Letters in Applied Microbiology

Cover image for Vol. 65 Issue 4

Edited By: J.-Y. Maillard

Impact Factor: 1.575

ISI Journal Citation Reports © Ranking: 2016: 93/124 (Microbiology); 108/158 (Biotechnology & Applied Microbiology)

Online ISSN: 1472-765X

Associated Title(s): Journal of Applied Microbiology

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Recently Published Articles

  1. Subtractive phage display selection for screening and identification of peptide sequences with potential use in serodiagnosis of paracoccidioidomycosis caused by Paracoccidioides brasiliensis

    L. da Silva Portes, E.S. Kioshima, Z.P. de Camargo, W.L. Batista and P. Xander

    Version of Record online: 21 SEP 2017 | DOI: 10.1111/lam.12788

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    Significance and Impact of the Study: Currently, there is no standardized method for the preparation of paracoccidioidomycosis (PCM) antigens, which has resulted in differences in the antigens used for serological diagnosis. Here, we report a procedure that uses subtractive phage display selection to select and identify new epitopes for the serodiagnosis of PCM caused by Paracoccidioides brasiliensis. A synthetic peptide obtained using this methodology was successfully recognized by sera from PCM patients, thus demonstrating its potential use for improving the serodiagnosis of this mycosis. The development of synthetic peptides for the serodiagnosis of PCM could be a promising alternative for the better standardization of diagnoses among laboratories.

  2. Effect of storage temperatures and stresses on the survival of Salmonella spp. in halva

    T.M. Osaili, A.A. Al-Nabulsi, D.S. Nazzal and R.R. Shaker

    Version of Record online: 20 SEP 2017 | DOI: 10.1111/lam.12791

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    Significance and Impact of the Study: Contamination of halva (tahini halva) with Salmonella from raw materials or during production was documented. Halva and tahini have been involved in salmonellosis outbreaks in different countries. The study demonstrated enhanced survivability of stressed and unstressed Salmonella spp. in halva over a 12-month storage period at 10 and 25°C with lower log reductions than expected. Exposing Salmonella spp. to desiccation or heat stress prior product contamination may play a role in microbial survival in halva during storage. These findings serve as a model to halva producers to implement control measures to prevent Salmonella spp. contamination in halva.

  3. Postantibiotic effect and postantibiotic sub-MIC effect of LTX-109 and mupirocin on Staphylococcus aureus blood isolates

    L.D. Saravolatz, J. Pawlak, H. Martin, S. Saravolatz, L. Johnson, H. Wold, M. Husbyn and W.M. Olsen

    Version of Record online: 19 SEP 2017 | DOI: 10.1111/lam.12792

    Significance and Impact of the Study: Resistant bacterial infections continue to be a challenge for clinicians. Identification of antibiotics with pharmacodynamic advantages may be beneficial in the treatment of these infections. An antibiotic with a longer postantibiotic effect may be able to be administered less frequently resulting in improved adherence. In this study, a new synthetic antimicrobial peptide, LTX-109, demonstrated a more prolonged time for LTX-109 than mupirocin against methicillin-resistant Staphylococcus aureus.

  4. Isolation and characterization of a novel deoxynivalenol-transforming strain Paradevosia shaoguanensis DDB001 from wheat field soil

    Y. Wang, H.H. Zhang, C. Zhao, Y.T. Han, Y.C. Liu and X.L. Zhang

    Version of Record online: 19 SEP 2017 | DOI: 10.1111/lam.12790

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    Significance and Impact of the Study: Deoxynivalenol (DON) is one of the most frequently found mycotoxins in all major cereal grains worldwide. A DON-transforming bacterium, Paradevosia shaoguanensis DDB001, was isolated from wheat field soil. This study is the first report on isolation of a member of the genus Paradevosia as a potent DON-transformation micro-organism. The isolated bacterium has the potential to be utilized for detoxification of DON-contaminated feed.

  5. Identification of proteome, antigen protein and antigen membrane protein from Spiroplasma eriocheiris

    Y. Liu, Y. Xu, S. Li, X. Xu, Q. Gao, M. Yuan, W. Gu, W. Wang and Q. Meng

    Version of Record online: 19 SEP 2017 | DOI: 10.1111/lam.12784

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    Significance and Impact of the Study:Spiroplasma eriocheiris is a novel pathogen causing the tremor disease in Chinese mitten crab Eriocheir sinensis. This is the first time LC-MS/MS was used to identify the proteome, antigen protein and antigen membrane protein of S. eriocheiris. The results can certainly provide valuable information towards the identification of virulent proteins or diagnosis of pathogenic mechanisms.

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