Cover image for Vol. 58 Issue 7

Early View (Online Version of Record published before inclusion in an issue)

Edited By: Astrid Nehlig, PhD, Michael Sperling, MD. and Gary W. Mathern, MD.

Impact Factor: 5.295

ISI Journal Citation Reports © Ranking: 2016: 21/194 (Clinical Neurology)

Online ISSN: 1528-1167


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  1. Full-Length Original Research

    1. You have full text access to this OnlineOpen article
      Voxel-based magnetic resonance image postprocessing in epilepsy

      Pascal Martin, Gavin P. Winston, Philippa Bartlett, Jane de Tisi, John S. Duncan and Niels K. Focke

      Version of Record online: 26 JUL 2017 | DOI: 10.1111/epi.13851

  2. Brief Communication

    1. You have full text access to this OnlineOpen article
      Phenomenological network models: Lessons for epilepsy surgery

      Jurgen Hebbink, Hil Meijer, Geertjan Huiskamp, Stephan van Gils and Frans Leijten

      Version of Record online: 26 JUL 2017 | DOI: 10.1111/epi.13861

  3. Full-Length Original Research

    1. Antiepileptic drug discontinuation by people with epilepsy in the general population

      Giorgia Giussani, Elisa Bianchi, Valentina Canelli, Giuseppe Erba, Carlotta Franchi, Alessandro Nobili, Josemir W. Sander, Ettore Beghi and for the EPIRES Group

      Version of Record online: 26 JUL 2017 | DOI: 10.1111/epi.13853

    2. Seizure outcome after hippocampal deep brain stimulation in patients with refractory temporal lobe epilepsy: A prospective, controlled, randomized, double-blind study

      Arthur Cukiert, Cristine Mella Cukiert, Jose Augusto Burattini, Pedro Paulo Mariani and Daniela Fontes Bezerra

      Version of Record online: 26 JUL 2017 | DOI: 10.1111/epi.13860

    3. Health care resource utilization before and after perampanel initiation among patients with epilepsy in the United States

      Edward Faught, François Laliberté, Zhixiao Wang, Victoria Barghout, Batool Haider, Dominique Lejeune, Guillaume Germain, Jiyoon Choi, Aneesha Wagh and Mei Sheng Duh

      Version of Record online: 25 JUL 2017 | DOI: 10.1111/epi.13857

    4. Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy

      Mariana Alves, Rosa Gomez-Villafuertes, Norman Delanty, Michael A. Farrell, Donncha F. O'Brien, Maria Teresa Miras-Portugal, Miguel Diaz Hernandez, David C. Henshall and Tobias Engel

      Version of Record online: 21 JUL 2017 | DOI: 10.1111/epi.13850

    5. Decreased levels of active uPA and KLK8 assessed by [111In]MICA-401 binding correlate with the seizure burden in an animal model of temporal lobe epilepsy

      Stephan Missault, Lore Peeters, Halima Amhaoul, David Thomae, Annemie Van Eetveldt, Barbara Favier, Anagha Thakur, Jeroen Van Soom, Asla Pitkänen, Koen Augustyns, Jurgen Joossens, Steven Staelens and Stefanie Dedeurwaerdere

      Version of Record online: 19 JUL 2017 | DOI: 10.1111/epi.13845

    6. Altered metabolomic–genomic signature: A potential noninvasive biomarker of epilepsy

      Helen C. Wu, Fabien Dachet, Farhad Ghoddoussi, Shruti Bagla, Darren Fuerst, Jeffrey A. Stanley, Matthew P. Galloway and Jeffrey A. Loeb

      Version of Record online: 17 JUL 2017 | DOI: 10.1111/epi.13848

  4. Brief Communication

    1. Nocturnal seizures are associated with more severe hypoxemia and increased risk of postictal generalized EEG suppression

      Véronique Latreille, Myriam Abdennadher, Barbara A. Dworetzky, Judith Ramel, David White, Eliot Katz, Marcin Zarowski, Sanjeev Kothare and Milena Pavlova

      Version of Record online: 17 JUL 2017 | DOI: 10.1111/epi.13841

  5. Brief Communications

    1. Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice

      Shijie Liu, Yu Shen, Sandy R. Shultz, Anne Nguyen, Christopher Hovens, Paul A. Adlard, Ashley I. Bush, Jianxiong Chan, Patrick Kwan, Terence J. O'Brien and Nigel C. Jones

