British Journal of Pharmacology

Cover image for Vol. 174 Issue 3

Editor-in-Chief: Professor A. Ahluwalia

Impact Factor: 5.259

ISI Journal Citation Reports © Ranking: 2015: 17/255 (Pharmacology & Pharmacy)

Online ISSN: 1476-5381

Associated Title(s): British Journal of Clinical Pharmacology, Pharmacology Research & Perspectives

Reviews


2017

The SPARC protein: an overview of its role in lung cancer and pulmonary fibrosis and its potential role in chronic airways disease
Sharon L I Wong and Maria B Sukkar

2016

Understanding how long-acting β2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma – an update
Robert Newton and Mark A Giembycz

Snapshot: implications for melatonin in endoplasmic reticulum homeostasis
Wei Hu, Zhiqiang Ma, Shouyin Di, Shuai Jiang, Yue Li, Chongxi Fan, Yang Yang and Dongjin Wang

The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease
James C Evans, Meenakshi Malhotra, John F Cryan and Caitriona M O'Driscoll

Identifying ligands at orphan GPCRs: current status using structure-based approaches
Tony Ngo, Irina Kufareva, James LJ Coleman, Robert M Graham, Ruben Abagyan and Nicola J Smith

Protease-activated receptor 4: from structure to function and back again
Shauna L French and Justin R Hamilton

Sarcolemmal dependence of cardiac protection and stress-resistance: roles in aged or diseased hearts
Louise E See Hoe, Lauren T May, John P Headrick and Jason N Peart

Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling
PJ Little, MD Hollenberg, D Kamato, W Thomas, J Chen, T Wang, W Zheng and N Osman

Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus bias
K Sengmany and K J Gregory

Superagonism at G protein-coupled receptors and beyond
R Schrage, A De Min, K Hochheiser, E Kostenis and K Mohr

Fluorescence- and bioluminescence-based approaches to study GPCR ligand binding
Leigh A Stoddart, Carl W White, Kim Nguyen, Stephen J Hill and Kevin D G Pfleger

Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer
Monika Wierdl, Lyudmila Tsurkan, M Jason Hatfield and Philip M Potter

Mitochondrial dysfunction in inflammatory responses and cellular sensecence: pathogenesis and pharmacological targets for chronic lung diseases
Li Yue and Hongwei Yao

Obestatin as a key regulator of metabolism and cardiovascular function with emerging therapeutic potential for diabetes
Elaine Cowan, Kerry J Burch, Brian D Green and David J Grieve

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
Ambra A Grolla, Cristina Travelli, Armando A Genazzani and Jaswinder K Sethi

GPCRdb: the G protein-coupled receptor database – an introduction
C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, A S Hauser, P Kolb, A J Bojarski, G Vriend and D E Gloriam

Cannabinoid–dopamine interactions in the physiology and physiopathology of the basal ganglia
Concepción García, Cristina Palomo-Garo, Yolanda Gómez-Gálvez and Javier Fernández-Ruiz

Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and β-amyloid in ageing and Alzheimer's disease
Orly Weinreb, Tamar Amit, Orit Bar-Am and Moussa B H Youdim

Amylin structure–function relationships and receptor pharmacology: implications for amylin mimetic drug development
Rebekah L Bower and Debbie L Hay

An update on PPAR activation by cannabinoids
Saoirse Elizabeth O'Sullivan

Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm
Brodie L Loudon, Hannah Noordali, Nicholas D Gollop, Michael P Frenneaux and Melanie Madhani

Possible role for anisodamine in organophosphate poisoning
Arik Eisenkraft and Avshalom Falk

Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18
Silvia Carvalho, Francesca Levi-Schaffer, Michael Sela and Yosef Yarden

Adrenaline: insights into its metabolic roles in hypoglycaemia and diabetes
A J M Verberne, W S Korim, A Sabetghadam and I J Llewellyn-Smith

Identification of A3 adenosine receptor agonists as novel non-narcotic analgesics
K Janes, AM Symons-Liguori, K A Jacobson and D Salvemini

On the different experimental manifestations of two-state ‘induced-fit’ binding of drugs to their cellular targets
Georges Vauquelin, Isabelle Van Liefde and David C Swinney

Role of the endocannabinoid system in diabetes and diabetic complications
G Gruden, F Barutta, G Kunos and P Pacher

Effects of P2Y12 receptor antagonists beyond platelet inhibition – comparison of ticagrelor with thienopyridines
Sven Nylander and Rainer Schulz

What is the evidence for the role of TRP channels in inflammatory and immune cells?
A Parenti, F De Logu, P Geppetti and S Benemei

The Warburg effect and drug resistance
Bhaskar Bhattacharya, Mohd Feroz Mohd Omar and Richie Soong

Monoclonal antibodies: the new magic bullets for allergy: IUPHAR Review 17
N Landolina and F Levi-Schaffer

Immunoinflammatory Diseases Of The Central Nervous System - The Tale Of Two Cytokines
M J Hofer And I L Campbell

The Contribution Of Astrocytes And Microglia To Traumatic Brain Injury
Ila P Karve, Juliet M Taylor And Peter J Crack

Microglial M1/M2 Polarization And Metabolic States
Ruben Orihuela, Christopher A McPherson and Gaylia Jean Harry

Inflammation In Acute Cns Injury: A Focus On The Role Of Substance P
F Corrigan, R Vink and R J Turner

Microglial Activation And Progressive Brain Changes In Schizophrenia
L E Laskaris, M A Di Biase, I Everall, G Chana, A Christopoulos, E Skafidas, V L Cropley and C Pantelis

Progressive Inflammation-Mediated Neurodegeneration After Traumatic Brain Or Spinal Cord Injury
Alan I Faden, Junfang Wu, Bogdan A Stoica and David J Loane

COPD And Squamous Cell Lung Cancer: Aberrant Inflammation And Immunity Is The Common Link
Steven Bozinovski, Ross Vlahos, Desiree Anthony, Jonathan McQualter, Gary Anderson, Louis Irving and Daniel Steinfort

Optical Probes Based On G Protein-Coupled Receptors - Added Work Or Added Value?
A D Stumpf and C Hoffmann

Molecular Switches Under Tgf Signalling During Progression From Cardiac Hypertrophy To Heart Failure
J Heger, R Schulz and G Euler

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