© 2013 The Physiological Society
Edited By: Paul McLoughlin
Impact Factor: 2.79
ISI Journal Citation Reports © Ranking: 2012: 28/80 (Physiology)
Online ISSN: 1469-445X
Associated Title(s): The Journal of Physiology
EP Editor's Choice 2012
All articles are FREE to access
Published online: 11 April 2012
Published by Experimental Physiology
Papers selected by Paul McLoughlin
Since its inception Experimental Physiology has been committed to the publication of leading edge discoveries in integrative physiology addressing mechanistic questions in the whole organism.
Recent advances in genome sequencing, bioinformatics analysis, in vivo genetic manipulation including optogenetics, and advanced imaging technologies have provided powerful new tools with which physiologists can explore these fundamental questions and opens a whole new era in physiological and pathophysiological research.
The papers in this virtual issue have been selected as examples of the integrative and translational research recently published in Experimental Physiology. These papers reflect the enhanced scope of Experimental Physiology which takes on the challenge of publishing research that addresses major questions in physiology by using novel approaches and techniques. A particular additional focus is translational research that seeks to elucidate the role of disturbances of reflex, endocrine and neurohumeral control systems in the development and progression of human diseases and points the way towards how manipulations of these physiological mechanisms could bring therapeutic benefit.
The current editorial board comprises internationally recognized scientists spanning a wide range of expertise positioned to reflect current trends in physiology.
Experimental Physiology has been publishing high-quality physiological research since 1908 and the freely accessible archive contains landmark papers by world-class physiologists providing an important resource to the research community.
This is an exciting time in physiology when we are capitalizing on the major advances made by molecular biology and the resultant techniques to explore fundamental questions in vivo. Experimental Physiology is well placed to communicate these advances to a wide audience.
Angiotensin AT1 receptors in paraventricular nucleus contribute to sympathetic activation and enhanced cardiac sympathetic afferent reflex in renovascular hypertensive rats
Autonomic mechanisms underpinning the stress response in borderline hypertensive rats
Lentivirus-mediated overexpression of angiotensin-(1–7) attenuated ischaemia-induced cardiac pathophysiology
The transcriptome of the medullary area postrema: the thirsty rat, the hungry rat and the hypertensive rats
Effects of graded heat stress on global left ventricular function and twist mechanics at rest and during exercise in healthy humans
Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart
Ageing-dependent remodelling of ion channel and Ca2+ clock genes underlying sino-atrial node pacemaking
Exercise and vascular adaptation in asymptomatic humans
Cardiovascular strain impairs prolonged self-paced exercise in the heat
Spinal opioid receptor-sensitive muscle afferents contribute to the fatigue-induced increase in intracortical inhibition in healthy humans
Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model
Progress in therapy for Duchenne muscular dystrophy
Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to β-hydroxybutyrate
Cholecystokinin and hypothalamic corticotrophin-releasing factor participate in endotoxin-induced hypophagia
Astrocyte chemoreceptors: mechanisms of H+ sensing by astrocytes in the retrotrapezoid nucleus and their possible contribution to respiratory drive
Neuron–glia metabolic coupling and plasticity
Astrocytes as brain interoceptors
A user's guide to channelrhodopsin variants: features, limitations and future developments
Channelrhodopsin as a tool to investigate synaptic transmission and plasticity
Cerebroprotection by angiotensin-(1–7) in endothelin-1-induced ischaemic stroke
Bidirectional control of arteriole diameter by astrocytes