      Version of Record online: 15 JUL 2017 | DOI: 10.1111/epi.13847

  6. Full-Length Original Research

    1. Predictors of cognitive function in patients with hypothalamic hamartoma following stereotactic radiofrequency thermocoagulation surgery

      Masaki Sonoda, Hiroshi Masuda, Hiroshi Shirozu, Yosuke Ito, Kohei Akazawa, Eishi Asano and Shigeki Kameyama

      Version of Record online: 13 JUL 2017 | DOI: 10.1111/epi.13838

    2. You have full text access to this OnlineOpen article
      Automated T2 relaxometry of the hippocampus for temporal lobe epilepsy

      Gavin P. Winston, Sjoerd B. Vos, Jane L. Burdett, M. Jorge Cardoso, Sebastien Ourselin and John S. Duncan

      Version of Record online: 12 JUL 2017 | DOI: 10.1111/epi.13843

  7. Brief Communications

    1. Anion gap can differentiate between psychogenic and epileptic seizures in the emergency setting

      Yi Li, Liesl Matzka, Louise Maranda and Daniel Weber

      Version of Record online: 11 JUL 2017 | DOI: 10.1111/epi.13840

  8. Full-Length Original Research

    1. Anticonvulsant effect of cannabinoid receptor agonists in models of seizures in developing rats

      Megan N. Huizenga, Evan Wicker, Veronica C. Beck and Patrick A. Forcelli

      Version of Record online: 10 JUL 2017 | DOI: 10.1111/epi.13842

    2. Mortality with brainstem seizures from focal 4-aminopyridine–induced recurrent hippocampal seizures

      Muhammad Tariqus Salam, Gaspard Montandon, Roman Genov, Orrin Devinsky, Martin Del Campo and Peter L. Carlen

      Version of Record online: 10 JUL 2017 | DOI: 10.1111/epi.13846

    3. Effect of vigabatrin on seizure control and safety profile in different subgroups of children with epilepsy

      Michele C. Jackson, Saba Jafarpour, Jacquelyn Klehm, Sigride Thome-Souza, Francesca Coughlin, Kush Kapur and Tobias Loddenkemper

      Version of Record online: 10 JUL 2017 | DOI: 10.1111/epi.13836

    4. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet

      Aziza Khabbush, Michael Orford, Yi-Chen Tsai, Tricia Rutherford, Maura O'Donnell, Simon Eaton and Simon J. R. Heales

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13833

    5. Costs, length of stay, and mortality of super-refractory status epilepticus: A population-based study from Germany

      Adam Strzelczyk, Sonja Ansorge, Jana Hapfelmeier, Vijayveer Bonthapally, M. Haim Erder and Felix Rosenow

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13837

  9. Critical Review and Invited Commentary

    1. Epilepsy: Transition from pediatric to adult care. Recommendations of the Ontario epilepsy implementation task force

      Danielle M. Andrade, Anne S. Bassett, Eduard Bercovici, Felippe Borlot, Esther Bui, Peter Camfield, Guida Quaglia Clozza, Eyal Cohen, Timothy Gofine, Lisa Graves, Jon Greenaway, Beverly Guttman, Maya Guttman-Slater, Ayman Hassan, Megan Henze, Miriam Kaufman, Bernard Lawless, Hannah Lee, Lezlee Lindzon, Lysa Boissé Lomax, Mary Pat McAndrews, Dolly Menna-Dack, Berge A. Minassian, Janice Mulligan, Rima Nabbout, Tracy Nejm, Mary Secco, Laurene Sellers, Michelle Shapiro, Marie Slegr, Rosie Smith, Peter Szatmari, Leeping Tao, Anastasia Vogt, Sharon Whiting and O. Carter Snead III

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13832

    2. Update on the mechanisms and roles of high-frequency oscillations in seizures and epileptic disorders

      Premysl Jiruska, Catalina Alvarado-Rojas, Catherine A. Schevon, Richard Staba, William Stacey, Fabrice Wendling and Massimo Avoli

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13830

  10. Full-Length Original Research

    1. Prevalence and outcome of late-onset seizures due to autoimmune etiology: A prospective observational population-based cohort study

