The Journal of Physiology

Cover image for Vol. 593 Issue 22

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: David Paterson

Impact Factor: 5.037

ISI Journal Citation Reports © Ranking: 2014: 5/83 (Physiology); 41/252 (Neurosciences)

Online ISSN: 1469-7793

Associated Title(s): Experimental Physiology


  1. 1 - 75
  1. Cardiovascular

    1. Mechanistically-based mapping of human cardiac fibrillation

      Sanjiv M. Narayan and Junaid A. B. Zaman

      Accepted manuscript online: 26 NOV 2015 04:57AM EST | DOI: 10.1113/JP270513

  2. Neuroscience – cellular/molecular

    1. You have full text access to this OnlineOpen article
      Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells

      Matthew R. Livesey, Dario Magnani, Giles E. Hardingham, Siddharthan Chandran and David J. A. Wyllie

      Accepted manuscript online: 26 NOV 2015 04:57AM EST | DOI: 10.1113/JP270660

  3. Cardiovascular

    1. The mechano-gated channel inhibitor GsMTx4 reduces the exercise pressor reflex in decerebrate rats

      Steven W. Copp, Joyce S. Kim, Victor Ruiz-Velasco and Marc P. Kaufman

      Accepted manuscript online: 26 NOV 2015 04:56AM EST | DOI: 10.1113/JP271714

  4. Molecular and cellular

    1. Calorie restriction as an intervention in ageing

      Guillermo López-Lluch and Plácido Navas

      Accepted manuscript online: 26 NOV 2015 04:56AM EST | DOI: 10.1113/JP270543

    2. The Roles of c-Jun NH2-Terminal Kinases (JNKs) in Obesity and Insulin Resistance

      Martin Pal, Mark A. Febbraio and Graeme I. Lancaster

      Accepted manuscript online: 26 NOV 2015 04:56AM EST | DOI: 10.1113/JP271457

  5. Muscle

    1. Satellite cell response to erythropoietin treatment and endurance training in healthy young men

      Andrea Hoedt, Britt Christensen, Birgitte Nellemann, Ulla Ramer Mikkelsen, Mette Hansen, Peter Schjerling and Jean Farup

      Accepted manuscript online: 26 NOV 2015 04:55AM EST | DOI: 10.1113/JP271333

  6. Neuroscience – development/plasticity/repair

    1. The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome

      Suzanne L Miller, Petra S Huppi and Carina Mallard

      Accepted manuscript online: 26 NOV 2015 04:53AM EST | DOI: 10.1113/JP271402

  7. Integrative

    1. Sway-dependent changes in standing ankle stiffness caused by muscle thixotropy

      Tania E. Sakanaka, Martin Lakie and Raymond F. Reynolds

      Accepted manuscript online: 26 NOV 2015 04:53AM EST | DOI: 10.1113/JP271137

  8. Cardiovascular

    1. Relationship between Retinal Blood Flow and Arterial Oxygen

      Richard W. Cheng, Firdaus Yusof, Edmund Tsui, Monica Jong, James Duffin, John G. Flanagan, Joseph A. Fisher and Chris Hudson

      Accepted manuscript online: 26 NOV 2015 04:53AM EST | DOI: 10.1113/JP271182

  9. Neuroscience – behavioural/systems/cognitive

    1. How environment and self-motion combine in neural representations of space

      Talfan Evans, Andrej Bicanski, Daniel Bush and Neil Burgess

      Accepted manuscript online: 26 NOV 2015 04:52AM EST | DOI: 10.1113/JP270666

  10. Cardiovascular

    1. Sympathetic-Mediated Activation versus Suppression of the Immune System: Consequences for Hypertension

      Adam J. Case and Matthew C. Zimmerman

      Accepted manuscript online: 24 NOV 2015 04:53AM EST | DOI: 10.1113/JP271516

  11. Molecular and cellular

    1. Adaptive responses of cell hydration to a low temperature arrest

      Jens Christmann, Lale Azer, Daniel Dörr, Günter R. Fuhr, Philippe I.H. Bastiaens and Frank Wehner

