The Journal of Physiology

Cover image for Vol. 593 Issue 3

Accepted Articles (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)

Edited By: David Paterson

Impact Factor: 4.544

ISI Journal Citation Reports © Ranking: 2013: 8/81 (Physiology); 55/252 (Neurosciences)

Online ISSN: 1469-7793

Associated Title(s): Experimental Physiology


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  1. Computational physiology and modelling

    1. Effects of lung ventilation-perfusion and muscle metabolism-perfusion heterogeneities on maximal o2 transport and utilization

      I Cano, J Roca and PD Wagner

      Accepted manuscript online: 30 JAN 2015 09:56AM EST | DOI: 10.1113/jphysiol.2014.286492

  2. Cardiovascular

    1. Evidence for a functional vasodilatory role for hydrogen sulfide in the human cutaneous microvasculature

      Jessica L. Kutz, Jody L. Greaney, Lakshmi Santhanam and Lacy M. Alexander

      Accepted manuscript online: 30 JAN 2015 08:58AM EST | DOI: 10.1113/JP270054

  3. Molecular and cellular

    1. Atom-by-atom engineering of voltage-gated ion channels: magnified insights into function and pharmacology

      Stephan A. Pless, Robin Y. Kim, Christopher A. Ahern and Harley T. Kurata

      Accepted manuscript online: 30 JAN 2015 08:58AM EST | DOI: 10.1113/jphysiol.2014.287714

  4. Integrative

    1. Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

      Douglas R. Seals, Jamie N. Justice and Thomas J. LaRocca

      Accepted manuscript online: 29 JAN 2015 08:34AM EST | DOI: 10.1113/jphysiol.2014.282665

  5. Neuroscience – cellular/molecular

    1. Non-signalling energy use in the brain

      Elisabeth Engl and David Attwell

      Accepted manuscript online: 29 JAN 2015 08:34AM EST | DOI: 10.1113/jphysiol.2014.282517

  6. Muscle

    1. Changes in skeletal muscle and tendon structure and function following genetic inactivation of myostatin in rats

      Christopher L Mendias, Evan B Lynch, Jonathan P Gumucio, Michael D Flood, Danielle S Rittman, Douglas W Van Pelt, Stuart M Roche and Carol S Davis

      Accepted manuscript online: 29 JAN 2015 08:34AM EST | DOI: 10.1113/jphysiol.2014.287144

  7. Molecular and cellular

    1. Pannexin 1 Channels Mediate the Release of ATP into the Lumen of the Rat Urinary Bladder

      Jonathan M. Beckel, Stephanie L. Daugherty, Pradeep Tyagi, Amanda S. Wolf-Johnston, Lori A. Birder, Claire H. Mitchell and William C. de Groat

      Accepted manuscript online: 29 JAN 2015 07:23AM EST | DOI: 10.1113/jphysiol.2014.283119

  8. Cardiovascular

    1. The impact of arterial load on left ventricular performance an invasive hemodynamic study in severe mitral stenosis

      Ashwin Venkateshvaran, Srikanth Sola, Satish Chandra Govind, Pravat Kumar Dash, Banajit Barooah, Kambiz Shahgaldi, Anikó Ilona Nagy, Anders Sahlén, Reidar Winter and Aristomenis Manouras

      Accepted manuscript online: 29 JAN 2015 07:23AM EST | DOI: 10.1113/jphysiol.2014.280404

    2. Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness

      Ashley E Walker, Grant D Henson, Kelly D Reihl, R Garrett Morgan, Parker S Dobson, Elizabeth I Nielson, Jing Ling, Robert P Mecham, Dean Y Li, Lisa A Lesniewski and Anthony J Donato

      Accepted manuscript online: 27 JAN 2015 06:37AM EST | DOI: 10.1113/jphysiol.2014.285338

    3. Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: Effect of obesity and ageing

      Anton J.M. Wagenmakers, Juliette A. Strauss, Sam O. Shepherd, Michelle A. Keske and Matthew Cocks

      Accepted manuscript online: 27 JAN 2015 06:36AM EST | DOI: 10.1113/jphysiol.2014.284513

