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Aging Cell

Cover image for Vol. 16 Issue 3

Edited By: Peter Adams, Adam Antebi, Ana Maria Cuervo, Brian Kennedy and John Sedivy

Impact Factor: 5.76

ISI Journal Citation Reports © Ranking: 2015: 3/49 (Geriatrics & Gerontology); 36/187 (Cell Biology)

Online ISSN: 1474-9726

Best Paper Award


A prize of £1,000 is awarded to the first author of the winning paper in Aging Cell as judged by the Editorial Board.

2016 Winner:
Nathan Basisty, Dao-Fu Dai, Arni Gagnidze, Lemuel Gitari, Jeanne Fredrickson, Yvonne Maina, Richard P. Beyer, Mary J. Emond, Edward J. Hsieh, Michael J. MacCoss, George M. Martin and Peter S. Rabinovitch
Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: ‘reverse’ antagonistic pleiotropy?

2016 Runners Up:
Mishur, R. J., Khan, M., Munkácsy, E., Sharma, L., Bokov, A., Beam, H., Radetskaya, O., Borror, M., Lane, R., Bai, Y. and Rea, S. L.
Mitochondrial metabolites extend lifespan

Zhu, Y., Tchkonia, T., Fuhrmann-Stroissnigg, H., Dai, H. M., Ling, Y. Y., Stout, M. B., Pirtskhalava, T., Giorgadze, N., Johnson, K. O., Giles, C. B., Wren, J. D., Niedernhofer, L. J., Robbins, P. D. and Kirkland, J. L.
Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of antiapoptotic factors

Previous Winners

2015 Winner:
Steve Horvath, Paolo Garagnani, Maria Giulia Bacalini, Chiara Pirazzini, Stefano Salvioli, Davide Gentilini, Anna Maria Di Blasio, Cristina Giuliani, Spencer Tung, Harry V. Vinters and Claudio Franceschi
Accelerated epigenetic aging in Down syndrome

2015 Runners Up:

Oláhová, M. and Veal, E. A.
A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity

Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., Palmer, A. K., Ikeno, Y., Hubbard, G. B., Lenburg, M., O’Hara, S. P., LaRusso, N. F., Miller, J. D., Roos, C. M., Verzosa, G. C., LeBrasseur, N. K., Wren, J. D., Farr, J. N., Khosla, S., Stout, M. B., McGowan, S. J., Fuhrmann-Stroissnigg, H., Gurkar, A. U., Zhao, J., Colangelo, D., Dorronsoro, A., Ling, Y. Y., Barghouthy, A. S., Navarro, D. C., Sano, T., Robbins, P. D., Niedernhofer, L. J. and Kirkland, J. L.
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs


2014 Winner:
D-F. Dai, P. P. Karunadharma, Y. A. Chiao, N. Basisty, D. Crispin, E. J. Hsieh, T. Chen, H. Gu, D. Djukovic, D. Raftery, R. P. Beyer, M. J. Maccoss, P. S. Rabinovitch
Altered proteome turnover and remodeling by short-term caloric restriction or rapamycin rejuvenate the aging heart

2014 Runners Up:
H. M. Brown-Borg, S. G. Rakoczy, J. A. Wonderlich, L. Rojanathammanee, J. J. Kopchick, V. Armstrong, D.Raasakka
Growth hormone signaling is necessary for lifespan extension by dietary methionine

K. E. Gribble, G. Jarvis, M. Bock, D. B. M. Welch
Maternal caloric restriction partially rescues the deleterious effects of advanced maternal age on offspring



2013 Winner

E. M. Mercken, S. D. Crosby, D. W. Lamming, L. JeBailey, S. Krzysik-Walker, D. T. Villareal, M. Capri, C. Franceschi, Y. Zhang, K. Becker, D.M. Sabatini, R.de Cabo, L. Fontana
Calorie restriction in humans inhibits the P13/AKT pathway and induces a younger transcription profile

2013 Runners Up:
M. De Cecco, S.W. Criscione, E.J.Peckham, S. Hillenmeyer, E.A. Hamm, J.Manivannan, A.L. Peterson, J.A. Kreiling, N. Neretti, J.M.Sedivy
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

A. Tomás-Loba, B.B. de Jesus, J.M. Mato and M.A. Blasco
A metabolic signature predicts biological age in mice

2012 Winner:
Sergiy Libert, Michael S. Bonkowski, Kelli Pointer, Scott D. Pletcher and Leonard Guarente.
Deviation of inate circadian Period from 24 h reduces longevity in mice.

2012 Runners Up:
Louise T. Jensen, Tine H. Møller, Simon A. Larsen, Helle Jakobsen and Anders Olsen.
A new role for laminins as modulators of protein toxicity in Caenorhabditis elegans

Yuli Volovik, Moria Maman, Tatyana Dubnikov, Michal Bejerano-Sagie, Derek Joyce, Erik A Kapernick, Ehud Cohen and Andrew Dillin.
Temporal requirements of heat shock factor-1 for longevity assurance

2011 Winner:
R. K. Minor, M. Lo´ pez, C. M. Younts, B. Jones, K. J. Pearson, R. Michael Anson, C. Die´guez and R. de Cabo.
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction.

2011 Runners Up:
A. A. Tomilov, J. J. Ramsey, K. Hagopian, M. Giorgio, K. M. Kim, A. Lam, E. Migliaccio, K. C. Lloyd, I. Berniakovich, T. A. Prolla, P. Pelicci and G. A. Cortopassi.
The Shc locus regulates insulin signaling and adiposity in mammals

N. M. V. Gomes, O. A. Ryder, M. L. Houck, S. J. Charter, W. Walker, N. R. Forsyth, S. N. Austad, C. Venditti, M. Pagel, J. W. Shay and W. E. Wright.
Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination

2010 Winner:
C-Y. Liao et al.
Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

2010 Runners Up:
S. Liang et al.
Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber)

Y. Kanfi et al.
SIRT6 protects against pathological damage caused by diet-induced obesity

2009 Winner:
A. Matheu et al.
Anti-aging activity of the Ink4/Arf locus

2009 Runners Up:
E. L. Greer and A. Brunet
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans

Rong Yuan et al.
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

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