      Accepted manuscript online: 23 NOV 2015 05:04AM EST | DOI: 10.1113/JP271245

  12. Neuroscience – cellular/molecular

    1. The zebrafish pinball wizard gene encodes WRB, a tail-anchored-protein receptor essential for inner-ear hair cells and retinal photoreceptors

      Shuh-Yow Lin, Melissa A. Vollrath, Sara Mangosing, Jun Shen, Elena Cardenas and David P. Corey

      Accepted manuscript online: 23 NOV 2015 05:03AM EST | DOI: 10.1113/JP271437

  13. Molecular and cellular

    1. Calcium signalling in salivary gland physiology and dysfunction

      Indu S. Ambudkar

      Accepted manuscript online: 23 NOV 2015 05:03AM EST | DOI: 10.1113/JP271143

  14. Alimentary

    1. You have full text access to this OnlineOpen article
      Ageing and gastrointestinal sensory function: Altered colonic mechanosensory and chemosensory function in the aged mouse

      Christopher Keating, Linda Nocchi, Yang Yu, Jemma Donovan and David Grundy

      Accepted manuscript online: 22 NOV 2015 11:04PM EST | DOI: 10.1113/JP271403

  15. Muscle

    1. Myoglobin and the Regulation of Mitochondrial Respiratory Chain Complex IV

      Tatsuya Yamada, Hisashi Takakura, Thomas Jue, Takeshi Hashimoto, Rie Ishizawa, Yasuro Furuichi, Yukio Kato, Nobumasa Iwanaka and Kazumi Masuda

      Accepted manuscript online: 20 NOV 2015 04:18AM EST | DOI: 10.1113/JP270824

  16. Integrative

    1. Effects of acute and chronic systemic methamphetamine on respiratory, cardiovascular and metabolic function, and cardiorespiratory reflexes

      Sarah F Hassan, Travis A Wearne, Jennifer L Cornish and Ann K Goodchild

      Accepted manuscript online: 20 NOV 2015 04:18AM EST | DOI: 10.1113/JP271257

  17. Cardiovascular

    1. Electrical effects of stem cell transplantation for ischaemic cardiomyopathy: Friend or Foe?

      Seth Mount and Darryl R Davis

      Accepted manuscript online: 20 NOV 2015 04:17AM EST | DOI: 10.1113/JP270540

  18. Renal and endocrine

    1. Unilateral renal ischemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased peritubular capillary permeability

      Liliana Monica Bivol, Late Bjarne Magnus Iversen, Michael Hultström, Paal W Wallace, Rolf Kåre Reed, Helge Wiig and Olav Tenstad

      Accepted manuscript online: 20 NOV 2015 04:08AM EST | DOI: 10.1113/JP271578

  19. Integrative

    1. Redox interventions to increase exercise performance

      Michael B. Reid

      Accepted manuscript online: 20 NOV 2015 04:08AM EST | DOI: 10.1113/JP270653

  20. Computational physiology and modelling

    1. Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation

      Jordi Heijman, Pegah Erfanian Abdoust, Niels Voigt, Stanley Nattel and Dobromir Dobrev

      Accepted manuscript online: 19 NOV 2015 04:48AM EST | DOI: 10.1113/JP271404

  21. Cardiovascular

    1. Heterogeneous ageing of skeletal muscle microvascular function

      Judy M. Muller-Delp

      Accepted manuscript online: 17 NOV 2015 08:48AM EST | DOI: 10.1113/JP271005

  22. Neuroscience – behavioural/systems/cognitive

    1. Promoting brain health through exercise and diet in older adults: A physiological perspective

      Philippa A. Jackson, Vincent Pialoux, Dale Corbett, Lauren Drogos, Kirk I. Erickson, Gail A. Eskes and Marc J. Poulin