  9. Alimentary

    1. Temporal sequence of activation of cells involved in purinergic neurotransmission in the colon

      Salah A. Baker, Grant W. Hennig, Sean M. Ward and Kenton M. Sanders

      Accepted manuscript online: 27 JAN 2015 06:35AM EST | DOI: 10.1113/jphysiol.2014.287599

  10. Neuroscience – cellular/molecular

    1. Rod electrical coupling is controlled by a circadian clock and dopamine in mouse retina

      Nan Ge Jin, Alice Z. Chuang, Philippe J. Masson and Christophe P. Ribelayga

      Accepted manuscript online: 23 JAN 2015 07:40AM EST | DOI: 10.1113/jphysiol.2014.284919

  11. Cardiovascular

    1. Vascular effects of aerobic exercise training in rat adult offspring exposed to hypoxia-induced intrauterine growth restriction

      Laura M. Reyes, Jude S. Morton, Raven Kirschenman, Darren S. DeLorey and Sandra T. Davidge

      Accepted manuscript online: 23 JAN 2015 07:40AM EST | DOI: 10.1113/jphysiol.2014.288449

  12. Muscle

    1. Increased mitochondrial emission of reactive oxygen species and calpain activation are required for doxorubicin-induced cardiac and skeletal muscle myopathy

      Kisuk Min, Oh-Sung Kwon, Ashley J. Smuder, Michael P. Wiggs, Kurt Sollanek, Demetra D. Christou, Jeung-Ki Yoo, Moon-Hyon Hwang, Hazel H. Szeto, Andreas N. Kavazis and Scott K. Powers

      Accepted manuscript online: 23 JAN 2015 07:40AM EST | DOI: 10.1113/jphysiol.2014.286518

  13. Cardiovascular

    1. Sprint interval and moderate-intensity continuous training have equal benefits on aerobic capacity, insulin sensitivity, muscle capillarisation and endothelial eNOS/NAD(P)Hoxidase protein ratio in obese men

      Matthew Cocks, Christopher S. Shaw, Sam O. Shepherd, James P. Fisher, Aaron Ranasinghe, Thomas A Barker and Anton J.M. Wagenmakers

      Accepted manuscript online: 23 JAN 2015 07:39AM EST | DOI: 10.1113/jphysiol.2014.285254

  14. Neuroscience – cellular/molecular

    1. Inhibitory and excitatory neuromodulation by hydrogen peroxide: Translating energetics to information

      Christian R. Lee, Jyoti C. Patel, Brian O'Neill and Margaret E. Rice

      Accepted manuscript online: 21 JAN 2015 03:16AM EST | DOI: 10.1113/jphysiol.2014.273839

  15. Neuroscience – behavioural/systems/cognitive

    1. Dynamic cortical lateralization during olfactory discrimination learning

      Yaniv Cohen, David Putrino and Donald A. Wilson

      Accepted manuscript online: 21 JAN 2015 03:16AM EST | DOI: 10.1113/jphysiol.2014.288381

    2. You have full text access to this OnlineOpen article
      Nitric oxide selectively suppresses IH currents mediated by HCN1 containing channels

      Cornelia Kopp-Scheinpflug, Beatrice M. Pigott and Ian D. Forsythe

      Accepted manuscript online: 21 JAN 2015 03:16AM EST | DOI: 10.1113/jphysiol.2014.282194

  16. Molecular and cellular

    1. The use of murine-derived fundic organoids in studies of gastric physiology

      Michael A. Schumacher, Eitaro Aihara, Rui Feng, Amy Engevik, Noah F. Shroyer, Karen M. Ottemann, Roger T. Worrell, Marshall H. Montrose, Ramesh A. Shivdasani and Yana Zavros

      Accepted manuscript online: 21 JAN 2015 03:16AM EST | DOI: 10.1113/jphysiol.2014.283028

    2. KCNQ1 channel modulation by KCNE proteins via voltage-sensing domain

      Koichi Nakajo and Yoshihiro Kubo

      Accepted manuscript online: 21 JAN 2015 03:15AM EST | DOI: 10.1113/jphysiol.2014.287672

