Aging Cell

Cover image for Vol. 13 Issue 2

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Peter Adams, Adam Antebi, Ana Maria Cuervo, Brian Kennedy and John Sedivy

Impact Factor: 5.705

ISI Journal Citation Reports © Ranking: 2012: 3/47 (Geriatrics & Gerontology); 40/185 (Cell Biology)

Online ISSN: 1474-9726

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  1. 1 - 31
  1. Original Articles

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      Essential role for the TRF2 telomere protein in adult skin homeostasis

      Paula Martínez, Iole Ferrara-Romeo, Juana M. Flores and Maria A. Blasco

      Article first published online: 14 APR 2014 | DOI: 10.1111/acel.12221

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      A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans

      Manish Chamoli, Anupama Singh, Yasir Malik and Arnab Mukhopadhyay

      Article first published online: 21 MAR 2014 | DOI: 10.1111/acel.12218

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      Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity

      Jia Hu, Min Wei, Hamed Mirzaei, Federica Madia, Mario Mirisola, Camille Amparo, Shawna Chagoury, Brian Kennedy and Valter Longo

      Article first published online: 20 MAR 2014 | DOI: 10.1111/acel.12202

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      Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

      Rona Baron, Alicia A. Babcock, Anna Nemirovsky, Bente Finsen and Alon Monsonego

      Article first published online: 18 MAR 2014 | DOI: 10.1111/acel.12210

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      Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster

      Jessica M. Hoffman, Quinlyn A. Soltow, Shuzhao Li, Alfire Sidik, Dean P. Jones and Daniel E. L. Promislow

      Article first published online: 18 MAR 2014 | DOI: 10.1111/acel.12215

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  3. Short Takes

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      In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice

      Angela Logan, Irina G. Shabalina, Tracy A. Prime, Sebastian Rogatti, Anastasia V. Kalinovich, Richard C. Hartley, Ralph C. Budd, Barbara Cannon and Michael P. Murphy

      Article first published online: 13 MAR 2014 | DOI: 10.1111/acel.12212

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      Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

      Sofiya Milman, Gil Atzmon, Derek M. Huffman, Junxiang Wan, Jill P. Crandall, Pinchas Cohen and Nir Barzilai

      Article first published online: 12 MAR 2014 | DOI: 10.1111/acel.12213

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      Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis

      Jelena Vjetrovic, Pattabhiraman Shankaranarayanan, Marco A. Mendoza-Parra and Hinrich Gronemeyer

      Article first published online: 4 MAR 2014 | DOI: 10.1111/acel.12197

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      Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behavior, without changing mice longevity

      Alexia Gómez, Ines Sánchez-Roman, Jose Gomez, Julia Cruces, Ianire Mate, Mónica Lopez-Torres, Alba Naudi, Manuel Portero-Otin, Reinald Pamplona, Monica De la Fuente and Gustavo Barja

      Article first published online: 26 FEB 2014 | DOI: 10.1111/acel.12205

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      Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine

      Paola Gamba, Michela Guglielmotto, Gabriella Testa, Debora Monteleone, Chiara Zerbinati, Simona Gargiulo, Fiorella Biasi, Luigi Iuliano, Giorgio Giaccone, Alessandro Mauro, Giuseppe Poli, Elena Tamagno and Gabriella Leonarduzzi

      Article first published online: 25 FEB 2014 | DOI: 10.1111/acel.12206

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      Aging is associated with increased regulatory T-cell function

      Sanjay K. Garg, Colin Delaney, Tomomi Toubai, Amiya Ghosh, Pavan Reddy, Ruma Banerjee and Raymond Yung

      Article first published online: 25 FEB 2014 | DOI: 10.1111/acel.12191

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      Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

      Dao-Fu Dai, Pabalu P. Karunadharma, Ying A. Chiao, Nathan Basisty, David Crispin, Edward J. Hsieh, Tony Chen, Haiwei Gu, Danijel Djukovic, Daniel Raftery, Richard P. Beyer, Michael J. MacCoss and Peter S. Rabinovitch

      Article first published online: 25 FEB 2014 | DOI: 10.1111/acel.12203

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      Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation

      Airi Jo-Watanabe, Takamoto Ohse, Hiroaki Nishimatsu, Masao Takahashi, Yoichiro Ikeda, Takehiko Wada, Jun-ichi Shirakawa, Ryoji Nagai, Toshio Miyata, Tetsuo Nagano, Yasunobu Hirata, Reiko Inagi and Masaomi Nangaku

