Fundamental & Clinical Pharmacology

Cover image for Vol. 29 Issue 6

Edited By: Pascal Bousquet and Atul Pathak

Impact Factor: 2.121

ISI Journal Citation Reports © Ranking: 2014: 140/254 (Pharmacology & Pharmacy)

Online ISSN: 1472-8206

Author Guidelines

Online-only publication from 2016

Fundamental & Clinical Pharmacology will be published in online-only format effective with the 2016 volume. This is a proactive move towards reducing the environmental impact caused by the production and distribution of printed journal copies and will allow the journal to invest in further digital development. Published articles will continue to be disseminated quickly through the journal’s broad network of indexing services, including ISI, MEDLINE and Scopus. Articles will also continue to be discoverable through popular search engines such as Google. All color images will now be reproduced digitally and published free of charge.

‘ScholarOne Manuscripts’ online submission system

Manuscripts should be submitted online at:

If you are already a registered user, type in your User ID (typically your e-mail address) in the ‘Log in’ section. If you forgot your password, use ‘Password Help’.

If you are a new user, first choose ‘Create Account’ (top right corner) or register under ‘New User?’.

When submitting your manuscript in your Author Centre, you must go through 7 steps.
Please select the ‘Manuscript Type’, ‘Subject Area’ - the manuscript will be allocated to the corresponding Editor in chief - and ‘Area of Speciality’ that most closely fit with the topic of your paper. In the ‘Areas of Speciality’ list, ‘Not Applicable’ may be selected if your paper does not fall within one of the listed domains.

If your manuscript is in the WORD format (tables and figures included), you can upload it as one file and designate it as ‘Main Document’.

You may interrupt the submission process of a manuscript and resume later under “Unsubmitted Manuscripts” in your Author Centre.

You will find instructions that may be helpful on the top of every screen in ScholarOne Manuscripts. The ‘Get Help Now’ tab also provides you with valuable information.

All correspondence should be e-mailed to the Editorial Office :

Postal Address :
Laboratoire de Neurobiologie et Pharmacologie Cardiovasculaire
Faculté de Médecine
11 rue Humann
67085 Strasbourg cedex

Fax : +33 3 68 85 33 88

All manuscripts should be accompanied by a clear statement that the work has not been published elsewhere and is not under review with another journal. When there is more than one author, a clear statement should be made in the submission letter that ALL co-authors have agreed to the submission of the final manuscript.
Authors should keep copies of all material submitted. No materials will be returned.
Authors will provide a list of three candidate referees (including names, emails, addresses and phone) who are not directly concerned with the research being submitted. The Editors reserve the right to choose different referees from the ones suggested.

WORD 2007
Fundamental and Clinical Pharmacology now accepts submission in Word 2007 format. As such manuscripts can be submitted in both .doc and .docx file types.

Types of Manuscripts Accepted
The Journal publishes new material only. Authors should not submit work that has been published elsewhere, except in abstract form, and where a previous abstract has been published clear reference must be made to it in the Introduction.
The major part of each issue will be devoted to Original articles. These must describe significant and original observations and provide sufficient detail so that the observations can be critically evaluated and, if necessary, repeated. Short communications and Review articles will also be included in the Journal (see below for details).

According to the editorial policy of the journal, studies are taken into consideration when compounds or molecules are highly purified and when the active product/compound is chemically identified. All details about the compound should be included in the Material and Methods section : how it was obtained or its origin, as well as its chemical structure and purity degree.

Organization of the Manuscript

This must include in the following order: title - a full title (30 to 40 words) and a running title (6 to 10 words); authors' names -first names and surnames of each author, name and address (including full postal address, e-mail address, telephone and fax numbers) of the person who will deal with correspondence, including proofs; affiliation - address(es) from which the work originated linked to authors' names by superscript (a, b, c...); abstracts and keywords -an abstract (max. 250 words - no section titles) outlining the study in its entirety and a list of three to six keywords should be included; abbreviations -a list of abbreviations used may be included. Abbreviations should be kept to an absolute minimum. The word must always be written out in full when first used and the proposed abbreviation given in parentheses.

