Journal of Neurochemistry

Cover image for Vol. 125 Issue 4

Edited By: Jörg Schulz

Impact Factor: 4.061

ISI Journal Citation Reports © Ranking: 2011: 59/244 (Neurosciences); 77/290 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

Editorial Board



Chief Editor & Editorial Office | Deputy Chief Editors | Deputy Chief Editor Reviews | Handling Editors | ISN Publication Committee

Chief Editor & Editorial Office

Jörg B. Schulz, Aachen, Germany (JNC-CE@ukaachen.de)
Laura Hausmann, Aachen, Germany (Lhausmann@ukaachen.de)
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Deputy Chief Editors

Steven Barger, Little Rock, AK, USA (bargerstevenw@uams.edu) – Gene Regulation & Genetics
Hiroyuki Nawa, Niigata, Japan (hnawa@bri.niigata-u.ac.jp) - Signal Transduction & Synaptic Transmission
Gennadij Raivich, London, UK (g.raivich@ucl.ac.uk) - Development & Cell Biology
Xiongwei Zhu, Cleveland, OH, USA (xiongwei.zhu@case.edu) - Bioenergetics & Metabolism
Tammy Kielian, Omaha, NE, USA (tkielian@unmc.edu) - Neuroinflammation & Neuroimmunology
Min Zhuo, Toronto, Canada (min.zhuo@utoronto.ca) - Neuronal Plasticity & Behavior
Roberto Cappai, Melbourne, Australia (r.cappai@unimelb.edu.au) - Molecular Basis of Disease
David H. Small, Hobart, Australia (d.h.small@menzies.utas.edu.au) - Molecular Basis of Disease
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Deputy Chief Editor Reviews

Marcus Rattray, Bradford, UK (m.rattray@bradford.ac.uk)
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Handling Editors

Jan Albrecht, Warsaw, Poland (jalbrecht@imdik.pan.pl)
Christian Behl, Mainz, Germany (cbehl@uni-mainz.de)
Juan P. Bolanos, Salamanca, Spain (jbolanos@aida.usal.es)
Piotr Bregestovski, Marseille, France (piotr.bregestovski@univmed.fr)
Susan Browne, West Point, PA, USA (Susan_browne@merck.com)
Andrés Buonanno, Bethesda, USA (buonanno@mail.nih.gov)
Martin Cammarota, Natal, Brazil (mcammaro@terra.com.br)
Rudolph Castellani, Baltimore, ML, USA (rcastellani@som.umaryland.edu)
Bill Piu Chan, Beijing, China (pbchan90@gmail.com)
Amitabha Chattopadhyay, Hyderabad, India (amit@ccmb.res.in)
Janet Clark, Philadelphia, PA, USA (jclark@drexelmed.edu)
James R. Connor, Hershey, PA, USA (jconnor@hmc.psu.edu)
Mark R. Cookson, Bethesda, MD, USA (cookson@mail.nih.gov)
Martin Dichgans, Munich, Germany ( mdichgans@nefo.med.uni-muenchen.de)
Alexander Dityatev, Genoa, Italy (alexander.dityatev@iit.it)
Douglas L. Feinstein, Chicago, IL, USA (dlfeins@uic.edu)
Sergio T. Ferreira, Rio de Janeiro, Brazil (ferreira@bioqmed.ufrj.br)
Babette Fuss, Richmond, VA, USA (bfuss@hsc.vcu.edu)
Christian Giaume, Paris, France (christian.giaume@college-de-France.fr)
Paul E. Gottschall, Little Rock, AR, USA (pegottschall@uams.edu)
Natalia V. Gulyaeva, Moscow, Russia (nata_gul@pisem.net)
Eckart D. Gundelfinger, Magdeburg, Germany (gundelfinger@ifn-magdeburg.de)
John Hardy, London, UK (j.hardy@ion.ucl.ac.uk)
Teresa G. Hastings, Pittsburgh, PA, USA (hastings@bns.pitt.edu)
Michael Heneka, Bonn, Germany (michael.heneka@ukb.uni-bonn.de)
Etienne Hirsch, Paris, France (etienne.hirsch@upmc.fr)
William (Roberto) Invernizzi, Milan, Italy (rinvernizzi@marionegri.it)
Philipp Kahle, Tübingen, Germany (Philipp.Kahle@uni-tuebingen.de)
Paul J. Kenny, Jupiter, FL, USA (pjkenny@scripps.edu)
Kyong-Tai Kim, Pohang, Korea (ktk@postech.ac.kr)
Mark Kindy, Charleston, SC, USA (kindyms@musc.edu)
Hiroshi Kiyama, Nagoya, Japan (kiyama@med.nagoya-u.ac.jp)
Michael Koch, Bremen, Germany (Michael.koch@uni-bremen.de)
Michael Lee, Minneapolis, MN, USA (mklee@umn.edu)
Marcel Leist, Konstanz, Germany (marcel.leist@uni-konstanz.de)
Vilma R. Martins, Sao Paulo, Brazil (vmartins@cipe.accamargo.org.br)
Mary C. McKenna, Baltimore, MD, USA (mmckenna@umaryland.edu)
Kevin St. P. McNaught, New York, NY, USA (kevin.mcnaught@mssm.edu)
Frederic A. Meunier, Brisbane, Australia (f.meunier@uq.edu.au)
Elek Molnár, Bristol, UK (Elek.Molnar@bristol.ac.uk)
Anne N. Murphy, La Jolla, CA, USA (anmurphy@cox.net)
Eric J. Murphy, Grand Forks, ND, USA (emurphy@medicine.nodak.edu)
Akihiko Nunomura, Yamanashi, Japan (anunomura@yamanashi.ac.jp)
Jean-Noël Octave, Brussels, Belgium (octave@nchm.ucl.ac.be)
Arturo Ortega, Mexico City, Mexico (arortega@cinvestav.mx)
David S. Park, Ottawa, Canada (dpark@uottawa.ca)
Maria Passafaro, Milan, Italy (m.passafaro@in.cnr.it)
Marina Picciotto, New Haven, USA (marina.picciotto@yale.edu)
Peter Penzes, Chicago, IL, USA (p-penzes@northwestern.edu)
Marco A. M. Prado, London, ON, Canada (maximo.prado@gmail.com)
Alessandro Prinetti, Milan, Italy (alessandro.prinetti@unimi.it)
Elena A. Rybnikova, St.Petersburg, Russia (samoilov@pavlov.infran.ru, rybnikova1@rambler.ru)
Ester L. Sabban, Valhalla, NY, USA (esther_sabban@nymc.edu)
Carlo Sala, Milan, Italy (c.sala@in.cnr.it)
Michael F. Salvatore, Shreveport, LA, USA (msalva@lsuhsc.edu)
Ana M. Sebastião, Lisbon, Portugal (anaseb@fm.ul.pt)
Frank R. Sharp, Sacramento, CA, USA (frank.sharp@ucdmc.ucdavis.edu)
Tomoaki Shirao, Gunma, Japan (tshirao@med.gunma-u.ac.jp)
Weihong Song, Vancouver, Canada (weihong@exchange.ubc.ca)
Maria de Souza Silva, Duesseldorf, Germany (desouza@uni-duesseldorf.de)
David G. Standaert, Birmingham, AL, USA (dstandaert@uab.edu)
Jörg Stehle, Frankfurt, Germany (stehle@em.uni-frankfurt.de)
Tetsuya Terasaki, Sendai, Japan (terasaki@mail.pharm.tohoku.ac.jp)
Roxanne A. Vaughan, Grand Forks, ND, USA (rvaughan@medicine.nodak.edu)
Jose L. Venero, Seville, Spain (jlvenero@us.es)
Bryce Vissel, Sydney, Australia (b.vissel@garvan.org.au)
Helle S. Waagepetersen, Copenhagen, Denmark (hsw@farma.ku.dk)
Michael Weller, Zurich, Switzerland (michael.weller@usz.ch)
Wolfgang Wick, Heidelberg, Germany (wolfgang.wick@med.uni-heidelberg.de)
Stephen R. Williams, Manchester, UK (steve.williams@manchester.ac.uk)
Marina E. Wolf, North Chicago, IL, USA (marina.wolf@rosalindfranklin.edu)
Yung H. Wong, Hong Kong, China (boyung@ust.hk)
Ian C. Wood, Leeds, UK (i.c.wood@leeds.ac.uk)
Bryan Yamamoto, Toledo, OH, USA (Bryan.Yamamoto@utoledo.edu)
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International Society for Neurochemistry Publications Committee

