The Journal of Physiology

Cover image for Vol. 592 Issue 18

Edited By: David Paterson

Impact Factor: 4.544

ISI Journal Citation Reports © Ranking: 2013: 8/81 (Physiology); 55/251 (Neurosciences)

Online ISSN: 1469-7793

Associated Title(s): Experimental Physiology

JP Editor's Choice 2012

Online Virtual Issue

JP Editor's Choice 2012

All articles are FREE to access

Published online: 11April 2012

Published by The Journal of Physiology

Papers selected by David Paterson

Table of Contents


Throughout its history The Journal of Physiology has published high-impact opinion leading physiological research. Nobel prize winning discoveries by Adrian, Dale, Huxley, Hodgkin, Katz, Black, Vane, Neher, Sakmann and others have established new fields of research that set the direction of physiology. Our editorial team covers the full range of physiology. We also have the support of some outstanding Consulting Editors, for eg Erwin Neher (Göttingen), Bert Sakmann (Heidelberg), Carol Robinson (Oxford), Roger Tsien (San Diego), Peter Radcliffe (Oxford), and Frances Ashcroft (Oxford) to advise on strategic directions. To emphasise our continuing commitment and desire to publish cutting edge physiology, The Journal of Physiology has a major presence each year at the Experimental Biology in the USA, resulting in special issues. Many big questions remain to be answered in physiology, and at the 2012 meeting, JP will be addressing these questions with our editorial team and the physiological community. This is an exciting time to be in physiology, where significant progress has been made over the last decade in several key technical areas. New discovery in physiology will be facilitated by scientists embracing advances in cell biology, molecular imaging/ fluorescent, genomics, computational physiology/modelling, x ray crystallography and mass spectrometry. Importantly, reassembly of reductive science into in vivo systems is a major challenge that The Journal of Physiology will embrace. We are well positioned to communicate your discoveries.

The papers in this virtual issue have been selected as examples of the broad spectrum of physiology research recently published in JP. For more information about The Journal of Physiology, visit our Information for Authors web page.

Table of Contents



A functional role for the ‘fibroblast-like cells' in gastrointestinal smooth muscles
Masaaki Kurahashi, Haifeng Zheng, Laura Dwyer, Sean M. Ward, Sang Don Koh, and Kenton M. Sanders
 J Physiol 589 (3) 697-710
Suppl Data / F1000


Muscarinic activation of Ca2+-activated Cl− current in interstitial cells of Cajal
Mei Hong Zhu, In Kyung Sung, Haifeng Zheng, Tae Sik Sung, Fiona C Britton, Kate O'Driscoll, Sang Don Koh, and Kenton M. Sanders
 J Physiol 589 (18) 4565-4582



Mitochondrial production of reactive oxygen species contributes to the β-adrenergic stimulation of mouse cardiomycytes
Daniel C. Andersson, Jérémy Fauconnier, Takashi Yamada, Alain Lacampagne, Shi-Jin Zhang, Abram Katz, and Håkan Westerblad
 J Physiol 589 (7) 1791-1801


Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes
E. F. Bode, S. J. Briston, C. L. Overend, S. C. O'Neill, A. W. Trafford, and D. A. Eisner
 J Physiol 589 (19) 4723-4729



Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans
Christopher M. Jung, Edward L. Melanson, Emily J. Frydendall, Leigh Perreault, Robert H. Eckel, and Kenneth P. Wright
 J Physiol 589 (1) 235-244


Central efferent pathways for cold-defensive and febrile shivering
Kazuhiro Nakamura and Shaun F. Morrison
 J Physiol 589 (14) 3641-3658



Infrared photostimulation of the crista ampullaris
Suhrud M. Rajguru, Claus-Peter Richter, Agnella I. Matic, Gay R. Holstein, Stephen M. Highstein, Gregory M. Dittami, and Richard D. Rabbitt
 J Physiol 589 (6) 1283-1294


Intracellular calcium transients evoked by pulsed infrared radiation in neonatal cardiomyocytes
Gregory M. Dittami, Suhrud M. Rajguru, Richard A. Lasher, Robert W. Hitchcock, and Richard D. Rabbitt
 J Physiol 589 (6) 1295-1306
Supplemental data



Modulation of the myogenic response in renal blood flow autoregulation by NO depends on endothelial nitric oxide synthase (eNOS), but not neuronal or inducible NOS
Marcel Dautzenberg, Gerburg Keilhoff, and Armin Just
 J Physiol 589 (19) 4731-4744
Supplemental Data



The temporal relationship between non-respiratory burst activity of expiratory laryngeal motoneurons and phrenic apnoea during stimulation of the superior laryngeal nerve in rat
Qi-Jian Sun, Tara G. Bautista, Robert G. Berkowitz, Wen-Jing Zhao, and Paul M. Pilowsky
 J Physiol 589 (7) 1819-1830



Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans
Benjamin T. Wall, Francis B. Stephens, Dumitru Constantin-Teodosiu, Kanagaraj Marimuthu, Ian A. Macdonald, and Paul L. Greenhaff
 J Physiol 589 (4) 963-973
F1000 Exceptional


The influence of carbohydrate–protein co-ingestion following endurance exercise on myofibrillar and mitochondrial protein synthesis
Leigh Breen, Andrew Philp, Oliver C. Witard, Sarah R. Jackman, Anna Selby, Ken Smith, Keith Baar, and Kevin D. Tipton
 J Physiol 589 (16) 4011-4025


(–)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle
Leonardo Nogueira, Israel Ramirez-Sanchez, Guy A. Perkins, Anne Murphy, Pam R. Taub, Guillermo Ceballos, Francisco J. Villarreal, Michael C. Hogan, and Moh H. Malek
 J Physiol 589 (18) 4615-4631
F1000 Exceptional



High-resolution simultaneous voltage and Ca2+ imaging
Kaspar E. Vogt, Stephan Gerharz, Jeremy Graham, and Marco Canepari
 J Physiol 589 (3) 489-494
Supplemental Data