Journal of Neurochemistry

Kiichiro Okano, Akiko Maeda, Yu Chen, Vishal Chauhan, Johnny Tang, Grazyna Palczewska, Tsutomu Sakai, Hiroshi Tsuneoka, Krzysztof Palczewski and Tadao Maeda

Article first published online: 9 FEB 2012 | DOI: 10.1111/j.1471-4159.2012.07647.x

Rods are more susceptible than cones to light-induced damage: implications for human macular diseases We asked whether rods or cones are more susceptible to light-induced, all-trans-retinal-dependent damage and how any difference of susceptibility could affect the pathology of human macular diseases. Rods are more susceptible than cones to light-induced cell death; similar pathological changes were observed in patients with human macular disease. This finding can partially explain initial pathological events of human macular diseases and add to our understanding of these pathologies.

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Tet Woo Lee, Johanna M. Montgomery and Nigel P. Birch

Article first published online: 9 FEB 2012 | DOI: 10.1111/j.1471-4159.2011.07639.x

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Apostolia Fragkouli, Costas Papatheodoropoulos, Spiros Georgopoulos, Antonios Stamatakis, Fotini Stylianopoulou, Effie C. Tsilibary and Athina K. Tzinia

Article first published online: 9 FEB 2012 | DOI: 10.1111/j.1471-4159.2011.07637.x

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