      Accepted manuscript online: 17 NOV 2015 08:23AM EST | DOI: 10.1113/JP271270

  23. Cardiovascular

    1. Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

      Latt S Mansor, Keshavi Mehta, Dunja Aksentijevic, Carolyn A Carr, Trine Lund, Mark A Cole, Lydia Le Page, Maria da Luz Sousa Fialho, Michael J Shattock, Ellen Aasum, Kieran Clarke, Damian J Tyler and Lisa C Heather

      Accepted manuscript online: 17 NOV 2015 05:16AM EST | DOI: 10.1113/JP271242

    2. Myocardial infarction induces structural and functional remodeling of the intrinsic cardiac nervous system

      Pradeep S. Rajendran, Keijiro Nakamura, Olujimi A. Ajijola, Marmar Vaseghi, J. Andrew Armour, Jeffrey L. Ardell and Kalyanam Shivkumar

      Accepted manuscript online: 17 NOV 2015 04:32AM EST | DOI: 10.1113/JP271165

  24. Muscle

    1. Ca2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans

      C.R. Lamboley, V.L. Wyckelsma, M.J. McKenna, R.M. Murphy and G.D. Lamb

      Accepted manuscript online: 17 NOV 2015 04:27AM EST | DOI: 10.1113/JP271382

  25. Respiratory

    1. Cholinergic control of ventral surface chemoreceptors involves Gq/IP3-mediated inhibition of KCNQ channels

      Cleyton R. Sobrinho, Fu-Shan Kuo, Barbara F. Barna, Thiago S. Moreira and Daniel K. Mulkey

      Accepted manuscript online: 17 NOV 2015 04:23AM EST | DOI: 10.1113/JP271761

  26. Integrative

    1. Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult

      Lesia O. Kurlak, Hiten D. Mistry, Tereza Cindrova-Davies, Graham J. Burton and Fiona Broughton Pipkin

      Accepted manuscript online: 17 NOV 2015 02:12AM EST | DOI: 10.1113/JP271045

  27. Molecular and cellular

    1. Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia

      Mark J. Turner, Vinciane Saint-Criq, Waseema Patel, Salam H. Ibrahim, Bernard Verdon, Christopher Ward, James P. Garnett, Robert Tarran, Martin J. Cann and Michael A. Gray

      Accepted manuscript online: 17 NOV 2015 01:45AM EST | DOI: 10.1113/JP271309

  28. Neuroscience – cellular/molecular

    1. Norepinephrine goes nuclear: Epigenetic modifications during long-lasting synaptic potentiation triggered by activation of beta-adrenergic receptors

      Sabyasachi Maity, Timothy J. Jarome, Jessica Blair, Farah D. Lubin and Peter V. Nguyen

      Accepted manuscript online: 17 NOV 2015 01:36AM EST | DOI: 10.1113/JP271432

    2. Dopamine modulation of transient receptor potential vanilloid type 1 (TRPV1) receptor in dorsal root ganglia neurons

      Saikat Chakraborty, Mario Rebecchi, Martin Kaczocha and Michelino Puopolo

      Accepted manuscript online: 13 NOV 2015 04:11AM EST | DOI: 10.1113/JP271198

  29. Cardiovascular

    1. Stochastic pacing reveals the propensity to cardiac action potential alternans and uncovers its underlying dynamics

      Yann Prudat, Roshni V. Madhvani, Marina Angelini, Nils P. Borgstom, Alan Garfinkel, Hrayr S. Karagueuzian, James N. Weiss, Enno de Lange, Riccardo Olcese and Jan P. Kucera

      Accepted manuscript online: 13 NOV 2015 04:11AM EST | DOI: 10.1113/JP271573

  30. Molecular and cellular

  31. Neuroscience – behavioural/systems/cognitive

  32. Neuroscience – cellular/molecular

  33. Cardiovascular

    1. TRPM4 non-selective cation channels influence action potentials in rabbit Purkinje fibres

      Thomas Hof, Laurent Sallé, Laurent Coulbault, Romain Richer, Joachim Alexandre, René Rouet, Alain Manrique and Romain Guinamard