      Felix von Podewils, Marie Suesse, Julia Geithner, Bernadette Gaida, Zhong I. Wang, Julia Lange, Alexander Dressel, Matthias Grothe, Christof Kessler, Soenke Langner, Uwe Runge and Christian G. Bien

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13834

  11. Brief Communications

    1. Risk of angioedema associated with levetiracetam compared with phenytoin: Findings of the observational health data sciences and informatics research network

      Jon D. Duke, Patrick B. Ryan, Marc A. Suchard, George Hripcsak, Peng Jin, Christian Reich, Marie-Sophie Schwalm, Yuriy Khoma, Yonghui Wu, Hua Xu, Nigam H. Shah, Juan M. Banda and Martijn J. Schuemie

      Version of Record online: 6 JUL 2017 | DOI: 10.1111/epi.13828

  12. Full-Length Original Research

    1. Seizure-associated aphasia has good lateralizing but poor localizing significance

      Anna Mira Loesch, Hannah Steger, Claudia Losher, Elisabeth Hartl, Jan Rémi, Christian Vollmar and Soheyl Noachtar

      Version of Record online: 4 JUL 2017 | DOI: 10.1111/epi.13835

  13. Critical Review and Invited Commentary

    1. High-frequency oscillations: The state of clinical research

      Birgit Frauscher, Fabrice Bartolomei, Katsuhiro Kobayashi, Jan Cimbalnik, Maryse A. van ‘t Klooster, Stefan Rampp, Hiroshi Otsubo, Yvonne Höller, Joyce Y. Wu, Eishi Asano, Jerome Engel Jr., Philippe Kahane, Julia Jacobs and Jean Gotman

      Version of Record online: 30 JUN 2017 | DOI: 10.1111/epi.13829

  14. Full-Length Original Research

    1. Predictive factors of long-term outcomes of surgery for mesial temporal lobe epilepsy associated with hippocampal sclerosis

      Bertrand Mathon, Franck Bielle, Séverine Samson, Odile Plaisant, Sophie Dupont, Anne Bertrand, Richard Miles, Vi-Huong Nguyen-Michel, Virginie Lambrecq, Ana Laura Calderon-Garcidueñas, Charles Duyckaerts, Alexandre Carpentier, Michel Baulac, Philippe Cornu, Claude Adam, Stéphane Clemenceau and Vincent Navarro

      Version of Record online: 28 JUN 2017 | DOI: 10.1111/epi.13831

    2. Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway

      Diede W. M. Broekaart, Jackelien van Scheppingen, Karlijne W. Geijtenbeek, Mark R. J. Zuidberg, Jasper J. Anink, Johannes C. Baayen, Angelika Mühlebner, Eleonora Aronica, Jan A. Gorter and Erwin A. van Vliet

      Version of Record online: 23 JUN 2017 | DOI: 10.1111/epi.13823

    3. Perisylvian, including insular, childhood epilepsy: Presurgical workup and surgical outcome

      Elena Freri, Sara Matricardi, Francesca Gozzo, Massimo Cossu, Tiziana Granata and Laura Tassi

      Version of Record online: 23 JUN 2017 | DOI: 10.1111/epi.13816

  15. Brief Communication

    1. Regulation of kindling epileptogenesis by hippocampal Toll-like receptors 2

      Jesús-Servando Medel-Matus, Ashley Reynolds, Don Shin, Raman Sankar and Andrey Mazarati

      Version of Record online: 20 JUN 2017 | DOI: 10.1111/epi.13826

  16. Full-Length Original Research

    1. Photosensitivity is an early marker of neuronal ceroid lipofuscinosis type 2 disease

      Nicola Specchio, Marcello Bellusci, Nicola Pietrafusa, Marina Trivisano, Luca de Palma and Federico Vigevano

      Version of Record online: 20 JUN 2017 | DOI: 10.1111/epi.13820

  17. Critical Review and Invited Commentary

    1. Postictal hypoperfusion/hypoxia provides the foundation for a unified theory of seizure-induced brain abnormalities and behavioral dysfunction

      Jordan S. Farrell, Roberto Colangeli, Marshal D. Wolff, Alexandra K. Wall, Thomas J. Phillips, Antis George, Paolo Federico and G. Campbell Teskey

