Letters in Applied Microbiology

Cover image for Vol. 62 Issue 2

Early View (Online Version of Record published before inclusion in an issue)

Edited By: J.-Y. Maillard

Impact Factor: 1.659

ISI Journal Citation Reports © Ranking: 2014: 90/119 (Microbiology); 101/163 (Biotechnology & Applied Microbiology)

Online ISSN: 1472-765X

Associated Title(s): Journal of Applied Microbiology


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  1. Original Articles

    1. Molecular detection and characterization of noroviruses in river water in Thailand

      K. Inoue, K. Motomura, M. Boonchan, N. Takeda, K. Ruchusatsawa, R. Guntapong, R. Tacharoenmuang, S. Sangkitporn and S. Chantaroj

      Article first published online: 4 FEB 2016 | DOI: 10.1111/lam.12529

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      Significance and Impact of the Study: Our study is the first paper that multiple genogroups and genotypes of norovirus exist, and are circulating in the river water near Bangkok, Thailand. Phylogenetic analysis indicated the presence of four GII.4 variant groups pro-circulated after the Den Haag_2006b, New Orleans_2009 and Sydney_2012 that caused outbreaks in the world. Continued research will be essential for understanding the natural history of NoV and the control of future outbreaks.

    2. Maximum-biomass concentration prediction for Bifidobacteria in the pH-controlled fed-batch culture

      S.M. Cui, J.X. Zhao, X.M. Liu, Y.Q. Chen, H. Zhang and W. Chen

      Article first published online: 4 FEB 2016 | DOI: 10.1111/lam.12540

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      Significance and Impact of the Study: This study provides further insights into the inhibition of Bifidobacteria by dissociated acid anions (the dissociated form) at pH 7·0. The high correlation between different strains suggested that the equation established in this paper is appropriate for different strains of Bifidobacteria. The prediction equation could be used to guide practical production in the preparation of materials, the control of the end of fermentation and production plans for further products such as freeze-dried powder of Bifidobacteria or food fermentation.

    3. Activity of Polish unifloral honeys against pathogenic bacteria and its correlation with colour, phenolic content, antioxidant capacity and other parameters

      P.M. Kuś, P. Szweda, I. Jerković and C.I.G. Tuberoso

      Article first published online: 2 FEB 2016 | DOI: 10.1111/lam.12541

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      Significance and Impact of the Study: Honey is a promising agent in the treatment of non-healing infected wounds. Thirty-seven unifloral samples of 14 honey varieties from Poland were analysed for their antimicrobial activity and compared with manuka honey. Several honey types exert even higher antimicrobial potential and could be introduced to wound therapy. Additionally, positive correlations of the antimicrobial activity were found, especially with yellow colour and could be important in the search and screening of the honey active against Escherichia coli.

    4. The role of reactive oxygen species in the antibacterial photodynamic treatment: photoinactivation vs proliferation

      N. Topaloglu, M. Guney, N. Aysan, M. Gulsoy and S. Yuksel

      Article first published online: 2 FEB 2016 | DOI: 10.1111/lam.12538

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      Significance and Impact of the Study: The main purpose in antibacterial photodynamic therapy (PDT) is to kill the micro-organisms that cannot be destroyed by conventional methods. Low-level light and/or low concentration of reactive oxygen species may trigger some biochemical pathways that lead to cell proliferation. Thus, there is a risk of bacterial cell proliferation during PDT. In this study we report that PDT with ICG application can induce biostimulation when laser dose and photosensitizer concentration are not optimized properly. Therefore, optimum dosimetry in PDT possesses great importance in the treatment of wounds infected by antibiotic-resistant bacteria.

    5. Sequence-based methods for detecting and evaluating the human gut mycobiome

      M.J. Suhr, N. Banjara and H.E. Hallen-Adams

      Article first published online: 2 FEB 2016 | DOI: 10.1111/lam.12539

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      Significance and Impact of the Study: Fungi play a role in human gut ecology and health. The field lags immensely behind bacterial gut microbiota research, and studies continue to identify new fungi in faecal samples from healthy humans. However, many of these ‘new’ species are incapable of growth in the human GI tract, let alone making a meaningful contribution to the gut microbial community. Fungi actually inhabiting and impacting the gut likely constitute a small set of species, and an optimized, targeted, probe-based assay may prove to be the most sensible way of quantifying their abundances.

    6. Accurate identification of members of the Burkholderia cepacia complex in cystic fibrosis sputum

      M. Martinucci, E. Roscetto, V.D. Iula, A. Votsi, M.R. Catania and E. De Gregorio

      Article first published online: 2 FEB 2016 | DOI: 10.1111/lam.12537

      Significance and Impact of the Study: Burkholderia cepacia complex (BCC) has a complex taxonomic organization and its identification is a challenge for microbiology laboratories. Nonidentification or misidentification of BCC isolates represent a problem in epidemiology and treatment of cystic fibrosis patients. The high specificity and sensitivity of the multiplex Real-time PCR assay developed in this study indicates its potential to be a rapid and reliable method for the detection of Burkholderia at the level of species from sputum samples of cystic fibrosis patients.

    7. Bifidobacteria possess inhibitory activity against dipeptidyl peptidase-IV

      Z. Zeng, J.Y. Luo, F.L. Zuo, R. Yu, Y. Zhang, H.Q. Ma and S.W. Chen

      Article first published online: 28 JAN 2016 | DOI: 10.1111/lam.12510

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      Significance and Impact of the Study: Our results show that Bifidobacteria isolated from breast-fed infants’ faecal samples possess DPP-IV inhibitory activity. Strains of Bifidobacterium bifidum IF3-211 and Bifidobacterium adolescentis IF1-11, which showed excellent DPP-IV inhibitory properties as well as good in vitro probiotic properties, are expected to be beneficial for application as anti-diabetic probiotics.


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