      Accepted manuscript online: 9 NOV 2015 05:40AM EST | DOI: 10.1113/JP271347

  34. Muscle

    1. Acute resistance exercise activates rapamycin-sensitive and insensitive mechanisms that control translational activity and capacity in skeletal muscle

      Daniel W.D. West, Leslie M. Baehr, George R. Marcotte, Courtney M. Chason, Luis Tolento, Aldrin V. Gomes, Sue C. Bodine and Keith Baar

      Accepted manuscript online: 9 NOV 2015 03:31AM EST | DOI: 10.1113/JP271365

  35. Neuroscience – cellular/molecular

  36. Respiratory

  37. Neuroscience – behavioural/systems/cognitive

    1. The sensory origins of human position sense

      AJ Tsay, MJ Giummarra, TJ Allen and U Proske

      Accepted manuscript online: 5 NOV 2015 04:26AM EST | DOI: 10.1113/JP271498

  38. Cardiovascular

    1. Mitochondrial dynamics, mitophagy and cardiovascular disease

      César Vasquez-Trincado, Ivonne García-Carvajal, Christian Pennanen, Valentina Parra, Joseph A. Hill, Beverly A. Rothermel and Sergio Lavandero

      Accepted manuscript online: 5 NOV 2015 03:40AM EST | DOI: 10.1113/JP271301

    2. Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak

      Rajiv Sankaranarayanan, Yatong Li, David J. Greensmith, David A. Eisner and Luigi Venetucci

      Accepted manuscript online: 5 NOV 2015 03:39AM EST | DOI: 10.1113/JP271473

  39. Neuroscience – cellular/molecular

    1. Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5

      Txomin Lalanne, Julia Oyrer, Adamo Mancino, Erica Gregor, Andrew Chung, Louis Huynh, Sasha Burwell, Jérôme Maheux, Mark Farrant and P. Jesper Sjöström

      Accepted manuscript online: 5 NOV 2015 03:39AM EST | DOI: 10.1113/JP271394

  40. Molecular and cellular

  41. Neuroscience – development/plasticity/repair

    1. Cord blood mononuclear cells prevent neuronal apoptosis in response to perinatal asphyxia in the newborn lamb

      James DS Aridas, Courtney A McDonald, Madison CB Paton, Tamara Yawno, Amy E Sutherland, Ilias Nitsos, Yen Pham, Michael Ditchfield, Michael C Fahey, Flora Wong, Atul Malhotra, Margie Castillo-Melendez, Kishore Bhakoo, Euan M Wallace, Graham Jenkin and Suzanne L Miller

      Accepted manuscript online: 3 NOV 2015 03:26AM EST | DOI: 10.1113/JP271104

  42. Integrative

    1. Plasma hyperosmolality attenuates skin sympathetic nerve activity during passive heat stress in humans

      Daniel Gagnon, Steven A. Romero, Hai Ngo, Paula Y.S. Poh and Craig G. Crandall

      Accepted manuscript online: 3 NOV 2015 03:25AM EST | DOI: 10.1113/JP271497

  43. Cardiovascular

    1. Developmental Aspects of a Life Course Approach to Healthy Ageing

      MA Hanson, C Cooper, A Aihie Sayer, R.J. Eendebak, GF Clough and JR Beard

      Accepted manuscript online: 31 OCT 2015 04:25AM EST | DOI: 10.1113/JP270579

  44. Computational physiology and modelling

    1. In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia

      Pei-Chi Yang, Jonathan D. Moreno, Christina Y. Miyake, Steven B. Vaughn-Behrens, Mao-Tsuen Jeng, Eleonora Grandi, Xander H.T. Wehrens, Sergei Noskov and Colleen E. Clancy

