Cover image for Vol. 22 Issue 5

Edited By: Editor-in-Chief: David Y Graham and Assistant Editor: Francis Megraud

Impact Factor: 3.429

ISI Journal Citation Reports © Ranking: 2016: 27/79 (Gastroenterology & Hepatology); 37/124 (Microbiology)

Online ISSN: 1523-5378

Author Guidelines

Helicobacter recognises the critical role that has been established for Helicobacter pylori in peptic ulcer, gastric adrenocarcinoma, and primary gastric lymphoma. New Helicobacter species are regularly discovered.

Helicobacter will publish, first and foremost, primary research in a wide range of experimental, scientific and clinical areas including: bacterial physiology, molecular biology, epidemiology, animal models, pathogenesis, immune response, histopathology, gastric cancer, paediatrics, vaccines, diagnosis, and therapy. Manuscripts related to non-Helicobacter pylori species are also welcome.

Effective from the 2011 volume, Helicobacter will be published in an online-only format.


The journal's ethical policies are outlined in the separate document Ethical Policies of Helicobacter. Published work must comply with these policies in full.

Authors of accepted papers must complete and return the following Ethics-related documents:

·       Conflict of Interest Form (Copyright transfer is a condition of publication, and papers will not be passed to the publisher for production unless copyright has been transferred.)

·       A statement comprising full disclosure of competing financial and other interests from all authors.

·       Full statements on consent, where relevant.

·       Clinical trial registration number, name and URL of the trial register, where relevant.

·       Permission details on reproduction of figures or legends, where relevant.


Authors of accepted articles are liable to pay page charges, and authors must complete the Page Charges Form. Helicobacter does not make the payment of page charges an absolute condition for acceptance of a manuscript for publication, however. Authors will be charged once their article is published in an issue. These charges are not related to those for open access publishing in our OnlineOpen programme (see below).


Manuscripts should be submitted online, through ScholarOne Manuscripts (formerly known as Manuscript Central), at http://mc.manuscriptcentral.com/hel.
Enquiries on submissions should be addressed to the Editorial Office.

For guidance on how to submit articles to biomedical journals, please see Uniform Requirement for Manuscripts Submitted to Biomedical Journals, available from the International Committee of Medical Journal Editors.

Submission is considered on the condition that papers are previously unpublished, are not offered simultaneously elsewhere, that all authors (defined below) have read and approved the content, that all authors have declared all competing interests and the work has been conducted under internationally accepted ethical standards after relevant ethical review. Accepted manuscripts become the sole property of Helicobacter and may not be published elsewhere without consent from the publisher.

All articles are subject to review by experienced referees. The Editor and Editorial Board judge manuscripts suitable for publication, and decisions by the Editor are final.

Material accepted for publication is copyedited and typeset. An email alert is sent to the corresponding author to download e-proofs for final review. The corresponding author is responsible for the entire content of the copyedited article. Extensive changes to the proofs will be charged to the contributors and could delay publication.

Manuscripts will be considered for publication in the form of original articles, reviews, descriptions of techniques, brief communications, and letters. We accept only outstanding Case Reports.

Case Reports and Clinical Case Reports

We work together with Wiley’s open access journal, Clinical Case Reports, to enable rapid publication of good quality case reports that we are unable to accept for publication in our journal. Authors of case reports rejected by our journal will be offered the option of having their case report, along with any related peer reviews, automatically transferred for consideration by the Clinical Case Reports editorial team. Authors will not need to reformat or rewrite their manuscript at this stage, and publication decisions will be made a short time after the transfer takes place. Clinical Case Reports will consider case reports from every clinical discipline and may include clinical images or clinical videos. Clinical Case Reports is an open access journal, and article publication fees apply. For more information please go to www.clinicalcasesjournal.com.


Authors of accepted articles must complete a copyright or licence form. On acceptance the author identified as the formal corresponding author for the paper will receive an email prompting them to login into Author Services; where via the Wiley Author Licensing Service (WALS) they will be able to complete the licence agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement
If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreemen(CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions http://authorservices.wiley.com/bauthor/faqs_copyright.asp

For authors choosing OnlineOpen
If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

Creative Commons Attribution License OAA

reative Commons Attribution Non-Commercial License OAA

Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://authorservices.wiley.com/bauthor/faqs_copyright.asp and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK) you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal's compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement.


Original manuscripts should be a maximum of 5,000 words (not including references, tables and figures). Manuscripts should include a maximum of 6 Figures and/or tables. Additional tables or figures and/or extra methodological detail can be included in a separate Supplementary Appendix. The production and handling Editors may relocate tables or figures into a Supplementary Appendix prior to the production of page proofs if the manuscript exceeds these specifications at the time of final acceptance.

Digital artwork
The Publisher's website provides guidance on the preparation and submission of figures, links to useful websites and access to both the Wiley house and journal specific style guides:
http://authorservices.wiley.com/bauthor/illustration.asp. Figures and tables must be submitted via Scholar One Manuscripts as individual images in one of the recommended formats. Figure and table legends must be able to stand alone in the text.

