1111/dom.12841



    1. The PDE4 inhibitor roflumilast reduces weight gain by increasing energy expenditure and leads to improved glucose metabolism

      Julia Möllmann, Florian Kahles, Corinna Lebherz, Ben Kappel, Christer Baeck, Frank Tacke, Christian Werner, Massimo Federici, Nikolaus Marx and Michael Lehrke

      Accepted manuscript online: 5 DEC 2016 04:58AM EST | DOI: 10.1111/dom.12839


    1. Exenatide Induces an Increase in Vasodilatory and a Decrease in Vasoconstrictive Mediators

      Ajay Chaudhuri, Husam Ghanim, Antoine Makdissi, Kelly Green, Sanaa Abuaysheh, Manav Batra, Nitesh Kuhadiya and Paresh Dandona

      Accepted manuscript online: 28 NOV 2016 03:55AM EST | DOI: 10.1111/dom.12835

    2. A randomized, double-blind, phase III study to evaluate efficacy and safety of once-daily treatment of alogliptin and metformin hydrochloride in Japanese patients with type 2 diabetes

      Kohei Kaku, Shuuji Sumino, Masafumi Katou, Yuya Nishiyama and Yoshinobu Kinugawa

      Accepted manuscript online: 28 NOV 2016 03:10AM EST | DOI: 10.1111/dom.12837


    1. Novel Hepato-Preferential Basal Insulin Peglispro (BIL) Does Not Differentially Affect Insulin Sensitivity Compared with Insulin Glargine in Patients with Type 1 and Type 2 Diabetes

      Niels Porksen, Helle Linnebjerg, Parag Garhyan, Eric Chen Quin Lam, Mary Pat Knadler, Scott J Jacober, Ulrike Hoevelmann, Leona Plum-Moerschel, Elaine Watkins, Amalia Gastaldelli and Tim Heise

      Accepted manuscript online: 26 NOV 2016 04:15AM EST | DOI: 10.1111/dom.12834

    2. The use of incretin agents and risk of acute and chronic pancreatitis: a population-based cohort study

      Lotte M. Knapen, Roy G.P.J. de Jong, Johanna H.M. Driessen, Yolande C. Keulemans, Nielka P. van Erp, Marie L. De Bruin, Hubert G.M. Leufkens, Sander Croes and Frank de Vries

      Accepted manuscript online: 24 NOV 2016 10:15AM EST | DOI: 10.1111/dom.12833

    3. Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study

      Christian Seerup Frandsen, Thomas Fremming Dejgaard, Henrik Ullits Andersen, Jens Juul Holst, Bolette Hartmann, Birger Thorsteinsson and Sten Madsbad

      Accepted manuscript online: 21 NOV 2016 01:18AM EST | DOI: 10.1111/dom.12830

    4. A Real-world Study of Treatment Patterns and Outcomes in US Managed-Care Patients With Type 2 Diabetes Initiating Injectable Therapies

      W Wei, E Buysman, M Grabner, L Xie, L Brekke, X Ke, JW Chu and PA Levin

      Accepted manuscript online: 17 NOV 2016 01:22AM EST | DOI: 10.1111/dom.12828

    5. Long-term mortality following acute myocardial infarction among those with and without diabetes: A systematic review and meta-analysis of studies in the post reperfusion era

      Nitin N Gholap, Felix A Achana, Melanie J Davies, Kausik K Ray, Laura Gray and Kamlesh Khunti

      Accepted manuscript online: 12 NOV 2016 08:45AM EST | DOI: 10.1111/dom.12827


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