A. J. Turner, Leeds, Chair

M. J. Carson, Riverside, ISN Secretary
K. Ikenaka, Okazaki, ISN Treasurer
M. A. Rattray, Bradford, Deputy Chief Editor (Reviews)
A. Saria, Innsbruck, ISN President
J. B. Schulz, Aachen, Chief Editor
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Editors and their specialist fields:
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Jörg B. SchulzJörg B. Schulz

Chief Editor
Professor of Neurology and Chair, Department of Neurology, University Hospital, RWTH Aachen, Pauwelsstrasse 30, D-52074 Aachen, Germany

Phone: 49 241 808 9600 Fax: 49 241 808 2582
Email: JNC-CE@ukaachen.de

Keywords: Alzheimer's disease, apoptosis, cell death, clinical studies, gene therapy, motor neuron disorders, neuroprotection, Parkinson's disease, protein aggregation, synuclein, trinucleotide disorders

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Laura HausmannLaura Hausmann

Managing Editor
Department of Neurology, University Hospital, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany

Tel: 49 241 80 89920
Email: Lhausmann@ukaachen.de

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Steven BargerSteven Barger

Deputy Chief Editor - Gene Regulation & Genetics
University of Arkansas Medical School, Little Rock, AK, USA
Email: bargerstevenw@uams.edu

Keywords: Alzheimer's disease, aging, multi-lineage kinases, cytokines, cyclic nucleotides, proteins, calcium-binding, calcium regulation, glutamate receptors, neuroinflammation, transcriptional regulation, microglia

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Hiroyuki NawaHiroyuki Nawa

Deputy Chief Editor - Signal Transduction & Synaptic Transmission
Niigata University, Niigata, Japan
Email: hnawa@bri.niigata-u.ac.jp
Web URL: http://www.bri.niigata-u.ac.jp/