Original articles should not exceed 5000 words and should contain the following section: Introduction, which outlines the historical or logical origins of the study without repeating the abstract or summarizing the results; Materials and methods; Results in which the observations are presented with minimal reference to earlier literature or to possible interpretations; Discussion may usefully start with a brief summary of the major findings, but repetition of parts of the abstract or of the results section should be avoided; and Conclusion. The sections Acknowledgements, References, Tables, Figures, Figure Legends and Footnotes should follow the main text on separate sheets and in that order. There should be an indication in the main text to show the most appropriate placement of each table and figure.

References to articles, chapters, monographs or other publications should be in the Vancouver style, i.e. they should be numbered sequentially (by Arabic numerals in [brackets], e.g. [1]) in the order in which they are first mentioned in the text. In the list of references, references are listed numerically. References cited only in legends should be numbered in accordance with a sequence established by the first identification in the text of the particular table or illustration. The references themselves should be abbreviated according to the style used in Index Medicus or the World List of Scientific Periodicals, 4th edition. Unpublished observations and personal communications should not be listed but may be inserted in the text. Papers which have been accepted for publication should be included in the list of references as 'in press'. Authors are responsible for verifying the wording of all references and that references of unpublished work are approved by the original author.

In the list of references, journal articles should be listed as follows:

[1]   Puybasset L., Giudicellli J.F., Berdeaux A. Coronary effects of exogenous and endogenous bradykinin in conscious dogs. Fundam. Clin. Pharmacol. (1997) 11 322-330

Books should be listed as:
[2]   Brown H. & Kozlowski R. Physiology and Pharmacology of the Heart. Blackwell Science Ltd, Oxford, UK. 1997.
[3]  Marshall J., Pharmacologic Treatment of Gastrointestinal Malignancies, in: Lewis J.H. & DuBois A. (Eds.), Current Clinical Topics in Gastrointestinal Pharmacology, Blackwell Science Inc., Boston, USA. 1997, pp 224-241

There is no limit set on the number of illustrations, but authors should use them sparingly, making sure that each figure is relevant to the text and that the figures are presented in the order in which they are mentioned in the text. Line drawings and photographs should be consecutively numbered with Arabic numerals (1, 2, etc.). Tables should be consecutively numbered with Roman numerals (I, II, etc.). Each figure and table submitted should be clearly labelled with the name of the author(s), the title of the paper and the figure or table number. Wherever possible illustrations should be submitted in their desired final size, to fit the width of a single column of text, i.e. 88 mm wide, or where it is necessary they should be 184 mm in maximum width. The final size of the printed figure cannot exceed 230 × 184 mm including legends, and where a reduction is required this should be indicated on the figures. Figure and table legends should explain each figure and table as fully as possible, referring the reader to the text only on rare occasions in order to avoid repeating in the legends material that must be included in the text.

It is the policy of Fundamental & Clinical Pharmacology for authors to pay the full cost for the reproduction of their colour artwork. Therefore, please note that if there is colour artwork in your manuscript when it is accepted for publication, Wiley requires you to complete and return a Colour Work Agreement Form before your paper can be published. This form can be downloaded as a PDF* from the internet.

If you are unable to access the internet, or are unable to download the form, contact the Production Editor who will be able to email or fax a form to you: and she will be able to email or fax a form to you.

Please post or courier all pages of your completed form to:

Customer Services (OPI)
John Wiley & Sons Ltd
European Distribution Centre
New Era Estate
Oldlands Way
Bognor Regis
West Sussex
PO22 9NQ

Please note that electronic or faxed copies cannot be accepted. For queries, please contact the Production Editor.

Please note that funds will be collected after the article is published in print.

Any article received by Wiley with colour work will not be published until the form has been returned.

* To read PDF files, you must have Acrobat Reader installed on your computer. If you do not have this program, this is available as a free download from the following web address:

The journal allows authors to publish figures in colour free of charge in the online edition. Authors must provide their figures in digital format (EPS or TIF files at high resolution) and indicate to the Editorial Office that they wish to publish in Black & White in the print edition and in colour in the online edition. In this case, (a) a single version of the figure should be supplied in colour which will be converted by the publishers to black and white for the print journal and (b) the figure legend should not refer to colour as it will be used for both versions.