Authors should observe the following guidelines.

1. Do not attempt to make your output approximate or match the typeset page.

2. Be consistent in style (i.e. units, abbreviations). (See note about abbreviations below.)

3. End paragraphs in a uniform manner, and in a different manner from line endings within paragraphs. A frequently used paragraph ending is simply two carriage returns.

4. Use '1', not 'el' for 'one'. Do not use 'oh' for zero.

5. Use double spacing in your document. Do not add extra line spacing (except as a normal paragraph ending indication) above or below titles, subheads, or between paragraphs.

6. Avoid using multiple spaces (horizontal) in your electronic manuscript. End sentences with only one space. Never use multiple spaces for horizontal positioning of text.

7. Tables and figure captions should be prepared in separate files. The copyeditor will indicate the placement of this material within the text.

8. Do not divide words by hyphenating at line endings.

9. See reference style guide below. Do not attempt to incorporate small capital letters when typing authors' names.

Title page
The first text page should contain
1. Title
2. Running title (of no more than 45 characters, including spaces).
3. Full names and affiliations for all authors;
4. Full current postal and e-mail address for the corresponding author, to whom email notification to download the e-proofs will be sent, including also telephone and fax numbers for that person.

Abbreviations should not be used in the abstract, and, with the exception of standard abbreviations, should not be used within the manuscript. As a general rule, abbreviations do not improve reader comprehension and should be avoided.

The abstract should not exceed 250 words and must be structured in four separate sections headed Background, Materials and Methods, Results, and Conclusions. The abstract should state clearly the relevance of the work to human disease.

Your manuscript should be submitted as one text file in either Word document (.doc), (.docx) or RTF (.rtf). Please do not submit your file as a PDF. The text of the manuscript should be in the following sequence:
Acknowledgements and disclosures

Tables and figure legends should then follow. Type footnotes (double-spaced) on the bottom of the page on which they are mentioned. Cite all tables and figures in the text, numbering them sequentially as they are cited.

Tables should follow the Reference section, should be typed double-spaced on separate sheets and numbered consecutively within the text. Tables and text should not duplicate each other. If possible, hold tables to one standard manuscript page; if the table continues past one page, repeat all heads and the stub (left-hand column). Explain all abbreviations in a footnote. Provide a number and title for each table.

Please see http://authorservices.com/bauthor/illustration.asp for guidance on acceptable file formats for figures.

You must upload high-resolution files. Bitmap files (e.g. photographs) should be supplied as TIFF (.tif) files. Labelled micrographs (combination) or charts/ graphs/diagrams (line) can be supplied as a TIFF or EPS (.eps) format. Line art must be scanned at a minimum of 800 dpi; photographs at a minimum of 300 dpi.

Figures for review must be uploaded separately and conform to the same standards as the figures for publication. They should not be embedded into the text of your initial submission. Colour figures that significantly enhance the article will be considered for publication.

All illustrations should be able to be reduced to 50-66% of their original size with no loss of clarity or legibility. For photographs of recognisable persons, submit a signed release form from the patient authorising publication. Photomicrographs must have internal scale markers.

Figure legends
Each figure must have a corresponding legend, which must be numbered with an Arabic number to correspond to the illustration as it appears in the text. Explain all symbols, arrows numbers, or letters used in the figure and provide information on scale and/or magnification. For photomicrographs, include information on scale and/or magnification. For photomicrographs, include information on the method of staining. Cite each figure in the text by its number. Figures should be numbered consecutively as they appear in the text. If a figure has been previously published, permission must be received in writing for its use regardless of authorship or publisher. Acknowledgement of the original source must be included in the legend.

All references should be numbered consecutively in order of appearance and should be as complete as possible. In text citations should cite references in consecutive order using Arabic superscript numerals. Sample references follow:

Journal article:
1. King VM, Armstrong DM, Apps R, Trott JR. Numerical aspects of pontine, lateral reticular, and inferior olivary projections to two paravermal cortical zones of the cat cerebellum. J Comp Neurol 1998; 390: 537-551.

2. Voet D, Voet JG. Biochemistry. New York: John Wiley & Sons; 1990. 1223 p.

Chapter in book
3. Solensky R. Drug allergy: desensitization and treatment of reactions to antibiotics and aspirin. In: Lockey P, ed. Allergens and Allergen Immunotherapy. 3rd ed. New York, NY: Marcel Dekker; 2004:585-606.

4. Outbreak notice: Cholera in Haiti. Centers for Disease Control and Prevention Web site. http://wwwnc.cdc.gov/travel/notices/outbreak- notice/haiti-cholera.htm Published October 22, 2010. Updated January 9, 2012. Accessed February 1, 2012.

Please note that journal title abbreviations should conform to the practices of Chemical Abstracts.

For more information about AMA reference style - AMA Manual of Style.

Acknowledgments and disclosures
The Journal insists on full disclosure of competing financial and other interests from all authors (see above). All authors much complete and sign a Conflict of Interests form. At the end of the acknowledgements section, there must be a statement of these interests. In the absence of such, please include the following statement: 'Competing interests: the authors have no competing interests.'