Keywords: cellular neurobiology or brain disease, cytokine, neurotrophic factor, development schizophrenia, dopamine, behavior

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Gennadij RaivichGennadij Raivich

Deputy Chief Editor - Development & Cell Biology
University College London, London, UK
Email: g.raivich@ucl.ac.uk

Keywords: neurotrophins, colony stimulating factors, transcription factors, axonal injury and regeneration, microglia and phagocytes, neuroinflammation, hypoxic ischemic insult

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Xiongwei Zhu

Deputy Chief Editor - Bioenergetics & Metabolism
Case Western Reserve University, Cleveland, OH, USA
Email: xiongwei.zhu@case.edu

Keywords: Alzheimer disease, Amyotrophic Lateral Sclerosis (ALS), apoptosis, cell cycle, Huntington disease, metal ion, mitochondria, neurodegenerative diseases, neurodegeneration, oxidative stress, Parkinson disease, Signal Transduction

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Tammy KielianTammy Kielian

Deputy Chief Editor - Neuroinflammation & Neuroimmunology
University of Nebraska Medical Center, Omaha, Nebraska, USA
Email: tkielian@unmc.edu

Keywords: chemokines, neuroimmunology, gap junctions, experimental brain abscess, astrocytes, microglia, cytokines

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Min ZhuoMin Zhuo

Deputy Chief Editor - Neuronal Plasticity & Behavior
University of Toronto, Toronto, ON, Canada
Email: min.zhuo@utoronto.ca
Phone: 417-978-4018 Fax: 416-978-4940

Keywords: adenylyl cyclase, AMPA receptors, behaviour, Calcium, calmodulin-dependent protein kinase, GABA, glutamate, kainate, learning, memory, molecular biology, NMDA receptor NR2B, nociception, pain, plasminogen activator receptor LRP

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Roberto CappaiRoberto Cappai

Deputy Chief Editor - Molecular Basis of Disease
The University of Melbourne, Victoria, Australia
Email: r.cappai@unimelb.edu.au
Web URL: http://www.unimelb.edu.au/

Keywords: Alzheimer's disease, amyloid, amyloid precursor protein, Creutzfeldt-Jakob disease, prion, synuclein, Parkinson's disease, neurodegeneration, copper

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David H. Small

Deputy Chief Editor - Molecular Basis of Disease
Menzies Research Institute, Private Bag 23, Hobart, TAS 7001, Australia

Email: d.h.small@menzies.utas.edu.au
Web URL: http://www.menzies.utas.edu.au/information.php?Doo=ViewData&type=Person&ID=119

Keywords: Alzheimer's disease, amyloid precursor protein, acetylcholinesterase, butyrylcholinesterase, enzymology, molecular modelling, neurite outgrowth, ion channels, amyloid, neurodegeneration, protein misfolding

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Marcus RattrayMarcus Rattray

Deputy Chief Editor - Reviews
University of Bradford, School of Life Sciences, Bradford, BD7 1DP, UK

Email: m.rattray@bradford.ac.uk

Keywords: neurotransmitter transporters; drug abuse, 5-HT (serotonin); gene expression; motor neurone disease; astrocytes; neurodegeneration
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Handling Editors

Jan AlbrechtJan Albrecht

Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
Email: jalbrecht@imdik.pan.pl

Keywords: amino acids, ammonia, astrocytes, blood brain barrier, excitotoxicity, glia, gliotransmission, glutamine, glutathione, neuron-glia interaction, neurotoxicity, neurotoxicology, neurotransmitters, neurotransmitter transporters, neurotransmitter receptors, oxidative and nitrosative stress

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Christian Behl

Johannes Gutenberg University Mainz, Germany
Phone: 49 6131 3925890 Fax: 49 6131 3925792
Email: cbehl@uni-mainz.de

Keywords: Alzheimer's disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis (ALS), pathobiochemistry, stroke, molecular biology, cell biology, neurodegeneration, neuroprotection, cell death, apoptosis, necrosis, aging, amyloid, glutamate, free radical species, oxidative stress, protein homeostasis, animal model systems (C. elegans, mouse, rat)

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Juan P. BolanosJuan P. Bolanos

University of Salamanca, Salamanca, Spain
Email: jbolanos@aida.usal.es
Web URL: http://web.usal.es/~jbolanos/

Keywords: Oxidative stress, Mitochondrial bioenergetics, Glutathione, Parkinson's disease, Regulation of glycolysis, Cell cycle and neurodegeneration, Nitric oxide, Peroxynitrite, Neuronal-glial metabolic interactions, Neurotoxicity signalling, Neuroprotective signalling, AMP-activated protein kinase (AMPK) signalling

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Piotr BregestovskiPiotr Bregestovski

Mediterranean Institute of Neurobiology (INMED), Marseille, France
Email: piotr.bregestovski@univmed.fr

Keywords: Function, modulation and structure of receptor-operated channels, cys-loop receptors; GABA- and glycinergic synapses; electrophysiological and image analysis of synaptic transmission; chloride monitoring; imaging of neuronal networks; endocannabinoids in modulation of synaptic function; patch-clamp and image analysis of retina.