Electronic artwork
The journal welcomes submission of artwork electronically. Please refer to our electronic media pages, available on the journal’s homepage at, for more information.

Short communications
Short communications that describe highly original findings and that justify rapid publication will also be considered for publication in the Journal. Short communications should be limited to 1000 words including references, or the equivalent space if tables and figures, which should be kept to a minimum, are included. Each short communication should be preceded by a succinct summary. Manuscripts need not be divided into sections as for full length papers but can be so divided at the author's discretion. Editorial and publishing procedures will be expedited to assure rapid publication. In general, papers will be either accepted or rejected. Papers that require significant modification in response to referees' comments will be rejected.

Review Articles
Review articles are commentaries on topics of particular interest and they will be peer-reviewed.

Experimental Subjects
When human subjects are used, manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding and written consent of each subject. Authors should be aware of the Code of Ethics of the World Medical Association (Declaration of Helsinki), which has been printed in the British Medical Journal (18 July 1964).

When experimental animals are used the methods section must clearly indicate that adequate measures were taken to minimize pain or discomfort. Experiments should be carried out in accordance with the European Communities Council Directive of 24 November 1986 (86/609/EEC) or with the Guidelines laid down by the NIH in the US regarding the care and use of animals for experimental procedures. All studies using human or animal subjects should include an explicit statement in the Methods section identifying the review and approval committee for each study.

Editors reserve the right to reject papers if there is doubt whether appropriate procedures have been used.

Proofs and Offprints
Proofs will be sent via e-mail as an Acrobat PDF (portable document format) file. The e-mail server must be able to accept attachments up to 4 MB in size. Acrobat Reader will be required in order to read this file. This software can be downloaded (free of charge) from the following Web site:

This will enable the file to be opened, read on screen, and printed out in order for any corrections to be added. Further instructions will be sent with the proof. Proofs will be posted if no e-mail address is available; in your absence, please arrange for a colleague to access your e-mail to retrieve the proofs.
The corresponding author will receive a PDF 'reprint' of his or her article. Printed offprints can be supplied if ordered on the offprint form which accompanies the proofs.

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and visit

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy please visit:


OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive.

For the full list of terms and conditions, see

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at:

Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

Accepted Articles

Further to acceptance in Fundamental & Clinical Pharmacology, manuscripts are immediately made publicly available online. 'Accepted Articles' have been peer-reviewed and accepted for formal publication, but have not been subject to copyediting, composition or proof correction. The service provides for the earliest possible dissemination of research data following article acceptance. Accepted Articles appear in PDF format only and are given a Digital Object Identifier (DOI), which allows them to be cited and tracked. The DOI remains unique to a given article in perpetuity and can continue to be used to cite and access the article further to print publication. More information about DOIs can be found online at . Accepted Articles will be indexed in PubMed.

Fundamental & Clinical Pharmacology nor Wiley can be held responsible for errors or consequences arising from the use of information contained in Accepted Articles; nor do the views and opinions expressed necessarily reflect those of Fundamental & Clinical Pharmacology or Wiley.

Early View
e are happy to announce that Fundamental & Clinical Pharmacology is now part of the Wiley Online Library Early View service. Articles will now be published on a regular basis online in advance of their appearance in a print issue. These articles are fully peer reviewed, edited and complete - they only lack page numbers and volume/issue details - and are considered fully published from the date they first appear online. This date is shown with the article in the online table of contents. Because Early View articles are considered fully complete, please bear in mind that changes cannot be made to an article after the online publication date even if it is still yet to appear in print.

The articles are available as full text HTML or PDF and can be cited as references by using their Digital Object Identifier (DOI) numbers. For more information on DOIs, please see
To view all the articles currently available, please visit Fundamental & Clinical Pharmacology at the Wiley online content platform and simply click on the 'Early View' area at the top of the list of issues available to view. On print publication, the article will be removed from the Early View area and will appear instead in the relevant online issue, complete with page numbers and volume/issue details. No other changes will be made. The implementation of Early View for Fundamental & Clinical Pharmacology represents our commitment to get manuscripts available to view to the academic community as quickly as possible, reducing time to publication considerably without sacrificing quality or completeness.

Author Services
Author Services enables authors to track their article - once it has been accepted - through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production. The author will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.