Journal of Neurochemistry

Cover image for Vol. 134 Issue 1

Edited By: Jörg Schulz

Impact Factor: 4.281

ISI Journal Citation Reports © Ranking: 2014: 55/252 (Neurosciences); 72/289 (Biochemistry & Molecular Biology)

Online ISSN: 1471-4159

Virtual Issues

Click on the links below to jump to each issue

Neuroinflammation in Nervous System Disorders: Diversity in Insults and Outcomes

Molecular imaging and its applications – Visualization beyond imagination, October 2013

The increasing involvement of Latin American Countries in the Development of Modern Neurochemistry, June 2012

Nicotinic Acetylcholine Receptors, October 2009

Cerebral ischemia - pathology and potential countermeasures April 2008

Alzheimer's disease April 2008


Neuroinflammation in Nervous System Disorders: Diversity in Insults and Outcomes


Under non-diseased conditions, central nervous system (CNS) homeostasis is maintained by an intricate crosstalk between glia and neurons. However, in response to CNS infection or injury, glial cells become activated and contribute to ensuing inflammatory processes, in either a beneficial or detrimental manner, depending on the nature, intensity, and duration of the insult. This Virtual Issue brings together selected prior publications in the Journal of Neurochemistry that highlight the diverse insults and outcomes of neuroinflammatory responses in the CNS, serving to provide insights into the important role that neuroinflammation plays across a diverse set of CNS diseases/disorders.

Molecular Imaging

This Virtual Issue is dedicated to imaging methods covering magnetic resonance imaging (MRI), mass spectrometry, fluorescence imaging, X-ray, positron emission tomography (PET), and stimulated emission depletion (STED). Much of the initial enthusiasm for MRI stemmed from its ability to identify pathology and pathogenesis in multiple sclerosis and stroke; early applications of PET were concerned with imaging fluoro-deoxyglucose uptake in the brain; functional imaging with MRI, fluorodeoxyglucose-PET and water-PET have transformed cognitive neurosciences. The selected articles are representative of the broad methods and their applications, albeit the list cannot be exhaustive.


The increasing involvement of Latin American Countries in the Development of Modern Neurochemistry

Neuroscience in South America

Science in Latin America has been developed strongly in the last 20 years and a good tradition in Neurochemistry has been present in our countries since the classic works by De Robertis in Argentina, Fernando Garcia de Mello in Brazil, Ricardo Tapia in Mexico and may other enthusiastic scientists that decided to study the brain from a biochemical perspective. The Journal of Neurochemistry as the leading periodic publication in this area honours this time the most relevant papers published in the last decade from our region. As with any selection, surely our list is incomplete and might be missing high quality work, we definitely apologize for our omission. As the reader goes through the selected papers, it will become clear that the work of our fellow Latin American scientists impacts in seven thematic areas of Modern Neurochemistry: Genetics and Gene Regulation, Brain Development and Cell differentiation, Signal Transduction and Synaptic Transmission, Bioenergetics and metabolism, Neuroinfammation and neuroimmunology, Neuronal Plasticity and behaviour and the Molecular Basis of Disease... Read full introduction

Vilma Martins
Arturo Ortega

Genetics and Gene Regulation

Brain Development & Cell Differentiation

Signal Transduction & Synaptic Transmission

Bioenergetics & Metabolism

Neuroinflammation & Neuroimmunology

Neuronal Plasticity & Behavior

Molecular Basis of Disease


Nicotinic Acetylcholine Receptors, October 2009

Nicotinic acetylcholine receptors (nAChRs) have come of age! The large family of vertebrate and invertebrate subunits gives rise to multiple subtypes of nAChR expressed in neuronal, muscle and many non-excitable tissues. As well as mediating the physiological actions of acetylcholine, nAChRs are implicated in the pathogenesis or treatment of neurodegenerative and neuropsychiatric diseases, they mediate the dependence-producing effects of nicotine that underlie tobacco smoking, and they are targets for neonicotinoid pesticides. The structural heterogeneity and functional diversity of nAChRs has stimulated a raft of research to interrogate these receptors at various levels, from structure-function relationships, to cell signalling and in vivo consequences. This virtual issue of recent nAChR research papers published in the Journal of Neurochemistry reflects the quality and variety of studies emanating form some of the top international laboratories, and includes papers from Australia, China, Europe, South America and the USA.


Cerebral Ischemia - pathology and potential countermeasures, April 2008
Edited by Sean Murphy


Alzheimer's Disease, April 2008