Letters to the Editor
Letters to the Editor should be no more than three pages, comprising up to six references and one table or figure.

Supporting Information
Supporting Information can be a useful way for an author to include important but ancillary information with the online version of an article. Examples of Supporting Information include additional tables, data sets, figures, movie files, audio clips, 3D structures, and other related nonessential multimedia files. Supporting Information should be cited within the article text, and a descriptive legend should be included. It is published as supplied by the author, and a proof is not made available prior to publication; for these reasons, authors should provide any Supporting Information in the desired final format. For further information on recommended file types and requirements for submission, please visit: https://authorservices.wiley.com/author-resources/Journal-Authors/Prepare/manuscript-preparation-guidelines.html/supporting-information.html

General style points
Give all measurements in metric units. Use generic names of drugs. Adhere to acceptable English usage and syntax; avoid jargon, euphemistic phrasing, and obscure terms and abbreviations. For abbreviations, follow the Council of Biology Editors Style Manual available from the Council of Biology Editors, Inc., 11 South LaSalle Street, Suite 1400, Chicago, IL 60603. (Also DHEW Publications No. (NIH)80-267; ISSN 0093-3821.)

Credits and permissions
In addition to the notice of informed consent and releases to publish photographs of recognisable persons, submit with the manuscript written permission to use non-original material (quotations exceeding 100 words, any table or figure) from both author and publisher of the original. Credit the source in a text or table footnote or at the end of a figure legend.

Pre-submission English-language editing
Authors for whom English is a second language may choose to have their manuscript professionally edited before submission to improve the English. A list of independent suppliers of editing services can be found at http://authorservices.wiley.com/bauthor/english_language.asp. All services are paid for and arranged by the author, and use of one of these services does not guarantee acceptance or preference for publication.


Tracking articles
Wiley's Author Services enables authors to track their article - once it has been accepted - through the production process to publication online and in print. Authors can check the status of their articles online and choose to receive automated e-mails at key stages of production, removing the need to contact the production editor to check on progress. The corresponding author will receive a unique link that enables them to register and have their article automatically added to the system. Please ensure that a complete email address is supplied.

Visit http://authorservices.wiley.com/bauthor/ for more details on online production tracking and for a wealth of resources, including FAQs (frequently asked questions) and tips on article preparation, submission and more.

The Editor will not check the typeset proofs of manuscripts for errors, thus it is the responsibility of the author of each paper to review page proofs carefully for accuracy of citations, formulas, etc., and to check for omissions in the text.

Proofs are made available to corresponding authors as a PDF, downloadable from our e-proofing website. Full instructions will be sent via email notification when the proof is ready for collection. Adobe Acrobat Reader is required in order to read this file. This can be downloaded (free of charge) from http://www.adobe.com/products/acrobat/readermain.html.
In your absence, please arrange a named colleague to correct on your behalf. Major alterations will be charged to the author and delay publication.

Author must review the proofs carefully and return them to the Helicobacter Production Editor within 48 hours of receipt. Late return will cause delay in publication.

PDF offprint and reprints
Corresponding authors can retrieve a free PDF offprint by registering with Wiley's Author Services facility (http://authorservices.wiley. com/bauthor/register.asp). Reprints of the printed published article may be purchased if ordered via the method stipulated on the instructions that will accompany the proofs.

Archiving policy
Unless specifically requested at submission, the publisher will dispose of all material submitted two months post-publication.

This journal now uses eLocators. eLocators are unique identifiers for an article that service the same function page numbers traditionally served in the print world. When citing this article, please insert the eLocator in place of the page number. For more information, please visit the Author Services eLocator page here.

Online Open and open access publishing
OnlineOpen is available to authors of primary research articles who wish to make their article available to non-subscribers on publication, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. See the full list of terms and conditions. Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website here. Prior to acceptance, there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

Early View publication
Helicobacter is covered by Wiley's Early View service. Early View articles are complete full-text articles published online in advance of their publication in a printed issue. Articles are therefore available as soon as they are ready, rather than having to wait for the next scheduled print issue. Early View articles are complete and final. They have been fully reviewed, revised and edited for publication, and the authors' final corrections have been incorporated. Because they are in final form, no changes can be made after online publication. The nature of Early View articles means that they do not yet have volume, issue or page numbers, so Early View articles cannot be cited in the traditional way. They are therefore given a Digital Object Identifier (DOI), which allows the article to be cited and tracked before it is allocated to an issue. After print publication, the DOI remains valid and can continue to be used to cite and access the article.

Research funded by the NIH, the Wellcome Trust and the Howard Hughes Medical Institute
Wiley complies with all current open access funding mandates.
Pursuant to NIH mandate, Wiley will post the accepted version of contributions authored by NIH grant-holders to PubMed Central upon acceptance. This accepted version will be made publicly available 12 months after publication. For further information, see www.wiley.com/go/nihmandate. Please see http://authorservices.wiley.com/bauthor/CTA.asp for further
details on research funded by the Wellcome Trust and the Howard Hughes Medical Institute.