Clinical Physiology and Functional Imaging

Cover image for Vol. 36 Issue 3

Edited By: Jens Bjoern Bülow

Impact Factor: 1.438

ISI Journal Citation Reports © Ranking: 2014: 66/83 (Physiology)

Online ISSN: 1475-097X

Author Guidelines

Instructions to Authors

Clinical Physiology and Functional Imaging is devoted to clinical and experimental research pertinent to human physiology in health and disease. Papers may include new results obtained experimentally, descriptions of new methods of general importance or new interpretations of existing results. New observations should be clearly and succinctly reported so that the purpose and outcome of the study is meaningful to scientists from a number of disciplines.

It is assumed that all investigations on human subjects described in manuscripts submitted to this journal shall have been conducted according to the principles expressed in the Declaration of Helsinki and approved by an ethics committee on human research.

Clinical Physiology and Functional Imaging employs a plagiarism detection system. By submitting your manuscript to this journal, you accept that your manuscript may be screened for plagiarism against previous published works.


Manuscripts should be submitted online at .  All parts of the manuscript are needed in an electronic format (including figures). A user ID and password can be created at the site. Format the manuscript as described below and, where possible, combine multiple files into a single document. Microsoft Word, rich text format (RTF) and PostScript files and any embedded images will automatically be converted to PDF on upload.

Enquires should be directed to the Editor-in-Chief:

Professor Jens Bjoern Bülow
Department of Biomedical Sciences and Department of Clinical Physiology and Nuclear Medicine
University of Copenhagen & Bispebjerg Hospital
Bispebjerg Hospital
Bispebjerg Bakke 23
2400 Copenhagen NV
Tel: +45 3531 2806

Manuscripts are considered provided that a covering letter is included acknowledging and stating on behalf of all the authors that the work has not been published (except as an abstract, preliminary report or in a thesis) and is not being considered for publication elsewhere.

Manuscripts will be read by the editor and two referees. Acceptance of a manuscript is based on scientific merit and presentation of the material.

All papers submitted to Clinical Physiology & Functional Imaging are accepted on the understanding that they have not been and will not be published elsewhere.

If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions

For authors choosing OnlineOpen

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

Creative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services and Wiley Open Access.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy click here.

Online production tracking is now available for your article through Wiley-Blackwell's Author Services.
Author Services enables authors to track their article - once it has been accpeted - through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mailed at key stages of production. The author will receive an e-mail with a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete e-mail address is provided when submitting the manuscript. Visit Author Services for more details on online production tracking and for a wealth of resources including FAQs and tips on article preparation, submission and more.

Three types of paper are accepted:

1. Full-length papers

These are considered for publication provided that they describe significant, new and carefully confirmed findings and full experimental details are given. There is no limit as to length, but page charges will be applied if the paper exceeds 8 printed pages. Please see the following section for more information on page charges.

2. Short technical communications

These offer the opportunity for more rapid publication of exciting new observations. The manuscript should not occupy more than three journal pages. The author is free to choose a form which is relevant to the nature of the communication.

3. Reviews

Reviews intended to provide perspectives on developing controversial or particularly active areas of research are welcome.

Page Charges
Articles may not exceed 4000 words, not including tables, figures and references. They should contain a maximum of 6 display items in single column width (including figures and tables). Please list the word count and number of display items on the cover page of the manuscript. Manuscripts exceeding these limits will be charged GBP 160 per extra word interval (extra word intervals are 1-700 words (accounts to approximately 1 page), 701-1400 etc.).

Page charges do not apply to Review Articles.

Preparation of papers

1. Style

Manuscripts should be written in English. Spelling should conform to The Concise Oxford Dictionary of Current English, 6th edn.

2. Form

(a) Manuscripts should be typewritten with double spacing and a wide margin (at least 3 cm) on A4 size (206 × 294 mm) paper. Do not use the carriage return (enter) at the end of lines within a paragraph. All pages should be numbered.