      Version of Record online: 20 JUN 2017 | DOI: 10.1111/epi.13827

    2. How to record high-frequency oscillations in epilepsy: A practical guideline

      Maeike Zijlmans, Gregory A. Worrell, Matthias Dümpelmann, Thomas Stieglitz, Andrei Barborica, Marcel Heers, Akio Ikeda, Naotaka Usui and Michel Le Van Quyen

      Version of Record online: 16 JUN 2017 | DOI: 10.1111/epi.13814

  18. Full-Length Original Research

    1. Nonintravenous rescue medications for pediatric status epilepticus: A cost-effectiveness analysis

      Iván Sánchez Fernández, Marina Gaínza-Lein and Tobias Loddenkemper

      Version of Record online: 16 JUN 2017 | DOI: 10.1111/epi.13812

  19. Brief Communication

    1. Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol

      Evan C. Rosenberg, Jay Louik, Erin Conway, Orrin Devinsky and Daniel Friedman

      Version of Record online: 15 JUN 2017 | DOI: 10.1111/epi.13815

  20. Full-Length Original Research

    1. Use of the ketogenic diet to manage refractory epilepsy in CDKL5 disorder: Experience of >100 patients

      Zhan Lim, Kingsley Wong, Heather E. Olson, Ann M. Bergin, Jenny Downs and Helen Leonard

      Version of Record online: 12 JUN 2017 | DOI: 10.1111/epi.13813

  21. Brief Communication

  22. Full-Length Original Research

    1. Prediction of specific depressive symptom clusters in youth with epilepsy: The NDDI-E-Y versus Neuro-QOL SF

      Tanja S. Kellermann, Martina Mueller, Emma G. Carter, Byron Brooks, Gigi Smith, Olivia J. Kopp and Janelle L. Wagner

      Version of Record online: 9 JUN 2017 | DOI: 10.1111/epi.13808

  23. Brief Communication

    1. The prevalence of anxiety and associated factors in persons with epilepsy

      Tram Pham, Khara M. Sauro, Scott B. Patten, Samuel Wiebe, Kirsten M. Fiest, Andrew G. M. Bulloch and Nathalie Jetté

      Version of Record online: 9 JUN 2017 | DOI: 10.1111/epi.13817

  24. Full-Length Original Research

    1. An economic evaluation of a multicomponent self-management intervention for adults with epilepsy (ZMILE study)

      Ben F. M. Wijnen, Loes A. M. Leenen, Reina J. A. de Kinderen, Caroline M. van Heugten, Marian H. J. M. Majoie and Silvia M. A. A. Evers

      Version of Record online: 7 JUN 2017 | DOI: 10.1111/epi.13806

    2. Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2+/Q390X Dravet syndrome mice

      Xuan Huang, Chengwen Zhou, Mengnan Tian, Jing-Qiong Kang, Wangzhen Shen, Kelienne Verdier, Aurea Pimenta and Robert L. MacDonald

      Version of Record online: 6 JUN 2017 | DOI: 10.1111/epi.13810

    3. Abnormal γ-aminobutyric acid neurotransmission in a Kcnq2 model of early onset epilepsy

      Taku Uchida, Christoph Lossin, Yukiko Ihara, Masanobu Deshimaru, Yuchio Yanagawa, Susumu Koyama and Shinichi Hirose

      Version of Record online: 2 JUN 2017 | DOI: 10.1111/epi.13807

    4. Regulating drivers with epilepsy in Maryland: Results of the application of a United States consensus guideline

      Brandy B. Ma, John Bloch, Allan Krumholz, Jennifer L. Hopp, Perry J. Foreman, Carl A. Soderstrom, Mary A. Scottino, Martha Matsumoto and Gregory L. Krauss

      Version of Record online: 1 JUN 2017 | DOI: 10.1111/epi.13804

  25. Brief Communication

    1. Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome

      Jeffrey D. Calhoun, Nicole A. Hawkins, Nicole J. Zachwieja and Jennifer A. Kearney

      Version of Record online: 28 MAY 2017 | DOI: 10.1111/epi.13811

  26. Full-Length Original Research

    1. Early ictal and interictal patterns in FIRES: The sparks before the blaze

      Raquel Farias-Moeller, Luca Bartolini, Katelyn Staso, John M. Schreiber and Jessica L. Carpenter

      Version of Record online: 26 MAY 2017 | DOI: 10.1111/epi.13801


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