Cover image for Vol. 56 Issue 10

Edited By: Paul M. Ness

Impact Factor: 3.042

ISI Journal Citation Reports © Ranking: 2015: 30/70 (Hematology)

Online ISSN: 1537-2995

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Check out this article in Transfusion News on the Treatment of Transplant-Associated Thrombotic Microangiopathy. Read the related article "Treatment of thrombotic microangiopathy after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin" by Fujiwara et al in TRANSFUSION.

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Journal and Society News

Commentary Addresses RBC Guidelines

Don’t miss the commentary in the October issue on AABB’s revised clinical practice guidelines on Red Blood Cell (RBC) transfusion, published in JAMA. Since the original guidelines were issued in 2012, 15 new clinical trials have addressed the transfusion threshold for RBCs, doubling the clinical trial database..

The Red Blood Cells Transfusion Guidelines Work Group analyzed results from the new studies and developed the revised guidelines to serve as suggestions rather than inflexible rules. AABB emphasizes that good clinical practice involves considering “not only the hemoglobin level, but the overall clinical context and alternative therapies to transfusion.”

The commentary summarizes the two primary recommendations in the guidelines. The first is a restrictive RBC transfusion threshold of 7 g/dL for hospitalized, hemodynamically stable adults, including critical care patients. This threshold replaces the previous recommendation of 10 g/dL. For patients undergoing orthopedic or cardiac surgery, and those with preexisting cardiovascular disease, AABB recommends a restrictive transfusion threshold of 8 g/dL. The second recommendation is that patients — including neonates — receive standard issue rather than fresh (less than 10 days of storage) RBC units. The commentary concludes by identifying areas where future research needs to focus.


Earn Credits

Earn CME from Transfusion

TRANSFUSION is again offering continuing medical education (CME) credits for reading select articles in the journal and successfully completing a test on the content.These CME activities also meet the American Board of Pathology’s (ABP) Maintenance of Certification (MOC) requirements for Self-Assessment Modules (SAMs) [ACGME/MOC category: Medical Knowledge].

Physicians interested in completing the exam should log on to Upon successfully finishing the activity, physicians will receive an electronic certificate of completion, which can be printed and saved online under the user's profile.

The program is free to subscribers of the journal.


New Releases

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New AABB Releases

AABB has released several new resources, all of which are available at in the MarketPlace.

  • Investigating Positive DAT Results: A Case Study Approach. Written by Janis R. Hamilton, Susan T. Johnson, and Sally V. Rudmann. Online component provides questions without the answers for self-assessment.
  • BUNDLE: Investigating Positive DAT Results: A Case Study Approach AND Antibody Identification: Art or Science? Perfect companion texts from the same authors.
  • Patient Blood Management: Multidisciplinary Approaches to Optimizing Care. Edited by Jonathan Waters and Steve Frank. Available in print, digital, or both in a cost-saving bundle.
  • Cellular Therapy: Principles, Methods, and Regulations, 2nd ed. Edited by Ellen Areman and Kathy Loper. Available in print, digital, or both in a cost-saving bundle.
  • Standards for Molecular Testing for Red Cell, Platelet, and Antigen Testing, 3rd edition. Effective October 1, 2016. Available in print and via the Standards Portal.