(b) Page 1 should include a concise and informative Full title, the names of the authors, the names, e-mail and addresses of the establishments where the work was performed, a Short title not exceeding 60 letters, and details of to whom correspondence and proofs should be sent.

(c) Page 2 should include a Summary not exceeding 250 words and 5-8 keywords not including words in the title of the article.

(d) The following pages should include the sections:

Introduction containing the reasons for doing the work. Exhaustive reviews of the literature should be avoided. No reference to the results obtained should be made.

Methods describing the procedures used in sufficient detail to allow repetition, except for previously published methods.

Results giving concisely the observations made.

Discussion presenting succinctly the authors' interpretations of their findings in relation to previous work.

Acknowledgements of grants and assistance.

Under Acknowledgements please specify contributors to the article other than the authors accredited. Please also include specifications of the source of funding for the study. Suppliers of materials should be named and their location (town, state/county, country) included.

Conflict of Interest

Please include any potential conflict of interests if appropriate.

References in Articles We recommend the use of a tool such as Reference Manager for reference management and formatting. Reference Manager reference styles can be searched for here.

References listed in alphabetical order taking account of the first author. If the first author appears more than once the references should be placed in chronological order. The style to be used is shown in the following examples. In the list of references ALL authors should be presented.

Evilevitch V, Norrgren K, Greiff L, Wollmer P. Microsvascular response in guinea pig skin to histamine challenged with and without application of skin window. Clin Physiol Funct Imaging (2004); 24: 266-269.

Fischman DA. Development of striated muscle. In: The Structure and Function of Muscle (ed. Bourne, G. H.) (1972); vol. 1, part 1, pp. 75-148. Academic Press, New York.

(Journal abbreviations are according to the World List of Scientific Periodicals.)

References to 'personal communications' and 'unpublished work' (e.g., a submitted paper not yet accepted for publication) are permitted in the text only.

In the text references should be quoted giving the author's name and the year of publication in parentheses. For more than two authors, the name of the first author is given followed by 'et al.' If more than one reference is given in the text, they should be placed in chronological order. Examples of the style to be used are: (Welch, 1967; Lin & Nicosia, 1976; Smith et al., 1976).

(e) Tables on separate pages and Figure legends grouped on one page should be at the end of the manuscript. Tables should be supplied with an informative heading and should be comprehensible with minimum reference to the text. In the full-text online edition of the journal, figure legends may be truncated in abbreviated links to the full screen version. Therefore, the first 100 characters of any legend should inform the reader of key aspects of the figure.

(f) Electronic artwork: We would like to receive your artwork in electronic form. Please save vector graphics (e.g. line artwork) in Encapsulated Postscript Format (EPS), and bitmap files (e.g. half-tones) in Tagged Image File Format (TIFF). Ideally, vector graphics that have been saved in metafile (.WMF) or pict (.PCT) format should be embedded within the body of the text file. Detailed information on our digital illustration standards is availabe on Author Services.

We are happy to accept hard copy artwork if you are unable to send it electronically. Each figure should be on a separate page, photographs should be sent as glossy blank and white prints, and any lettering required should appear on the photograph [excluding (a), (b) for parts of figures]. Please give a bar or state magnification where appropriate. The figure number, name of the first author and the short title should be written on the back.

Colour artwork. Colour figures will be published online only for free. If you wish to include colour in the print version of your article, a charge for colour figures will be made. A Colour Work Agreement Form must be filled in for all manuscripts that have been submitted with colour work, even if you subsequently choose not to publish either in print or online in colour. Therefore, please note that if there is colour artwork in your manuscript when it is accepted for publication, John Wiley & Sons Ltd requires you to complete and return a colour work agreement form before your paper can be published. The form can be downloaded here: Colour Work Agreement

Any article received by Wiley with colour work will not be published until the form has been returned.

(g) Footnotes to the text should be used sparingly and their locations should be indicated by superscript numbers. They should be typed with corresponding numbers on a separate sheet. In tables, reference to footnotes should be made using the symbols †, ‡, §, ††, in that order.