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Susan Browne

Merck Research Laboratories, West Point, PA, USA
Email: Susan_browne@merck.com

Keywords: animal models of neurodegenerative diseases, stroke, Huntington's disease, Amyotrophic Lateral Sclerosis (ALS), Parkinson's disease

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Andrés Buonanno

National Institute of Health, Bethesda, USA
Email: buonanno@mail.nih.gov

Keywords: ErbB signaling, neuregulin, neuronal networks, psychiatric disorders

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Martin Cammarota

Brain Institute, Federal University of Rio Grande do Norte (UFRN), Natal, Brazil
Email: mcammaro@terra.com.br

Keywords: AMPA receptors, acetylcholine (ACh), angiotensin, behavior, brain-derived neurotrophic factor (BDNF), Calcium/calmodulin-dependent protin kinase II (CaMKII), cannabinoids, dopamine, glutamate, histamine, learning, MAPK, memory consolidation, NMDA receptors, noradrenaline, protein kinases (PKA, PKC), psychopharmacology, synaptic plasticity, tyrosine kinases

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Rudolph CastellaniRudolph Castellani

University of Maryland School of Medicine, Baltimore, ML, USA
Email: rcastellani@som.umaryland.edu

Keywords: Alzheimer's disease, prion diseases, Creutzfeldt-Jakob disease, PrPsc molecules, molecular genetics, oxidative stress

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Bill Piu ChanPiu Bill Chan

Xunanwu Hospital, Beijing, China
Email: pbchan90@gmail.com

Keywords: neurodegeneration, neurotoxicity, molecular genetics, Parkinson's disease and other movement disorders

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Amitabha ChattopadhyayAmitabhaChattopadhyay

Centre for Cellular and Molecular Biology, Hyderabad, India
Email: amit@ccmb.res.in

Keywords: G-protein coupled receptor (GPCR); Membrane lipid-receptor interaction; Fluorescence spectroscopy; FRAP; FCS; Membrane cholesterol; Neuronal membrane; Membrane domain

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Janet ClarkJanet Clark

Drexel University College of Medicine, Philadelphia, PA, USA
Phone: 1 215 762 8578 Fax: 1 215 762 2299
Email: jclark@drexelmed.edu
Web URL: http://www.linkedin.com/in/janeteaclark

Keywords: neurotransmitter transporters, neuroendocrinology, hormones, estrogen, glucocorticoid effects, psychiatric diseases, depression, stress, neuropharmacology, tryptophan hydroxylase (TPH), GABAB receptors, cytokines, indoleamine-2,3-dioxygenase, microglia, human platelet antigen (HPA), molecular biology, cloning, protein biochemistry

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James R. ConnorJames Connor

Penn State University, Hershey, Pennsylvania, USA
Email: jconnor@hmc.psu.edu

Keywords: Metals in the brain, Neurodegenerative diseases, Blood-brain-barrier, CSF, Biomarkers, Glia, Myelin

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Mark R. CooksonMark Cookson

Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA
Email: cookson@mail.nih.gov

Keywords: Parkinson's disease, genetics, cell biology, kinases, oxidative stress, gene expression

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Martin Dichgans

Clinic of the Munich University, Munich, Germany
Email: mdichgans@nefo.med.uni-muenchen.de

Keywords: cerebrovascular system, microvascular system, stroke, vascular cognitive impairment

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Alexander DityatevAlexander Dityatev

Italian Institute of Technology, Genoa, Italy
Email: alexander.dityatev@iit.it

Keywords: in vitro and in vivo neurophysiology, immunocyto- and histochemistry, and cognitive behavioral tests, with emphasis on fear conditioning, cell adhesion, extracellular matrix, synaptic plasticity, LTP, LTD, metaplasticity, GABAergic and glutamatergic synaptic transmission, synaptogenesis

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Douglas L. FeinsteinDouglas L. Feinstein

University of Illinois at Chicago, Chicago, IL, USA
Email: dlfeins@uic.edu

Keywords: glial cells, nitric oxide, cell signalling, cytokines, inflammation, astrocyte, astroglia, glioma, microglia, nitric oxide, endotoxin, LPS, GFAP, heat shock, HSP, MAPK (mitogen activated protein kinases), arginine, cytokines, EAE, MS, CAMP, astrocyte, nitric oxide, cytokines, TgAPP, EAE, multiple sclerosis, Alzheimer's disease, PPAR, NFkB, microgila

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Sergio T. FerreiraSergio T. Ferreira

Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Email: ferreira@bioqmed.ufrj.br
Tel: ( 5521)2562-6790 (off) or ( 5521)3888-8308 (lab) Fax: ( 5521)2270-8647

Keywords: AMPA receptors, Alzheimer’s disease, Abeta oligomers, amyloid, behavioral testing, glutamatergic neurotransmission, neurodegeneration, neuronal insulin signaling, NMDA receptors, memory, synapses

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Babette Fuss

Virginia Commonwealth University, Medical College of Virginia, VA, USA
Email: bfuss@hsc.vcu.edu

Keywords: Extracellular matrix, Transgenic mice, Oligodendrocyte, Multiple sclerosis, Focal adhesion, Myelination, Myelin

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Christian GiaumeChristian Giaume

INSERM U840, Collège de France, Paris, France
Email: christian.giaume@college-de-France.fr

Keywords: Neuroglial interaction, gap junctions, astrocytes, microglia, reactive gliosis, calcium signaling, glial electrophysiology