  17. Respiratory

    1. Molecular underpinnings of ventral surface chemoreceptor function: focus on KCNQ channels

      Daniel K. Mulkey, Virginia E. Hawkins, Joanna M. Hawryluk, Ana C. Takakura, Thiago S. Moreira and Anastasios V. Tzingounis

      Accepted manuscript online: 21 JAN 2015 03:15AM EST | DOI: 10.1113/jphysiol.2014.286500

  18. Integrative

    1. Sensing of triacylglycerol in the gut: Different mechanisms for fatty acids and 2-monoacylglcerol

      Karen Kleberg, Anne Katrine Jacobsen, Jozelia G. Ferreira, Johanne Agerlin Windeløv, Jens F. Rehfeld, Jens Juul Holst, Ivan E. de Araujo and Harald S. Hansen

      Accepted manuscript online: 16 JAN 2015 08:14AM EST | DOI: 10.1113/jphysiol.2014.285635

  19. Molecular and cellular

    1. Discovery of CLC transport proteins: Cloning, structure, function and pathophysiology

      Thomas J. Jentsch

      Accepted manuscript online: 15 JAN 2015 08:16AM EST | DOI: 10.1113/JP270043

  20. Cardiovascular

    1. Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis

      Thomas K. Sin, Bjorn T. Tam, Benjamin Y. Yung, Shea P. Yip, Lawrence W. Chan, Cesar S. Wong, Michael Ying, John A. Rudd and Parco M. Siu

      Accepted manuscript online: 13 JAN 2015 05:26AM EST | DOI: 10.1113/JP270101

  21. Alimentary

    1. Protease-activated receptors modulate excitability of murine colonic smooth muscles by differential effects on interstitial cells

      Tae Sik Sung, Heung Up Kim, Jeong Hwan Kim, Hongli Lu, Kenton M. Sanders and Sang Don Koh

      Accepted manuscript online: 10 JAN 2015 07:16AM EST | DOI: 10.1113/jphysiol.2014.285148

  22. Integrative

    1. Fatigue reduces the complexity of knee extensor torque fluctuations during maximal and submaximal intermittent isometric contractions in man

      Jamie Pethick, Samantha L. Winter and Mark Burnley

      Accepted manuscript online: 10 JAN 2015 01:17AM EST | DOI: 10.1113/jphysiol.2014.284380

  23. Neuroscience – cellular/molecular

  24. Muscle

    1. The role of alterations in mitochondrial dynamics and PGC-1alpha over-expression in fast muscle atrophy following hindlimb unloading

      Jessica Cannavino, Lorenza Brocca, Marco Sandri, Bruno Grassi, Roberto Bottinelli and Maria Antonietta Pellegrino

      Accepted manuscript online: 7 JAN 2015 05:59AM EST | DOI: 10.1113/jphysiol.2014.286740

    2. Slight chronic elevation of C reactive protein is associated with lower aerobic fitness but does not impair meal-induced stimulation of muscle protein metabolism in healthy old men

      Caroline Buffière, François Mariotti, Isabelle Savary-Auzeloux, Carole Migné, Nathalie Meunier, Serge Hercberg, Noel Cano, Didier Rémond, Martine Duclos and Dominique Dardevet

      Accepted manuscript online: 30 DEC 2014 11:48PM EST | DOI: 10.1113/jphysiol.2014.286054

  25. Cardiovascular

    1. Calcium signalling in developing cardiomyocytes: Implications for model systems and disease

      William E. Louch, Jussi T. Koivumäki and Pasi Tavi

      Accepted manuscript online: 30 DEC 2014 11:48PM EST | DOI: 10.1113/jphysiol.2014.274712

  26. Renal and endocrine

    1. You have full text access to this OnlineOpen article
      Large conductance Ca2+-activated K+ channels (BK) promote secretagogue-induced transition from spiking to bursting in murine anterior pituitary corticotrophs