      Accepted manuscript online: 30 OCT 2015 03:59AM EST | DOI: 10.1113/JP271282

  45. Neuroscience – cellular/molecular

    1. Hydrogen peroxide modulates synaptic transmission in ventral horn neurons of the rat spinal cord

      Masayuki Ohashi, Toru Hirano, Kei Watanabe, Keiichi Katsumi, Nobuko Ohashi, Hiroshi Baba, Naoto Endo and Tatsuro Kohno

      Accepted manuscript online: 29 OCT 2015 04:48AM EST | DOI: 10.1113/JP271449

  46. Cardiovascular

    1. Respiratory modulated sympathetic activity: A putative mechanism for developing vascular resistance?

      Linford J.B. Briant, Erin L. O'Callaghan, Alan R. Champneys and Julian F.R. Paton

      Accepted manuscript online: 28 OCT 2015 02:26AM EST | DOI: 10.1113/JP271253

    2. You have full text access to this OnlineOpen article
      Pressure-dependent regulation of Ca2+ signaling in the vascular endothelium

      Calum Wilson, Christopher D. Saunter, John M. Girkin and John G. McCarron

      Accepted manuscript online: 28 OCT 2015 02:26AM EST | DOI: 10.1113/JP271157

  47. Neuroscience – neurobiology of disease

    1. Deficiency of GABAergic synaptic inhibition in the Kölliker-Fuse area underlies respiratory dysrhythmia in a mouse model of Rett syndrome

      Ana Paula Abdala, Marie A. Toward, Mathias Dutschmann, John M. Bissonnette and Julian F.R. Paton

      Accepted manuscript online: 28 OCT 2015 02:26AM EST | DOI: 10.1113/JP270966

    2. Aging-related changes in GABAergic inhibition in mouse auditory cortex, measured using in vitro flavoprotein autofluorescence imaging

      K.A. Stebbings, H.W. Choi, A. Ravindra, D.M. Caspary, J.G. Turner and D.A. Llano

      Accepted manuscript online: 27 OCT 2015 04:21AM EST | DOI: 10.1113/JP271221

  48. Neuroscience – behavioural/systems/cognitive

    1. Corticospinal axons make direct synaptic connections with spinal motoneurons innervating forearm muscles early during postnatal development in the rat

      Hitoshi Maeda, Satoshi Fukuda, Hiroshi Kameda, Naoyuki Murabe, Noriko Isoo, Hiroaki Mizukami, Keiya Ozawa and Masaki Sakurai

      Accepted manuscript online: 27 OCT 2015 04:19AM EST | DOI: 10.1113/JP270885

  49. Cardiovascular

    1. Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

      Thomas A. Jepps, Georgina Carr, Pia R. Lundegaard, Søren-Peter Olesen and Iain A. Greenwood

      Accepted manuscript online: 27 OCT 2015 04:19AM EST | DOI: 10.1113/JP271286

  50. Computational physiology and modelling

  51. Cardiovascular

    1. The role of cyclooxygenase-1 in high salt diet-induced microvascular dysfunction in humans

      Ana Cavka, Anita Cosic, Ivana Jukic, Bojan Jelakovic, Julian H. Lombard, Shane A. Phillips, Vatroslav Seric, Ivan Mihaljevic and Ines Drenjancevic

      Accepted manuscript online: 24 OCT 2015 09:17AM EST | DOI: 10.1113/JP271631

  52. Respiratory

    1. Inhibitory respiratory responses to progesterone and allopregnanolone in newborn rats chronically treated with caffeine

      NagaPraveena Uppari, Vincent Joseph and Aida Bairam

      Accepted manuscript online: 23 OCT 2015 10:54PM EST | DOI: 10.1113/JP270914

  53. Cardiovascular

    1. The fetal brain sparing response to hypoxia: physiological mechanisms

      Dino A Giussani

      Accepted manuscript online: 23 OCT 2015 08:19AM EST | DOI: 10.1113/JP271099

  54. Symposium Review

    1. Proteolytic fragmentation of inositol 1,4,5-trisphosphate Receptors: A novel mechanism regulating channel activity?

      Liwei Wang, Kamil J. Alzayady and David I. Yule

      Accepted manuscript online: 21 OCT 2015 04:52AM EST | DOI: 10.1113/JP271140

  55. Neuroscience – development/plasticity/repair

    1. You have full text access to this OnlineOpen article
      Age-related neuromuscular changes affecting human vastus lateralis