3. Symbols, units, abbreviations

(a) Symbols for physical units should be those of the Systeme Internationale (SI) Units. These are described in Quantities, Units and Symbols, 3rd edn. (1977). The Royal Society of Medicine, London. More familiar units may be allowed in parentheses if this facilitates the comprehension of the paper. For example, either 133.3 Pa or 133.3 Pa (1 mmHg) is permissible, but 1 mmHg alone is not, except for blood pressure which should be in mmHg. The symbol for the plural of a unit is the same as for the singular.

(b) Abbreviations will not be permitted unless their use is universally accepted. The Instructions to Authors of the Biochemical Journal provides a useful guide and further details of permissible abbreviations may be obtained from the Editor.

(c) Chemical and biochemical nomenclature should follow the Recommendations of the IUPAC-IUB Commission on Nomenclature. Details of these can be obtained in various volumes of the Biochemical Journal as outlined in Instructions to Authors or from Waldo E. Cohn, Director, NRC Office of Biochemical Nomenclature, Oak Ridge National Laboratory, Box Y, Oak Ridge, TN 37830, USA.

(d) Enzymes, when first mentioned, should be written in full followed by the IUB Enzyme Commission (EC) number; approved trivial names may be subsequently used. Details of these may be obtained from the latest edition of Enzyme Nomenclature, Elsevier Publishing Co., Amsterdam.

(e) Solutions should be described in terms of molarity and use the decimal system which should be written as 1.5 mmol/l glucose, for example. In expressing the concentration of a substance in physiological fluids molarity is preferred to % or wt/vol. The SI system recommends that 'M' should be replaced by 'mol/l' and that '% (v/v)' and '% (w/v)' should be expressed as for example 'ml/l' and 'g/l'. Sufficient detail of buffer composition should be provided to enable its preparation.

(f) The name of drugs used should be the approved trivial name and when first mentioned also the full chemical name. Trade names or common names may be given in parentheses when the drug is first mentioned.

4. Statistics

The authors should use appropriate statistics to analyse their results. The statistical methods used should be stated under Methods. The following data should be presented: (1) the number of independent experiments; (2) the value of the mean; (3) the standard deviation (SD) or the standard error of the mean (SEM).

5. Human experiments

Work on humans that is submitted to the Journal should comply with the principles of the Declarations of Helsinki (1964) British Medical Journal (1964) ii, 177-178. The manuscript should contain a statement that the work has been approved by the Ethics Committee of the Institution in which it was performed and if subjects gave informed consent to participate. The editors reserve the right to reject papers in which, in their opinion, the ethical justification is questionable.

The corresponding author will receive an e-mail alert containing a link to a web site. A working e-mail address must therefore be provided for the corresponding author. The proof can be downloaded as a PDF* (portable document format) file from this site. This will enable the file to be opened, read on screen and printed out in order for any corrections to be added. Further instructions will be sent with the proof.

NEW: Early View
Clinical Physiology and Functional Imaging is covered by Wiley-Blackwell's Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Articles are therefore available as soon as they are ready, rather than having to wait for the next scheduled print issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so Early View articles cannot be cited in the traditional way. They are therefore given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before it is allocated to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article.

OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. For the full list of terms and conditions, see

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from at our webpage Author Services.

Prior to acceptance there is no requirement to inform the Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

The corresponding author will receive a pdf 'reprint' of his or her article. Printed offprints can be supplied if ordered on the offprint form which will accompany the proofs.

* To read PDF files, you must have Acrobat Reader installed on your computer. If you do not have this program, this is available as a free download from Adobe.

Author Material Archive Policy: Please note that unless specifically requested, Wiley-Blackwell will dispose of all hardcopy or electronic material submitted 2 published issues after publication.  If you require the return of any material submitted, please inform the editorial office or production editor as soon as possible if you have not yet done so.