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Paul E. GottschallPaul E. Gottschall

University of Arkansas for Medical Sciences, Little Rock, AR, USA
Email: pegottschall@uams.edu

Keywords: proteoglycans, extracellular matrix, matrix metalloproteinases, proteases, neural plasticity, synaptic plasticity, neuroinflammation, Alzheimer’s disease, vaccination, cerebral palsy, hypoxia-ischemia

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Natalia V. GulyaevaNatalia V. Gulyaeva

Institute of Higher Nervous Activity and Neurophysiology, Moscow, Russia
Email: nata_gul@pisem.net

Keywords: neuronal cell death, apoptosis, neurodegeneration, excitotoxicity, neuroprotection, neurogenesis, neurodegenerative diseases –animal and cellular models, mechanisms, biomarkers, glia in neurodegeneration, cerebral ischemia, stroke, neuroinflammation, proteases, caspases, cathepsins, free radicals, oxidative stress, neuronal(synaptic) plasticity – molecular mechanisms and behavior, nitric oxide, epilepsy, Alzheimer's disease, amyloid beta toxicity, neuropeptides, stress-induced pathology

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Eckart D. GundelfingerEckart Gundelfinger

Federal Institute for Neurobiology, Magdeburg, Germany
Email: gundelfinger@ifn-magdeburg.de

Keywords: synapse, synaptic proteins, neurotransmitter receptors, molecular biology of neurotransmitter release, neuronal cytoskeleton, calcium-binding proteins, DNA cloning, molecular biology of protein-protein interaction.

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John HardyJohn Hardy

Department of Molecular Neuroscience and Reta Lilla Weston Laboratories, Institute of Neurology, London, UK
Email: j.hardy@ion.ucl.ac.uk

Keywords: genetics, neurodegeneration, Alzheimer, Parkinson

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Teresa G. Hastings

University of Pittsburgh, Pittsburgh, PA, USA
Email: hastings@bns.pitt.edu

Keywords: proteomics, 2D-DIGE, mitochondria, PC12, dopamine, endoplasmic reticulum stress

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Michael HenekaMichael Heneka

University of Bonn, Bonn, Germany
Email: michael.heneka@ukb.uni-bonn.de

Keywords: Neurodegeneration, neuroinflammation, nuclear hormone receptor biology, nitric oxide

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Etienne HirschEtienne Hirsch

INSERM UMR679, Hôpital de la Salpêtrière, Paris, France
Email: etienne.hirsch@upmc.fr

Keywords: Cell death, neurodegenerative disorders, Parkinson's disease, Alzheimer's disease, molecular and cellular biology, histology, animal studies.

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William (Roberto) InvernizziWilliam (Roberto) Invernizzi

Mario Negri Institute of Pharmacological Research (Istituto di Ricerche Farmacologiche "Mario Negri"), Milan, Italy
Email: rinvernizzi@marionegri.it
Phone: 39 02 390141Fax: 39 02 3546277

Keywords: antidepressants, antipsychotics, serotonin, in vivo microdialysis, neurotransmitter release, dopamine, noradrenaline

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Philipp Kahle

Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University of Tübingen, Tübingen, Germany
Email: Philipp.Kahle@uni-tuebingen.de
Web URL: http://www.hih-tuebingen.de/funct-neurogenet/
Phone: ( 49-7071) 29-81970 / -81968 (lab) / -82039 (secr) Fax: ( 49-7071) 29-4620

Keywords: DJ-1, frontotemporal dementia, functional neurogenetics, FUS protein, leucine-rich repeat kinase, Parkinson's disease, parkin, synuclein, TDP-43

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Paul J. KennyPaul J. Kenny

The Scripps Research Institute, Laboratory of Behavioral and Molecular Neuroscience, Jupiter, FL, USA
Email: pjkenny@scripps.edu

Keywords: addiction, behavior, kinases, microRNA, nicotine, nicotinic acetylcholine receptors, noncoding RNAs, obesity, orexin/hypocretin, schizophrenia

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Kyong-Tai KimKyong-Tai Kim

Pohang University of Science and Technology (POSTECH), Pohang, Korea
Email: ktk@postech.ac.kr

Keywords: receptor signaling, exocytosis, regulation of circadian genes, posttranscriptional regulation, regulation of melatonin biosynthesis

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Mark KindyMark Kindy

Medical University of South Carolina, Charleston, SC, USA
Email: kindyms@musc.edu
Phone: 843-792-0559Fax: 843-876-5099

Keywords: Alzheimer's disease, Parkinson’s disease, stroke, traumatic brain injury, spinal cord injury, neurodegeneration, Abeta, APoE, tau, toxins, biochemistry, behaviour, receptor for advanced glycation endproducts (RAGE), Neprilysin

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Hiroshi KiyamaHiroshi Kiyama

Nagoya University Graduate School of Medicine, Nagoya, Japan
Phone: 81-52744-2015
Email: kiyama@med.nagoya-u.ac.jp

Keywords: neuronal regeneration, mechanisms underlying neuronal cell death and survival after nerve injury, neurite elongation after nerve injury, nerve regeneration events