      Article first published online: 24 FEB 2014 | DOI: 10.1111/acel.12204

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      Genetic analysis of dTSPO, an outer mitochondrial membrane protein, reveals its functions in apoptosis, longevity, and Aβ42-induced neurodegeneration

      Ran Lin, Alessia Angelin, Federico Da Settimo, Claudia Martini, Sabrina Taliani, Shigong Zhu and Douglas C. Wallace

      Article first published online: 21 FEB 2014 | DOI: 10.1111/acel.12200

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      The contribution of visceral fat to improved insulin signaling in Ames dwarf mice

      Vinal Menon, Xu Zhi, Tanvir Hossain, Andrzej Bartke, Adam Spong, Adam Gesing and Michal M. Masternak

      Article first published online: 12 FEB 2014 | DOI: 10.1111/acel.12201

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      Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

      Richard A. Miller, David E. Harrison, Clinton M. Astle, Elizabeth Fernandez, Kevin Flurkey, Melissa Han, Martin A. Javors, Xinna Li, Nancy L. Nadon, James F. Nelson, Scott Pletcher, Adam B. Salmon, Zelton Dave Sharp, Sabrina Van Roekel, Lynn Winkleman and Randy Strong

      Article first published online: 9 FEB 2014 | DOI: 10.1111/acel.12194

  7. Short Takes

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      Smurf2 regulates hematopoietic stem cell self-renewal and aging

      Charusheila Ramkumar, Yahui Kong, Sally E. Trabucco, Rachel M. Gerstein and Hong Zhang

      Article first published online: 4 FEB 2014 | DOI: 10.1111/acel.12195

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      Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness

      Bradley S. Fleenor, Jason S. Eng, Amy L. Sindler, Bryant T. Pham, Jackson D. Kloor and Douglas R. Seals

      Article first published online: 21 JAN 2014 | DOI: 10.1111/acel.12196

  10. Original Articles

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      A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging

      Mayuko Nishimura, Caroline Kumsta, Gaurav Kaushik, Soda B. Diop, Yun Ding, Jumana Bisharat-Kernizan, Hannah Catan, Anthony Cammarato, Robert S. Ross, Adam J. Engler, Rolf Bodmer, Malene Hansen and Karen Ocorr

      Article first published online: 9 JAN 2014 | DOI: 10.1111/acel.12193

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      Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1

      Caroline Kumsta, Tsui-Ting Ching, Mayuko Nishimura, Andrew E. Davis, Sara Gelino, Hannah H. Catan, Xiaokun Yu, Chu-Chiao Chu, Binnan Ong, Siler H. Panowski, Nathan Baird, Rolf Bodmer, Ao-Lin Hsu and Malene Hansen

      Article first published online: 9 JAN 2014 | DOI: 10.1111/acel.12189

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      Reductions in serum IGF-1 during aging impair health span

      Zhenwei Gong, Oran Kennedy, Hui Sun, YingJie Wu, Garry A Williams, Laura Klein, Luis Cardoso, Ronald W. Matheny Jr, Gene B. Hubbard, Yuji Ikeno, Roger P. Farrar, Mitchell B Schaffler, Martin L Adamo, Radhika H Muzumdar and Shoshana Yakar

      Article first published online: 30 DEC 2013 | DOI: 10.1111/acel.12188

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      The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

      Nicola Raule, Federica Sevini, Shengting Li, Annalaura Barbieri, Federica Tallaro, Laura Lomartire, Dario Vianello, Alberto Montesanto, Jukka S. Moilanen, Vladyslav Bezrukov, Hélène Blanché, Antti Hervonen, Kaare Christensen, Luca Deiana, Efstathios S. Gonos, Tom B. L. Kirkwood, Peter Kristensen, Alberta Leon, Pier Giuseppe Pelicci, Michel Poulain, Irene M. Rea, Josè Remacle, Jean Marie Robine, Stefan Schreiber, Ewa Sikora, Peternella Eline Slagboom, Liana Spazzafumo, Maria Antonietta Stazi, Olivier Toussaint, James W. Vaupel, Giuseppina Rose, Kari Majamaa, Markus Perola, Thomas E. Johnson, Lars Bolund, Huanming Yang, Giuseppe Passarino and Claudio Franceschi

      Article first published online: 17 DEC 2013 | DOI: 10.1111/acel.12186

  11. Corrigendum

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      Corrigendum

      Article first published online: 13 MAR 2008 | DOI: 10.1111/j.1474-9726.2007.00381.x

      This article corrects:

      An aging Interventions Testing Program: study design and interim report

      Vol. 6, Issue 4, 565–575, Article first published online: 21 MAY 2007

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