Journal of Neurochemistry

Cover image for Vol. 135 Issue 5

Edited By: Jörg Schulz

Impact Factor: 4.281

ISI Journal Citation Reports © Ranking: 2014: 55/252 (Neurosciences); 72/289 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

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Recently Published Articles

  1. IL-1alpha induces angiogenesis in brain endothelial cells in vitro: implications for brain angiogenesis after acute injury

    Kathleen Salmeron, Takuma Aihara, Elena Redondo-Castro, Emmanuel Pinteaux and Gregory Bix

    Article first published online: 27 NOV 2015 | DOI: 10.1111/jnc.13422

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    Inflammation is a major contributor to neuronal injury and is associated with poor outcome after neurotrauma. We demonstrate that cytokine IL-1α is chronically elevated in the brain after experimental stroke suggesting that it is present chronically post-stroke. We demonstrate that IL-1α is a potent mediator of endothelial activation and inducer of angiogenic markers in endothelial cells. Our data highlights a new role for IL-1 in brain repair mechanisms and identifies IL-1α as a potential therapy to promote post-stroke angiogenesis.

  2. Fast-scan cyclic voltammetry demonstrates that L-DOPA produces dose-dependent regionally selective, bimodal effects on striatal dopamine kinetics in vivo

    R Harun, K M Hare, M E Brough, M J Munoz, C M Grassi, G E Torres, A A Grace and A K Wagner

    Accepted manuscript online: 27 NOV 2015 02:14AM EST | DOI: 10.1111/jnc.13444

  3. Membrane bound tetramer and trimer Aβ oligomeric species correlate with toxicity towards cultured neurons

    Metta K. Jana, Roberto Cappai, Chi L. L. Pham and Giuseppe D. Ciccotosto

    Accepted manuscript online: 26 NOV 2015 02:46AM EST | DOI: 10.1111/jnc.13443

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    Manganese Neurotoxicity: behavioral disorders associated with dysfunctions in the basal ganglia and neurochemical transmission

    Safa Bouabid, Anass Tinakoua, Nouria Lakhdar-Ghazal and Abdelhamid Benazzouz

    Accepted manuscript online: 26 NOV 2015 02:41AM EST | DOI: 10.1111/jnc.13442

  5. Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes

    Tina Baroti, Anja Schillinger, Michael Wegner and C. Claus Stolt

    Article first published online: 25 NOV 2015 | DOI: 10.1111/jnc.13414

    Thumbnail image of graphical abstract

    The transcription factor Sox13 is co-expressed with the related Sox5 and Sox6 in cells of the oligodendroglial lineage. By itself, it has little impact on oligodendrocyte development but supports Sox5 and Sox6 during the process as a functionally redundant transcription factor.