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Michael KochMichael Koch

University of Bremen, Center for Cognitive Sciences, Bremen, Germany
Email: Michael.koch@uni-bremen.de
Phone: 49 421 218 62970 Fax: 49 421 218 62984

Keywords: behavioral pharmacology, animal models of neurological and psychiatric diseases, drugs of abuse, fear, anxiety, schizophrenia, neurodevelopment, neurotoxicology

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Michael Lee

University of Minnesota, Twin Cities, Minneapolis, MN, USA
Email: mklee@umn.edu

Keywords: Parkinson's disease, Alzheimer's disease, neurodegeneration, synuclein, protein aggregation, transgenic mice

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Marcel LeistMarcel Leist

University of Konstanz, Konstanz, Germany
Email: marcel.leist@uni-konstanz.de
Web URL: http://www.uni-konstanz.de/

Keywords: neural stem cells, microglia activation, astrocyte activation, glia in neurodegeneration, Mixed-lineage kinase, amyloid-beta processing, amyloid beta toxicity, Parkinson's disease models, neurite degeneration, dopamine storage

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Vilma R. MartinsVilma R. Martins

Hospital A.C. Camargo, Sao Paulo, Brazil
Email: vmartins@cipe.accamargo.org.br

Keywords: Prion, Cellular prion protein, Neuronal survival, Development, Heat shock proteins

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Mary C. McKennaMary C. McKenna

University of Maryland School of Medicine, Baltimore, MD, USA
Email: mmckenna@umaryland.edu

Keywords: energy metabolism, glutamate metabolism, lactate metabolism, perinatal brain injury, 1H and 13C-NMR spectroscopy, Fragile X syndrome, mitochondrial transporters, synaptosomal metabolism, astrocyte metabolism, malate-aspartate shuttle, glutamine, MCT1, MCT2, mitochondrial enzymes, traumatic brain injury to developing brain, perinatal hypoxia ischemia, intrauterine inflammation

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Kevin St. P. McNaught

Mount Sinai School of Medicine, New York, NY, USA
Email: kevin.mcnaught@mssm.edu

Keywords: alpha-synuclein, dystonia, animal models, Parkinson's disease, parkin, proteasome, ubiquitin, torsinAl

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Frederic A. MeunierFrederic A. Meunier

The University of Queensland, Brisbane, QLD, Australia
Email: f.meunier@uq.edu.au
Web URL: http://www.qbi.uq.edu.au/group-leader-meunier

Keywords: Neuroexocytosis, neurotransmitter release, synaptic vesicles, neurosecretory vesicles, calcium channels, synaptotagmin, SNARE proteins, Munc18-1, fatty acids, phosphoinositides, pre-synaptic trafficking, neurotoxins, clostridial toxins, marine toxins

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Elek MolnárElek Molnár

University of Bristol, Bristol, UK
Email: Elek.Molnar@bristol.ac.uk
Web URL: http://www.bris.ac.uk/neuroscience/

Keywords: glutamate receptors, AMPA, kainate, NMDA, development, synaptic plasticity, LTP, LTD, receptor targeting, oligodendrocytes

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Anne N. Murphy

University of California San Diego, La Jolla, CA, USA
Email: anmurphy@cox.net

Keywords: biochemistry, bioenergetics, metabolism mitochondria, Ca2 , oxidative phosphorylation, neurodegeneration, electron transport, ion transport, excitotoxicity, membrane potential, mitochondrial ion transport, mitochondrial biogenesis, mitochondrial movement and morphology, mitochondrial free radical generation

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Eric J. MurphyEric J. Murphy

University of North Dakota, Grand Forks, ND, USA
Email: emurphy@medicine.nodak.edu

Keywords: broad lipid metabolism in the CNS, fatty acids, phospholipids, including ether lipids, and acylhydrolases, such as phospholipase A2; alterations of lipid metabolism in pathophysiological states, e.g. Alzheimer's disease, Down's syndrome, CNS diseases

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Akihiko Nunomura

Yamanashi University, Chuo, Yamanashi, Japan
Email: anunomura@yamanashi.ac.jp

Keywords: RNA, aging, Alzheimer’s disease, apoptosis, cell cycle, free radicals, hippocampus, immunocytochemistry, metabolism, metals, mitochondria, neurodegeneration, nutrition, oxidative stress, Parkinson’s disease

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Jean-Noël OctaveJean-Noël Octave

Université Catholique de Louvain, Brussels. Belgium
Email: octave@nchm.ucl.ac.be

Keywords: Alzheimer’s disease: cellular and animal models, neurodegenerative diseases, cloning and expression, adenoviruses as expression vectors both in vitro and in vivo, cell biology, cell culture, primary cultures of neurones, signal transduction

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Arturo OrtegaArturo Ortega

Cinvestav-IPN, Mexico City, Mexico
Email: arortega@cinvestav.mx

Keywords: signal transduction, transcriptional regulation, Bergmann glia, glutamate receptors

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David S. Park

University of Ottawa, Ontario, Canada
Email: dpark@uottawa.ca

Keywords: Chk1, Cdc25A, DNA damage, cell cycle, apoptosis, neurons

________________________________________



Maria PassafaroMaria Passafaro

Dulbecco Telethon Institute, Milan, Italy
Email: m.passafaro@in.cnr.it

Keywords: excitatory glutamate synapses, genetic disorders, molecular mechanisms of synapse formation

