Journal of Neurochemistry

Cover image for Vol. 141 Issue 3

Edited By: Jörg Schulz

Impact Factor: 3.842

ISI Journal Citation Reports © Ranking: 2015: 71/256 (Neurosciences); 83/289 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function

    Georg Langlhofer and Carmen Villmann

    Accepted manuscript online: 21 APR 2017 03:41AM EST | DOI: 10.1111/jnc.14049

  2. Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice

    Shaowu Cheng, Willayat Y. Wani, David A. Hottman, Angela Jeong, Dongfeng Cao, Kyle J. LeBlanc, Paul Saftig, Jianhua Zhang and Ling Li

    Accepted manuscript online: 21 APR 2017 03:40AM EST | DOI: 10.1111/jnc.14048

  3. “ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate”

    Inés Juaristi, María L. García-Martin, Tiago B Rodrigues, Jorgina Satrústegui, Irene Llorente-Folch and Beatriz Pardo

    Accepted manuscript online: 21 APR 2017 03:40AM EST | DOI: 10.1111/jnc.14047

  4. 60th Anniversary of the Japanese Society for Neurochemistry

    Kazunori Imaizumi

    Version of Record online: 21 APR 2017 | DOI: 10.1111/jnc.13989

    Thumbnail image of graphical abstract

    To welcome the 60th anniversary of the Japanese Society for Neurochemistry, in this issue, we publish five Review articles from the society's leading groups in the Journal of Neurochemistry, and introduce what we have achieved in the neurochemical fields of research, including Ca2+ neurobiology, synaptic plasticity, neurogenesis and neuroregeneration. With the achievements in the past decades in mind, we will continue to contribute to the development of neurochemistry from now on too.

  5. A decrease in eukaryotic elongation factor 2 phosphorylation is required for local translation of sensorin and long-term facilitation in Aplysia

    Patrick K. McCamphill, Larissa Ferguson and Wayne S. Sossin

    Version of Record online: 21 APR 2017 | DOI: 10.1111/jnc.14030

    Thumbnail image of graphical abstract

    Mechanistic target of rapamycin complex 1 (mTORC1)-dependent protein synthesis is required for many forms of synaptic plasticity and memory. We show that the long-term facilitation (LTF)-induced decrease in eukaryotic elongation factor 2 (eEF2) phosphorylation in Aplysia is mediated by S6 kinase-mediated phosphorylation and inactivation of eEF2K. This dephosphorylation is shown to be required for local translation of the neuropeptide sensorin and long-term facilitation in Aplysia sensory-to-motor neuron cultures. This demonstrates the importance of eEF2 dephosphorylation for inducing the synaptic plasticity that underlies memory.

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