Journal of Neurochemistry

Cover image for Vol. 139 Issue S1

Edited By: Jörg Schulz

Impact Factor: 3.842

ISI Journal Citation Reports © Ranking: 2015: 71/256 (Neurosciences); 83/289 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. Rifampicin Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Pathogenic Th17 Cells Responses

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    Accepted manuscript online: 23 OCT 2016 08:05PM EST | DOI: 10.1111/jnc.13871

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  4. You have free access to this content
    Eating disorders: from bench to bedside and back

    Silvana Gaetani, Adele Romano, Gustavo Provensi, Valdo Ricca, Thomas Lutz and Maria Beatrice Passani

    Version of Record online: 21 OCT 2016 | DOI: 10.1111/jnc.13848

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    Our brain and gut are connected by an extensive network of neurons and a highway of chemicals and hormones that affect appetite and energy expenditure, emotions, memory, responses to stress and pain. Clinical and preclinical research is constantly adding new information to the field and orienting studies with the aim of providing a foundation for developing more specific and effective treatment approaches to pathological conditions.

  5. Widespread brain transcriptome alterations underlie the neuroprotective actions of dietary saffron

    Nicholas V. Skladnev, Varshika Ganeshan, Ji Yeon Kim, Thomas J. Burton, John Mitrofanis, Jonathan Stone and Daniel M. Johnstone

    Version of Record online: 21 OCT 2016 | DOI: 10.1111/jnc.13857

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    We confirm previous reports that pre-conditioning by saffron consumption protects the brain of mice against parkinsonian MPTP insult. Intriguingly, 5 days of saffron pre-conditioning provided more robust neuroprotection than 10 days. Investigation of how saffron consumption influences the brain transcriptome revealed molecular changes consistent with neuroprotection as well as the up-regulation of some specific stress-inducible systems. These findings raise the possibility that saffron, like other phytochemicals, may act by inducing an adaptive stress response.