________________________________________



Peter PenzesPeter Penzes

Northwestern University, Chicago, IL, USA
Email: p-penzes@northwestern.edu

Keywords: dendritic spine, plasticity, actin, GEF, schizophrenia, autism, postsynaptic, signal transduction, synaptogenesis

________________________________________



Marina Picciotto

Yale University, New Haven, USA
Email: marina.picciotto@yale.edu
Phone: 1 203 737 2041Fax: 1 203 737 2043

Keywords: adducin, calmodulin kinase I (CaM kinase I), drug abuse, galanin, molecular basis of addiction, mouse models of psychiatric diseases, nicotinic acetylcholine receptors (NAChRs)

________________________________________



Marco A. M. PradoMarco A. M. Prado

The University of Western Ontario, London, ON, Canada
Email: maximo.prado@gmail.com

Keywords: cholinergic mechanisms, protein and membrane trafficking, pre-synaptic mechanisms, calcium signaling, toxins and neuronal function, prion diseases, Alzheimer´s disease, neurodegeneration, neurotransmitter transporters, synaptic vesicle

________________________________________



Alessandro PrinettiAlessandro Prinetti

Universita degli Studi di Milano, Milano, Italy
Email: alessandro.prinetti@unimi.it
Web URL: http://www.unimi.it/

Keywords: complex membrane lipid biochemistry and biophysic, biological role of sphingolipid, neuronal membranes and disease, segregation phenomena in neuronal membranes, lipid rafts in cell signalling

________________________________________



Elena A. RybnikovaElena A. Rybnikova

Russian Academy of Sciences, Pavlov Institute of Physiology, St.Petersburg, Russian Federation
Email: samoilov@pavlov.infran.ru, rybnikova1@rambler.ru
Tel: 7-813-7072850 Mobile 7-911-9541596 Fax: 7-812-3280501

Keywords: neuroendocrinology, stress, stress-related disorders, hormone-dependent mechanisms of adaptation, brain injury and tolerance, hypobaric hypoxia, molecular and cellular mechanisms of neuroprotection, preconditioning, postconditioning

________________________________________



Ester L. SabbanEsterL.Sabban

New York Medical College, Valhalla, NY, USA
Email: esther_sabban@nymc.edu

Keywords: biochemistry, molecular biology, gene expression for catecholamine-synthesizing enzymes and neuropeptides by stress, estrogens, tyrosine hydroxylase, transcription, promoter, cAMP, adrenal medulla, noradrenergic system

________________________________________



Carlo SalaCarlo Sala

CNR Institute of Neuroscience, Milan, Italy
Email: c.sala@in.cnr.it
Phone: 39 025031 7096 Fax: 39 02749 0574

Keywords: autism spectrum disorders, dendritic spines, intellectual disabilities, memory, mental retardation, neurodegenerative disorders, postsynaptic mechanisms, proteomics, synaptic plasticity, synaptic proteins, synaptic transmission, synaptogenesis

________________________________________



Michael F. SalvatoreMichael F. Salvatore

LSU Health Sciences Center, Shreveport, LA, USA
Phone: 1 318 675-7874
Email: msalva@lsuhsc.edu

Keywords: aging, dopamine regulation in vivo, dopamine transporter, glutamate, locomotor function, nigrostriatum, Parkinson’s disease, protein phosphorylation, stimulants, tyrosine hydroxylase

________________________________________



Ana M. SebastiãoAna M. Sebastião

University of Lisbon, Lisboa, Portugal
Email:
anaseb@fm.ul.pt
Web URL:
http://www.imm.fm.ul.pt/web/imm/neurosciencesunit

Keywords: neuromodulation of synaptic transmission, in particular at the hippocampus, cross-talk between neuromodulatoras, focusing on neurotrophins, adenosine, neuropeptides and cannabinoids, neuroprotection. adenosine receptors and adenosine transporters, G-protein coupled receptors and kinase receptors

________________________________________



Frank R. SharpFrank R. Sharp

University of California at Davis, Sacramento, CA, USA
Email: frank.sharp@ucdmc.ucdavis.edu

Keywords: stroke and cerebral ischemia, heat shock and immediate early gene expression in brain, cerebral glucose and glycogen metabolism, neurogenesis and gliogenesis following ischemia, genomics and proteomics of neurological diseases

________________________________________



Tomoaki Shirao

Gunma University Graduate School of Medicine, Gunma, Japan
Email: tshirao@med.gunma-u.ac.jp
Phone: 81 27 220 8050 Fax: 81 27 220 8053

Keywords: actin filaments, dendritic spines, growth cone, myosin, neurite outgrowth, neuronal culture, synapse formation, synaptic plasticity, time-lapse imaging

________________________________________



Weihong SongWeihong Song

The University of British Columbia, Vancouver, Canada
Email: weihong@exchange.ubc.ca

Keywords: Alzheimer's disease, secretases, amyloid, stroke, hypoxia, Parkinson’s disease, Huntington’s disease, aging, mental disorders, neuronal apoptosis, transcriptional regulation, gene expression, molecular genetics, signal transduction

________________________________________



Maria de Souza Silva

University of Duesseldorf, Duesseldorf, Germany
Email: desouza@uni-duesseldorf.de