      M. Piasecki, A. Ireland, D. Stashuk, A. Hamilton-Wright, D. A. Jones and J. S. McPhee

      Accepted manuscript online: 21 OCT 2015 04:51AM EST | DOI: 10.1113/JP271087

  56. Molecular and cellular

    1. Essential role of carbonic anhydrase XII in secretory glands fluid and HCO3−Secretion revealed by disease causing human mutation

      Jeong Hee Hong, Emad Muhammad, Changyu Zheng, Eli Hershkovitz, Soliman Alkrinawi, Neta Loewenthal, Ruti Parvari and Shmuel Muallem

      Accepted manuscript online: 21 OCT 2015 04:51AM EST | DOI: 10.1113/JP271378

    2. Gating modes of calcium-activated chloride channels TMEM16A and TMEM16B

      Silvia Cruz-Rangel, José J. De Jesús-Pérez, Juan A. Contreras-Vite, Patricia Pérez-Cornejo, H. Criss Hartzell and Jorge Arreola

      Accepted manuscript online: 21 OCT 2015 04:50AM EST | DOI: 10.1113/JP271256

  57. Muscle

    1. Contractile properties of developing human fetal cardiac muscle

      Alice W. Racca, Jordan M. Klaiman, J. Manuel Pioner, Yuanhua Cheng, Anita E. Beck, Farid Moussavi-Harami, Michael J. Bamshad and Michael Regnier

      Accepted manuscript online: 13 OCT 2015 11:16AM EST | DOI: 10.1113/JP271290

  58. Integrative

    1. Impact of extreme exercise at high altitude on oxidative stress in humans

      John Quindry, Charles Dumke, Dustin Slivka and Brent Ruby

      Accepted manuscript online: 10 OCT 2015 03:44AM EST | DOI: 10.1113/JP270651

  59. Muscle

    1. Innervation and neuromuscular control in ageing skeletal muscle

      Russell T. Hepple and Charles L. Rice

      Accepted manuscript online: 6 OCT 2015 04:17AM EST | DOI: 10.1113/JP270561

  60. Integrative

  61. Muscle

    1. Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle

      J. Whitfield, A. Ludzki, G.J.F. Heigenhauser, J.M.G. Senden, L.B. Verdijk, L.J.C. van Loon, L.L. Spriet and G.P. Holloway

      Accepted manuscript online: 2 OCT 2015 04:07AM EST | DOI: 10.1113/JP270844

  62. Molecular and cellular

  63. Neuroscience – behavioural/systems/cognitive

    1. Use of a physiological profile to document motor impairment in ageing and in clinical groups

      SR Lord, K Delbaere and SC Gandevia

      Accepted manuscript online: 25 SEP 2015 04:20AM EST | DOI: 10.1113/JP271108

  64. Molecular and cellular

    1. Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism – a role for Ca2+?

      Sara Oliveira, Cláudia S. F. Queiroga and Helena L. A. Vieira

      Accepted manuscript online: 17 SEP 2015 05:34AM EST | DOI: 10.1113/JP270955

  65. Muscle

    1. Human skeletal muscle fibre contractile properties and proteomic profile: Adaptations to 3-week unilateral lower limb suspension and active recovery

      Lorenza Brocca, Emanuela Longa, Jessica Cannavino, Olivier Seynnes, Giuseppe de Vito, Jamie McPhee, Marco Narici, Maria Antonietta Pellegrino and Roberto Bottinelli

      Accepted manuscript online: 15 SEP 2015 03:46AM EST | DOI: 10.1113/JP271188


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