Journal of Neurochemistry

Cover image for Journal of Neurochemistry

Edited By: Jörg Schulz

Impact Factor: 4.281

ISI Journal Citation Reports © Ranking: 2014: 55/252 (Neurosciences); 72/289 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. Progesterone Receptor Signalling in Retinal Photoreceptor Neuroprotection

    Alice C. Wyse Jackson, Sarah L. Roche, Ashleigh M. Byrne, Ana M. Ruiz-Lopez and Thomas G. Cotter

    Accepted manuscript online: 8 OCT 2015 10:55AM EST | DOI: 10.1111/jnc.13388

  2. Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain

    Imran Imran, Markus H. Hillert and Jochen Klein

    Article first published online: 8 OCT 2015 | DOI: 10.1111/jnc.13360

    Thumbnail image of graphical abstract

    Status epilepticus (SE) was induced in rats by lithium–pilocarpine (‘Pilo’) administration, and extracellular metabolites were measured by microdialysis. Seizures caused several-fold increases in lactate levels which were attenuated by diazepam (‘Diaz’), ketamine, atropine and tetrodotoxin (TTX). Indicators of oxidative stress and membrane damage were also increased during seizures. Omission of calcium and pregabalin, a calcium channel blocker, reduced cellular damage induced by SE.

  3. Sipa1l3/SPAR3 is targeted to postsynaptic specializations and interacts with the Fezzin ProSAPiP1/Lzts3

    Anna Dolnik, Noreen Kanwal, Sarah Mackert, Sonja Halbedl, Christian Proepper, Juergen Bockmann, Michael Schoen, Tobias M Boeckers, Susanne J Kühl and Michael J Schmeisser

    Article first published online: 8 OCT 2015 | DOI: 10.1111/jnc.13353

    Thumbnail image of graphical abstract

    Spine-associated RapGAPs (SPARs) are essential modulators of synaptic signaling. Our study is the first to characterize the SPAR family member Sipa1l3/SPAR3 in neuronal tissue. We show that Sipa1l3/SPAR3 is conserved across species, has a distinct expression pattern in brain and is localized to excitatory postsynapses via its C-terminus, which represents an interaction module for other postsynaptic proteins including the Fezzin ProSAPiP1/Lzts3.

  4. Determination of kainate receptor subunit ratios in mouse brain using novel chimeric protein standards

    Izumi Watanabe-Iida, Kohtarou Konno, Kaori Akashi, Manabu Abe, Rie Natsume, Masahiko Watanabe and Kenji Sakimura

    Accepted manuscript online: 8 OCT 2015 08:53AM EST | DOI: 10.1111/jnc.13384

  5. Direct anti-inflammatory effects of angiotensin-(1-7) on microglia

    Meng Liu, Peng Shi and Colin Sumners

    Accepted manuscript online: 8 OCT 2015 08:52AM EST | DOI: 10.1111/jnc.13386