Keywords: neuropeptides, neurokinin, intranasal, microdialysis, learning and memory, acetylcholine, dopamine

________________________________________



David G. StandaertDavid G. Standaert

University of Alabama at Birmingham, Birmingham, AL, USA
Email: dstandaert@uab.edu
Web URL: www.uab.edu/CNET

Keywords: NMDA receptors, glutamate receptors, Parkinson's disease, dystonia, synuclein

________________________________________



Jörg StehleJörg Stehle

Goethe University Frankfurt, Frankfurt, Germany
Email: stehle@em.uni-frankfurt.de

Keywords: cAMP-signalling pathway, circadian, clock gene, hippocampus, melatonin, pineal organ, rhythm, transcriptional regulation

________________________________________



Tetsuya Terasaki

Tohoku University, Sendai, Japan
Email: terasaki@mail.pharm.tohoku.ac.jp
Web URL: http://www.pharm.tohoku.ac.jp/~soutatsu/dds/index.htm

Keywords: Blood-brain barrier, transport, P-glycoprotein, abc transporter, drug delivery, pharmacokinetics, brain microdialysis, slc transporter, bcrp, mrp transporter

________________________________________



Roxanne A. VaughanRoxanne A. Vaughan

University of North Dakota School of Medicine, Grand Forks, ND, USA
Email: rvaughan@medicine.nodak.edu

Keywords: molecular mechanisms of dopamine transporters including phosphorylation, photoaffinity labeling, and structure-function analysis. Neurotransmitter transporters, cocaine binding, dopamine regulation, receptor or transporter phosphorylation, and receptor or transporter photoaffinity labeling

________________________________________



Jose L. VeneroJose L. Venero

University of Sevilla, Sevilla, Spain
Email: jlvenero@us.es

Keywords: Microglia, substantia nigra, peroxynitrites, Parkinson's disease, minocycline, dopaminergic system

________________________________________



Bryce Vissel

Garvan Institute, Sydney, Australia
Email: b.vissel@garvan.org.au

Keywords: Neurogenesis , stem cells , neurodegeneration , Parkinson's disease , Alzheimer's disease, Dopamine neurons, Excitotoxicity, neural stem cells, neural precursor cells, neural regeneration, synaptic transmssion, glutamate receptors, RNA editing

________________________________________



Helle S. WaagepetersenHelle S. Waagepetersen

University of Copenhagen, Copenhagen, Denmark
Email: hsw@farma.ku.dk
Web URL: http://www.neurometabolism.dk

Keywords: Brain energy metabolism, neurons, astrocytes, d-aspartate, ATP, transport, norepinephrine, lactate, cellular metabolism

________________________________________



Michael WellerMichael Weller

University Hospital Zurich, Zurich, Switzerland
Email: michael.weller@usz.ch
Web URL: http://www.neurologie.usz.ch

Keywords: glioma, astrocytoma, apoptosis, cell death, astrocyte, stem cell, death receptors, death ligands, neuroimmunology

________________________________________



Wolfgang WickWolfgang Wick

University Clinic Heidelberg, Heidelberg, Germany
Email: wolfgang.wick@med.uni-heidelberg.de
Phone: 49 (0) 6221-56/7337 Fax: 49 (0) 6221-56/7554

Keywords: cell migration and invasion, glioma, hypoxia, neurooncology, tumor microenvironment, tumor suppressor gene

________________________________________



Stephen R. WilliamsStephen R. Williams

University of Manchester, Manchester, UK
Email: steve.williams@manchester.ac.uk

Keywords: Nuclear Magnetic Resonance, MRI, MRS, stroke, ischaemia, energy metabolism, neurotransmitter metabolism, cerebral blood flow

________________________________________



Marina E. WolfMarina E. Wolf

Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA
Email: marina.wolf@rosalindfranklin.edu
Web URL: www.rosalindfranklin.edu

Keywords: glutamate, dopamine, NMDA receptors, AMPA receptors, microdialysis, in situ hybridization, immunocytochemistry, Addiction, plasticity, receptor trafficking, glutamate receptors, dopamine receptors, cocaine, amphetamine

________________________________________



Yung H. WongYung H. Wong

The Hong Kong University of Science & Technology, Hong Kong, China
Email: boyung@ust.hk
Web URL: http://life-sci.ust.hk/faculty/Prof.Y.H.Wong/index.html

Keywords: Opioid peptides and receptors, signal transduction, neuropeptides, G proteins, melatonin, neuropharmacology, opioid tolerance and dependence

________________________________________



Ian C. WoodIan C. Wood

University of Leeds, Leeds, UK
Email: i.c.wood@leeds.ac.uk
Web URL: http://www.fbs.leeds.ac.uk/..?tag=Wood_I

Keywords: Chromatin, transcription, Gene regulation, transcription factors, epigenetics, epilepsy, transgenic mice, DNA, mRNA, expression, differentiation, stem cells

________________________________________



Bryan YamamotoBryan Yamamoto

University of Toledo Health Sciences Campus, Toledo, OH, USA
Email: Bryan.Yamamoto@utoledo.edu

Keywords: excitotoxicity, drug abuse, amphetamines, oxidative stress, neurodegeneration

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