      Peter J. Duncan, Sevgi Sengul, Joel Tabak, Peter Ruth, Richard Bertram and Michael J. Shipston

      Accepted manuscript online: 24 DEC 2014 11:20AM EST | DOI: 10.1113/jphysiol.2014.284471

  27. Computational physiology and modelling

    1. A computational modeling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting late INa

      Pei-Chi Yang, Yejia Song, Wayne R. Giles, Balazs Horvath, Ye-Chen Izu, Luiz Belardinelli, Sridharan Rajamani and Colleen E. Clancy

      Accepted manuscript online: 24 DEC 2014 11:19AM EST | DOI: 10.1113/jphysiol.2014.279554

  28. Muscle

    1. Inward rectifier potassium currents in mammalian skeletal muscle fibers

      Marino DiFranco, Carl Yu, Marbella Quiñonez and Julio L. Vergara

      Accepted manuscript online: 24 DEC 2014 11:19AM EST | DOI: 10.1113/jphysiol.2014.283648

  29. Neuroscience – cellular/molecular

    1. Dorso-ventral differences in Kv7/M-current and its impact on resonance, temporal summation, and excitability in rat hippocampal pyramidal cells

      Christoph Hönigsperger, Máté Marosi, Ricardo Murphy and Johan F. Storm

      Accepted manuscript online: 12 DEC 2014 05:00AM EST | DOI: 10.1113/jphysiol.2014.280826

  30. Research Paper

    1. Consequences of Peripheral Chemoreflex Inhibition with Low-Dose Dopamine in Humans

      Piotr Niewinski, Stanislaw Tubek, Waldemar Banasiak, Julian F.R. Paton and and Piotr Ponikowski

      Accepted manuscript online: 7 JAN 2014 09:44AM EST | DOI: 10.1113/jphysiol.2012.266858

    2. Short-term hypoxic vasodilation in vivo is mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

      Michele Umbrello, Alex Dyson, Bernardo Bollen Pinto, Bernadette O. Fernandez, Verena Simon, Martin Feelisch and Mervyn Singer

      Accepted manuscript online: 3 JAN 2014 06:24AM EST | DOI: 10.1113/jphysiol.2014.255687

    3. Neuronal detection thresholds during vestibular compensation: contributions of response variability and sensory substitution

      Mohsen Jamali, Diana E. Mitchell, Alexis Dale, Jerome Carriot, Soroush G. Sadeghi and Kathleen E. Cullen

      Accepted manuscript online: 3 JAN 2014 06:24AM EST | DOI: 10.1113/jphysiol.2014.267534

    4. Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice

      Helga Vitzthum, Anika Seniuk, Laura Helene Schulte, Maxie Luise Müller, Hannah Hetz and Heimo Ehmke

      Accepted manuscript online: 3 JAN 2014 06:23AM EST | DOI: 10.1113/jphysiol.2014.266924

    5. Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse

      Alessandro Maccione, Matthias H. Hennig, Mauro Gandolfo, Oliver Muthmann, James van Coppenhagen, Stephen J. Eglen, Luca Berdondini and Evelyne Sernagor

      Accepted manuscript online: 3 JAN 2014 06:23AM EST | DOI: 10.1113/jphysiol.2014.262840

    6. Preserved fertility despite erectile dysfunction in mice lacking the NO receptor

      Dieter Groneberg, Barbara Lies, Peter Koenig, Ronald Jäger and Andreas Friebe

      Accepted manuscript online: 6 NOV 2012 08:50PM EST | DOI: 10.1113/jphysiol.2012.24555

    7. Voltage-gated Potassium Channels and the Diversity of Electrical Signaling

      Lily Yeh Jan and Yuh Nung Jan

      Accepted manuscript online: 23 MAR 2012 02:36PM EST | DOI: 10.1113/jphysiol.2011.244212

    8. Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume expanded mice

      Yueh-Chen Lin, Roger H. Adamson, Joyce F. Clark, Rolf K. Reed and Fitz-Roy E. Curry

      Accepted manuscript online: 16 NOV 2011 08:45AM EST | DOI: 10.1113/jphysiol.2011.4866


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